Ditemukan 51 dokumen yang sesuai dengan query
Boca Raton: CRC Pres/Taylor & Francis Group, 2009
615.7 GEN
Buku Teks Universitas Indonesia Library
Tsaioun, Katya, editor
This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of...
New Jersey: John Wiley & Sons, 2011
e20375655
eBooks Universitas Indonesia Library
This book discuss early characterization of toxicity and efficacy would significantly impact the overall productivity of pharmaceutical R&D and reduce drug candidate attrition and failure. By describing the available platforms and weighing their relative advantages and disadvantages and including microarray data analysis....
Hoboken, New Jersey: John Wiley & Sons, 2009
e20393938
eBooks Universitas Indonesia Library
This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and...
Hoboken, New Jersey: John Wiley & Sons, 2008
e20394421
eBooks Universitas Indonesia Library
Prazeres, Duarte Miguel F., author
The book addresses the basics, applications, and manufacturing of plasmid biopharmaceuticals. The survey of the most relevant characteristics of plasmids provides the basics for designing plasmid products (applications) and processes (manufacturing). Key features that the authors include in the book are: i) consistency and clear line of direction, ii) an...
Hoboken: John Wiley & Sons, 2011
e20394497
eBooks Universitas Indonesia Library
The book closes with chapters on recent progress in technologies: protein engineering to promote crystallization, micro-crystallization, and high-throughput crystallography. Withitsbroadperspective,thebookprovidesastate-of-the-artoverviewonimportant results and techniques that are relevant for protein 3D structure-based drug design...
Weinheim, Germany: Wiley-VCH, 2004
e20394586
eBooks Universitas Indonesia Library
This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examples of biosimulated cells, organs and organisms.
Following an introduction to the role of biosimulation in drug development, the authors go on to discuss the simulation...
Weinheim, Germany: Wiley-VCH, 2008
e20395821
eBooks Universitas Indonesia Library
The essentials of drug metabolism vital to developing new therapeutic entities.
Information on the metabolism and disposition of candidate drugs is a critical part of all aspects of the drug discovery and development process. Drug metabolism, as practiced in the pharmaceutical industry today, is a complex, multidisciplinary field that requires knowledge...
Hoboken, New Jersey: John Wiley & Sons, 2008
e20395867
eBooks Universitas Indonesia Library
This book covers both recent advances in the design and synthesis of new drugs, as well as the myriad other issues facing a new drug candidate as it moves through the development process. Utilizing recent case studies, the authors provide valuable insights into the complexities of the process, from designing...
Hoboken, New Jersey: Wiley-Interscience, 2006
e20395907
eBooks Universitas Indonesia Library
Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals.
In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution...
Weinheim, Germany: Wiley-VCH, 2006
e20395925
eBooks Universitas Indonesia Library
