Efek implantasi sekretom, sel punca mesenkimal sumsum tulang xenogenik, BMP-2, granul hidroksiapatit, dan fiksasi mekanik terhadap defek luas tulang panjang tikus sprague dawley = The effect of secretome, xenogenic bone marrow-mesenchymal stem cell, BMP-2, hydroxyappatite granule with mechanical fixation to critical sized bone defect sprague dawley rat