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Pengantar ilmu penyakit darah / oleh C. Haanen ... [et al.]
Bandung: Binacipta, 1980
616.15 PEN
Buku Teks SO  Universitas Indonesia Library
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Lea Ratna Lestari
Korelasi lemak viseral dengan tekanan darah dan fungsi ginjal pada pekerja kantor dengan obesitas di Jakarta = Correlation of visceral fat with blood pressure and kidney function in obese office workers in Jakarta
"Latar Belakang: Prevalensi obesitas, hipertensi dan penyakit ginjal kronis (PGK) pada pekerja kantor di Jakarta cukup tinggi. Meningkatnya volume lemak viseral pada obesitas, khususnya obesitas sentral,  memiliki kemaknaan klinis yang lebih besar dalam memprediksi kejadian hipertensi dan PGK. Studi ini bertujuan untuk meneliti korelasi nilai lemak viseral tubuh dengan tekanan darah (TD) dan fungsi ginjal pada populasi pekerja kantor dengan obesitas di Jakarta.
Metode: Studi potong lintang dilakukan pada 101 pekerja kantor dengan obesitas di RSUPN Cipto Mangunkusumo Jakarta. Pengukuran volume lemak viseral menggunakan alat bioelectrical impedance analysis multifrekuensi SECA mBCA 525. TD diukur dengan tensimeter digital, fungsi ginjal dari hasil perhitungan estimasi laju filtrasi glomerulus (eLFG) berdasarkan nilai kreatinin serum.
Hasil: Subjek terbagi menjadi dua kelompok berdasarkan kategori lemak viseral. Sebanyak 91% subjek berada di dalam kelompok lemak viseral tidak normal, dimana didominasi perempuan serta rerata usia dan indeks massa tubuh lebih tinggi dibandingkan kelompok normal. Pada kelompok tersebut, 33,7% diantaranya memiliki TD sistolik ≥140 dan/ atau diastolik ≥90 mmHg, dan 18,5% memiliki eLFG <90 ml/menit/1,73 m2. Adanya korelasi positif antara nilai lemak viseral dengan tekanan darah sistolik (r =0,436, p =0,000) dan diastolik (r =0,306, p =0,002), serta korelasi negatif dengan eLFG (r =-0,284, p =0,004).
Kesimpulan: Terdapat korelasi yang bermakna antara lemak viseral dengan tekanan darah dan fungsi ginjal pada pekerja kantor dengan obesitas.
Background: The prevalence of obesity, hypertension and chronic kidney disease (CKD) among office workers in Jakarta is relatively high. Increased visceral fat in obesity, especially central obesity, has greater clinical significance in predicting the incidence of hypertension and CKD. This study aims to examine the correlation of visceral fat values with blood pressure (BP) and kidney function in office workers in an obese population in Jakarta.
Methods: A cross-sectional study was conducted on 101 office workers with obesity at Cipto Mangunkusumo General Hospital, Jakarta. Visceral fat volume was measured using a multi-frequency bioelectrical impedance analysis SECA mBCA 525. BP was measured with a digital tensimeter, and kidney function was taken from the estimated glomerular filtration rate (eGFR) calculation based on serum creatinine.
Results: Subjects were divided into two groups based on the category of visceral fat. About 91% of the subjects were in the abnormal visceral fat group, dominated by women, and the mean age and body mass index were higher than the normal group. In this group, 33.7% had systolic BP ≥140 and/or diastolic ≥90 mmHg, and 18.5% had an eGFR <90 ml/min/1.73 m2. There was a positive correlation between visceral fat values with systolic (r =0.436, p =0.000) and diastolic BP (r =0.306, p = 0.002) and a negative correlation with eGFR (r =-0.284, p =0.004).
Conclusion: There is a significant correlation between visceral fat and blood pressure and kidney function in office workers with obesity."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Bobby Anggara
Penilaian Analisis Gas Darah dan AaDO2 pada saat pertama kali masuk sebagai faktor prognostik pada pasien COVID-19 terkonfirmasi yang meninggal di RSUP Persahabatan = Arterial blood gas analysis and alveolar-arterial oxygen gradient as predictors of mortality in COVID-19 confirmed patients treated at Persahabatan Hospital, Jakarta
"Latar belakang: Mekanisme penyebab kematian COVID-19 adalah terjadinya hipoksemia dan ARDS. Salah satu komponen dalam penilaian ARDS adalah hasil Annalisis Gas Darah (AGD) dan nilai perbedaan tekanan parsial oksigen di arteri dan alveolus yang dikenal sebagai AaDO2. Peran nilai analisis gas darah dan AaDO2 pada luaran meninggal COVID-19 perlu di telaah lebih lanjut.
Metode penelitian: Analisis deskriptif kohort retrospektif terhadap pasien COVID-19 terkonfirmasi yang dirawat di RSUP Persahabatan secara consecutive sampling dari bulan maret sampai dengan agustus 2020. Kami meninjau 205 rekam medis pasien terkonfirmasi yang telah memenuhi kriteria inklusi.
