ABSTRAK TB merupakan tantangan bagi pengendalian Acquired ImmunodeficiencySyndrome (AIDS) karena merupakan infeksi oportunistik terbanyak pada orangdengan HIV/AIDS (ODHA). TB dapat meningkatkan progresivitas HIV danmeningkatkan risiko kematian bagi penderita HIV. Tujuan penelitian ini adalahuntuk mengetahui prediktor yang berhubungan dengan kejadian TB pada ODHAdi RS dr. H. Marzoeki Mahdi Bogor Tahun 2014-2016. Desain studi yangdigunakan adalah cross sectional dengan menggunakan data register ART danRekam Medis.Sampel berjumlah 817 pasien HIV. Analisis data dilakukan denganmengguunakan multiple cox regression. Hasil analisis multivariat menunjukkanadanya peningkatan risiko TB pada kelompok dengan anemia (PR=1,60, 95% CI:1,18-2,29) dibandingkan kelompok tanpa anemia, adanya status IO (PR=4,83,95% CI: 2,30-10,61) dibandingkan kelompok tanpa IO, stadium HIV 3-4(PR=6,38, 95% CI: 3,22-12,65) dibandingkan stadium HIV 1-2 dan kadar CD4dengan nilai PR masing masing kategori: kadar 350-499 Vs ≥500 (PR=2,52, 95%CI: 0,33-19,34), kadar 200-349 Vs ≥500 (PR=2,71, 95% CI: 0,36-20,23), kadar<200 Vs ≥500 (PR=3,31, 95% CI: 0,45-24,37).Selain itu ditemukan adanyainteraksi antara variabel stadium HIV dan status IO. ABSTRACT TB is a challenge for the control of Acquired Immunodeficiency Syndrome (AIDS)because it is the most common opportunistic infection in people living with withHIV (PLWH). TB increase HIV progressivity and increase the risk of death forPLWH. The purpose of this study is to determine the predictors are associatedwith TB among PLWH in RS dr. H. Marzoeki Mahdi Bogor, 2014-2016. Studydesign was cross sectional using ART register data and Medical Record. Totalsample of 817 HIV patients were collected. Multiple cox regression analysis wereapplied in this research. The results of multivariate analysis showed an increasedrisk of TB in the group with anemia (PR = 1.60, 95% CI: 1.18-2.29) compared tothe group without anemia, group with IO (PR = 4,83, 95% CI: 2,30-10,61) thanthose without IO, HIV stage 3-4 (PR = 6,38, 95% CI: 3,22-12,65) than HIV stage1-2, and CD4 levels with PR for each category: levels of 350-499 vs ≥500 (PR =2.52, 95% CI: 0.33-19.34), levels of 200-349 vs ≥500 (PR = 2.71, 95% CI: 0.36-20.23), levels <200 vs ≥500 (PR = 3.31, 95% CI: 0.45-24.37). In addition, therewas an interaction between HIV stage and IO. |