:: Majalah, Jurnal, Buletin :: Kembali

Majalah, Jurnal, Buletin :: Kembali

Journal of pharmaceutical sciences

(Department of Pharmaceutical Chemistry The University of Kansas, 2018)

 Abstrak

ABSTRAK
Delivery of pharmacological doses of proteins to people has raised concerns of inducing immune responses, especially when the protein is provided in multiple doses over an extended period of time. Immune responses could impact the therapeutic exposure and efficacy of the protein itself. In addition, there have been fears of anaphylaxis or autoimmunity. This review summarizes the available literature regarding the measurement and evaluation of immune responses observed during clinical assessment of recombinant human proteins. Immune responses have ranged from none at all to inactivation and/or accelerated clearance. Presence of antibodies does not necessarily impact therapeutic viability. While responses are related to frequency and route of delivery, there is no clear relationship that enables one to predict the clinical experience.

 Metadata

No. Panggil : 615 JPS
Subjek :
Penerbitan : Washington DC: Department of Pharmaceutical Chemistry The University of Kansas, 2018
Sumber Pengatalogan LibUI eng rda
Tipe Konten text
Tipe Media unmediated
Tipe Carrier volume
Deskripsi Fisi
Kepemilikan
Lembaga Pemilik Universitas Indonesia
Lokasi Perpustakaan UI, Lantai 4, R. Koleksi Jurnal
  • Ketersediaan
  • Ulasan
No. Panggil No. Barkod Ketersediaan
615 JPS 04-19-028294206 TERSEDIA
615 JPS 04-18-361728390 TERSEDIA
615 JPS 04-18-083421333 TERSEDIA
615 JPS 04-18-477701619 TERSEDIA
615 JPS 04-18-483219748 TERSEDIA
615 JPS 04-18-950821868 TERSEDIA
615 JPS 04-18-797906467 TERSEDIA
615 JPS 04-18-965486199 TERSEDIA
615 JPS 04-18-190556460 TERSEDIA
615 JPS 04-18-084619420 TERSEDIA
615 JPS 04-18-974143201 TERSEDIA
615 JPS 04-18-805875586 TERSEDIA
615 JPS 04-18-326838117 TERSEDIA
615 JPS 04-18-006025012 TERSEDIA
615 JPS 04-18-209241839 TERSEDIA
615 JPS 04-18-198302131 TERSEDIA
615 JPS 04-18-782171055 TERSEDIA
615 JPS 04-18-669308280 TERSEDIA
615 JPS 04-18-743659091 TERSEDIA
615 JPS 04-18-658221059 TERSEDIA
615 JPS 04-18-201063314 TERSEDIA
615 JPS 04-18-113153663 TERSEDIA
615 JPS 04-18-113153663 TERSEDIA
615 JPS 04-18-268888897 TERSEDIA
615 JPS 04-18-090038201 TERSEDIA
615 JPS 04-18-385209758 TERSEDIA
615 JPS 04-18-047260595 TERSEDIA
615 JPS 04-18-487083420 TERSEDIA
615 JPS 04-18-597421899 TERSEDIA
615 JPS 04-18-365437567 TERSEDIA
615 JPS 04-18-497752409 TERSEDIA
615 JPS 04-18-876695780 TERSEDIA
615 JPS 04-18-805333278 TERSEDIA
615 JPS 04-18-915513482 TERSEDIA
Ulasan:
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