ABSTRACT
Curcumin is an active ingredient obtained from the turmeric plant and has been reported to havemany biological activities as anti cancer, an anti-inflammatory, antimicrobial and antioxidant although itsclinical use is limited because of its poor solubility in water and inadequate dissolution. Objective- The aimof this research is to prepare dry dispersible emulsion (DDE) of curcumin and to know its effect on enhancingthe dissolution rate of curcumin. Method-The dry dispersible emulsion was prepared byusing a high-speedhomogenization and ultrasonic technique. Caseinate sodium was used as the surfactant while virgin coconutoil was used as the lipid. Dispersion of the dry emulsion was then spray dried. Dry dispersible emulsionpowder was characterized and compared with standard curcumin. Result-The DSC test showed a significantdecrease in the melting point. Conclusion-The dissolution rate of curcumin can be significantly improvedwith a dry dispersible emulsion formulation. In formula A and formula C, the maximum dissolved curcuminincreased by 83.65%, 81.53% in formula B, and 79.12% in formula C |