Hasil: Median dan rentang nilai pH, PaCO2, PaO2, HCO3, BE, SaO2, FiO2, SpO2 adalah 7,41(7,01-7,54), 32,1(17,5-87,1), 73,9(22,7-343,7), 21(7,2-38,9), -3,8(-22,2-13,3), 94,9(33,5-99,9), 0,54(0,21-1,00), 95(33,5-99,9) secara berurutan. Terapi oksigen yang digunakan pasien adalah masker oksigen nonhirup ulang sebesar 37,56% diikuti dengan kanula hidung sebesar 32,20%, ventilator mekanis sebesar 16,59%, kanula hidung arus tin ggi sebesar 10,73%, masker sederhana sebesar 0,98% dan masker venturi sebesar 0,49%. Median nilai AaDO2 sebesar 272,58% (40,55-644,17). Derajat penyakit klinis terbanyak memiliki derajat klinis kritis sebesar 93,2%. Gangguan asam basa yang dialami pasien adalah 33,51% mengalami gangguan asam basa campuran, 22% mengalami gangguan asidosis metabolik tidak terkompensasi dan 25% pasien mengalami asidosis repiratorik terkompensasi. Terdapat korelasi parameter PaO2, BE, SaO2, FiO2, PAO2 dan AaDO2 dengan kejadian kematian pasien (p<0,05).
Background: The cause of death in COVID-19 is hypoxemia in acute respiratory distress syndrome (ARDS). This condition could be assessed through arterial blood gas analysis by determining the alveolar arterial oxygen gradient value (AaDO2). The role of arterial blood gas analysis and AaDO2 to predict mortality in COVID-19 is yet to be explored.
Methods: We performed observational retrospective cohort analysis of COVID-19 confirmed patients treated at Persahabatan Hospital, Jakarta, Indonesia. Subject by means of consecutive sampling were COVID-19 confirmed patients between March and August 2020. We reviewed the medical record of 205 patients whom meet the inclusion criteria.
Results: Median value and range of pH, PaCO2, PaO2, HCO3, BE, SaO2, FiO2, SpO2 were 7.41(7.01-7.54), 32.1(17.5-87.1), 73.9(22.7-343.7), 21(7.2-38.9), -3.8(-22.2-13.3), 94.9(33.5-99.9), 0.54(0.21-1.00) and 95(33.5-99.9). Most of the patients use non-rebreathing mask (37.56%), followed by nasal cannula (32.2%), mechanical ventilator (16.59%), high flow nasal cannula (10.73%), simple mask (0.98%) and venturi mask (0.49%). Median value of AaDO2 was 272.58 (40.55-644.17). Most of the patients were critically ill (93.2%). There were 33.51% patients presented with the mix acid base disorder, 22% with uncompensated metabolic acidosis disorder and 25% with compensated respiratory acidosis disorder. There was a correlatio"
Depok: Fakultas Kedokteran Universitas Indonesia, 2021
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
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Ariska Silviani
Korelasi kadar profil lipid darah dengan derajat keparahan dermatitis seboroik pada skalp = Correlation of blood lipid profile levels with the severity of scalp seborrheic dermatitis
"Dermatitis seboroik (DS) merupakan penyakit inflamasi kulit kronis pada area yang banyak mengandung kelenjar sebasea, terutama area skalp, yang ditandai plak eritematosa dan skuama. Lipid darah diduga dapat memengaruhi derajat keparahan DS. Penelitian sebelumnya di berbagai negara tentang kadar lipid darah pada pasien DS menunjukkan hasil yang bervariasi. Penelitian ini bertujuan untuk mendapatkan data kadar profil lipid darah pasien DS pada skalp serta melakukan analisis korelasi kadar profil lipid darah dengan derajat keparahan DS pada skalp. Penelitian ini merupakan penelitian deskriptif-analitik dengan desain potong-lintang. Tiga puluh pasien DS pada skalp usia 18–59 tahun yang memenuhi kriterian penerimaan dan penolakan direkrut dalam penelitian ini. Penilaian derajat keparahan penyakit menggunakan skor modifikasi Seborrheic Dermatitis Area Severity Index (SDASI) dan dilakukan pengukuran kadar lipid darah yang mencakup kadar trigliserida, kolesterol total, low-density lipoproteins (LDL), dan high-density lipoproteins(HDL). Median kadar trigliserida adalah 83 mg/dL, rerata kadar kolesterol total adalah 175,53 mg/dL, rerata kadar LDL adalah 114,77 mg/dL, dan median kadar HDL adalah 45,50 mg/dL. Berdasarkan analisis Pearson, tidak terdapat korelasi antara kadar trigliserida dengan derajat keparahan DS pada skalp (r=0,291; p=0,119). Terdapat korelasi positif kuat yang bermakna antara kadar kolesterol total dengan derajat keparahan DS pada skalp (r=0,860; p<0,001).Terdapat korelasi positif sangat kuat yang bermakna antara kadar LDL dengan derajat keparahan DS pada skalp (r=0,980; p<0,001). Tidak terdapat korelasi antara kadar HDL dengan derajat keparahan DS pada skalp (r=-0,068; p=0,723).
