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"ABSTRAKLatar belakang. Adanya peningkatan angka kematian anak di negara berkembang, masih tingginya insiden penyakit infeksi bakteri serius (IBS) pada anak, beragamnya variabel klinis yang menjadi faktor risiko terjadinya IBS, model skoring yang ada belum teruji dalam mendeteksi IBS di sarana pelayanan terbatas.Tujuan. Untuk mengetahui validitas Skor RCPCH dalam mendeteksi adanya infeksi bakteri serius pada anak dengan demam serta mencari faktor prediktor terjadinya infeksi tersebut.Metode. Uji diagnostik untuk mengetahui validitas Skor RCPCH dalam mendeteksi adanya infeksi serius pada anak dengan demam dan kohort prospektif untuk mencari faktor prediktor. Baku emas adalah diagnosis akhir sesuai ICD-10. Seluruh pemeriksaan dilakukan secara buta (tersamar).Hasil. Didapatkan 260 subyek penelitian. Tujuh pasien rawat jalan tidak dapat dihubungi sehingga analisis dilakukan pada 253 subyek (97,3%). Laki-laki lebih banyak daripada perempuan dengan rasio 1,14: 1. Kelompok umur lebih banyak didapatkan pada kelompok > 36 bulan (51,4%). Diagnosis IBS didapatkan pada 28,9% subyek dengan diagnosis terbanyak pneumonia (19%). Skor RCPCH mempunyai sensitifitas 58,9%, spesifisitas 86,7%, nilai duga positif 64,2%, nilai duga negatif 83,8%, rasio kemungkinan positif 4,42, rasio kemungkinan negatif 0,47, post test probability 64,23%, area under ROC curve 72,8%. Batuk, sesak napas, mencret, kejang, umur 1-36 bulan, suhu tubuh ≥ 37,50 C, hipoksia, dan takipnea merupakan faktor prediktor terjadinya IBS.Simpulan. Skor RCPCH dapat digunakan untuk memprediksi infeksi bakteri serius pada anak umur 1 bulan–12 tahun. Batuk, sesak napas, mencret, kejang, umur 1-36 bulan, suhu tubuh ≥ 37,50 C, hipoksia, dan takipnea merupakan faktor prediktor terjadinya IBS.

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ABSTRACTBackground. The increase of child mortality in developing country, the high incidence of serious bacterial infection in children, the variety of risk factors of serious infections, current scoring model has not been tested in limited health care centre.Objective. To know the validity of of Royal College of Paediatrics and Child Health (RCPCH) Score to predict serious bacterial infection in children with fever and to find predictor factors of the serious infection.Method. Diagnostic study was used to find validity of RCPCH Score and cohort prospective study to find predictor factors of the serious infection. Gold standard was the latest diagnosis noted on medical record based on ICD-10. All tests were done blind.Results. There were 260 subjects. Seven patients of out-patient department could not be reached so analysis was done on 253 subjects (97.3%). There were more male than female with the ratio of 1.14:1. Age group of >36 months dominated the subject population (51.4%). Serious bacterial infection was found on 28.9% subject with the most diagnosis was pneumonia (19%). Sensitivity of SBI score was 58.9%, specificity was 86.7%, positive predictive value was 64.2%, negative predictive value was 83.8%, positive likelihood ratio was 4.42, negative likelihood ratio was 0.47, post test probability was 64,23%, and area under ROC curve was 72,8%. Cough, dyspnea, diarrhea, seizure, age of 1-36 month, body temperature ≥ 37.50 C, hypoxia, tachypnea were the risk factors for SBI.Conclusion. RCPCH Score can used to predict serious bacterial infection in children aged 1 month- 12 years. Cough, dyspnea, diarrhea, seizure, age of 1-36 months, body temperature ≥ 37.50 C, hypoxia, and tachypnea were the risk factors for SBI"

