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Ditemukan 3 dokumen yang sesuai dengan query
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With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an important biological process that has not yet been covered in such depth in any other existing books on GPCRs. The international team of highly distinguished authors addresses in detail current models and concepts,...
Weinheim, Germany: Wiley-VCH, 2005
e20393932
eBooks  Universitas Indonesia Library
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G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a rational drug design. Based on recent examples from academia and the pharmaceutical...
Weinheim, Germany: Wiley-VCH, 2006
e20395916
eBooks  Universitas Indonesia Library
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Main question : G protein coupled receptors are involved in highly efficient and specific activation of signalling pathways. How do GPCR signalling complexes get assembled to generate such specificity? In order to answer this question, we need to understand how receptors and their signalling partners are synthesized, folded and quality-controlled...
Dordrecht: Springer, 2012
e20417317
eBooks  Universitas Indonesia Library