Kadar Human Beta Defensin-1 pada Penderita Periodontitis Kronis dan Periodontitis Agresif dalam Cairan Krevikular Gingiva = Level of Human Beta Defensin-1 in Patients with Chronic Periodontitis and Aggressive Periodontitis in Gingival Crevicular Fluid
Sugiharto Wijaya;
Sri Lelyati C. Masulili, supervisor; Fatimah Maria Tadjoedin, supervisor; Elza Ibrahim Auerkari, supervisor; Hari Sunarto, examiner; Yuniarti Soeroso, examiner; Lessang, Robert, examiner
(Fakultas Kedokteran Gigi Universitas Indonesia, 2016)
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Latar Belakang: Kerusakan jaringan periodontal terjadi karena inflamasi terhadap invasi bakteri. Human beta defensin-1 adalah peptida antimikroba dan pertahanan pertama terhadap infeksi.Tujuan Penelitian: Membandingkan kadar ekspresi HBD-1 antara kelompok periodontitis kronis, periodontitis agresif dan normalBahan dan Metode: Kadar HBD-1 dari 94 sampel CKG subjek periodontitis kronis, periodontitis agresif dan normal diukur dengan ELISAHasil: Analisis Mann-Whitney menunjukkan perbedaan kadar HBD-1 antara periodontitis kronis dengan normal (p<0,05) dan tidak terdapat perbedaan signifikan (p>0,05) antara periodontitis agresif dengan normal, dan antara periodontitis kronis dengan periodontitis agresif.Kesimpulan: Kadar HBD-1 pada CKG menurun pada kondisi periodontitis kronis dan periodontitis agresif. Background: Periodontal disease is happened because inflammation reaction ro bacterial invasion. Human beta defensin-1 (HBD-1) is antimicroba peptide which regulate the first defense mechanism.Objectives: To compare level of HBD-1 between chronic periodontitis, aggressive periodontitis, and normal group.Material and Methods: Level of HBD-1 from GCF sample of chronic periodontitis, aggressive periodontitis, and normal group were assessed with ELISA.Results: Mann-Whitney analysis show different level of HBD-1 expression between chronic periodontitis and normal (p<0,05) and there was no significant difference (p>0,05) between aggressive periodontitis and normal, and between chronic periodontitis and aggressive periodontitis.Conclusion: Level of HBD-1 in GCF decreased in chronic periodontitis and aggressive periodontitis. |
 T-Sugiharto Wijaya.pdf :: Unduh
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| No. Panggil : | T-pdf |
| Entri utama-Nama orang : | |
| Entri tambahan-Nama orang : | |
| Entri tambahan-Nama badan : | |
| Subjek : | |
| Penerbitan : | Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2016 |
| Program Studi : |
| Bahasa : | ind |
| Sumber Pengatalogan : | LibUI ind rda |
| Tipe Konten : | text |
| Tipe Media : | computer |
| Tipe Carrier : | online resource |
| Deskripsi Fisik : | xiii, 43 pages : illustration + appendix |
| Naskah Ringkas : | |
| Lembaga Pemilik : | Universitas Indonesia |
| Lokasi : | Perpustakaan UI |
| No. Panggil | No. Barkod | Ketersediaan |
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| T-pdf | 15-23-66992806 | TERSEDIA |
| Ulasan: |
| Tidak ada ulasan pada koleksi ini: 9999920533415 |