"ABSTRAKLatar belakang:Sepsis adalah infeksi bakteri dalam darah yang sangat serius (SBI) karena akan mengancam jiwa. Masih tingginya angka kematian balita karena infeksi berat dan keterbatasan fasilitas di rumah sakit daerah untuk mendiagnosis terjadinya SBI,maka penilaian secara klinis dengan menggunakan standar yang valid dalam menegakkan diagnosis SBI sangat diperlukan.Salah satu metode yang dapat digunakan untuk menilai apakah anak diprediksi menderita SBI adalah dengan skala Acute illness observation scale (AIOS). Peneliti terdahulu menemukan skalaAIOS >8 mempunyai titik potong paling baik, tapi validasi keakuratannya perlu diteliti lebih lanjut. Tujuan:Melakukan validasi menggunakan skala AIOS>8 untuk mendeteksi terjadinya infeksi bakteri serius pada usia 3-36 bulan yang datang dengan demam, dan membandingkannya dengan diagnosis akhir dari dokter spesialis anak.Metode :Uji diagnostik potong lintang dan validasi skor menggunakan tabel dua kali dua, untuk mendapatkan nilai sensitifitas, spesifisitas, nilai duga positif, nilai duga negatif dan rasio kemungkinan positif dan negatif. Hasil penelitian :Dari 143 sampel, subjek penderita SBI sebesar 44(30,77%), proporsi anak laki-laki sama dengan perempuan. dan usia terbanyak adalah 3-12 bulan yaitu 27(61,4%) subjek. Subjek penderita SBI dengan skoring AIOS > 8 sebanyak 41( (93,2%%). Penyakit SBI terbanyak adalah pnemonia 21(47,7%) subjek, diikuti ISK (13,6%), diare bakterial, sepsis dan ensefalitis masing masing (9,1%), selulitis (6,8%) dan meningitis (4,6%) dan penyakit bukan SBI terbanyak adalah ISPA 36(36,4%) subjek. Sensitifitas skor AIOS 95,5% (IK 95%; 84,5-99,4%), spesifisitas 29,3% (IK 95%; 20,6-39,3%), nilai duga positif 37,5% (IK 95%; 34,3-40,9%), nilai duga negatif 93,6% (IK 95%; 78,4-98,3%), rasio kemungkinan positif 1,4 (IK95%; 1,2-1,6), rasio kemungkinan negatif 0,2 (IK95%; 0,04-0,6). AUC(area under receiver operating characteristic curve 0,655 dengan p 0,002 dan IK 95% 0,6-0,8) dapat mendiskriminasi pasien-pasien yang dicurigai SBI dengan baik. Kesimpulan : Penggunaan skala AIOS>8 sangat sensitif untuk mendeteksi terjadinya infeksi bakteri serius pada usia 3-36 bulan.

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ABSTRACTBack ground. Sepsis is a very serious bacterial infection in the blood (SBI) because it will be life-threatening. The high rates of under-five mortality due to severe infections and limited facilities in local hospitals, a clinical assessment must be use a valid standard to diagnose SBI. One method that can be used to assess whether a child is predicted to have SBI is the scale of the Acute illness observation scale (AIOS). The previous researcher found that the scale of AIOS > 8 has the best cutoff point, but the validation of accuracy needs to be further investigated.. Aim: Validate using AIOS scale> 8 to detect the occurrence of serious bacterial infections at the age of 3-36 months who come with fever, and compare it with the final diagnosis of pediatrician.Method. The cross-sectional diagnostic test and the scoring validation use the two-by-two tables, to obtain sensitivity, specificity, positive predictor, negative predictor and positive and negative probability ratios. Result. Of the 143 samples, the subject of SBI was 44 (30.77%), the proportion of boys was the same as for women. And the most ages were 3-12 months ie 27 (61.4%) subjects. Subjects of SBI patients with AIOS scores > 8 were 41 ((93.2 %%) .The highest SBI disease was pneumonia 21 (47.7%) subjects, followed by UTI (13.6%), bacterial diarrhea, sepsis and encephalitis respectively (9,1%), cellulitis (6.8%) and meningitis (4.6%) and non-SBI disease were mostly ARI 36 (36.4%) subjects, AIOS score sensitivity 95.5% (95% IK; 84,5-99,4%), specificity 29,3% (95% IK, 20,6-39,3%), positive predictive value 37,5% (95% IK, 34,3-40,9% ), A negative predictive value of 93.6% (95% IK, 78.4-98.3%), a positive likelihood ratio of 1.4 (IK95%, 1.2-1.6), a negative likelihood ratio of 0.2 ( IK95%; 0.04-0.6). AUC (area under receiver operating characteristic curve 0.655 with p 0.002 and 95% IK 0.6-0.8) can discriminate well-suspected SBI patients. Conclusion. The use of AIOS scale> 8 is very sensitive to detect serious bacterial infections at 3-36 months of age in area."

