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Yayuk Setyowati
"Karya ilmiah akhir ini memberikan gambaran penerapan Model Konservasi Levine pada asuhan keperawatan pada bayi dengan risiko kerusakan integritas kulit dan pencapaian kompetensi sebagai spesialis keperawatan anak. Trophicognosis risiko kerusakan integritas kulit menurut Levine merupakan gangguan pada integritas struktur. Intervensi keperawatan dilakukan untuk mengatasi masalah integritas struktur tersebut dengan memperhatikan pula konservasi energi, konservasi integritas personal dan konservasi integritas sosial. Intervensi dilakukan dengan menerapkan aspek perawatan kulit dan cara memposisikan yang benar. Evaluasi yang dilakukan dengan mengkaji respon organismik bayi, menunjukkan bahwa belum semua bayi mampu mencapai wholeness yang ditandai dengan cedera pada nares, namun sudah mengalami perbaikan. Perawat memegang peranan yang sangat penting dalam pencegahan cedera pada nares yaitu pemilihan alat yang tepat, pemantauan dan pemenuhan kenyamanan bayi sehingga bayi tidak banyak bergerak dan mempercepat proses penyapihan continuous positive airway pressure (CPAP).

This Final Assignment gave an overview about the application of Levine's Conservation Model in nursing care of baby with risk of skin integrity breakdown and competency achievement as a pediatric nurse specialist. According to Levine, trophicognosis of skin integrity breakdown was the structure integrity impaiment. Nursing interventions was undertaken to solve structure integrity problem, and also energy conservation, personal conservation and social conservation. Nursing interventions applied the skin care aspetcs and positioning. Evaluation had been done by evaluate the organismic responses of the baby, showed that not all the baby got wholenes, was marked by nares injury, but getting better. Nurse had the crucial role to prevent nares injury, that to choise the appropriate tool, monitored ang gave baby’s comfort so the baby did not much to move and weaned the continuous positive airway pressure (CPAP) as soon as possible."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2014
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Ira Rahmawati
"Bayi prematur menghadapi banyak tantangan ketidakseimbangan cairan untuk bertahan di lingkungan ekstrauterin, sehingga membutuhkan pendekatan asuhan keperawatan yang komprehensif. Studi kasus ini menggambarkan proses keperawatan menggunakan model Konservasi Levine untuk merawat lima bayi prematur dengan ancaman keseimbangan cairan. Pengkajian mengidentifikasi triphocognosis meliputi risiko kekurangan volume cairan dan masalah cairan lainnya. Perawat anak merawat sesuai kompetensi, seperti pemantauan kesesuaian cairan masuk dan kebutuhan, pengurangan jumlah insensible water loss, blood management, dan peningkatan kemampuan minum melalui mulut. Intervensi membantu bayi prematur dan keluarga berhasil beradaptasi untuk mencapai wholeness. Penerapan model ini menyediakan pengalaman asuhan keperawatan yang komprehensif sebagai referensi untuk kasus serupa selanjutnya.

Preterm infants faces many challenges of fluid imbalance for survive in the extrauterine environment. It needs comprehensive nursing care approach. This study describes a nursing process using Levine’s Conservation model to care five preterm infants with threat to fluids imbalance. The assessments identified triphocognosis including risk of deficient fluid volume and other related problems. Pediatric nurse care according to competencies, such as monitoring the suitability of fluid intake and requirement, reducing the amount of insensible water loss, blood management, and increased oral feeding ability. The interventions helped the preterm infant and family adapt successfully to achieve wholeness. This application of model provides a comprehensive nursing care experience as reference for future similar cases."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2014
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Febriyanti
"Penulisan karya ilmiah akhir ini bertujuan untuk memberikan gambaran penerapan teori Model Konservasi pada bayi dengan kebutuhan asuhan perkembangan. Bayi berat lahir rendah (BBLR) membutuhkan adaptasi yang luar biasa agar dapat mempertahankan kelansungan hidupnya, oleh sebab itu dibutuhkan perawatan NICU. Namun ternyata dampak dari perawatan NICU yang lama mengakibatkan tingginya angka kesakitan dan disabilitas pada BBLR kedepannya. Oleh sebab itu intervensi dini harus sudah diberikan sejak awal bayi mulai dirawat melalui asuhan perkembangan. Asuhan perkembangan adalah segala upaya yang dilakukan dalam rangka memberikan dukungan fisik, psiko dan sosial kepada bayi berat lahir rendah dengan cara memodifikasi lingkungan agar dapat mempromosikan pertumbuhan dan perkembangannya. Salah satu intervensi dini yang dapat memperbaiki kekurangan stimulasi yang membangun untuk meningkatkan pertumbuhan dan perkembangan adalah stimulasi taktil kinestetik yang dilakukan oleh ibu.

