Sintesis interleukin 1B sel makrofag mencit yang diinduksi lipopolisakarida E. coli dan minyak atsiri kencur (kaempferia galanga L.) in vitro
([Fakultas Kedokteran Gigi, Journal of Dentistry Indonesia], 2007)
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| The purpose of this study was to evaluate the effectiveness of the essential oil of Kaempheria galangal as an anti-inflammatory agent, by evaluating its effect on interleukin 1B (IL-1B ???), produced by lipopolysaccharide (LPS) E. coli stimulated macrophages. Macrophage cells were stimulated with LPS E. coli and essential oil of Kaempheria galangal at concentrations of 3 ul/ml, 1.5 ul/ml, 0.75 ul/ml and 0.25 ul/ml. All of the treatment groups were incubated at 37°C in an atmosphere containing 5% CO2 for 24 hours. The concentrations of IL-1B supernatant were determined by using an enzyme-linked immunosorbent assay kit. Statistical analysis using ANOVA showed significant differences between the treatment groups (p<0.05). This study indicates that the essential oil of Kaempheria galangal suppressed IL-1B produced by LPS E. coli stimulated macrophage cells. |
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| Penerbitan : | [Place of publication not identified]: [Fakultas Kedokteran Gigi, Journal of Dentistry Indonesia], 2007 |
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| Majalah/Jurnal : | Journal of Dentistry Indonesia |
| Volume : | Vol. 14, No. 3, Desember 2007: 194-198 |
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| Institusi Pemilik : | Universitas Indonesia |
| Lokasi : | Fakultas Kedokteran Gigi |
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