Ditemukan 19 dokumen yang sesuai dengan query
The only reference on current methods to generate pharmacokinetic and safety profiles of drug candidates, as well as how they must be balanced against one other for the best selection of candidates for further development. Following a brief introduction to the necessities of filtering and risk assessment of potential new...
Weinheim, Germany: Wiley-VCH, 2009
e20394190
eBooks Universitas Indonesia Library
Arya, Dev P., author
This is the first book to provide a complete overview of recent advances in the field and explore their tremendous potential for drug discovery and rational drug design. With chapters written by one or more leading experts in their specialty areas, the book addresses the chemistry, biology, and toxicology of...
Hoboken, New Jersey: John Wiley & Sons, 2007
e20395834
eBooks Universitas Indonesia Library
This practice-oriented handbook surveys current knowledge on the prediction and prevention of adverse drug reactions related to off-target activity of small molecule drugs. It is unique in collating the current approaches into a single source, and includes several highly instructive case studies that may be used as guidelines on how...
Weinheim, Germany: Wiley-Vch, 2008
e20375710
eBooks Universitas Indonesia Library
Barrier, reservoir, target site, those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid membranes and of the various modes of drug-membrane interaction is therefore the prerequisite for a better understanding of drug action....
Weinheim, Germany: Wiley-Vch Verlag, 2002
e20393901
eBooks Universitas Indonesia Library
This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries,...
Weinheim, Germany: Wiley-VCH, 2008
e20395825
eBooks Universitas Indonesia Library
Lin, Guo-Qiang, editor
Presenting an overview of chiral drugs and their impact on the pharmaceutical industry, Chiral drugs : chemistry and biological action provides an integrated perspective of chiral drugs from concept, synthesis, and pharmaceutical properties. The book includes important chiral technologies and reviews of 200 chiral drugs that have either been approved...
Hoboken: John Wiley & Sons, 2011
e20376590
eBooks Universitas Indonesia Library
London: Pharmaceutical Press, 2012
R 615.19 HAN
Buku Referensi Universitas Indonesia Library
This unique reference source, edited by the world's most respected expert on molecular interaction field software, covers all relevant principles of the GRID force field and its applications in medicinal chemistry. Entire chapters on 3D-QSAR, pharmacophore searches, docking studies, metabolism predictions and protein selectivity studies, among others, offer a concise...
Weinheim, Germany: Wiley-VCH, 2006
e20394260
eBooks Universitas Indonesia Library
Computer-assisted techniques are well-integrated in modern drug discovery and used for the finding of new leads, the optimization of receptor or enzyme affinity, as well as of pharmacokinetic and physicochemical properties.
In this book an account is found of current strategies used in computer-assisted drug design. Important topics include progress in...
Weinheim, Germany: Wiley-Vch, 1997
e20377187
eBooks Universitas Indonesia Library
