Ditemukan 16 dokumen yang sesuai dengan query
Many drugs and other xenobiotics (e.g., preservatives, insecticides, and plastifiers) contain hydrolyzable moieties such as ester or amide groups. In biological media, such foreign compounds are, therefore, important substrates for hydrolytic reactions catalyzed by hydrolases or proceeding non-enzymatically.
Despite their significance, until now, no book has been dedicated to hydrolysis...
Weinheim, Germany: Wiley-Vch, 2003
e20394191
eBooks Universitas Indonesia Library
The essentials of drug metabolism vital to developing new therapeutic entities.
Information on the metabolism and disposition of candidate drugs is a critical part of all aspects of the drug discovery and development process. Drug metabolism, as practiced in the pharmaceutical industry today, is a complex, multidisciplinary field that requires knowledge...
Hoboken, New Jersey: John Wiley & Sons, 2008
e20395867
eBooks Universitas Indonesia Library
Sadee, Wolfgang, author
New York: John Wiley & Sons, 1980
615.7 SAD d
Buku Teks Universitas Indonesia Library
This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both pharmacology and pharmacokinetic aspects of enzyme inhibition. Additionally, the book covers the inhibition of drug metabolizing and disposition enzymes including transporters (mostly "bad" or "undesirable" enzyme inhibition) as well as the...
Hoboken: John Wiley & Sons, 2010
e20393914
eBooks Universitas Indonesia Library
Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing...
Hoboken: John Wiley & Sons, 2010
e20393919
eBooks Universitas Indonesia Library
This book gives an updated and expert overview of nuclear hormone receptors in drug metabolism and drug development and equips you with the interdisciplinary understanding of these receptors and how they can be regulated. Pharmaceutical researchers will find this extremely useful in developing drugs for cancer, heart disease, and diabetes...
Hoboken, New Jersey: John Wiley & Sons, 2009
e20394374
eBooks Universitas Indonesia Library