"Pneumonia pada balita masih merupakan masalah kesehatan utama baik di dunia maupun di Indonesia. Di Indonesia, Pneumonia merupakan penyebab kematian nomor dua pada bayi dan anak balita. Kecamatan Cakung merupakan salah satu daerah yang memiliki kasus pneumonia pada balita yang cukup banyak. Penelitian ini bertujuan untuk mengetahui faktor risiko yang berhubungan dengan kejadian pneumonia pada balita di wilayah Puskesmas Kecamatan Cakung. Penelitian ini menggunakan desain studi case control. Populasi penelitian adalah balita usia 12-59 bulan yang berada di Wilayah Puskesmas Kecamatan Cakung. Hasil penelitian menunjukkan ada hubungan antara paparan asap rokok dalam rumah (OR=4,67; 1,19-18,33); tingkat konsumsi rokok (OR=2,77; 1,12-6,86), pencahayaan alami dalam rumah (OR=5,16; 1,94-13,70); pengetahuan ibu (OR=3,85; 1,12-13,25), status gizi (OR=9,14; 1,90-43,89), riwayat imunisasi (OR=3,85; 1,12-13,25) dan riwayat ASI ekslusif (OR=3,11; 1,24-7,78) terhadap kejadian pneumonia pada balita di wilayah Puskesmas Kecamatan Cakung. Faktor yang diprediksi paling dominan mempengaruhi kejadian pneumonia adalah status gizi (OR=5,607; 1,082-29,058).

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Pneumonia in children under five is still major public health problem in the world or in Indonesia. In Indonesia, Pneumonia is the number two cause of death in infants and children under five. Cakung sub-district is one of the areas that have quite a lot cases of pneumonia in children under five. This study aimed to determine the risk factors associated with the incidence of pneumonia in children under five in the region of Cakung sub-district health center. This study uses a case control study design. The population in this study are all of children aged 12 month until 59 months who lived in the region of Cakung sub-district health center.

The results of this study indicate that there was a significant correlation between exposure to secondhand smoke in the home (OR = 4.67; 1.19 to 18.33); the number of ciggarates smoked per day (OR=2,77; 1,12-6,86), lighting in the home (OR = 5.16; 1.94 to 13.70), knowledge of mothers (OR = 3.85; 1.12 to 13.25), nutritional status (OR = 9.14; 1.90 to 43.89), immunization history (OR = 3.85; 1.12 to 13 , 25) and a history of exclusive breastfeeding (OR = 3.11; 1.24 to 7.78) with the incidence of pneumonia among children under five in the region of Cakung sub-district health center. The variable that predicted the most dominant cause of pneumonia is the nutritional status (OR = 5.607; 1.082 to 29.058)."

