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Izati Rahmi
Uji diagnostik the neurological disorders depression inventory for epilepsy versi indonesia pada pasien epilepsi dewasa dengan gangguan depresi mayor = Diagnostic test study of indonesian version of the neurological disorders depression inventory for epilepsy in adult epilepsy patients with major depression disorders
"Latar belakang. Depresi merupakan salah satu gangguan psikiatri yang sering terjadi pada pasien epilepsi. Prevalensinya adalah 20-80%. Depresi bukan merupakan suatu pemeriksaan yang rutin dilakukan di poliklinik neurologi karena membutuhkan waktu yang cukup lama, sehingga banyak pasien yang tidak terdiagnosis dan akhirnya tidak terobati, untuk itu diperlukan pemeriksaan yang singkat. The Neurological Disorders Depression Inventory for-Epilepsi (NDDI-E) merupakan pemeriksaan skrining depresi yang terdiri dari 6-aitem.
Tujuan. Menentukan akurasi dan titik potong NDDI-E versi Indonesia sebagai skrining depresi pada pasien epilepsi dewasa.
Metode. Penelitian uji diagnostik yang dilakukan di poliklinik epilepsi RSCM. Pemeriksaan dilakukan pada semua pasien epilepsi yang memenuhi kriteria inklusi. Pasien mengisi sendiri formulir NDDI-E tanpa bantuan orang lain. Kemudian dilakukan pemeriksaan the International Neuropsychiatric Interview Mini ICD-10 (MINI-ICD10) sebagai standar baku.
Hasil. Dari 105 orang subyek penelitian terdapat 23 orang mengalami gangguan depresi mayor berdasarkan MINI-ICD 10. Didapatkan kurva Receiver Operating Characteristic (ROC) yang mendekati 100%, titik potong 11, dengan Sensitifitas 91,3% Spesifisitas 89% PPV 70% dan NPV 97,3%. Secara statistik NDDI-E versi Indonesia masuk dalam klasifikasi yang kuat, karena nilai Area Under the Curve (AUC) 97,5% dengan interval kepercayaan (95%CI 95%-99%).
Kesimpulan. NDDI-E versi Indonesia memiliki nilai akurasi yang tinggi untuk menentukan gangguan depresi mayor pada pasien epilepsi dewasa pada titik potong 11.
Background. Depression is a common psychiatric disorder in epilepsy. The prevalence is 20-80%. The depression is not a routinely assessed in neurology clinics, because the assestment takes a long time. So, many patients are under diagnosed and untreated. The Neurological Disorders Depression Inventory for-Epilepsy (NDDI-E) is a depression screening examination consist of only 6-aitem.
Purpose. To determine the accuracy and cut-off point of NDDI-E Indonesian version as a screening depression examination for adult epilepsy patients.
Method. Diagnostic test study was conducted at epilepsy clinic on RSCM. All the epilepsy patient who met the inclusion criteria was examined. The patient took the NDDI-E Indonesian version as a self assesment. Then there were assest with used the International Neuropsychiatric Interview Mini ICD-10 (MINI-ICD10) as a gold standar.
Results. From the 105 subjects, there were 23 people suffered from major depression by MINI-ICD10. Receiver Operating Characteristic (ROC) curve obtained which is close to 100%, cut-off point at 11, with Sensitivity 91.3% Specificity 89% PPV 70% and NPV of 97.3%. It was statistically classified as strong because the value of Area Under the Curve (AUC) is 97.5% with a confidence interval (95% CI 95% -99%).
Conclusion. NDDI-E Indonesian version has a high accuracy to determine major depressive disorder in adult epilepsy patients with the cut-off point at 11."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2013
T58561
UI - Tesis Membership  Universitas Indonesia Library
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Andira Larasari
Uji validitas, uji reliabilitas, dan uji diagnostik instrumen Generalized Anxiety Disorder-7 (GAD-7) versi bahasa Indonesia pada pasien epilepsi dewasa = Validity, reliability, and diagnostic tests of generalized Anxiety Disorder-7 (GAD-7) instrument Indonesian version in adult epilepsy patients
"ABSTRAK
Latar Belakang. Gangguan cemas menyeluruh (GCM) merupakan salah satu bentuk gangguan ansietas tersering pada populasi epilepsi yang dapat menurunkan kualitas hidup, sehingga deteksi dini sangatlah penting. Generalized Anxiety Disorder-7 (GAD-7) merupakan instrumen penapis GCM satu-satunya yang pernah divalidasi pada pasien epilepsi, yaitu di Korea dengan titik potong ≥7. Instrumen GAD-7 dapat dikerjakan pasien sendiri kurang dari 3 menit, sehingga cocok digunakan di poliklinik neurologi. Penelitian ini bertujuan untuk mendapatkan kuesioner GAD-7 versi bahasa Indonesia yang valid, reliabel dan akurat untuk menapis GCM pada pasien epilepsi dewasa.
