Ditemukan 3 dokumen yang sesuai dengan query
Pustika Amalia Wahidiyat, author
Latar belakang: Thalassemia dan hemoglobinopati merupakan kelainan gen tunggal terbanyak di dunia, termasuk di Indonesia dengan frekuensi pembawa sifat thalassemia-~ 3-10% dan HbE 1-36%. Thalassemia-WIThE adalah bentuk heterozigot ganda paling sering ditemukan dengan gejala klinis bervariasi, dari asimtomatik sampai berat. Beberapa faktor pemodifikasi telah diketahui memengaruhi manifestasi klinis. Faktanya pasien...
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2009
D1765
UI - Disertasi Open Universitas Indonesia Library
Pustika Amalia Wahidiyat, author
ABSTRACT
Background: there are currently three iron chelator readily available for patients Indonesia; deferiprone/DFP (branded as Ferriprox), deferasirox/DFX (branded as Exjade) and deferoxamine/DFO (branded as Desferal). This study aims to determine which iron chelator is the most efficient in reducing cardiac and hepatic iron overload (measured by means of T2 MRI)....
Jakarta: University of Indonesia. Faculty of Medicine, 2018
JAK 3:2 (2017)
Artikel Jurnal Universitas Indonesia Library
Pustika Amalia Wahidiyat, author
ABSTRACT
Background: routine blood transfusion in transfusion-dependent-thalassemia (TDT) causes iron accumulation in various organ. Serum markers of iron overload, serum ferritin and transferrin saturation, are sensitive but not specific. MRI T2-star (T2*) is valuable for detecting iron level in organs. This study aimed to explore the degree of iron overload in...
Jakarta: University of Indonesia. Faculty of Medicine, 2018
610 UI-IJIM 50:3 (2018)
Artikel Jurnal Universitas Indonesia Library