"Masalah kesehatan kulit merupakan hal yang menarik untuk diteliti lebih lanjut. Sudah terdapat banyak penelitian yang memusatkan kepada perkembangan atau penemuan solusi kesehatan kulit. Namun, penelitian mengenai produk kesehatan kulit yang bahan bakunya bersumber dari bakteri masih perlu untuk diteliti lebih lanjut, contohnya pemanfaatan postbiotik. Produk postbiotik yang saat ini banyak diteliti adalah lisat sel Bakteri Asam Laktat (BAL). Salah satu BAL yang memiliki berbagai potensi bagi kesehatan kulit adalah Streptococcus macedonicus MBF10-2, dimana telah terbukti menghasilkan senyawa seperti asam laktat yang bersifat sebagai pelembab, antimikroba dan meremajakan kulit, eksopolisakarida, dan peptida antimikroba/bakteriosin (lantibiotik macedocin dan macedovicin). Lisat sel Streptococcus macedonicus MBF10-2 diperoleh dengan pelisisan ultrasonikasi-enzimatis, dimana sebelumnya bakteri difermentasi dalam medium de Man, Rogosa dan Sharpe (MRS) Soy Peptone. Lisat yang diperoleh menghasilkan rendemen sebesar 3,98%, 5,51%, dan 5,02%, dengan rata-rata 5,625%. Cell Free Supernatant (CSF) bakteri juga diperoleh sebagai kontrol positif pada pengujian daya hambat. Pada pengujian daya hambat dengan metode mikrodilusi menghasilkan daya hambat lisat yang lebih lemah dibandingkan Cell Free Supernatant (CSF) bakteri, yang menunjukkan bahwa lisat S. macedonicus MBF10-2 masih membutuhkan penelitian lebih lanjut untuk melihat potensi lain selain aktivitas antimikrobanya.

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Skin health problems are interesting things for further research. There has been a lot of research that focuses on the development or discovery of skin health solutions. However, research on skin health products whose raw materials are sourced from bacteria still needs further investigation, for example postbiotic use. The postbiotic product that is currently being studied is lysate cell of Lactic Acid Bacteria (LAB). One BAL that has various potentials for skin health is Streptococcus macedonicus MBF10-2, which has been shown to produce compounds such as lactic acid which are moisturizing, antimicrobial and rejuvenating skin, exopolysaccharide, and antimicrobial/bacteriocin peptides (lantibiotic macedocin and macedovicin). Streptococcus macedonicus MBF10-2 cell lysates can be obtained by ultrasonication-enzymatic disruptiom, where previously bacteria were fermented in the medium de Man, Rogosa and Sharpe (MRS) Soy Peptone. The lysate yield that was calculated are 3.98%, 5.51%, and 5.02%, with an average of 5.625%. Bacterial Cell Free Supernatant (CSF) was also obtained as a positive control in inhibitory testing. In testing the inhibition by microdilution method concludes that the inhibition level of lysate is weaker than bacterial Cell Free Supernatant (CSF), which indicates that lysate of S. macedonicus MBF10-2 still needs further research to see other potentials besides its antimicrobial activity."

"Angka kesintasan dan kualitas hidup anak dengan penyakit hepatobilier kronik meningkat seiring dengan berkembangnya transplantasi hati. Insidens infeksi bakteri 36–79% pada 6 bulan pascatransplantasi dan mortalitasnya 3,0–10,6% pada 3 bulan pascatransplantasi. Pencegahan infeksi bakteri yang adekuat akan menurunkan angka morbiditas dan mortalitas serta meningkatkan kesintasan pasien. Penelitian ini bertujuan untuk mengetahui faktor risiko infeksi bakteri pada anak pascatransplantasi hati di Indonesia. Penelitian kohort retrospektif ini melibatkan pasien anak pascatransplantasi hati di RSUPN Dr. Cipto Mangunkusumo (RSCM) mulai Desember 2010 s/d April 2023 dengan metode total sampling. Subjek dibagi menjadi kelompok infeksi bakteri dan tanpa infeksi bakteri. Prevalens infeksi bakteri dari 63 subjek penelitian ini adalah 84,13%. Infeksi bakteri didominasi oleh hospital acquired infection (HAI) berupa infeksi daerah operasi (29,63%), ventilator-associated pneumonia (14,81%), dan catheter-related urinary tract infection (13,58%). Angka mortalitas terkait infeksi bakteri adalah 12,70%. Analisis multivariat menunjukkan lama rawat ICU ≥ 20 hari (RR 1,212, IK 95% 1,028 −1,426, p = 0,022) dan volume kehilangan darah selama operasi ≥ 70 mL/kg (RR 1,283, IK 95% 1,009 −1,631, p = 0,042) adalah faktor risiko infeksi bakteri pascatranspantasi hati. Besar post-hoc power dari masing-masing uji hipotesis yang digunakan adalah 5,07−71,50%. Hasil analisis subgrup menunjukkan lama rawat ICU ≥ 20 hari memiliki risiko 2,479 kali lebih besar untuk mengalami infeksi bakteri multi-drug resistance (IK 95% 1,185 – 5,187, p = 0,016). Sebagai kesimpulan, prevalens infeksi bakteri pada anak dalam kurun waktu 0–6 bulan pascatransplantasi hati di RSCM adalah sebesar 84,13%, dengan faktor risiko berupa lama rawat ICU ≥ 20 hari dan volume kehilangan darah selama operasi ≥ 70 mL/kg. Penelitian lanjutan dengan desain lebih baik dan subjek lebih banyak diperlukan.