Metode Penelitian. Penelitian dibagi menjadi 2 tahap. Tahap pertama meliputi adaptasi lintas budaya berdasarkan ketentuan World Health Organization (WHO), uji validitas isi berdasarkan penilaian pakar mengenai relevansi butir pertanyaan GAD-7 hasil adaptasi, dilanjutkan uji validitas interna, reliabilitas interna dan reliabilitas test-retest pada 30 pasien epilepsi yang memenuhi kriteria inklusi. Tahap kedua adalah uji diagnostik. Hasil GAD-7 dengan titik potong ≥7 dibandingkan dengan wawancara Mini International Neuropsychiatric Interview International Classification of Diseases-10 (MINI ICD-10) sebagai baku emas.
Hasil. Koefisien validitas isi berdasarkan metode Martuzua dari GAD-7 hasil adaptasi bahasa Indonesia adalah 0,847. Hasil uji validitas interna dengan korelasi Spearman didapatkan koefisien korelasi 0,648 hingga 0,800 (p<0,01). Uji reliabilitas konsistensi interna dengan Cronbach?s Alpha 0,867. Perbedaan nilai koefisien korelasi dan Cronbach?s Alpha antara pemeriksaan pertama dan retest menunjukkan reliabilitas test-retest yang baik. Dari 146 subyek uji diagnostik, prevalensi GCM hasil pemeriksaan MINI ICD-10 sebesar 16,4%. Dengan titik potong ≥7, GAD-7 memiliki sensitivitas 100% dan spesifisitas 84,4%.
Kesimpulan. Kuesioner GAD-7 versi Indonesia terbukti valid dan reliabel sehingga dapat digunakan untuk menapis GCM. Dengan titik potong ≥7, GAD-7 memiliki nilai akurasi yang tinggi untuk menapis GCM pada pasien epilepsi dewasa.ABSTRACT
Background. Generalized anxiety disorder (GAD) is one of the most common type among anxiety disorders in epilepsy population that can impaired patients quality of life. The Generalized Anxiety Disorder-7 (GAD-7) is a screening tool for detecting GAD that has been validated in epilepsy patients in Korea with cut-off point ≥7. The GAD-7 could be filled by the patients themselves in less than three minutes; hence, it is appropriate to be used in the neurology outpatient setting. The objective of this study is to obtain a valid, reliable, and accurate GAD-7 in Indonesian language as a screening tool of GAD in adult epilepsy patients.
Method. The study was conducted in two phases. The first phase included transcultural adaptation based on World Health Organization standards, content validity test based on expert consideration regarding the relevance of GAD-7 question items, followed by internal validity test, internal reliability test and test-retest in 30 epilepsy patients. The second phase was diagnostic test, in which, the GAD-7 with cut off point ≥7 will be compared with Mini International Neuropsychiatric Interview International Classification of Diseases-10 (MINI ICD-10) as the gold standard examination for diagnosing GAD.
Results. Content validity coefficient of GAD-7 adapted version based on Martuzua method was 0.847. Internal validity test with Spearman correlation obtained the correlation coefficient 0.648 to 0.800 (p< 0.01). Internal consistency reliability test with Cronbach?s Alpha was 0.867. The difference of correlation coefficient and Cronbach?s Alpha between the first and the retest showed good test-retest reliability. Out of 146 subjects of diagnostic test, the prevalence of GAD using MINI ICD-10 was 16.4%. With cut off point >7, GAD-7 had sensitivity 100% and specificity 84.4%.
Conclusion. The Indonesian version of the the GAD-7 was proven to be valid and reliable, also was found to be accurate as a screening tool for GAD in adult epilepsy patient with cut off point ≥7.;Background. Generalized anxiety disorder (GAD) is one of the most common type among anxiety disorders in epilepsy population that can impaired patients quality of life. The Generalized Anxiety Disorder-7 (GAD-7) is a screening tool for detecting GAD that has been validated in epilepsy patients in Korea with cut-off point ≥7. The GAD-7 could be filled by the patients themselves in less than three minutes; hence, it is appropriate to be used in the neurology outpatient setting. The objective of this study is to obtain a valid, reliable, and accurate GAD-7 in Indonesian language as a screening tool of GAD in adult epilepsy patients.
Method. The study was conducted in two phases. The first phase included transcultural adaptation based on World Health Organization standards, content validity test based on expert consideration regarding the relevance of GAD-7 question items, followed by internal validity test, internal reliability test and test-retest in 30 epilepsy patients. The second phase was diagnostic test, in which, the GAD-7 with cut off point ≥7 will be compared with Mini International Neuropsychiatric Interview International Classification of Diseases-10 (MINI ICD-10) as the gold standard examination for diagnosing GAD.