Seborrheic dermatitis (SD) is a chronic inflammatory skin disease in sebaceous glands rich area, especially the scalp area, which is characterized by erythematous plaques and scales. Blood lipids are thought to affect the severity of SD. Previous studies in various countries about blood lipid levels in SD patients showed varying results. This study aims to know the levels of blood lipid profile in patients suffering scalp SD, also to analyze its correlation with the severity of scalp SD. This is an analytic-descriptive cross-sectional study. Thirty scalp SD patients age 18–59 years old who meet all inclusion and exclusion criteria were recruited in this study. Assessment of the disease severity using modified Seborrheic Dermatitis Area Severity Index (SDASI) score and measurements of blood lipid levels which include triglycerides, total cholesterol, low-density lipoproteins (LDL), and high-density lipoproteins (HDL) levels were performed. Median triglyceride level was 83 mg/dL, mean total cholesterol level was 175.53 mg/dL, mean LDL level was 114.77 mg/dL, and median HDL was 45.50 mg/dL. Based on Pearson analysis, there was no correlations between triglyceride levels and scalp SD severity (r=0.291; p=0.119). There was a significant strong positive correlation between total cholesterol levels and scalp SD severity (r=0.860; p<0.001). There was a significant very strong positive correlation between LDL levels and scalp SD severity (r=0.980; p<0.001). There was no correlations between HDL levels and scalp SD severity (r=-0.068; p=0.723)."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Tambunan, Marihot
Perbedaan pola sirkadian tekanan darah pada pasien penyakit ginjal kronik pra dan pasca transplantasi ginjal di RSCM = The difference of circadian pattern of blood pressure in patients with chronic kidney disease before and after kidney transplantation in Cipto Mangunkusumo hospital
"[ABSTRAK
Pola sirkadian tekanan darah (TD) adalah gambaran TD 24 jam berupa kurva TD yang meningkat pada pagi hari, menurun pada siang / sore hari dan terendah pada malam hari / waktu tidur. 24 hours Ambulatory Blood Pressure Monitoring (24 hrs ABPM) merupakan alat pengukur TD yang lebih akurat dan dapat memperlihatkan pola sirkadian TD 24 jam. Turunnya TD 10 - 20% pada malam hari disebut dipper, jika turun < 10% disebut nondipper. Meningkatnya TD 24 jam dan nondipper merupakan faktor risiko morbiditas dan mortalitas kardiovaskular. Prevalensi hipertensi dan nondipper pada Penyakit Ginjal Kronik Stadium 5 dalam Terapi Dialisis (PGK 5D) masih sangat tinggi. Faktor utama penyebab hipertensi pada PGK 5D adalah menurunnya Laju Filtrasi Glomerulus (LFG) dan meningkatnya cairan ekstraselular. Transplantasi ginjal akan memperbaiki TD dan nondipper dengan membaiknya LFG, meningkatnya produksi urin dan menurunnya cairan ekstraseluler. Namun demikian satu bulan Pasca Transplantasi Ginjal kebutuhan dosis obat imunosupresan masih cukup tinggi yang dapat mengakibatkan hambatan penurunan TD.
Tujuan : Mengetahui perbedaan pola sirkadian TD, data dipper / nondipper dan rerata TD 24 jam pada pasien PGK Pra dan satu bulan Pasca Transplantasi Ginjal. Metode Penelitian : Studi Pre experimental dengan before and after design. Subjek penelitian pasien PGK 5D / Pra Transplantasi Ginjal berusia 18 ? 60 tahun, dilakukan di RSCM pada bulan Oktober sampai dengan Desember 2014. Jumlah subjek sebanyak 15 orang. Dilakukan pengumpulan urin 24 jam, pemeriksaan LFG, pengukuran TD 24 jam dengan 24 hrs ABPM, Pra dan satu bulan Pasca Transplantasi Ginjal. Analisis statistik dengan uji McNemar dan uji t dependen.
Hasil : Terdapat 12 subjek nondipper dan 3 subjek dipper pada pasien PGK Pra Transplantasi Ginjal. Satu bulan Pasca Transplantasi Ginjal seluruh subjek (15 orang) memperlihatkan keadaan nondipper. Uji McNemar tidak dapat dilakukan karena seluruh subjek PGK satu bulan Pasca Transplantasi Ginjal nondipper (homogen). Terdapat penurunan rerata TD sistolik 24 jam pasien PGK satu bulan Pasca Transplantasi Ginjal yang tidak signifikan (p > 0,05) dan penurunan rerata TD diastolik 24 jam yang signifikan (p < 0,05).
Simpulan : Belum terdapat perbaikan nondipper pada pasien satu bulan Pasca Transplantasi Ginjal. Terdapat penurunan rerata TD sistolik 24 jam yang tidak signifikan dan penurunan rerata TD diastolik 24 jam yang signifikan pada pasien satu bulan Pasca Transplantasi Ginjal.
