Long-term outcomes after an aggressive resection of adenosquamous carcinoma of the pancreas
Takaaki Ito;
Teiichi, Sugiura; Yukiyasu Okamura; Yusuke Yamamoto; Ryo Ashida; Katsuhisa Ohgi; Keiko Sasaki; Uesaka, Katsuhiko
(Springer, 2019)
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ABSTRACT Purpose Adenosquamous carcinoma (ASC) of the pancreas is a rare malignancy, associated with a poor prognosis after surgical resection, with reported median survival times (MSTs) ranging from 4.4 to 13.1 months. We conducted this study to investigate the long-term outcomes of patients after the resection for ASC.MethodsBetween 2002 and 2016, a total of 456 patients underwent resection for ASC or adenocarcinoma (AC) of the pancreas. ASC was confirmed in 17 (3.7%) of these patients. We analyzed the clinicopathological characteristics and survival of these 17 patients in comparison with those of patients with AC of the pancreas.ResultsThe operative procedures performed were pancreaticoduodenectomy (n = 6) and distal pancreatectomy (n = 11). Seven (41.2%) of the 17 patients underwent combined organ resection. R0 resection was achieved in 16 (94.1%) patients. The 5-year overall survival (OS) rate and MST were 40.3% and 20.9 months, respectively. A squamous component of ≥ 60% (P = 0.001) and R1 resection (P < 0.001) were significantly associated with poor OS for patients with ASCConclusionThis study revealed longer survival and a higher R0 resection rate after aggressive combined resection in our ASC patients than those in previous studies. Although this was only a small series, our findings suggest that local control with aggressive resection may be an effective treatment protocol for ASC patients. |
| No. Panggil : | 617 SUT 49:10 (2019) |
| Entri utama-Nama orang : | |
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| Penerbitan : | Tokyo: Springer, 2019 |
| Sumber Pengatalogan : | LibUI eng rda |
| ISSN : | 09411291 |
| Majalah/Jurnal : | Surgery Today Official Journal of The Japan Surgical Society |
| Volume : | Vol. 49 No. 10, October 2019: Hal. 809-819 |
| Tipe Konten : | text |
| Tipe Media : | unmediated |
| Tipe Carrier : | volume |
| Akses Elektronik : | https://link.springer.com/article/10.1007/s00595-019-01807-8 |
| Institusi Pemilik : | Universitas Indonesia |
| Lokasi : | Perpustakaan UI, Lantai 4, R. Koleksi Jurnal |
| No. Panggil | No. Barkod | Ketersediaan |
|---|---|---|
| 617 SUT 49:10 (2019) | 03-20-249535486 | TERSEDIA |
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| Tidak ada ulasan pada koleksi ini: 20502993 |