This scientific final assignment is intended to describe the application of the theory of Conservation Model in infants with developmental care needs. Low birth weight infants needs a great effort to adapt and survive, therefore need neonatal intensive care unit (NICU). But it turns out the impac to fthe old NICU care resulting in high morbidity and disability. Therefore,early intervention should have been given since the beginning of the baby was admitted through developmental care. Developmental care is all the efforts made in order to facilitate and support the physical, social and psycho of low birth weight infant through modifications to the environment to be able to promote the growth and development of low birth weight infant. One of the early intervention that can correct the lack of stimulation to promote growth and development is a tactile kinestetic stimulation by the mother.
"
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2014
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Zubaidah
"Intoleransi minum merupakan masalah yang umum terjadi pada bayi prematur Tujuan penulisan Karya Ilmiah Akhir ini adalah memberikan gambaran penerapan Model Konservasi Levine pada bayi prematur dengan intoleransi minum dan gambaran pelaksanaan Praktik Residensi Keperawatan Anak Model Konservasi Levine berfokus pada peningkatan adaptasi melalui prinsip konservasi untuk mencapai integritas diri Penerapan Model Konservasi Levine tertuang dalam lima kasus terpilih Pada lima kasus terpilih tersebut ditemukan masalah gangguan pemenuhan kebutuhan nutrisi yang disebabkan oleh intoleransi minum Adapun masalah keperawatan lainnya adalah bersihan jalan napas tidak efektif gangguan pola napas gangguan termoregulasi risiko infeksi risiko gangguan perkembangan dan gangguan proses keluarga Masalah masalah tersebut dapat memperberat intoleransi minum dan menghambat proses pemulihan pada bayi prematur Asuhan keperawatan pada kasus terpilih diberikan oleh residen dengan melaksanakan perannya sebagai pemberi asuhan pendidik konsultan koordinator pengambil keputusan etik legal dan sebagai peneliti.