ABSTRACT
The circadian pattern of blood pressure (BP) is a 24 hours blood
pressure (24hrs BP) curve which increases in the morning, decreases in the
afternoon/evening and the lowest state is at night/bedtime. 24 hrs Ambulatory
Blood Pressure Monitoring (ABPM) is a BP measuring device that is
accurate and can exhibit a circadian pattern of 24 hrs BP. The fall of BP 10-􀀃20%
at night is called as a dipper, while less than 10% is called as a nondipper. The
increasing of 24 hrs BP and nondipper are the risk factor for
cardiovascular morbidity and mortality. The prevalence of
hypertension and nondipper in Chronic Kidney Disease stage 5 on Dialysis
(CKD 5D) are still very high. The main factors causing hypertension in CKD 5D
are decreased Glomerular Filtration Rate (GFR) and increased extracellular
fluid. Kidney transplantation will improve BP and nondipper
by GFR improvement, increases urine production and decreases extracellular
fluid. However, one month after kidney transplantation, the dose
of immunosuppressant drugs is relatively high, which is an obstacle to decrease
BP.
Aim: To determine differences in the circadian pattern of BP, the data
of dipper and nondipper, and the mean of 24 hrs BP in CKD before, and one
month after kidney transplantation.
Methods: Design of the study is before and after design. Subjects of the study
were patients with CKD 5D before kidney transplantation, aged 18-60 years,
were conducted in Cipto Mangunkusumo Hospital during October to
December 2014. 15 subjects were included in the study. 24 hrs urine
collection, GFR, 24 hrs BP measurement with 24 hrs ABPM were recorded in all
subjects, before and one month after kidney transplantation. McNemar test and t
dependent test were used in statistical analysis.
Results: Before kidney transplantation, 12 of 15 subjects were nondippers while
the others 3 subjects were dippers. After kidney transplantation, all subjects (15
patients) were nondippers. McNemar test can not be used because all subjects one
month after kidney transplantation were nondippers (homogeneous). The
decreasing of the mean of 24 hrs systolic BP was found in all CKD one
month after kidney transplantation, but statistically not significant (p>0.05),
while decreasing of the mean of 24 hrs diastolic BP was statistically significant
(p<0.05).
Conclusion: There were still no improvement in nondipper patients
one month after kidney transplantation. There were a decrease in the mean of 24
hrs systolic BP but statistically not significant and a decrease in the mean of 24
hrs diastolic BP which is statistically significant in patients one month after
kidney􀀃transplantation.;Background: The circadian pattern of blood pressure (BP) is a 24 hours blood
pressure (24hrs BP) curve which increases in the morning, decreases in the
afternoon/evening and the lowest state is at night/bedtime. 24 hrs Ambulatory
Blood Pressure Monitoring (ABPM) is a BP measuring device that is
accurate and can exhibit a circadian pattern of 24 hrs BP. The fall of BP 10-􀀃20%
at night is called as a dipper, while less than 10% is called as a nondipper. The
increasing of 24 hrs BP and nondipper are the risk factor for
cardiovascular morbidity and mortality. The prevalence of
hypertension and nondipper in Chronic Kidney Disease stage 5 on Dialysis
(CKD 5D) are still very high. The main factors causing hypertension in CKD 5D
are decreased Glomerular Filtration Rate (GFR) and increased extracellular
fluid. Kidney transplantation will improve BP and nondipper
by GFR improvement, increases urine production and decreases extracellular
fluid. However, one month after kidney transplantation, the dose
of immunosuppressant drugs is relatively high, which is an obstacle to decrease
BP.
Aim: To determine differences in the circadian pattern of BP, the data
of dipper and nondipper, and the mean of 24 hrs BP in CKD before, and one
month after kidney transplantation.
Methods: Design of the study is before and after design. Subjects of the study
were patients with CKD 5D before kidney transplantation, aged 18-60 years,
were conducted in Cipto Mangunkusumo Hospital during October to
December 2014. 15 subjects were included in the study. 24 hrs urine
collection, GFR, 24 hrs BP measurement with 24 hrs ABPM were recorded in all
subjects, before and one month after kidney transplantation. McNemar test and t
dependent test were used in statistical analysis.
Results: Before kidney transplantation, 12 of 15 subjects were nondippers while
the others 3 subjects were dippers. After kidney transplantation, all subjects (15
patients) were nondippers. McNemar test can not be used because all subjects one
month after kidney transplantation were nondippers (homogeneous). The
decreasing of the mean of 24 hrs systolic BP was found in all CKD one
month after kidney transplantation, but statistically not significant (p>0.05),
while decreasing of the mean of 24 hrs diastolic BP was statistically significant
(p<0.05).
Conclusion: There were still no improvement in nondipper patients
one month after kidney transplantation. There were a decrease in the mean of 24
hrs systolic BP but statistically not significant and a decrease in the mean of 24
hrs diastolic BP which is statistically significant in patients one month after
kidney􀀃transplantation.;Background: The circadian pattern of blood pressure (BP) is a 24 hours blood
pressure (24hrs BP) curve which increases in the morning, decreases in the
afternoon/evening and the lowest state is at night/bedtime. 24 hrs Ambulatory
Blood Pressure Monitoring (ABPM) is a BP measuring device that is
accurate and can exhibit a circadian pattern of 24 hrs BP. The fall of BP 10-􀀃20%
at night is called as a dipper, while less than 10% is called as a nondipper. The
increasing of 24 hrs BP and nondipper are the risk factor for
cardiovascular morbidity and mortality. The prevalence of
hypertension and nondipper in Chronic Kidney Disease stage 5 on Dialysis
(CKD 5D) are still very high. The main factors causing hypertension in CKD 5D
are decreased Glomerular Filtration Rate (GFR) and increased extracellular
fluid. Kidney transplantation will improve BP and nondipper
by GFR improvement, increases urine production and decreases extracellular
fluid. However, one month after kidney transplantation, the dose
of immunosuppressant drugs is relatively high, which is an obstacle to decrease
BP.