Results. Content validity coefficient of GAD-7 adapted version based on Martuzua method was 0.847. Internal validity test with Spearman correlation obtained the correlation coefficient 0.648 to 0.800 (p< 0.01). Internal consistency reliability test with Cronbach?s Alpha was 0.867. The difference of correlation coefficient and Cronbach?s Alpha between the first and the retest showed good test-retest reliability. Out of 146 subjects of diagnostic test, the prevalence of GAD using MINI ICD-10 was 16.4%. With cut off point >7, GAD-7 had sensitivity 100% and specificity 84.4%.
Conclusion. The Indonesian version of the the GAD-7 was proven to be valid and reliable, also was found to be accurate as a screening tool for GAD in adult epilepsy patient with cut off point ≥7.;Background. Generalized anxiety disorder (GAD) is one of the most common type among anxiety disorders in epilepsy population that can impaired patients quality of life. The Generalized Anxiety Disorder-7 (GAD-7) is a screening tool for detecting GAD that has been validated in epilepsy patients in Korea with cut-off point ≥7. The GAD-7 could be filled by the patients themselves in less than three minutes; hence, it is appropriate to be used in the neurology outpatient setting. The objective of this study is to obtain a valid, reliable, and accurate GAD-7 in Indonesian language as a screening tool of GAD in adult epilepsy patients.
Method. The study was conducted in two phases. The first phase included transcultural adaptation based on World Health Organization standards, content validity test based on expert consideration regarding the relevance of GAD-7 question items, followed by internal validity test, internal reliability test and test-retest in 30 epilepsy patients. The second phase was diagnostic test, in which, the GAD-7 with cut off point ≥7 will be compared with Mini International Neuropsychiatric Interview International Classification of Diseases-10 (MINI ICD-10) as the gold standard examination for diagnosing GAD.
Results. Content validity coefficient of GAD-7 adapted version based on Martuzua method was 0.847. Internal validity test with Spearman correlation obtained the correlation coefficient 0.648 to 0.800 (p< 0.01). Internal consistency reliability test with Cronbach?s Alpha was 0.867. The difference of correlation coefficient and Cronbach?s Alpha between the first and the retest showed good test-retest reliability. Out of 146 subjects of diagnostic test, the prevalence of GAD using MINI ICD-10 was 16.4%. With cut off point >7, GAD-7 had sensitivity 100% and specificity 84.4%.
Conclusion. The Indonesian version of the the GAD-7 was proven to be valid and reliable, also was found to be accurate as a screening tool for GAD in adult epilepsy patient with cut off point ≥7.;Background. Generalized anxiety disorder (GAD) is one of the most common type among anxiety disorders in epilepsy population that can impaired patients quality of life. The Generalized Anxiety Disorder-7 (GAD-7) is a screening tool for detecting GAD that has been validated in epilepsy patients in Korea with cut-off point ≥7. The GAD-7 could be filled by the patients themselves in less than three minutes; hence, it is appropriate to be used in the neurology outpatient setting. The objective of this study is to obtain a valid, reliable, and accurate GAD-7 in Indonesian language as a screening tool of GAD in adult epilepsy patients.
Method. The study was conducted in two phases. The first phase included transcultural adaptation based on World Health Organization standards, content validity test based on expert consideration regarding the relevance of GAD-7 question items, followed by internal validity test, internal reliability test and test-retest in 30 epilepsy patients. The second phase was diagnostic test, in which, the GAD-7 with cut off point ≥7 will be compared with Mini International Neuropsychiatric Interview International Classification of Diseases-10 (MINI ICD-10) as the gold standard examination for diagnosing GAD.
Results. Content validity coefficient of GAD-7 adapted version based on Martuzua method was 0.847. Internal validity test with Spearman correlation obtained the correlation coefficient 0.648 to 0.800 (p< 0.01). Internal consistency reliability test with Cronbach?s Alpha was 0.867. The difference of correlation coefficient and Cronbach?s Alpha between the first and the retest showed good test-retest reliability. Out of 146 subjects of diagnostic test, the prevalence of GAD using MINI ICD-10 was 16.4%. With cut off point >7, GAD-7 had sensitivity 100% and specificity 84.4%.
Conclusion. The Indonesian version of the the GAD-7 was proven to be valid and reliable, also was found to be accurate as a screening tool for GAD in adult epilepsy patient with cut off point ≥7."
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
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Lubna Muhammad Qadri
Reaksi simpang pada penggunaan oae pasien epilepsi menggunakan kuesioner liverpool adverse events profile versi bahasa Indonesia (uji validitas dan reliabilitas) = Adverse events of antiepileptic drugs in patients with epilepsy using the indonesian version of liverpool adverse events profile validity and reliability study
"Latar belakang : Reaksi simpang yang terjadi akibat penggunaan OAE berpengaruh terhadap kualitas hidup pasien epilepsi. Angka kejadian reaksi simpang akibat penggunaan OAE dilaporkan mencapai 80%. Sampai saat ini belum didapatkan studi atau instrumen yang valid dalam menilai reaksi simpang pada penggunaan OAE di Indonesia. Tujuan dari studi ini adalah melakukan validasi terhadap kuesioner Liverpool Adverse Events Profile (LAEP) versi bahasa Indonesia dan mendapatkan prevalensi reaksi simpang serta faktor yang berpengaruh.
