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Performa Penapisan Instrumen Mini Sarcopenia Risk Assessment (MSRA) dan Instrumen MSRA-LB Terhadap Diagnosis Sarkopenia pada Pasien Lanjut Usia = The Screening Performance of Mini Sarcopenia Risk Assessment (MSRA) and MSRA-CC Instruments to Diagnose Sarcopenia in Elderly Patients

Fredia Heppy; Arya Govinda Rooshoeroe, supervisor; Noto Dwimartutie, supervisor; Muhadi, supervisor; Imam Subekti, examiner; Marbun, Maruhum Bonar H., examiner; Nina Kemala Sari, examiner; Harry Isbagio, examiner; Hamzah Shatri, supervisor (Fakultas Kedokteran Universitas Indonesia, 2023)

 Abstrak

Latar Belakang: Sarkopenia merupakan sindroma geriatri baru tertinggi dengan luaran klinis yang buruk, sehingga perlu dilakukan penapisan. Instrumen penapisan standar memiliki sensitivitas yang rendah. Mini Sarcopenia Risk Assessment (MSRA) merupakan instrumen baru dengan performa penapisan beragam, sehingga perlu diteliti lagi. Penambahan lingkar betis (LB) pada MSRA diharapkan mendapatkan hasil penapisan yang lebih baik.
Tujuan: Mengetahui performa penapisan instrumen MSRA dan MSRA-LB terhadap diagnosis sarkopenia pada pasien lansia.
Metode: studi potong lintang dengan subjek lansia di Poliklinik Terpadu Geriatri, Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo telah dilakukan bulan Oktober hingga Desember 2022. Data diambil melalui wawancara dan pemeriksaan antropometri, LB, kekuatan genggaman tangan, indeks massa otot apendikular, dan penilaian performa fisik.
Hasil: Diperoleh subjek sebesar 118 pasien dengan proporsi sarkopenia sebesar 19 pasien (16,1%) berdasarkan AWGS 2019. Sensitivitas instrumen MSRA-7, MSRA-5, MSRA-7-LB dan MSRA-5-LB secara berurutan adalah 78,95%, 57,89%, 57,89% dan 42,11%. Sedangkan spesifisitas adalah 30,30%, 46,46%, 87,88% and 93,94%. Model MSRA-LB meningkatkan akurasi diagnosis secara bermakna p=0,003 pada MSRA-7-LB dan p= 0,005 pada MSRA-5-LB p=0,00.
Simpulan: Performa penapisan intrumen MSRA memiliki sensitivitas tinggi pada versi 7 butir pertanyaan. Penambahan lingkar betis memperbaiki akurasi diagnosis instrumen MSRA namun tidak meningkatkan sensitivitas instrumen.

Background: Sarcopenia were the highest prevalence in current geriatric syndrome with unfavorable clinical outcomes and standardized tools to screen was unsensitive. Mini Sarcopenia Risk Assessment (MSRA) has been developed to screen sarcopenia. Even, the performance is inconsistent, that is needed to be evaluated. Adding of calf circumference (CC) was conducted to find better screening performance.
Objective: To determine the screening performance of the MSRA and MSRA-CC instruments.
Methods: A cross-sectional study was conducted in elderly outpatients Cipto Mangunkusumo Central General Hospital, from October to December 2022. Data were collected through interviews and anthropometric examinations, measurements of body weight, hand grip strength, appendicular muscle mass index, and physical performance.
Result: Eligible subjects was 118 patients base on inclusion criteria. Sarcopenia were found 19 (16,1%) subjects based on the 2019 AWGS criteria. The sensitivity values of MSRA-7, MSRA-5, MSRA-7-CC, MSRA-5-CC were 78,95%, 57,89%, 57,89% and 42,11%, respectively. The specificities were 30,30%, 46,46%, 87,88% and 93,94%, respectively. Combination MSRA-CC improved diagnostic accuracy with p value of 7 and 5 version 0,003 and 0,005, respectively.
Summary: The high sensitivity screening performance of MSRA has been found in 7 item questions version. Combination MSRA-CC improved diagnostic accuracy of sarcopenia without increasing of sensitivity those instruments.

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 Metadata

No. Panggil : T-pdf
Entri utama-Nama orang :
Entri tambahan-Nama orang :
Entri tambahan-Nama badan :
Subjek :
Penerbitan : Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
Program Studi :
Bahasa : ind
Sumber Pengatalogan : LibUI ind rda
Tipe Konten : text
Tipe Media : computer
Tipe Carrier : online resource
Deskripsi Fisik : vii, 77 pages ; illustration ; 28 cm + appendix
Naskah Ringkas :
Lembaga Pemilik : Universitas Indonesia
Lokasi : Perpustakaan UI
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