Aim: To determine differences in the circadian pattern of BP, the data
of dipper and nondipper, and the mean of 24 hrs BP in CKD before, and one
month after kidney transplantation.
Methods: Design of the study is before and after design. Subjects of the study
were patients with CKD 5D before kidney transplantation, aged 18-60 years,
were conducted in Cipto Mangunkusumo Hospital during October to
December 2014. 15 subjects were included in the study. 24 hrs urine
collection, GFR, 24 hrs BP measurement with 24 hrs ABPM were recorded in all
subjects, before and one month after kidney transplantation. McNemar test and t
dependent test were used in statistical analysis.
Results: Before kidney transplantation, 12 of 15 subjects were nondippers while
the others 3 subjects were dippers. After kidney transplantation, all subjects (15
patients) were nondippers. McNemar test can not be used because all subjects one
month after kidney transplantation were nondippers (homogeneous). The
decreasing of the mean of 24 hrs systolic BP was found in all CKD one
month after kidney transplantation, but statistically not significant (p>0.05),
while decreasing of the mean of 24 hrs diastolic BP was statistically significant
(p<0.05).
Conclusion: There were still no improvement in nondipper patients
one month after kidney transplantation. There were a decrease in the mean of 24
hrs systolic BP but statistically not significant and a decrease in the mean of 24
hrs diastolic BP which is statistically significant in patients one month after
kidney􀀃transplantation.;Background: The circadian pattern of blood pressure (BP) is a 24 hours blood
pressure (24hrs BP) curve which increases in the morning, decreases in the
afternoon/evening and the lowest state is at night/bedtime. 24 hrs Ambulatory
Blood Pressure Monitoring (ABPM) is a BP measuring device that is
accurate and can exhibit a circadian pattern of 24 hrs BP. The fall of BP 10-􀀃20%
at night is called as a dipper, while less than 10% is called as a nondipper. The
increasing of 24 hrs BP and nondipper are the risk factor for
cardiovascular morbidity and mortality. The prevalence of
hypertension and nondipper in Chronic Kidney Disease stage 5 on Dialysis
(CKD 5D) are still very high. The main factors causing hypertension in CKD 5D
are decreased Glomerular Filtration Rate (GFR) and increased extracellular
fluid. Kidney transplantation will improve BP and nondipper
by GFR improvement, increases urine production and decreases extracellular
fluid. However, one month after kidney transplantation, the dose
of immunosuppressant drugs is relatively high, which is an obstacle to decrease
BP.
Aim: To determine differences in the circadian pattern of BP, the data
of dipper and nondipper, and the mean of 24 hrs BP in CKD before, and one
month after kidney transplantation.
Methods: Design of the study is before and after design. Subjects of the study
were patients with CKD 5D before kidney transplantation, aged 18-60 years,
were conducted in Cipto Mangunkusumo Hospital during October to
December 2014. 15 subjects were included in the study. 24 hrs urine
collection, GFR, 24 hrs BP measurement with 24 hrs ABPM were recorded in all
subjects, before and one month after kidney transplantation. McNemar test and t
dependent test were used in statistical analysis.
Results: Before kidney transplantation, 12 of 15 subjects were nondippers while
the others 3 subjects were dippers. After kidney transplantation, all subjects (15
patients) were nondippers. McNemar test can not be used because all subjects one
month after kidney transplantation were nondippers (homogeneous). The
decreasing of the mean of 24 hrs systolic BP was found in all CKD one
month after kidney transplantation, but statistically not significant (p>0.05),
while decreasing of the mean of 24 hrs diastolic BP was statistically significant
(p<0.05).
Conclusion: There were still no improvement in nondipper patients
one month after kidney transplantation. There were a decrease in the mean of 24
hrs systolic BP but statistically not significant and a decrease in the mean of 24
hrs diastolic BP which is statistically significant in patients one month after
kidney􀀃transplantation.;Background: The circadian pattern of blood pressure (BP) is a 24 hours blood
pressure (24hrs BP) curve which increases in the morning, decreases in the
afternoon/evening and the lowest state is at night/bedtime. 24 hrs Ambulatory
Blood Pressure Monitoring (ABPM) is a BP measuring device that is
accurate and can exhibit a circadian pattern of 24 hrs BP. The fall of BP 10-􀀃20%
at night is called as a dipper, while less than 10% is called as a nondipper. The
increasing of 24 hrs BP and nondipper are the risk factor for
cardiovascular morbidity and mortality. The prevalence of
hypertension and nondipper in Chronic Kidney Disease stage 5 on Dialysis
(CKD 5D) are still very high. The main factors causing hypertension in CKD 5D
are decreased Glomerular Filtration Rate (GFR) and increased extracellular
fluid. Kidney transplantation will improve BP and nondipper
by GFR improvement, increases urine production and decreases extracellular
fluid. However, one month after kidney transplantation, the dose
of immunosuppressant drugs is relatively high, which is an obstacle to decrease
BP.
