Kanker prostat adalah angka kematian terkait kanker tertinggi kedua pada pria setelahkanker paru-paru. Neutrophyl to lymphocyte ratio (NLR), salah satu parameterinflamasi, ditemukan sebagai faktor prognostik pada beberapa jenis tumor padat,seperti kanker prostat. Penelitian ini bertujuan untuk menilai ada tidaknya hubunganantara NLR dengan hasil skor Gleason pasien biopsi adenokarsinoma prostat di RSUDHaji Adam Malik Medan. Sebanyak 121 pasien menjalani biopsi prostat dari awalJanuari 2013 - Desember 2015 di RS Adam Malik dan 30 tidak dikeluarkan. Data dari91 pasien kemudian diambil meliputi umur, data hematologi pra biopsi, pemeriksaanPSA awal, estimasi berat prostat, dan skor gleason dari hasil biopsi. Data diolah denganSPSS versi 22. Ditemukan pasien dengan usia rata-rata 68,34 tahun dengan rentang usia52-85 tahun. Tidak ada hubungan bermakna antara NLR dan TBP dengan r = 0,077 danp = 0,469 serta tidak ada hubungan bermakna antara NLR dan PSA dengan r = 0,072dan p = 0,496. Ada hubungan yang signifikan antara rasio neutrofil / limfosit denganhasil pemeriksaan gleason score pada pasien kanker prostat di RSUP Haji Adam Malik.Diperlukan penelitian lebih lanjut, apakah rasio neutrofil / limfosit dapat digunakanuntuk memprediksi skor gleason score pada pasien suspek kanker prostat
Prostate cancer is the second highest cancer-related mortality rate in men after lungcancer. Neutrophyl to lymphocyte ratio (NLR), one of the inflammatory parameters, isfound as a prognostic factor in several types of solid tumors, such as prostate cancer.This study aims to assess whether there is a correlation between NLR with the resultsof Gleason score of patients with prostate adenocarcinoma biopsy at Haji Adam MalikHospital Medan. A total of 121 patients underwent a prostate biopsy from early January2013 - December 2015 at Adam Malik Hospital and 30 were not excluded. Data from91 patients were then taken, including age, hematologic data pre biopsy, PSA on initialexamination, prostate weight estimation, and gleason score from biopsy results. Thedata is processed with SPSS version 22. We found patients with a mean age of 68.34years with an age ranging from 52 to 85 years. There is no significant correlationbetween NLR and TBP with r = 0.077 and p = 0.469 and also there is no significantcorrelation between NLR and PSA with r = 0.072 and p = 0.496. There is a significantcorrelation between the ratio of neutrophils/lymphocytes with the results of gleasonscore examination in prostate cancer patients at Haji Adam Malik Hospital. Furtherstudies are needed, whether the ratio of neutrophils / lymphocytes can be used to predictthe gleason score score in patients with suspected prostate cancer. |
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