Feeding intolerance is a common problem in premature infants The purpose of this Final Scientific Work is to describe the application of Levine Conservation Model in preterm infants with feeding intolerance and the implementation of Pediatric Nursing Residency Practice Levine Conservation Model focuses on the adaptation improvement through conservation principles to achieve wholeness Levine Conservation Model was implemented in five selected cases In the five selected cases there was a nutritional intake problem caused by feeding intolerance The other problems were ineffective airway clearance ineffective breathing pattern ineffective thermoregulation risk for infection risk for developmental disorder and altered family process These problems can aggravate the feeding intolerance and inhibit the healing process of premature infants The nursing care to selected cases was given by the resident by implementing the roles as a caregiver an educator a consultant a coordinator an ethical and legal decision maker and a researcher"
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2013
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Tyagita Widya Sari
"Prematuritas merupakan salah satu penyebab terbesar morbiditas dan mortalitas bayi termasuk kematian neonatal. Penelitian ini bertujuan mengetahui besar hubungan prematuritas dengan kematian neonatal di Indonesia setelah seluruh variabel confounding (umur ibu, urutan kelahiran, jarak kelahiran, komplikasi kehamilan, komplikasi persalinan, tingkat pendidikan ibu, pekerjaan ibu, status ekonomi ibu, frekuensi ANC, komponen ANC 5T plus, penolong persalinan, tempat persalinan, jenis persalinan, dan wilayah tempat tinggal ibu) dikendalikan dan mengetahui besar PAR (Population Attributtable Risk) prematuritas terhadap kematian neonatal di Indonesia tahun 2010. Desain studi penelitian ini adalah kasus kontrol (1:4) dengan analisis multivariat regresi logistik ganda menggunakan data sekunder Riskesdas 2010. Jumlah sampel dalam penelitian ini adalah 120 kasus dan 480 kontrol. Hasil penelitian menunjukkan bahwa besar hubungan prematuritas dengan kematian neonatal setelah dikendalikan variabel confounding (komplikasi kehamilan, komplikasi persalinan, frekuensi ANC) yaitu OR sebesar 9,31 (95% CI : 4,63-18,70) dan PAR sebesar 19,96%. Untuk menurunkan kematian neonatal, diharapkan pemerintah dan masyarakat dapat berperan aktif dalam penurunan dan penanggulangan prematuritas sedini mungkin dengan peningkatan pelayanan antenatal.

Prematurity is one of the biggest main cause of morbidity and mortality of infant including the neonatal death. Aims of this research are to know how big the relationship between prematurity and neonatal death in Indonesia after all variables of confounding (age of mother, turn of birth, gap of birth, complication of pregnancy, complication of labor, mother’s education level, mother's job, mother's economic status, frequency of ANC, component of ANC 5T plus, labor helper, place of labor, kind of labor and mother’s region) have been controlled and to know how big the PAR (Population Attributtable Risk) of prematurity and neonatal death in Indonesia on 2010. The design of this research is case control (1:4) with multiple logistic regression to multivariate analysis using secondary data of Riskesdas 2010. The number of sample in this research is 120 cases and 480 controls. The result of this research shows the strong relation between prematurity and neonatal death after controlled by variables of confounding (complication of pregnancy, complication of labor, frequency of ANC) is OR as 9,31 (95% CI : 4,63-18,70) and PAR as 19,66%. To decrease the neonatal death, hopefully the government and public will actively support in decreasing and preventing the prematurity by improving the effectiveness of ANC.
"
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2014
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UI - Tesis Membership  Universitas Indonesia Library
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Francisca Shanti Kusumaningsih
"Bayi kurang bulan yang dirawat di rumah sakit seringkali mengalami nyeri yang disebabkan oleh prosedur diagnostik dan terapeutik. Tujuan dari studi kasus ini adalah memberikan gambaran aplikasi Model Konservasi Levine pada bayi kurang bulan dengan masalah nyeri. Model Konservasi Levine berfokus pada peningkatan adaptasi melalui prinsip konservasi untuk mencapai wholeness. Metode penelitian ini adalah studi kasus. Lima bayi kurang bulan yang mengalami masalah nyeri akut dirawat dengan pendekatan proses keperawatan berdasarkan teori Model Konservasi Levine. Masalah keperawatan lain yang ditemukan adalah pemenuhan nutrisi kurang dari keutuhan tubuh, risiko volume cairan kurang dari kebutuhan tubuh, risiko infeksi, ikterik neonaturum, gangguan pertumbuhan dan perkembangan risiko gangguan perlekatan orang tua dan bayi. Masalah-masalah tersebut dapat memperberat rasa nyeri dan menghambat proses adaptasi bayi kurang bulan dalam mencapai integritas diri.

