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Pengembangan metode analisis captopril menggunakan screen printed electrode (SPE) termodifikasi tembaga (Cu) dengan sistem alir (flow injection analysis/ FIA) = Development of captopril analysis method using copper (Cu) modified screen printed electrode (SPE) using flow injection analysis (FIA)

Rachel Hardiari Krisjantiarum; Rahmat Wibowo, supervisor; Dita Arifa Nurani, supervisor; Endang Saefudin, examiner; Asep Saefumillah, examiner; Helmiyati, examiner (Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2018)

 Abstrak

Using enzymatic sensor to determine the level of captopril is an alternative method that is being widely developed. In research , made in captopril sensor using Screen Printed Electrode (SPE), because of its advantage of being practical and simple. Cu electrodeposition on SPE is being done by potential -0,480 V vs Ag½AgCl with variation of time deposition of 5, 30 and 60 second. This research finds that the optimum deposition time is 60 second by taking into loading amount of 6,92 x 10-6 gr.cm-2. Cu/SPE is then applied to the Flow Injection Analysis (FIA) system. The optimum result of sensor appears in the FIA system with at the flow rate of 0,5 mL/minute and KOH Concentration of 1 M. Cu/SPE Sensor in FIA system has LOD of 6,530 x 10-6 M and sensitivity of 308,80 μA.mM-1.cm-2. Cu/SPE sensor has good repeatability with value linearity of 0,9113 and %RSD of 1,75%. Selectivity test on the captopril to the glucose and lactose may produce better sensor. The application of Cu/SPE sensor has value %recovery of 96,29%.

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No. Panggil : S-Pdf
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Subjek :
Penerbitan : Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2018
Program Studi :
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : xvii, 40 pages : illustration ; appendix
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI. Lantai 3
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No. Panggil No. Barkod Ketersediaan
S-Pdf 14-19-063326517 TERSEDIA
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