Aim: To determine differences in the circadian pattern of BP, the data
of dipper and nondipper, and the mean of 24 hrs BP in CKD before, and one
month after kidney transplantation.
Methods: Design of the study is before and after design. Subjects of the study
were patients with CKD 5D before kidney transplantation, aged 18-60 years,
were conducted in Cipto Mangunkusumo Hospital during October to
December 2014. 15 subjects were included in the study. 24 hrs urine
collection, GFR, 24 hrs BP measurement with 24 hrs ABPM were recorded in all
subjects, before and one month after kidney transplantation. McNemar test and t
dependent test were used in statistical analysis.
Results: Before kidney transplantation, 12 of 15 subjects were nondippers while
the others 3 subjects were dippers. After kidney transplantation, all subjects (15
patients) were nondippers. McNemar test can not be used because all subjects one
month after kidney transplantation were nondippers (homogeneous). The
decreasing of the mean of 24 hrs systolic BP was found in all CKD one
month after kidney transplantation, but statistically not significant (p>0.05),
while decreasing of the mean of 24 hrs diastolic BP was statistically significant
(p<0.05).
Conclusion: There were still no improvement in nondipper patients
one month after kidney transplantation. There were a decrease in the mean of 24
hrs systolic BP but statistically not significant and a decrease in the mean of 24
hrs diastolic BP which is statistically significant in patients one month after
kidney􀀃transplantation., Background: The circadian pattern of blood pressure (BP) is a 24 hours blood
pressure (24hrs BP) curve which increases in the morning, decreases in the
afternoon/evening and the lowest state is at night/bedtime. 24 hrs Ambulatory
Blood Pressure Monitoring (ABPM) is a BP measuring device that is
accurate and can exhibit a circadian pattern of 24 hrs BP. The fall of BP 10-􀀃20%
at night is called as a dipper, while less than 10% is called as a nondipper. The
increasing of 24 hrs BP and nondipper are the risk factor for
cardiovascular morbidity and mortality. The prevalence of
hypertension and nondipper in Chronic Kidney Disease stage 5 on Dialysis
(CKD 5D) are still very high. The main factors causing hypertension in CKD 5D
are decreased Glomerular Filtration Rate (GFR) and increased extracellular
fluid. Kidney transplantation will improve BP and nondipper
by GFR improvement, increases urine production and decreases extracellular
fluid. However, one month after kidney transplantation, the dose
of immunosuppressant drugs is relatively high, which is an obstacle to decrease
BP.
Aim: To determine differences in the circadian pattern of BP, the data
of dipper and nondipper, and the mean of 24 hrs BP in CKD before, and one
month after kidney transplantation.
Methods: Design of the study is before and after design. Subjects of the study
were patients with CKD 5D before kidney transplantation, aged 18-60 years,
were conducted in Cipto Mangunkusumo Hospital during October to
December 2014. 15 subjects were included in the study. 24 hrs urine
collection, GFR, 24 hrs BP measurement with 24 hrs ABPM were recorded in all
subjects, before and one month after kidney transplantation. McNemar test and t
dependent test were used in statistical analysis.
Results: Before kidney transplantation, 12 of 15 subjects were nondippers while
the others 3 subjects were dippers. After kidney transplantation, all subjects (15
patients) were nondippers. McNemar test can not be used because all subjects one
month after kidney transplantation were nondippers (homogeneous). The
decreasing of the mean of 24 hrs systolic BP was found in all CKD one
month after kidney transplantation, but statistically not significant (p>0.05),
while decreasing of the mean of 24 hrs diastolic BP was statistically significant
(p<0.05).
Conclusion: There were still no improvement in nondipper patients
one month after kidney transplantation. There were a decrease in the mean of 24
hrs systolic BP but statistically not significant and a decrease in the mean of 24
hrs diastolic BP which is statistically significant in patients one month after
kidney􀀃transplantation.]"