Preterm infants who is hospitalized, experience pain frequently that caused by diagnostic and procedure treatment. This study aim to describe the application of Levine’s Conservation Model in preterm infants who experienced pain. Levine's Conservation Model focuses on improving adaptation through conservation principles to achieve wholeness. This research method is case study with nursing process approach. Levine’s Conservation Model applied in five selected cases that have problem acute pain. The other nursing problems are nutrition less than body requirements, risk for deficient fluid volume, risk of infection, neonaturum icteric, impaired growth and development, risk of attachment disorder between parents and babies. All of the problems can aggravate pain and inhibit the process of adaptation in preterm infant to reaches wholeness."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2014
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Nurhayati
"[ABSTRAK
Bayi prematur dapat mengalami hambatan kenaikan berat badan yang disebabkan oleh usia gestasi, penyakit penyerta, dan pengalaman nyeri atau stres. Hambatan kenaikan berat badan dapat diatasi dengan asuhan keperawatan yang tepat dalam pemenuhan kebutuhan nutrisi pada bayi prematur. Asuhan keperawatan dengan Model Konservasi Levine telah digunakan pada aplikasi praktik residensi di Ruang Neonatus Rumah Sakit Cipto Mangunkusumo dalam menganalisis kenaikan berat badan bayi prematur pada lima kasus terpilih mulai dari Bulan Maret-Mei tahun 2015. Analisis kasus didapatkan dari tahap pengkajian, tropikognosis, hipotesis, intervensi, dan evaluasi. Tropikognosis yang telah teridentifikasi yaitu risiko gangguan pemenuhan kebutuhan nutrisi. Intervensi telah dilakukan berdasarkan prinsip konservasi dan hasil evaluasinya yaitu bayi prematur mengalami kenaikan berat badan dengan konservasi energi. Kenaikan berat badan pada bayi prematur menunjukkan keberhasilan dari penerapan asuhan keperawatan berbasis Model Konservasi Levine.

ABSTRACT
The preterm infant can has an obstacle of increasing weight which is caused by gestational age, health problems which followed and pain/ stress experience. The obstacle of increasing weight can be handled with giving nursing care in proper nutrition needs. Nursing care with Levine?s Conservation Model has been applied in residence practice application in neonates wards Cipto Mangunkusumo hospital to analyze increasing weight of preterm infant in five selected cases start from March until May 2015. Case analyze is founded from assessment, trophicognosis, hypothesis, intervention, and evaluation. Trophicognosis which identified was disturbance risk in fullfil nutrition needs. Intervention were done based on conservation principle and the result of evaluation that preterm infant has increasing weight with energy conservation. Increasing weight in preterm infant showed a successful application of nursing care based on Levine?s Conservation Model. ;The preterm infant can has an obstacle of increasing weight which is caused by gestational age, health problems which followed and pain/ stress experience. The obstacle of increasing weight can be handled with giving nursing care in proper nutrition needs. Nursing care with Levine?s Conservation Model has been applied in residence practice application in neonates wards Cipto Mangunkusumo hospital to analyze increasing weight of preterm infant in five selected cases start from March until May 2015. Case analyze is founded from assessment, trophicognosis, hypothesis, intervention, and evaluation. Trophicognosis which identified was disturbance risk in fullfil nutrition needs. Intervention were done based on conservation principle and the result of evaluation that preterm infant has increasing weight with energy conservation. Increasing weight in preterm infant showed a successful application of nursing care based on Levine?s Conservation Model. , The preterm infant can has an obstacle of increasing weight which is caused by gestational age, health problems which followed and pain/ stress experience. The obstacle of increasing weight can be handled with giving nursing care in proper nutrition needs. Nursing care with Levine’s Conservation Model has been applied in residence practice application in neonates wards Cipto Mangunkusumo hospital to analyze increasing weight of preterm infant in five selected cases start from March until May 2015. Case analyze is founded from assessment, trophicognosis, hypothesis, intervention, and evaluation. Trophicognosis which identified was disturbance risk in fullfil nutrition needs. Intervention were done based on conservation principle and the result of evaluation that preterm infant has increasing weight with energy conservation. Increasing weight in preterm infant showed a successful application of nursing care based on Levine’s Conservation Model. ]"