Metode penelitian : Dilakukan studi observasional potong lintang pada pasien epilepsi dengan dosis OAE yang stabil di poliklinik epilepsi rumah sakit Cipto Mangunkusumo. Kuesioner diterjemahkan dari versi bahasa Inggris ke bahasa Indonesia dan dilakukan penerjemahan kembali ke bahasa aslinya untuk menilai ketepatan dari bahasa. Validitas dan reliabilitas diuji dengan menggunakan koefisien korelasi Spearman dan cronbach's alpha. Faktor yang dianalisis adalah durasi epilepsi, onset epilepsi, frekuensi bangkitan, tipe epilepsi, etiologi epilepsi, sindrom epilepsi, jumlah OAE, durasi OAE dan komorbiditas.
Hasil : Didapatkan 19 variabel pertanyaan yang valid dengan rentang koefisien korelasi 0,465 sampai 0,690. Cronbach?s alpha 0,846. Prevalensi reaksi simpang pada pasien epilepsi yaitu 91%. Reaksi simpang yang sering terjadi adalah kelelahan (67,8%), mengantuk (66,7%), gangguan daya ingat (62,2%) dan kesulitan berkonsentrasi (56,7%). Variabel klinis yang berpengaruh terhadap kejadian reaksi simpang yaitu politerapi (p=0.022).
Kesimpulan : Kuesioner Liverpool Adverse Events Profile versi bahasa Indonesia merupakan instrumen yang valid dan reliabel dalam menilai reaksi simpang pada penggunaan OAE pada pasien epilepsi. Politerapi merupakan faktor yang berpengaruh terhadap kejadian reaksi simpang.
Background : Adverse effects (AE) of antiepileptic drugs (AEDs) affect the quality of life of patients with epilepsy. The prevalence of AE of AEDs in patients with epilepsy is up to 80%. There are no studies nor validated instruments in measuring AE of AEDs in patients with epilepsy in Indonesia. This study aimed to validate the Indonesian version of The Liverpool Adverse Events Profile (LAEP) also to determine the prevalence of AE of AEDs in patients with epilepsy and related factors.
Methods : An observational cross-sectional study was carried out on epilepsy outpatients clinic in Cipto Mangunkusumo Hospital. Patient treated with a stable dose of AED were enrolled. The questionnaire was translated from the English version into Indonesian version and then was back-translated to examine its accuracy. The validity and reliability was tested by Spearman correlation coefficient and cronbach?s alpha. The Indonesian version of LAEP was selfadministered by the patient. The analyzed factors consisted of epilepsy duration, onset of epilepsy, seizure frequency, type of epilepsy, etiology and epilepsy syndrome, number of AEDs, AEDs duration and comorbidity.
Results : All of the 19 variable of questions were valid, with range of correlation coefficient from 0.465 to 0.690. The cronbach?s alpha was 0.846. Ninety patients were enrolled. The prevalence of AE of AEDs in patients with epilepsy was 91%. The most common AE were tiredness (67.8%), sleepiness (66.7%), memory problems (62.2%) and difficulty in concentrating (56.7%). Clinical variables that influenced the AE was polytherapy.
Conclusion : The Indonesian version of the Liverpool Adverse Events Profile is a valid and reliable instrument in assessing AE of AEDs in patients with epilepsy. Almost all of the patients in this study experienced an AE. Polytherapy was the related factors of AE of AEDs."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Ainun Intan Pradipta
Hubungan Gangguan Psikologis (Depresi, Ansietas dan Stres) dengan Kualitas Hidup pada Pasien Kanker: Telaah Literatur = The Relationship between Psychological Disorders (Depression, Anxiety and Stress) and Quality of Life in Cancer Patients: A Literature Review
"Kanker merupakan penyakit kronik yang menjadi penyebab kematian utama kedua di dunia. Dampak kanker dapat mempengaruhi fisik dan psikologis yang berpengaruh pada nilai kualitas hidup pasien kanker. Penulisan ini bertujuan untuk mengidentifikasi kekuatan hubungan antara gangguan psikologis (depresi, ansietas dan stres) dengan kualitas hidup pada pasien kanker. Metode dalam penulisan ini ialah telaah literatur dengan menggunakan prinsip Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Penelusuran jurnal dilakukan melalui database Pubmed, Clinical Key, Wiley Online Library, Sciencedirect, SAGE journals, dan Google Scholar. Analisis bias artikel dilakukan oleh dua reviewer dengan menggunakan The Joanna Briggs Institute Critical Appraisal Checklist. Hasil analisa pada enam belas jurnal didapatkan mayoritas pasien kanker mengalami depresi, ansietas dan stres serta mengalami penurunan kualitas hidup. Terdapat hubungan yang signikan antara depresi, ansietas dan stres dengan kualitas hidup pada pasien kanker.
