Ditemukan 7 dokumen yang sesuai dengan query
New Jersey: John Wiley & Sons, 2012
615.9 PRE
Buku Teks Universitas Indonesia Library
This book addresses all the current, up-to-date developments in this scientific discipline. Liver is the chief metabolizing site in the body, and thus, it is a major target organ for drug and chemical toxicity. Therefore, hepatotoxicity is an important endpoint in the safety evaluation of drugs and chemicals.
Contributions from leading...
Chichester, West Sussex, England: John Wiley & Sons, 2007
e20395854
eBooks Universitas Indonesia Library
This book the only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview of the entire sequence of operations involved in drug discovery and development from initial conceptualization to commercialization to clinicians and medical practitioners.
Volume 2 : drug development delves into the nitty-gritty details of optimizing the...
Hoboken, New Jersey: John Wiley & Sons, 2007
e20395858
eBooks Universitas Indonesia Library
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. The authors discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining...
Weinheim: Wiley-VCH, 2006
e20395921
eBooks Universitas Indonesia Library
This book contains case studies of the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil). Discusses the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer. Contains chapters on combinatorial chemistry, molecular biology-based drug discovery,...
Hoboken, New Jersey: Wiley-Interscience, 2006
e20395928
eBooks Universitas Indonesia Library
Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing...
Hoboken: John Wiley & Sons, 2010
e20393919
eBooks Universitas Indonesia Library
The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current methods and techniques. Each chapter was written by one or more leading experts in the...
Hoboken, New Jersey: Wiley-VCH, 2008
e20394504
eBooks Universitas Indonesia Library