Fakultas Ilmu Keperawatan Universitas Indonesia, 2015
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Anafrin Yugistyowati
"Penulisan karya ilmiah akhir ini bertujuan untuk mengaplikasikan teori Konservasi pada pemenuhan kebutuhan psikologis orang tua dengan bayi prematur. Pemenuhan kebutuhan psikologis orang tua dapat dilakukan melalui komunikasi terapeutik, pendampingan keluarga dan pemberian pendidikan kesehatan, memfasilitasi ikatan dan kelekatan orang tua-bayi, perencanaan pulang, asuhan berpusat pada keluarga, serta pendekatan asuhan perkembangan. Pemenuhan kebutuhan psikologis dapat membantu orang tua dalam proses adaptasi dalam pencapaian konservasi, yaitu konservasi melalui integritas personal sosial untuk mengoptimalkan peran orang tua dalam meningkatkan tumbuh kembang bayi prematur. Selama memberikan asuhan keperawatan, orang tua menunjukkan kondisi psikologis yang stabil, komunikasi dan kontak fisik dengan bayinya, pengetahuan dan keterampilan orang tua meningkat, serta adanya keterlibatan dalam perawatan bayi di RS

This study aims to apply Conservation theory to fulfill psychological needs of parents with premature infants. The fulfillment of psychological needs can be done through therapeutic communication, family counseling and provision of health education, facilitating the bonding and parents-infant attachment, discharge planning, family centered-care, as well as developmental care approach. The fulfillment of psychological needs help parents in the process of adaptation to achieve conservation, in this case the conservation of social-personal integrity to optimize the role of parents in improving the growth and development of premature infants. During the nursing care, parents showed a stable psychological condition, communication and physical contact with the baby, the increase in parenting knowledge and skills, as well as involvement in the infant care in the hospital"
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2013
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Sirait, Neni Ampi Juwita
"Infeksi adalah invasi mikroorganisme ke dalam tubuh Istilah sepsis digunakan untuk menggambarkan respon sistemik neonatus terhadap infeksi Kelahiran prematur merupakan faktor risiko yang berhubungan signifikan dengan kejadian sepsis Tujuan karya ilmiah ini adalah memberi gambaran aplikasi Model Konservasi Levine pada bayi prematur dengan masalah risiko infeksi Asuhan keperawatan pada kasus kelolaan tersangka sepsis neonatorum awitan dini SNAD menggunakan 4 prinsip konservasi Empat dari 5 bayi mampu beradaptasi dengan lingkungan ekstrauteri penyakit dan pengobatan sehingga tercapai suatu keutuhan diri wholeness Perawat profesional perlu memahami pola klinis bayi prematur yang berisiko mengalami sepsis dan dapat memberikan asuhan keperawatan yang tepat dan cepat Kata Kunci Bayi prematur Sepsis Keperawatan dan Model Konservasi Levine.

Infection is the invasion of microorganisms into the body The term sepsis is often used to describe the neonatal systemic response to infection Preterm birth is a significant risk factor associated with the incidence of sepsis The purpose of this final scientific report is illustrates the application of Levine rsquo s Conservation Model in preterm infants with infection risk issues Nursing care in the management preterm infant in the diagnosis with suspected early onset neonatal sepsis EOS used four conservation principles Four of five neonates were capable to adapt to extrauterine environment disease and treatment in order to reach wholeness Professional nurse have to understand the clinical pattern of preterm infants sepsis experience and provide an accurate nursing care fastly."
