ABSTRAK
Tujuan: Menentukan prevalensi excessive daytime sleepiness (EDS) pada pasiendengan epilepsi dan faktor-faktor yang berhubungan di Rumah Sakit CiptoMangunkusumo (RSCM).Metode: Studi potong lintang deskriptif ini menggunakan kuesioner EpworthSleepiness Scale (ESS) pada pasien epilepsi yang diambil secara konsekutif dipoliklinik neurologi RSCM, pada bulan Oktober-November 2015. Faktor-faktoryang dianalisis meliputi usia, jenis kelamin, jenis bangkitan, sindrom epilepsi,etiologi epilepsi, frekuensi bangkitan, bangkitan nokturnal, risiko ObstructiveSleep Apnea (OSA), depresi mayor, gangguan cemas menyeluruh, obat antiepilepsi, dan potensial resistensi obat. EDS ditentukan jika skor ESS > 10. RisikoOSA ditetapkan dengan kuesioner STOP-Bang; depresi mayor ditentukan dengankuesioner Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)versi Indonesia; gangguan cemas menyeluruh ditentukan dengan kuesioner MiniInternational Neuropsychiatric Interview for International Classification ofDiseases-10 (MINI ICD-10). Hasil: Diantara 93 pasien epilepsi, prevalensi EDS adalah sebanyak 32.3%;wanita lebih banyak dari pria. Faktor-faktor yang berhubungan secara signifikandengan EDS adalah usia kurang dari 35 tahun, frekuensi bangkitan dalam 1 tahunlebih dari sama dengan 8 kali, depresi mayor, dan potensial resisten obat. Darianalisis multivariat, terdapat 2 faktor independen yang berhubungan dengan EDSyaitu depresi mayor dan potensial resisten obat. Kesimpulan: EDS umum dijumpai pada pasien epilepsi dengan prevalensi32.3%. Depresi mayor dan potensial resistensi obat merupakan faktor yangberhubungan dengan EDS pada pasien epilepsi ABSTRACT
Purpose: To determine the prevalence of excessive daytime sleepiness (EDS) inepilepsy patients and its related factors at Cipto Mangunkusumo HospitalJakarta, Indonesia.Materials and Method: This cross-sectional descriptive study using EpworthSleepiness Scale (ESS) questionnaire to identify EDS in epilepsy patients visitedour neurology clinic during October-November 2015 consecutively. Relatedfactors that had been analyzed were age, sex, seizure type, epilepsy syndrome,etiology, seizure frequency, nocturnal seizures, risk of Obstructive Sleep Apnea(OSA), major depression, general anxiety disorder, anti epileptic drug, andpotentially drug resistant epilepsy (DRE). EDS was determined if ESS score > 10.Risk of OSA was assessed by STOP-Bang questionnaire; major depression wasassessed by Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)Indonesian version; general anxiety disorder was assessed by Mini InternationalNeuropsychiatric Interview for International Classification of Diseases-10 (MINIICD-10). Data analysis was done using SPSS 17.0.Results: Among 93 subjects, prevalence of EDS was 32.3%; female was morecommon than male. Related factors that significantly influenced to EDS were age< 35 years old, seizure frequency within 1 year >8 times, major depression andpotentially DRE. From multivariate analysis, there were 2 independent factorsthat related to EDS that were major depression and potentially DRE.Conclusions: EDS is common in epilepsy patients (32.3%). Major depression andpotentially DRE were related factors of EDS in epilepsy patients.;Purpose: To determine the prevalence of excessive daytime sleepiness (EDS) inepilepsy patients and its related factors at Cipto Mangunkusumo HospitalJakarta, Indonesia.Materials and Method: This cross-sectional descriptive study using EpworthSleepiness Scale (ESS) questionnaire to identify EDS in epilepsy patients visitedour neurology clinic during October-November 2015 consecutively. Relatedfactors that had been analyzed were age, sex, seizure type, epilepsy syndrome,etiology, seizure frequency, nocturnal seizures, risk of Obstructive Sleep Apnea(OSA), major depression, general anxiety disorder, anti epileptic drug, andpotentially drug resistant epilepsy (DRE). EDS was determined if ESS score > 10.Risk of OSA was assessed by STOP-Bang questionnaire; major depression wasassessed by Neurological Disorders Depression Inventory for Epilepsy (NDDI-E)Indonesian version; general anxiety disorder was assessed by Mini InternationalNeuropsychiatric Interview for International Classification of Diseases-10 (MINIICD-10). Data analysis was done using SPSS 17.0.Results: Among 93 subjects, prevalence of EDS was 32.3%; female was morecommon than male. Related factors that significantly influenced to EDS were age< 35 years old, seizure frequency within 1 year >8 times, major depression andpotentially DRE. From multivariate analysis, there were 2 independent factorsthat related to EDS that were major depression and potentially DRE.Conclusions: EDS is common in epilepsy patients (32.3%). Major depression andpotentially DRE were related factors of EDS in epilepsy patients. |
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