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Survival rate and quality of life of children with chronic hepatobiliary disease has improved since the development of liver transplantation. Incidence of bacterial infection is 36–79% at 6 months post-transplantation and mortality of 3.0–10.6% at 3 months post-transplantation. Adequate prevention of bacterial infection will reduce morbidity and mortality and increase survival. This study aimed to determine the risk factors for bacterial infection in children who underwent liver transplantation in Indonesia. This retrospective cohort study includes pediatric recipients who underwent liver transplantation in Cipto Mangunkusumo Hospital (CMH) during December 2010 – April 2023 with total sampling method. Subjects were classified into groups with and without bacterial infection. Prevalence of bacterial infection of the 63 subjects was 84.13%. A majority of the bacterial infection cases were hospital-acquired infections (HAIs), comprising of surgical site infections (29.63%), ventilator-associated pneumonia (14.81%), and catheter-related urinary tract infections (13.58%). Multivariate analysis showed ICU length of stay ≥20 days (RR 1.212; CI 95% 1.028 −1.426; p = 0.022) and volume of blood loss volume during surgery ≥70 mL/kg (RR 1.283; CI 95% 1.009 −1.631; p = 0.042) were risk factors risk factors for bacterial infection following liver transplantation. Post-hoc power of each hypothesis test was 5.07−71.50%. Subgroup analysis presented ICU length of stay ≥20 days increased risk of multi-drug resistance bacterial infection by 2.479 times (CI 95% 1.185 – 5.187; p = 0.016). Conclusions, Bacterial infection prevalence at six-months post-liver transplantation of children in CMH was 84.13% with ICU length of stay ≥20 days and volume of blood loss volume during surgery ≥70 mL/kg  as risk factors. Further studies with better design and more participants are needed."

"Latar Belakang: Anak jalanan yang jumlahnya terus meningkat, merupakan kelompok berisiko tinggi terhadap berbagai masalah sosial dan kesehatan, namun belum ada informasi tentang pengetahuan, sikap, dan perilaku mereka yang berisiko penularan HIV/AIDS.Tujuan: Mengetahui tingkat pengetahuan dan sikap terhadap HIV/AIDS, serta perilaku berisiko tinggi penularan HIV/AIDS dan faktor yang memengaruhinya pada anak jalanan usia remaja di Jakarta.Metode: Studi kuantitatif (kuesioner yang divalidasi) dan kualitatif (wawancara, focus group discussion, dan observasi) terhadap 100 subjek usia 10-18 tahun yang dipilih secara konsekutif. Analisis statistik menggunakan analisis bivariat (uji kai kuadrat atau uji Fischer) dan multivariat (uji regresi logistik).Hasil: Sebagian besar (85%) subjek memiliki tingkat pengetahuan dan sikap yang masih kurang terhadap HIV/AIDS, 35% subjek belum pernah mendengar istilah HIV/AIDS. Tingkat pendidikan dan status ekonomi keluarga merupakan faktor yang memengaruhi pengetahuan dan sikap terhadap HIV/AIDS. Perilaku risiko tinggi penularan HIV/AIDS melibatkan 27% subjek, risiko sedang 18% subjek, risiko rendah 55% subjek. Sebanyak 17% subjek pernah berhubungan seksual (82,4% tidak pernah menggunakan kondom), 58% perokok; 45% peminum alkohol, 26% pengguna obat-obatan terlarang. Prostitusi dan homoseksualitas juga didapatkan pada anak jalanan. Usia, jenis kelamin, tingkat pendidikan, lama bekerja, jumlah jam kerja, tempat tinggal, frekuensi bertemu orangtua kandung, dan sumber informasi utama merupakan faktor yang memengaruhi tingkat perilaku risiko tinggi.Simpulan: Anak jalanan memiliki tingkat pengetahuan dan sikap yang kurang terhadap HIV/AIDS serta banyak terlibat perilaku berisiko tinggi, sehingga membutuhkan penanganan yang komprehensif dan multidisiplin.