2013
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Esa Mannassa Resti
"[ABSTRAK
Latar belakang: Persalinan prematur sekarang ini menjadi tantangan dibidang
obstetri. Ini terlihat dari tingginya angka prematur di dunia. Dua hal yang harus
diperhatikan dalam kehamilan prematur yaitu kontraksi dan pemberian kortikosteroid
untuk pematangan paru, maka dibutuhkan suatu penanganan dengan menggunakan
obat tokolitik. Saat ini telah banyak digunakan terbutalin sulfat yang merupakan
golongan agonis beta dan juga nifedipine yang merupakan golongan penyekat kanal
kalsium. Namun penggunaan agonis beta menyebabkan efek yang kurang baik pada
ibu seperti takikardi, dispnoe dan ansietas sehingga penggunaannya sekarang mulai
terbatas. Tujuan: Tesis ini bertujuan mengetahui perbandingan efektifitas nifedipine
oral dibandingkan dengan terbutalin sulfat sebagai tokolitik dalam kehamilan
prematur. Metode: Penelitian ini merupakan uji klinis randomisasi tanpa penyamaran
pada ibu hamil prematur di kurang dari 34 minggu di RSUPN Cipto mangunkusumo.
Hasil: dari 60 subyek yang diikutsertakan dengan consecutive sampling, didapatkan
56 subyek (93,3%) hilang kontraksi dengan rincian 27 subyek (90,0%) pada
kelompok nifedipin dan 29 subyek (96,7%) pada kelompok terbutalin (p=0,61).
Kelompok yang diberikan nifedipin hilang kontraksi dengan median waktu 1,25
(0,67-2,00) jam sementara kelompok yang diberikan terbutalin hilang kontraksi lebih
cepat dengan median waktu 0,50 (0,50-1,50) jam (p<0,001). Tidak ada perbedaan efek samping yang ditemukan pada kedua kelompok. Simpulan: Nifedipin dan terbutalin memiliki efektifitas yang sama pada kehamilan prematur.

ABSTRACT
Background: Preterm labour is considered as one of problems frequently
encountered in obstetric and ginecologic department. To date, the incidence of
prematurity is still high worldwide. Two things should be noted: uterine contraction
and corticosteroid for lung maturity of the baby. Thus, a tocolytic agent may be useful
in these circumstances. To date, terbutaline sulfate is widely used as it is known as
beta agonist. Beside, nifedine, a calcium channel blocker, is also widely accepted. The
use of beta agonist might contribute several adverse events related to the mother,
including tachycardia, dispnea, and anxiety. Some physicians have begun to restrict
its use. Objective: This study aimed to compare the efficacy of slow release
nifedipine and terbutaline sulfate injection as a tocolytic agent for preterm labour.
Methods: This is a randomized clinical trial unblinding. Subjects were pregnant
women with prematurity (below 34 weeks of gestational age) at Cipto
Mangunkusumo hospital. Results: From a total of 60 subjects, 56 subjects (93.3%)
had no contraction after given tocolytic (27 subjects (90.0%) in nifedipine group and
29 subjects (96.7%) in terbutaline sulfate group; (p= 0.61). Subjects in nifedipine
group lost their contraction after the drug was given with median time of 1.25 (0.672.00)
hours while subjects in terbutaline sulfate group lost their contraction with
median time of 0.50 (0.50-1.50) hours (p<0.001). There was no significantly different
proportion of adverse event found in both groups. Conclusions: Nifedipine and terbutaline sulfate have relatively same efficacy to vanish uterine contraction for prematurity management. ;Background: Preterm labour is considered as one of problems frequently
encountered in obstetric and ginecologic department. To date, the incidence of
prematurity is still high worldwide. Two things should be noted: uterine contraction
and corticosteroid for lung maturity of the baby. Thus, a tocolytic agent may be useful
in these circumstances. To date, terbutaline sulfate is widely used as it is known as
beta agonist. Beside, nifedine, a calcium channel blocker, is also widely accepted. The
use of beta agonist might contribute several adverse events related to the mother,
including tachycardia, dispnea, and anxiety. Some physicians have begun to restrict
its use. Objective: This study aimed to compare the efficacy of slow release
nifedipine and terbutaline sulfate injection as a tocolytic agent for preterm labour.