Cancer is a chronic disease that is the second leading cause of death in the world. The impact of cancer can affect the physical and psychological factors that affect the quality of life of cancer patients. This article discusses the strenght of the relationship between psychological disorders (depression, anxiety, and stress) with quality of life in cancer patients. The method in this article is a literature review using the principles of Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Journals traced through the Pubmed, Clinical Key, Wiley Online Library, Sciencedirect, SAGE journals, and Google Scholar databases. The article bias analysis was assessed by two reviewers using The Joanna Briggs Institute Critical Appraisal Checklist. The results from analysis the journals obtained by patients experienced an increase in depression, anxiety, and stress and had decreased quality of life. There is a significant relationship between depression, anxiety, and stress with the quality of life in cancer patients."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2020
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UI - Skripsi Membership  Universitas Indonesia Library
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Merlyn Meta Astari
Penapisan Gejala Kecemasan dan Depresi pada Anak dengan Penyakit Ginjal Kronik (Kortisol sebagai Biomarker dan Kuesioner Screen for Anxiety and Related Disorders, Children Depression Inventory = Screening For Anxiety And Depression Symptoms In Children With Chronic Kidney Disease (Cortisol As A Biomarker And Screen Questionnaire For Anxiety And Related Disorders, Children Depression Inventory)
"Latar belakang: Anak dengan penyakit ginjal kronik (PGK) memiliki tantangan risiko gangguan cemas dan depresi yang besar karena stres fisis dan psikologis yang dialami. Kadar kortisol meningkat pada kondisi stres. Metode: Penelitian potong lintang ini melibatkan 91 anak dan remaja usia 8- 18 tahun dengan PGK di Rumah Sakit Cipto Mangunkusumo (RSCM). Gangguan psikososial melalui pengisian kuesioner screen for anxiety and related disorders dan children depression inventory. Kadar kortisol saliva diperiksa melalui pemeriksaan ELISA. Hasil: Prevalens gejala kecemasan pada stadium 1-3 sebesar 38,6% dan stadium 4-5 sebesar 40,4%. Prevalens gejala depresi pada stadium 1-3 sebesar 29,5% dan stadium 4-5 sebesar 38,3%. Median kadar kortisol pada anak dengan PGK yang mengalami gejala depresi 4,48 µg/dL tidak bermakna secara statistik dibandingkan yang tidak 3,85 µg/dL. Median kadar kortisol pada anak dengan PGK yang mengalami gejala kecemasan 4,57 µg/dL tidak bermakna secara statistik dibandingkan yang tidak 3,87 µg/dL. Median kortisol pada stadium 1-3 dan stadium 4-5 terhadap CDI tidak bermakna secara statistik. Median kortisol pada stadium 1-3 terhadap SCARED tidak bermakna secara stastistik, tetapi bermakna pada stadium 4-5 dengan p=0,034. Kesimpulan: Kortisol saliva pada PGK stadium 4-5 terdapat perbedaan bermakna antara yang mengalami gejala kecemasan dan tidak.
Objective: Children with chronic kidney disease (CKD) have a higher risk of anxiety and depression due to the physical and psychological stress. Cortisol levels increase under stressful conditions. Methods: This cross-sectional study involved 91 children and adolescents aged 8-18 years with CKD at Cipto Mangunkusumo Hospital. Psychosocial disorders through filling out screen for the anxiety and related disorders and children depression inventory questionnaires. Salivary cortisol levels were checked via ELISA. Results: The prevalence of anxiety symptoms in stages 1-3 was 38.6% and stages 4-5 was 40.4%. Prevalence of depressive symptoms in stages 1-3 was 29.4% and stages 4-5 was 38.3%. Median cortisol level in children with CKD who experienced depression symptoms was 4.48 µg/dL which was not statistically significant compared to 3.85 µg/dL for those who did not and who experienced anxiety symptoms was 4.57 µg/dL which was not statistically significant compared to 3.87 µg/dL for those who did not. Median cortisol at stages 1-3 and stages 4-5 for CDI was not statistically significant. Median cortisol at stages 1-3 of SCARED was not statistically significant, but was significant at stages 4-5 with p=0.034. Conclusion: There is a significant difference in stage 4-5 CKD who experienced anxiety symptoms and those who did not."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Dery Abdurrachim Iskandar
Gambaran interpersonal dependency pada orang dengan gangguan depresi mayor = The Description of Interpersonal Dependency of Person of Major Depression
"Ditinjau dari pendekatan Model kognitif, secara umum orang dengan Gangguan Depresi Mayor mengalami lima buah simtom Depresi yaitu simtom afektif, simtom, simtom kognitif, simtom motivasional, simtom fisik, dan simtom Behavioral. Model kognitif juga mengungkapkan tingginya kemungkinan terjadinya dependency pada orang dengan gangguan depresi sebagai salah satu bentuk nyata simtom behavioral Depresi Tingginya kemungkinan orang dengan gangguan depresi untuk mengalami dependency cenderung meningkatkan kemungkinan seseorang mengalami interpersonal dependency, yaitu sebuah bentuk ketergantungan yang dialami oleh seseorang dengan menjadikan orang lain sebagai objek ketergantungan tersebut.