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Background: Street children are increasing and highly vulnerable to many social and health problems, but very little is known about their knowledge, attitudes, and behavior related to HIV/AIDS transmission.

Objectives: To identify level of knowledge, attitudes, and high-risk behavior related to HIV/AIDS transmission among adolescent street children in Jakarta and its related factors.

Methods: Quantitative (validated questionnaire) and qualitative (in-depth interview, focus group discussion, and observation) study were conducted among 100 participants aged 10-18 years old which were recruited consecutively. Statistical analysis was done using bivariate (Chi-square or Fischer tests) and multivariate (logistic regression) analysis.

Results: Most participants (85%) had low knowledge about HIV/AIDS and 35% subjects never heard about HIV/AIDS. Low education level and low socio-economic status increased likelihood of having low knowledge about HIV/AIDS. High-risk behaviors were engaged by 27% participants, moderate risk 18%, low risk 55% participants. Seventeen percent subjects were sexually experienced (82,4% never use condom), 58% smokers, 45% alcohol drinkers, and 26% drug abusers. Prostitution and homosexuality were also prevalent among street children. Factors that increased the likelihood of displaying risky behavior were being male, older age, low education level, being street children more than 5 years, working on the street more than 35 hours a week, living on the street, less contact with parents, and having friend as major source of information.

Conclusions: Street children had low knowledge and attitude toward HIV/AIDS and high engagement on high-risk behavior, thus require comprehensive and multidisciplinary approaches."

"Skripsi ini membahas mengenai pengaruh promosi kesehatan terhadap pengetahuan, sikap dan praktek cuci tangan pakai sabun pada siswa kelas 5 di SDN Pengasinan IV Kota Bekasi Tahun 2012. Penelitian ini menggunakan penelitian kuantitatif pra eksperimental dengan rancangan one group pre test and post test. Populasi penelitian ini adalah siswa kelas 5 SDN Pengasinan IV Kota Bekasi sebanyak 93 orang dan seluruh siswa menjadi responden penelitian. Pemilihan sekolah dilakukan secara purposif.Dari hasil pengolahan data diketahui bahwa terjadi peningkatan pengetahuan, sikap dan praktek cuci tangan pakai sabun pada siswa kelas 5 SDN Pengasinan IV Kota Bekasi sebesar 22,8% untuk variabel pengetahuan, 4,2% untuk variabel sikap dan 17,4% untuk variabel praktek. Hal ini menunjukkan bahwa intervensi yang dilakukan terbukti dapat meningkatkan pengetahuan, sikap dan praktek siswa kelas 5 SDN Pengasinan IV Kota Bekasi mengenai cuci tangan pakai sabun. Diharapkan pihak sekolah dapat terus melaksanakan program-program kesehatan di sekolah serta menjalin kerjasama dengan pihak Puskesmas dan Dinas Kesehatan dalam meningkatkan dan mengembangkan program promosi kesehatan di sekolah.

