Sintesis senyawa antibakteri turunan pirazol dan isoksazol dari kurkumin menggunakan nanokatalis cuo@sio2 serta uji bioaktivitas terhadap bakteri stphylococcus aureus dan escherichia coli = Syinthesis of antibacterial compounds pirazole and isoxazole derived from curcumin using cuo sio2 nanocatalyst and bioactivity test against staphylococcus aureus and escherichia coli bacteria