Metode penelitian yang digunakan adalah metode kualitatif dengan pendekatan wawancara yang dilengkapi oleh metode observasi. Populasinya adalah orang-orang yang telah didiagnosis depresi mayor oleh psikolog maupun psikiater. Pemilihan sampel dilakukan dengan menggunakan theory based/operation construct sampling, di mana sampel dipilih dengan kriteria tertentu, berdasarkan teori atau konstruk operasional depresi yang termuat dalam DSM IV TR.
Diperoleh beragam gambaran interpersonal dependency pada orang dengan gangguan depresi yang dikelompokan dalam empat dimensi, yaitu kognitif, motivasional, afektif, dan behavioral di mana ditemukan peranan yang lebih dominan pada dimensi kognitif dan afektif. Selain itu diperoleh juga faktor-faktor ekstrinsik pada orang dengan gangguan depresi mayor berupa dalam proses terjadinya interpersonal dependency pada orang dengan gangguan depresi Mayor ,berupa peranan pola asuh orang tua.
Being analyze from The Cognitive Model approach, people who has major depression disorder are generally deliver through five depression symptoms. Those symptoms are affective symptom, cognitive symptom, motivational symptom, physical symptom and behavioral symptom. The Cognitive Model also elaborates the high possibility of dependency that could happen to people who has depression disorder as a frank appearance of behavioral symptom. This high possibility of dependency experienced by the ones who have major depression disorder tends to risen the possibility of interpersonal dependency, a form of dependency happened to certain people by making someone else as the object of the dependency.
This research process was using qualitative method with interview approach and observation method. The population of this research was those people diagnosed having major depression disorder by psychologist and or psychiatrist. The samples has chosen by using the theory based/operation construct sampling, where those samples picked out with certain criteria, based on the theories or depression operational construct stated in DSM IV TR.
During this research, various interpersonal dependency appearances are found in person who has diagnosed with major depression disorder, which could be classified to four dimensions: cognitive, motivational, affective and behavioral. We can also find the dimensions that have more dominant and stronger influence, which are cognitive dimension and affective dimension. Moreover, external factors could also be found occur to person with major depression disorder along with the forming of the interpersonal dependency, like parenting pattern role."
Depok: Fakultas Psikologi Universitas Indonesia, 2008
S-Pdf
UI - Skripsi Open  Universitas Indonesia Library
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Evans, Dwight L.
The physician's guide to depression and bipolar disorders
New York: McGraw-Hill, Medical Publishing Division, 2006
616.895 EVA p
Buku Teks  Universitas Indonesia Library
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Ercila Rizky Rolliana
Karakteristik Hormon Reproduksi dan Gangguan Menstruasi pada Wanita dengan Epilepsi di Rumah Sakit Umum Pusat Nasional dr. Cipto Mangunkusumo = The Characteristics of Reproductive Hormones and Menstrual Disorders in Women with Epilepsy at National Central General Hospital dr. Cipto Mangunkusumo
"Latar belakang: Hampir 50% epilepsi adalah wanita terjadi pada usia reproduksi 15-49 tahun. Banyak penelitian menyebutkan bahwa terdapat interaksi antara epilepsi dengan hormon reproduksi wanita. Epilepsi temporolimbik dapat mengganggu regulasi aksis hipothalamus- hipofisis-ovarium (HHO) sehingga mengganggu hormon reproduksi dan pada akhirnya menyebabkan gangguan menstruasi. Oleh karena itu dilakukan penelitian yang bertujuan untuk mengetahui perubahan hormon reproduksi yang terjadi pada wanita dengan epilepsis. Pada penelitian ini juga akan dilakukan klasifikasi gangguan menstruasi pada wanita dengan epilepsi berdasarkan kriteria The International Federation of Gynecology and Obstetrics (FIGO), dimana kriteria ini merupakan kriteria baru untuk mendefinisikan perdarahan uterus abnormal.