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This research discusses the effects of health promotion towards the knowledge, attitudes, and practices of washing hands using soap in 5th grade students of SDN Pengasinan IV, Bekasi Country in 2012. This study uses pre-experimental quantitative research with one group pre test and post test design. The population of this research were 93 5th grade pupils of SDN Pengasinan IV and students are the respondents of the research. The selection of school as places of research has done purposively.The results of data processing are the increasing knowledge, attitudes, and practices of washing hands using soap of 5th grade students of SDN Pengasinan IV, Bekasi Country. The knowledge increases 22,8%, the attitude increases 4,2%, and the practice increases 17,4%. Those increasing percentage have proven that interventions, which have been conducted, are succeed to increase knowledge, attitudes,and practices of washing hands using soap in 5th grade students of SDN Pengasinan IV, Bekasi Country. The writer is expecting that SDN Pengasinan IV will continue to carry out health programs in schools as well as work together with Health Centre and Health Department in increasing and developing health promotion programs in schools."

"Latar belakang: Banyak faktor yang memengaruhi stimulasi dan salah satunya adalah stimulasi. Fungsi kognitif berhubungan dengan stimulasi yang diberikan oleh orangtua atau pengasuh.Tujuan: Menilai hubungan stimulasi dengan fungsi kognitif anak perawakan pendek dan normal usia prasekolahMetode: Studi cross sectional yang dilakukan di empat kelurahan di Jakarta dengan metode pengambilan sampel secara consecutive sampling. Kriteria inklusi adalah anak usia prasekolah dari penelitian pada perawakan pendek sebelumnya dengan orangtua atau pengasuh. Penilaian stimulasi menggunakan kuesioner versi Bahasa Indonesia dan fungsi kognitif dengan the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) versi Bahasa Indonesia yang dinilai oleh Psikolog. Analisis data dengan uji korelasi Pearson dan Kai kuadrat, hasil signifikan bila nilai p < 0,05Hasil: Subjek 62 anak yang terdiri dari 22 (35,5%) perawakan pendek dan 40 (64,5%) perawakan normal. Pada perawakan pendek didapatkan yang terbanyak stimulasi perkembangan kategori sedang (54,5%), proporsi IQ verbal dan total rata-rata (59,1% dan 50,0%), proporsi IQ performa di bawah rata-rata (45,5%). Hubungan stimulasi dengan fungsi kognitif IQ total pada anak perawakan normal (r=0,316; p=0,047). Perbedaan proporsi IQ verbal, IQ performa dan IQ total pada perawakan pendek dan normal (p=0,409; p=0,119; p=0,877).Simpulan: Terdapat hubungan bermakna antara stimulasi dengan fungsi kognitif. Tidak terdapat perbedaan proporsi penilaian kognitif dari rata-rata ke atas pada IQ verbal, IQ performa dan IQ total pada perawakan pendek dan normal. Hasil ini harus diinformasikan kepada orangtua atau pengasuh bahwa stimulasi memengaruhi fungsi kognitif dan harus dilakukan rutin setiap hari.

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Background: Several factors influence cognitive function and stimulation is one of them. Cognitive function is related to stimulation given by parents or caregivers.

Aim: To assess correlation between stimulation with cognitive function of preschool children with normal and short stature.

Methods: A cross-sectional study with a consecutive sampling was done in four sub-districts in Jakarta. Inclusion criteria were preschool-age children from the previous research on short stature and their parents or caregivers. Stimulation assessment using an Indonesian questionnaire version. Verbal IQ (VIQ), performance IQ (PIQ), and full-scale IQ (FSIQ) were assessed with the Wechsler Preschool and Primary Scale of Intelligence (WPPSI) Indonesian version by Psychologist. Data were analyzed using Pearson correlation and Chi-square test with a statistically significant if p-value <0.05.

Results: Subject of 62 children consist of 64.5% normal and 35.5% short stature. Most of short stature children obtained medium category stimulation (54.5%), an average VIQ and FSIQ proportion (59.1% and 50.0%, respectively), below the average PIQ proportion (45.5%). Correlation between stimulation with FSIQ (r= 0.316; p-value= 0.047) in normal stature. Verbal IQ, PIQ and FSIQ proportion difference from an average and above between normal and short stature children were p-value= 0.409; p-value= 0.119; p-value= 0.877, respectively.

Conclusion: There was a significant correlation between stimulation and cognitive function. Cognitive function from an average and above between normal and short stature is no proportion difference. This finding must be informed to the parents or caregivers that stimulation affects the cognitive function, and it must be done every day regularly."