Methods: This is a randomized clinical trial unblinding. Subjects were pregnant
women with prematurity (below 34 weeks of gestational age) at Cipto
Mangunkusumo hospital. Results: From a total of 60 subjects, 56 subjects (93.3%)
had no contraction after given tocolytic (27 subjects (90.0%) in nifedipine group and
29 subjects (96.7%) in terbutaline sulfate group; (p= 0.61). Subjects in nifedipine
group lost their contraction after the drug was given with median time of 1.25 (0.672.00)
hours while subjects in terbutaline sulfate group lost their contraction with
median time of 0.50 (0.50-1.50) hours (p<0.001). There was no significantly different
proportion of adverse event found in both groups. Conclusions: Nifedipine and terbutaline sulfate have relatively same efficacy to vanish uterine contraction for prematurity management. ;Background: Preterm labour is considered as one of problems frequently
encountered in obstetric and ginecologic department. To date, the incidence of
prematurity is still high worldwide. Two things should be noted: uterine contraction
and corticosteroid for lung maturity of the baby. Thus, a tocolytic agent may be useful
in these circumstances. To date, terbutaline sulfate is widely used as it is known as
beta agonist. Beside, nifedine, a calcium channel blocker, is also widely accepted. The
use of beta agonist might contribute several adverse events related to the mother,
including tachycardia, dispnea, and anxiety. Some physicians have begun to restrict
its use. Objective: This study aimed to compare the efficacy of slow release
nifedipine and terbutaline sulfate injection as a tocolytic agent for preterm labour.
Methods: This is a randomized clinical trial unblinding. Subjects were pregnant
women with prematurity (below 34 weeks of gestational age) at Cipto
Mangunkusumo hospital. Results: From a total of 60 subjects, 56 subjects (93.3%)
had no contraction after given tocolytic (27 subjects (90.0%) in nifedipine group and
29 subjects (96.7%) in terbutaline sulfate group; (p= 0.61). Subjects in nifedipine
group lost their contraction after the drug was given with median time of 1.25 (0.672.00)
hours while subjects in terbutaline sulfate group lost their contraction with
median time of 0.50 (0.50-1.50) hours (p<0.001). There was no significantly different
proportion of adverse event found in both groups. Conclusions: Nifedipine and terbutaline sulfate have relatively same efficacy to vanish uterine contraction for prematurity management. , Background: Preterm labour is considered as one of problems frequently
encountered in obstetric and ginecologic department. To date, the incidence of
prematurity is still high worldwide. Two things should be noted: uterine contraction
and corticosteroid for lung maturity of the baby. Thus, a tocolytic agent may be useful
in these circumstances. To date, terbutaline sulfate is widely used as it is known as
beta agonist. Beside, nifedine, a calcium channel blocker, is also widely accepted. The
use of beta agonist might contribute several adverse events related to the mother,
including tachycardia, dispnea, and anxiety. Some physicians have begun to restrict
its use. Objective: This study aimed to compare the efficacy of slow release
nifedipine and terbutaline sulfate injection as a tocolytic agent for preterm labour.
Methods: This is a randomized clinical trial unblinding. Subjects were pregnant
women with prematurity (below 34 weeks of gestational age) at Cipto
Mangunkusumo hospital. Results: From a total of 60 subjects, 56 subjects (93.3%)
had no contraction after given tocolytic (27 subjects (90.0%) in nifedipine group and
29 subjects (96.7%) in terbutaline sulfate group; (p= 0.61). Subjects in nifedipine
group lost their contraction after the drug was given with median time of 1.25 (0.672.00)
hours while subjects in terbutaline sulfate group lost their contraction with
median time of 0.50 (0.50-1.50) hours (p<0.001). There was no significantly different
proportion of adverse event found in both groups. Conclusions: Nifedipine and terbutaline sulfate have relatively same efficacy to vanish uterine contraction for prematurity management. ]"
2015
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