Mathematical model controlled potassium chloride release systems from chitosan microspheres
Widodo Wahyu Purwanto, Kamarza Mulia, Praswasti PDK Wulan, Ismail Marzuki , Mubarokah N. Dewi (Faculty of Engineering, Universitas Indonesia, 2015)
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| Chitosan can be prepared in the form of microspheres that serve as a depot for bioactive compounds released in a controlled way to diseased organs. In this study, a mathematical model of potassium chloride release from chitosan microspheres was developed. The model was validated using experimental data. The potassium chloride-loading percentages of 10.01%, 20.84%, and 20.57% were prepared using a cross-linking method. The potassium chloride loading was kept constant at about 20% when the potassium chloride mass in the preparation stage was above 5.024 mg/mL. Experiments and a model calculation of potassium chloride release from the microspheres with a loading of 10.01% and 20.57% were performed. In general, the model reproduces the experimental data. The experiments and the calculation show that during the same period, microspheres containing more potassium chloride release a higher percentage of potassium chloride than do microspheres containing less potassium chloride. |
| No. Panggil : | UI-IJTECH 6:7 (2015) |
| Entri utama-Nama orang : | |
| Subjek : | |
| Penerbitan : | Depok: Faculty of Engineering, Universitas Indonesia, 2015 |
| Sumber Pengatalogan : | LibUI eng rda |
| ISSN : | 20869614 |
| Majalah/Jurnal : | International Journal of Technology |
| Volume : | Vol. 6, No. 7, December 2015: Hal. 1228-1237 |
| Tipe Konten : | text |
| Tipe Media : | unmediated |
| Tipe Carrier : | volume |
| Akses Elektronik : | https://doi.org/10.14716/ijtech.v6i7.1847 |
| Institusi Pemilik : | Universitas Indonesia |
| Lokasi : | Perpustakaan UI, Lantai 4 R. Koleksi Jurnal |
| No. Panggil | No. Barkod | Ketersediaan |
|---|---|---|
| UI-IJTECH 6:7 (2015) | 08-23-27224765 | TERSEDIA |
| Ulasan: |
| Tidak ada ulasan pada koleksi ini: 9999920535755 |