Metode penelitian: Penelitian ini dilakukan dengan studi potong lintang (cross sectional) untuk mengetahui karakteristik hormon reproduksi dan gangguan menstruasi pada wanita dengan epilepsi di RSUPN Cipto Mangunkusumo pada September hingga Desember 2021. Data primer dan sekunder diperoleh dari rekam medis dan electronic health record (EHR) pada pasien wanita dengan epilepsi dan wanita tanpa epilepsi yang berobat ke RSUPN Cipto Mangunkusumo. Analisis data yang digunakan adalah bivariat Chi Square dan Mann Whitney. Hasil: Pada penelitian ini diperoleh 67 subjek wanita dengan epilepsi dan 50 subjek wanita tanpa epilepsi dengan rata-rata usia wanita dengan epilepsi 29,27  9,26 tahun. Onset terjadinya epilepsi adalah 18,57  9,857 tahun dengan usia menarche adalah 12,85  1,317 tahun. Onset epilepsi setelah menarche banyak terjadi sekitar 70,1%. Epilepsi lobus temporal merupakan sindrom epilepsi terbanyak sekitar 70,8%, dengan sisi kanan terbanyak sekitar 46,8%. Peningkatan hormon reproduksi khususnya hormon luteinizing hormon (LH) 10,1 (0,1-100,3) mIU/mL (p: 0,008) dan hormon estradiol 71,2 (0-3350) pg/mL didapatkan pada wanita dengan epilepsi dibandingkan dengan wanita tanpa epilepsi. Gangguan pada volume darah mentruasi didapatkan pada wanita dengan epilepsi lobus temporal dibandingkan dengan lobus ekstratemporal RR 4,255 (1,188-15,231), dengan nilai p: 0,022.
Kesimpulan: Peningkatan hormon LH dan estradiol pada wanita dengan epilepsi berhubungan dengan bangkitan epileptik yang mengganggu regulasi aksis hipothalamus- hipofisis-ovarium sehingga mengganggu hormon reproduksi.
Background : Approximately 50% of epilepsy occurs in women with the reproductive age of 15-49 years. Many studies said that there is an interaction between epilepsy and female reproductive hormones. Temporolimbic epilepsy can interfere the regulation of the hypothalamic-pituitary-ovarian (HPO) axis so that it interferes reproductive hormones and ultimately causes menstrual disorders. Therefore, this study aimed to determine the changes in reproductive hormones that occur in women with epilepsy. This study will also classify menstrual disorders in women with epilepsy based on the criteria of The International Federation of Gynecology and Obstetrics (FIGO), where this criterion is a new criterion for defining abnormal uterine bleeding.
Method : This study was conducted with a cross sectional study to determine the characteristics of reproductive hormones and menstrual disorders in women with epilepsy at Cipto Mangunkusumo General Hospital from September to December 2021. Primary and secondary data were obtained from medical records and electronic health records (EHR) from women with epilepsy and women without epilepsy who seek treatment at Cipto Mangunkusumo General Hospital. Analysis of the data used Chi Square and Mann Whitney bivariate.
Result : In this study, there were 67 female subjects with epilepsy and 50 female subjects without epilepsy with the average age of women with epilepsy is 29,27  9,26 years. The onset of epilepsy was 18,57  9,857 years with the age of menarche is 12,85  1,317 years. The onset of epilepsy after menarche is mostly about 70.1%. Temporal lobe epilepsy is the most common epilepsy syndrome around 70.8%, with the right side being the most common around 46.8%. Increased reproductive hormones, especially luteinizing hormone (LH) 10.1 (0.1- 100.3) mIU/mL (p: 0.008) and estradiol hormone 71.2 (0-3350) pg/mL were found in women with epilepsy compared to women without epilepsy. Disorders of menstrual blood volume were found in women with temporal lobe epilepsy compared with extratemporal lobe epilepsy RR 4.255 (1.188-15.231), with p value: 0.022.
Conclusion : Elevated LH and estradiol hormones in women with epilepsy are associated with epileptic seizures that disrupt the regulation of the hypothalamic-pituitary-ovarian axis, thereby disrupting reproductive hormones."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
cover
Purwaningsih
Uji Kesahihan Dan Keandalan Kuesioner Abberant Behavior Checklist-Community 2017 Versi Bahasa Indonesia pada Anak dan Remaja dengan Gangguan Spektrum Autisme = Validity and Reliability Study of the Indonesian Version of the Abberant Behavior Checklist-Community 2017 Questionnaire for Children and Adolescents with Autism Spectrum Disorders
"Latar Belakang: Perilaku abberant sering terdapat pada pasien GSA. Salah satu kuesioner yang bisa digunakan untuk menilai perilaku abberant adalah kuesioner ABC-C 2017. Kuesioner ABC-C 2017 mengukur 5 domain perilaku abberant (iritabilitas, penarikan diri secara sosial, perilaku stereotipik, hiperaktivitas/ ketidakpatuhan dan pola bicara yang tidak tepat) pada anak dan remaja dengan diagnosis GSA, saat ini belum ada versi Bahasa Indonesia.