2015
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Eliezer Sutopo
Faktor-faktor yang berhubungan dengan sindrom metabolik pada masyarakat di wilayah kerja Puskesmas Cimanuk dan Saketi, Kabupaten Pandeglang, Banten tahun 2017: analisis lanjut deteksi dini penyakit jantung dan pembuluh darah Kementerian Kesehatan Republik Indonesia = Factors associated with metabolic syndrome in communities of Cimanuk and Saketi Health Center working area Pandeglang Regency Banten 2017: advanced analysis of early detection of heart disease and blood vessels Ministry of Health of the Republic of Indonesia
"Faktor-Faktor Yang Berhubungan Dengan Sindrom Metabolik pada Masyarakat di Wilayah Kerja Puskesmas Cimanuk dan Saketi, Kabupaten Pandeglang, Banten Tahun 2017 Analisis Lanjut Deteksi Dini Penyakit Jantung dan Pembuluh Darah Kementerian Kesehatan Republik Indonesia Tahun 2017 rdquo; Skripsi ini bertujuan untuk mengetahui faktor-faktor yang berhubungan umur, jenis kelamin, pendidikan, pekerjaan, riwayat penyakit tidak menular dalam keluarga, Perilaku merokok, konsumsi buah dan sayur, aktivitas fisik, stress, dan Indeks Massa Tubuh dengan sindrom metabolik pada masyarakat di wilayah kerja Puskesmas Cimanuk dan Saketi, Kabupaten pandeglang, Banten tahun 2017. Penelitian ini bersifat deskriptif analitik dengan menggunakan desain Cross sectional. Penelitian dilaksanakan dari bulan Maret-Juni 2017 dengan menggunakan data dari deteksi dini Program Pencegahan dan Pengendalian Penyakit Jantung dan Pembuluh Darah Kementerian Kesehatan RI tahun 2017 dengan sampel sebanyak 359 sampel. Hasil penelitian menunjukkan sebesar 38,2 masyarakat di wilayah kerja Puskesmas Cimanuk dan Saketi, Kabupaten Pandenglang, Banten mengalami sindrom metabolik. Uji chi-square menunjukkan adanya hubungan signifikan secara statistik antara umur p value=0,001 , pendidikan p value=0,023 , pekerjaan p value=0,041 , dan Indeks Massa Tubuh p value=0,001 terhadap sindrom metabolik. Sedangkan melalui uji multivariat didapatkan variabel yang paling berpengaruh adalah indeks massa tubuh POR=0,334 . Melalui penelitian ini dapat memberikan informasi terutama masyarakat di Kecamatan Cimanuk dan Saketi, Kabupaten Pandeglang, Banten agar dapat menjaga kesehatan melalui pola hidup sehat, serta ikut serta dalam kegiatan Posbindu maupun Penyuluhan yang dilakukan oleh penyedia layanan kesehatan terkait.
Factors Associated with Metabolic Syndrome in Communities of Cimanuk and Saketi Health Center Working Area, Pandeglang Regency, Banten 2017 Advanced Analysis of Early Detection of Heart Disease and Blood Vessels Ministry of Health of the Republic of Indonesia 2017 This thesis aims to know the related factors age, sex, education, occupation, history of non communicable diseases in the family, smoking behavior, consumption of fruits and vegetables, physical activity, stress, and body mass index with metabolic syndrome in the community in the working area of puskesmas cimanuk and saketi, pandeglang district, banten in 2017. This study is analytical descriptive using cross sectional design. The study was conducted from March to June 2017 using data from the early detection of the program of prevention and control of heart and vein disease the Ministry of Health Republic of Indonesia in 2017 with a sample of 359 samples. The results showed that 38.2 of people in the working area of cimanuk and saketi health center, pandenglang district, banten had metabolic syndrome. Chi square test showed a statistically significant correlation between age p value 0.001 , education p value 0.023 , occupation p value 0.041 , and body mass index p value 0.001 against metabolic syndrome. While through multivariate test, the most influential variable is body mass index POR 0,334 . Through this research can provide information, especially the community in district cimanuk and saketi, pandeglang regency, banten in order to maintain health through healthy lifestyles, and participate in activities Posbindu and counseling conducted by health related providers. "
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2017
S68644
UI - Skripsi Membership  Universitas Indonesia Library
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Williams manual of hematology / Marshall A. Lichtman ... [et al.]
New York: McGraw-Hill Medical, 2011
616.15 WIL
Buku Teks SO  Universitas Indonesia Library
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Diah Nuraini Sulistyaningsih
Korelasi frekuensi kunjungan terhadap nilai tengah tekanan darah pasien pos pembinaan terpadu Posbindu penyakit tidak menular KDK FKUI Kayu Putih, Jakarta Timur = The correlation between frequency of visits to the median of blood pressure in patients with non communicable disease of community health post KDK FKUI Kayu Outih East Jakarta
"Penyakit tidak menular merupakan masalah yang masih menjadi perhatian nasional maupun global. Jika penyakit tidak menular tidak ditangani secara tepat, benar, dan berkelanjutan, akan berdampak pada pertumbuhan ekonomi nasional. Oleh karena itu, dikembangkan model pengendalian penyakit tidak menular melalui Pos Pembinaan Terpadu Posbindu penyakit tidak menular PTM untuk menyelesaikan masalah tersebut. Penelitian ini bertujuan untuk mengetahui korelasi antara frekuensi kunjungan Posbindu dengan nilai tengah tekanan darah sistolik dan diastolik. Pada penelitian ini, dilibatkan sebanyak 100 pengunjung Posbindu dengan frekuensi kunjungan antara 1-6 kali. Kemudian dilakukan uji statistik untuk mengetahui korelasi antara frekuensi kunjungan Posbindu dengan nilai tengah tekanan darah sistolik dan diastolik. Mayoritas pengunjung Posbindu adalah perempuan 80 dengan kelompok usia 46-65 tahun 48 . Dari 100 pengunjung, 39 overweight dan 20 memiliki hipertensi. Melalui uji korelasi Spearman, diketahui bahwa tidak terdapat korelasi yang bermakna antara frekuensi kunjungan dengan nilai tengah tekanan darah sistolik p = 0,302, r = 0,104 maupun diastolik p = 0,321, r = 0,100. Dari penelitian ini, dapat disimpulkan bahwa tidak terdapat korelasi antara frekuensi kunjungan dengan nilai tengah tekanan darah sistolik dan diastolik.
