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Ditemukan 2 dokumen yang sesuai dengan query
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Theresia Thiofani, author
Sintesis Senyawa Antara 2-([4-okso-2-morfolin-1-ilmetil)kuinazolin-3- il]amino)benzonitril = Synthesis Of Intermediate Compound 2-([4-oxo-2-morpholin-1-ylmethyl)quinazolin-3- yl]amino)benzonitrile
Dipeptidyl peptidase-4 inhibitors (DPP-4) is an oral therapeutic agent used for treatment of type 2 diabetes that has proven to have a low risk of hypoglycemia and can be well tolerated. Non-selective inhibitory ability of DPP-4 enzyme causes several side effects such as alopecia, thrombocytopenia, splenomegaly, and etc. Quinazolinone analogs...
Depok: Fakultas Farmasi Universitas Indonesia, 2020
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UI - Skripsi (Membership)  Universitas Indonesia Library
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Syafura Az-Zahra, author
Uji Aktivitas Inhibitor Dipeptidil Peptidase-4, Anti-Inflamasi, dan Antioksidan 2-(Stiril)-N-(2-Siano) Benzil-Kuinazolinon dan Analognya Secara In Vitro = In Vitro Activity Test of Dipeptidyl Peptidase-4 Inhibitor, Anti-Inflammation, and Antioxidant 2-(Styril)-N-(2-Cyaano) Benzyl-Quinazolinone and Its Analogs
Diabetes melitus tipe 2 (DMT2) merupakan penyakit metabolik yang ditandai dengan hiperglikemia dalam keadaan puasa atau setelah pemberian glukosa selama tes toleransi glukosa oral. Di dalam tubuh terdapat enzim dipeptidil peptidase-4 (DPP-4) menyebabkan degradasi Glucagon Like Peptide-1 (GLP-1) dan Glucose-dependent Insulinotropic Polypeptide (GIP) sehingga mengurangi bioavailabilitas dan efek inkretin. Penyakit...
Depok: Fakultas Farmasi Universitas Indonesia, 2023
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UI - Skripsi Membership  Universitas Indonesia Library