Metode: Penelitian ini menggunakan desain potong lintang untuk menilai kesahihan dan keandalan kuesioner ABC-C 2017 versi Bahasa Indonesia. Kesahihan isi dihitung menggunakan Content Validity Index for Items (I-CVI) dan Content Validity Index for Scales (S-CVI). Uji keandalan konsistensi internal dihitung menggunakan Cronbach alpha. Penelitian ini juga menilai proporsi perilaku abberant berdasarkan 5 domain kuesioner ABC-C 2017 versi Bahasa Indonesia, pada anak dan remaja dengan GSA di Poliklinik Jiwa Anak dan Remaja RSCM.
Hasil: Hasil analisis menunjukkan nilai I-CVI dan S-CVI kuesioner ABC-C 2017 versi Bahasa Indonesia sebesar 0,917, sehingga kesahihan isi kuesioner ini dinilai baik. Hasil keandalan konsistensi internal baik sampai excellent dengan nilai Cronbach’s alpha untuk masing-masing domain iritabilitas 0,938; penarikan diri secara sosial 0,936; perilaku stereotipik 0,930; hiperaktivitas, ketidakpatuhan 0,949 dan domain pola bicara yang tidak tepat 0,869. Proporsi perilaku abberant berdasarkan penilaian 5 domain kuesioner ABC-C 2017 versi Bahasa Indonesia, pada anak dan remaja dengan GSA di Poliklinik Jiwa Anak dan Remaja RSCM, didapatkan hasil, domain iritabilitas derajat ringan sebesar 70,6%; penarikan diri secara sosial derajat ringan 72,5%; perilaku stereotipik 100% derajat ringan; hiperaktivitas/ketidakpatuhan derajat sedang 47,1%, dan pola bicara yang tidak tepat 100% derajat ringan. Proporsi perilaku abberant berdasarkan usia dan jenis kelamin juga didominasi derajat ringan, kecuali domain hiperaktivitas/ketidakpatuhan derajat sedang. Tidak didapatkan perbedaan yang bermakna secara statistik, proporsi perilaku abberant berdasarkan usia dan jenis kelamin anak.
Kesimpulan: Kuesioner ABC-C 2017 versi Bahasa Indonesia dapat dipakai di Indonesia untuk penelitian selanjutnya, mendeteksi 5 domain perilaku abberant pada pasien GSA dan sebagai modul pendidikan bagi tenaga kesehatan.
Background: Abberant behavior is often found in ASD patients. One of the questionnaires that can be used to assess abusive behavior is the 2017 ABC-C questionnaire. The 2017 ABC-C questionnaire measures 5 domains of abberant behavior (irritability, social withdrawal, stereotypic behavior, hyperactivity/non-compliance and inappropriate speech patterns) in children. and adolescents with a diagnosis of ASD, currently there is no Indonesian version.
Methods: This study used a cross-sectional design to assess the validity and reliability of the Indonesian version of the 2017 ABC-C questionnaire. Content validity was calculated using the Content Validity Index for Items (I-CVI) and the Content Validity Index for Scales (S-CVI). Internal consistency reliability test was calculated using Cronbach alpha. This study also assessed the proportion of abusive behavior based on the 5 domains of the Indonesian version of the 2017 ABC-C questionnaire, in children and adolescents with ASD at the Children and Adolescent Mental Polyclinic RSCM.
Results: The results of the analysis show that the I-CVI and S-CVI scores of the 2017 ABC-C Indonesian version of the questionnaire are 0.917, so the validity of the contents of this questionnaire is considered good. The results of the reliability of internal consistency are good to excellent with Cronbach's alpha value for each irritability domain 0.938; social withdrawal 0.936; stereotypic behavior 0.930; hyperactivity, non-compliance 0.949 and inappropriate speech pattern domain 0.869. The proportion of abnormal behavior based on the assessment of the 5 domains of the 2017 ABC-C questionnaire in Indonesian version, in children and adolescents with ASD at the Child and Adolescent Mental Polyclinic RSCM, the results obtained, the domain of mild irritability was 70.6%; mild social withdrawal 72.5%; 100% mild stereotypic behavior; moderate degree of hyperactivity/non-compliance is 47.1%, and inappropriate speech is 100% mild. The proportion of abberant behavior based on age and gender was also dominated by mild degrees, except for the moderate degree of hyperactivity/non-compliance domain. There was no statistically significant difference, the proportion of abusive behavior based on the age and sex of the child.
Conclusion: The Indonesian version of the ABC-C 2017 Questionnaire can be used in Indonesia for further research, detecting 5 domains of abnormal behavior in ASD patients and as an education module for health workers."
Depok: Fakultas Kedokteran Universitas Indonesia, 2022
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
cover
Rosenthal, M. Sara
Women & depression : a sane approach to mood disorders
Los Angeles: Lowell House, 2000
616.58 ROS w (1)
Buku Teks  Universitas Indonesia Library
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