Non communicable diseases are still a national and global disease burden. If the diseases are not handled properly, correctly, and sustained, the diseases will have an impact on national economic growth. To resolve the issue, the government has developed a model of non communicable disease control through community health post. This study aimed to investigate the correlation between frequency of community health post visits to the median of systolic and diastolic blood pressure. About one hundred patients of community health post with the frequency of visits between 1 to 6 times were selected. From 100 patients, 80 were female with the age group of 45 65 years 48 . Furthermore, 39 patients were overweight and 20 had hypertension. Through the Spearman correlation analysis, it is known that there is no significant correlation between the frequency of visits to the median of systolic blood pressure p 0,302, r 0,104 and diastolic blood pressure p 0,321, r 0,100 . In conclusion, there is no correlation between the frequency of visits to the median of systolic and diastolic blood pressure."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
S70331
UI - Skripsi Membership  Universitas Indonesia Library
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Adi Priyana
Kualitas Konsentrat Trombosit, Kriopresipitat dan Darah Simpan Produksi LTD PMI DKI Jakarta
"Permasalahan
Jumlah penduduk di kota kota besar di Indonesia khususnya di Jakarta meningkat dengan pesat dari tahun ke tahun. Kepadatan lalu lintas yang meningkat cenderung meningkatkan angka kecelakaan lalu lintas. Akibatnya kebutuhan akan darah transfusi juga turut meningkat. Hal tersebut terbukti dari meningkatnya jumlah permintaan akan darah transfusi baik di Rumah Sakit Cipto Mangunkusumo (RSCM) maupun di Palang Merah Indonesia (PMI). Selain untuk mengatasi perdarahan akibat kecelakaan lalu lintas, banyak keadaan lain yang memerlukan darah seperti perdarahan pada persalinan dan operasi. Pada beberapa penyakit hanya diperlukan bagian tertentu dari darah, oleh karena itu dilakukan usaha pemisahan darah menjadi komponen-komponen darah seperti konsentrat sel darah merah, konsentrat trombosit, konsentrat leukosit dan plasma. Dengan memisahkan darah menjadi komponen-komponen darah, maka pemakaian darah dapat lebih efisien, karena 1 kantung darah donor dapat digunakan oleh beberapa penderita sesuai dengan kebutuhan.
Di Indonesia darah untuk transfusi disediakan dan diproses oleh Lembaga Transfusi Darah Palang Merah Indonesia DKI Jakarta (LTD PMI DKI Jakarta). Darah tersebut berasal dari para donor sukarela yang dengan ikhlas menyumbangkan darahnya demi kemanusiaan. Untuk memenuhi permintaan darah yang makin meningkat, LTD PMI berusaha meningkatkan jumlah produksinya dengan meningkatkan jumlah donor darah (tabel 1 dan 2).
Agar dapat melayani permintaan darah setiap waktu, LTD harus mempunyai persediaan darah yang disimpan. Darah simpan ini diperlukan pada saat kebutuhan meningkat, pada saat jumlah donor menurun seperti pada bulan puasa dan untuk memenuhi permintaan akan golongan darah yang langka.
Walaupun LTD PMI DKI Jakarta telah berhasil meningkatkan jumlah produksinya untuk memenuhi kebutuhan yang meningkat, tetapi kualitas produk PMI belum pernah diteliti. Padahal seperti pada pengobatan lain, keberhasilan pemberian darah atau komponennya tidak hanya tergantung pada kuantitasnya saja tetapi juga dari kualitasnya (1,2,3)."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 1989
T5396
UI - Tesis Membership  Universitas Indonesia Library
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Pathologie vasculaire du tube digestif : Physiopathologie, diagnostic et traitement / Jean-Pierre Chambon, Philippe Zerbib, André Khoury-Hélou
"La pathologie vasculaire digestive reste méconnue. Elle est rare, protéiforme, de traitement parfois complexe. Les auteurs ont eu l’opportunité de réunir dans le même établissement de santé plusieurs médecins de spécialités différentes : anesthésistes réanimateurs, gastro-entérologues, spécialistes en médecine vasculaire, nutritionnistes, radiologues, angéiologues et chirurgiens, qui se sont impliqués dans la prise en charge de la pathologie vasculaire digestive.
Ils ont réalisé un ouvrage collectif où ils font la synthèse, à la lumière de leur expérience, des dernières mises au point en pathologie vasculaire digestive. Sont abordés en particulier les ischémies intestinales aiguë et chronique, les colites et rectites ischémiques, les infarcissements veineux du grêle et du côlon, les anévrysmes et les dissections spontanées, les traumatismes ainsi que d’autres pathologies vasculaires plus rares pouvant toucher le tube digestif.
Le fait de travailler en équipe depuis plusieurs années donne aux auteurs une vision globale de ce sujet qui se traduit dans l’homogénéité de l’ouvrage. L’utilisation d’une illustration abondante et didactique facilite la lecture et la compréhension."
Paris: Springer, 2012
e20426677
eBooks  Universitas Indonesia Library
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