Latar belakang: Refluks laringofaring LPR merupakan penyakit komorbid laringomalasia terbanyak, sehingga tata laksana laringomalasia mencakup penanganan LPR. Tujuan: Mengetahui karakteristik pasien, hubungan keteraturan berobat, dosis penghambat pompa proton PPI , dan faktor lain yang memengaruhi perbaikan klinis laringomalasia. Metode: Penelitian kohort retrospektif berdasarkan rekam medis. Subjek penelitian dipilih secara total sampling. Hasil: Total subjek adalah 95 rekam medis. Usia median pasien 3 bulan. Mayoritas pasien adalah lelaki, lahir cukup bulan, berat lahir cukup. Pada awal diagnosis, sebagian besar berstatus gizi baik, tidak gagal tumbuh, mengalami laringomalasia tipe 1, berderajat klinis sedang, skor gejala laringomalasia positif LSS , mengalami gejala refluks, tanpa pipa nasogastrik, tidak teratur berobat, dan mendapat PPI ge;1,0mg/kg/hari. Penyakit penyerta yang terbanyak adalah kelainan neurologi dan yang terjarang adalah penyakit refluks. Pasien yang berobat teratur mengalami perbaikan status gizi p=0,020 , derajat laringomalasia p=0,043 , nilai LSS p=0,002 , gejala refluks.
Background Laryngopharyngeal refluks LPR is laryngomalacia rsquo s most common comorbidity. Laryngomalacia management includes LPR treatment. Aim To describe the characteristics of patients, relationships of compliance, proton pump inhibitor PPI dosage, and other factors that contribute to clinical improvements. Methods Cohort retrospective study based on medical records. Subjects is recruited by total sampling. Results Total subject consists of 95 medical records. Median age is 3 months, majority are boys, born aterm, normal birth weight. Most patients are well nourished, thrive well, experienced type 1 laryngomalacia, moderate degree, positive laryngomalacia symptom score LSS , experienced reflux symptoms, did not require feeding tube, poor compliance to medication, and prescribed PPI ge 1,0mg kg day. The most common recorded comorbidity is neurologic abnormality, while the most infrequent is reflux. Good compliance is related to improvements of nutritional status p 0,020 , degree p 0,043 , LSS p 0,002 , reflux symptom p |
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