Evaluasi ekonomi cost-outcome pada skrining dan terapi dini hipotiroid kongenital di Indonesia 2014 -2015 = Cost and outcome of screening and early
theraphy of congenital hypothyroidism in Indonesia 2014-2015 / Farsely Mranani

Farsely Mranani, author

Evaluasi ekonomi cost-outcome pada skrining dan terapi dini hipotiroid kongenital di Indonesia 2014 -2015 = Cost and outcome of screening and early theraphy of congenital hypothyroidism in Indonesia 2014-2015 / Farsely Mranani

Farsely Mranani; Mardiati Nadjib, supervisor; Pujiyanto, examiner; Yetty Yulianty Permanasari, examiner; Erna Mulati, examiner; Nindya Savitri, examiner ([Publisher not identified] , 2016)

Abstrak

ABSTRAK

Hipotiroid kongenital (HK) adalah kelainan bawaan yang dapat menimbulkan

dampak berupa retardasi mental permanen. Pemberian levothyroxine dengan dosis

tepat pada usia sedini mungkin, dapat mencegah gangguan pertumbuhan dan

perkembangan. Sayangnya, bayi baru lahir tidak menunjukkan gejala HK. Kalaupun

ada, berarti sudah ada gangguan pertumbuhan. Perlu skrining hipotiroid kongenital

(SHK) untuk menemukan kasus bayi yang menderita HK.

Meski sudah dilakukan sejak 2006, baru pada tahun 2014 dikeluarkan Permenkes

tentang pelaksanaan SHK di Indonesia. Penelitian evaluasi ekonomi program SHK

tahun 2014-2015 ini mencakup analisis biaya skrining dan terapi dini, sedangkan

outcome didapat dari systematic review (SR). Asumsi dikembangkan berdasarkan

data riil pasien skrining SHK di 2 laboratorium rujukan di Jakarta dan Bandung.

Dari total 56.186 bayi yang melakukan skrining, diperoleh 24 pasien positif

menderita HK.

Hasil SR menyatakan bahwa semakin dini onset terapi, semakin adekuat dosis

inisiasi dan semakin kontinyu terapi dapat memberikan hasil yang baik. Hasil

tersebut berupa pencegahan terhadap komplikasi HK lebih jauh dan perbaikan pada

penyimpangan tumbuh kembang.

Dari hasil penelitian, didapatkan informasi bahwa baru pada tahun kedua terlihat

adanya keuntungan ekonomis SHK. Hal ini berhubungan dengan patologi gejala HK

yang umumnya muncul pada usia 3-6 bulan. Orang tua baru mencari pertolongan

medis pada tahun kedua dan mengeluarkan lebih banyak biaya. Biaya skrining dan

terapi dini menjadi sepadan dibandingkan dengan kerugian yang dapat dicegah

akibat gejala gangguan tumbuh kembang.

ABSTRACT

Congenital hypothyroidism (CH) is a congenital disorder that can have an impact in

the form of permanent mental retardation. Giving the right dose of levothyroxine at

the earliest possible age, can prevent the disruption of growth and development.

Newborns do not show symptoms of CH, and unfortunately the symptoms appear in

the late period and in many cases it shows growth disorders. The congenital

hypothyroidism screening (CHS) program has been implemented to find infant cases

with CH, and followed up with treatment.

Although it has been made since 2006, Minister of Health just issued the regulation

in 2014 on the implementation of CHS in Indonesia. This economic evaluation of the

CHS program in 2014-2015 was done using cost analysis, while outcome obtained

from the systematic review (SR). The assumptions used in the analysis were

developed based on real data from a CHS screening program in two referral

laboratories in Jakarta and Bandung. Out of 56.186 screened babies, 24 babies were

found as CH positive cases.

The result of the SR revealed that the earlier onset of initiation therapy, the more

adequate dose and the more continuous therapy given to the patient, the better result

will be achieved. It will prevent the patients from severe complications of CH and

will improve the quality of thegrowth and development..

The study found that the economic benefit is achieved in the second year of CH

treatment, since the pathological symptoms generally appear at the age of 3-6 month

and parents seek care in the second year. Consequently, cost to treat patients will

increase. The cost of screening and early treatment was found worthy as compared to

economic loss resulting from growth disorders.

File Digital: 1

Shelf

T47178-Farsely Mranani.pdf :: Unduh

LOGIN required

Kata Kunci

congenital hypothyroid screening

cost

outcome

biaya

luaran

Metadata

No. Panggil :	T47178
Entri utama-Nama orang :	Farsely Mranani, author


Entri tambahan-Nama orang :	Mardiati Nadjib, supervisor Pujiyanto, examiner Yetty Yulianty Permanasari, examiner Erna Mulati, examiner Nindya Savitri, examiner
Entri tambahan-Nama badan :	Universitas Indonesia. Fakultas Kesehatan Masyarakat

Subjek :	Congenital hypothyroidism Congenital Hypothyroidism -- Therapy
Penerbitan :	[Place of publication not identified]: [Publisher not identified], 2016
Program Studi :	Ilmu Kesehatan Masyarakat

Bahasa :	ind
Sumber Pengatalogan :	LibUI ind rda
Tipe Konten :	text
Tipe Media :	unmediated ; computer
Tipe Carrier :	volume ; online resource
Deskripsi Fisik :	xii, 79 pages : illustration ; 28 cm + appendix,
Naskah Ringkas :
Lembaga Pemilik :	Universitas Indonesia
Lokasi :	Perpustakaan UI, Lantai 3

Ketersediaan
Ulasan

No. Panggil	No. Barkod	Ketersediaan
T47178	15-19-541728387	TERSEDIA

Ulasan:

Tidak ada ulasan pada koleksi ini: 20451139

:: UI - Tesis Membership :: Kembali