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Budiyanto Abdul Rohim
Uji diagnostik pemeriksaan ultrasonografi dibandingkan pemeriksaan klinis dalam mengukur ukuran lesi primer kanker serviks = Diagnostic performance of ultrasound compare to clinical examination in measuring the size of primary tumor of cervical cancer
"[ABSTRAK
Tujuan. Penelitian ini membahas perbandingan performa diagnostik antara pemeriksaan ultrasonografi dengan pemeriksaan klinis dalam mengukur ukuran lesi primer kanker serviks.
Metode. Dilakukan uji diagnostik potong-lintang secara retrospektif terhadap pasien kanker serviks stadium IB di RSUPN Dr. Ciptomangunkusumo dari tahun 2009 hingga tahun 2014. Nilai diagnostik dari kedua pemeriksaan dihitung dengan luaran: sensitivitas, spesifisitas, nilai prediksi positif, nilai prediksi negatif, dan akurasi. Uji kesesuaian dari kedua pemeriksaan juga dihitung dengan ukuran makroskopik sebagai standar baku emas.
Hasil. Dari periode tahun 2009 hingga tahun 2014, didapatkan 92 subjek yang memenuhi kriteria inklusi dengan komposisi yaitu 65 kasus (70%) kanker serviks stadium IB1 dan 27 kasus (30%) kanker serviks stadium IB2. Ultrasonografi didapatkan memiliki nilai diagnostik yaitu sensitivitas 92%, spesifisitas 96%, nilai prediksi positif 92%, nilai prediksi negatif 96%, dan akurasi 95%. Sementara itu, pemeriksaan klinis didapatkan memiliki nilai diagnostik yaitu sensitivitas 51%, spesifisitas 92%, nilai prediksi positif 73%, nilai prediksi negatif 82%, dan akurasi 80%. Dari perhitungan kesesuaian antara ukuran pemeriksaan ultrasonografi dan ukuran makroskopik, didapatkan perbedaan rata-rata 0,56 cm. Sementara itu, dari perhitungan kesesuaian antara ukuran pemeriksaan klinis dan ukuran makroskopik, didapatkan perbedaan rata-rata 0,97 cm.
Kesimpulan. Penelitian ini menyimpulkan bahwa pemeriksaan ultrasonografi memiliki performa diagnostik yang lebih baik dibandingkan pemeriksaan klinis dalam mengukur ukuran lesi primer kanker serviks.
ABSTRACT
Objective. The purpose of this study is to compare the diagnostic value of ultrasound and clinical examination in measuring the size of primary tumor of cervical cancer.
Methods. It is a retrospective cross sectional study for patients with cervical cancer stage IB in Cipto Mangunkusumo hospital from 2009 to 2014. Diagnostic value of both examinations were calculated with outcome: sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. Resemblance test of both examinations were also calculated with macroscopic size as the gold standart.
Result. From period 2009 until 2014, there were 92 subject which fulfilled the inclusion criteria, consisted of 65 cases (70%) cervical cancer stage IB1 and 27 cases (30%) cervical cancer stage IB2. Ultrasonografi was found to have diagnostic values as follow: sensitivity 92%, specificity 96%, positive predictive value 92%, negative predictive value 96%, and accuracy 95%. Meanwhile, clinical examination was found to have diagnostic values as follow: sensitivity 51%, specificity 92%, positive predictive value 73%, negative predictive value 82%, and accuracy 80%. From the calculation of resemblance between ultrasound and macroscopic size, there was an average difference approximately 0.56 cm. Meanwhile, from the calculation of resemblance between clinical examination and macroscopic size, there was an average difference approximately 0.97 cm.
Conclusion. It can be concluded that the ultrasound has better diagnostic value compare to clinical examaination in examining the size of primary tumor of cervical cancer., Objective. The purpose of this study is to compare the diagnostic value of ultrasound and clinical examination in measuring the size of primary tumor of cervical cancer.
Methods. It is a retrospective cross sectional study for patients with cervical cancer
stage IB in Cipto Mangunkusumo hospital from 2009 to 2014. Diagnostic value of both
examinations were calculated with outcome: sensitivity, specificity, positive predictive value,
negative predictive value, and accuracy. Resemblance test of both examinations were also
calculated with macroscopic size as the gold standart.
Result. From period 2009 until 2014, there were 92 subject which fulfilled the inclusion
criteria, consisted of 65 cases (70%) cervical cancer stage IB1 and 27 cases (30%) cervical
cancer stage IB2. Ultrasonografi was found to have diagnostic values as follow: sensitivity
92%, specificity 96%, positive predictive value 92%, negative predictive value 96%, and
accuracy 95%. Meanwhile, clinical examination was found to have diagnostic values as follow:
sensitivity 51%, specificity 92%, positive predictive value 73%, negative predictive value 82%,
and accuracy 80%. From the calculation of resemblance between ultrasound and macroscopic
size, there was an average difference approximately 0.56 cm. Meanwhile, from the calculation
of resemblance between clinical examination and macroscopic size, there was an average
difference approximately 0.97 cm.
Conclusion. It can be concluded that the ultrasound has better diagnostic value compare to clinical examaination in examining the size of primary tumor of cervical cancer.]"
Fakultas Kedokteran Universitas Indonesia, 2014
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UI - Tugas Akhir  Universitas Indonesia Library
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Sulaeman Daud
Kelainan lesi prakanker serviks melalui papsmear pada pemeriksaan IVA dengan tampilan sambungan skuamo-kolumnar tidak tampak = Cervical pre cancer lesion with diagnosed by papsmear examination and IVA in women with unvisible squamo-columnar junction
"ABSTRAK
Tujuan : Untuk mengetahui kelainan yang tersembunyi pada keadaan
Sambungan Skuamo-Kolumnar (SSK) tidak tampak melalui pemeriksaan
Papsmear.
Metode : Penelitian ini merupakan deskriptif potong lintang (Cross Sectional).
Penelitian dilakukan pada periode Agustus 2014 sampai Maret 2015 di beberapa
Puskesmas di Jakarta. Sebanyak 1682 subjek yang dilakukan pemeriksaan IVA
(Inspeksi Visual dengan Asam asetat). Setelah data dikumpukan, akan dilakukan
verifikasi data, editing dan coding. Analisis data statistik berupa deskriptif
variabel kategorik yaitu persentase letak Sambungan Skuamo-Kolumnar (SSK)
berdasarkan distribusi umur, persentase hasil pemeriksaan IVA berdasarkan SSK,
dan persentase hasil pemeriksaan Papsmear pada SSK yang tidak tampak dari
hasil pemeriksaan IVA negatif disajikan dalam bentuk n%.
Hasil : Perempuan dengan Sambungan Skuamo-Kolumnar (SSK) yang tampak
1484 (88,2%), yang tidak tampak 198 (11,8%). Sambungan Skuamo-Kolumnar
(SSK) yang tidak tampak pada perempuan yang sudah menopause 122 (61,6%),
sedangkan pada perempuan yang belum menopause 76 (38,4%). Hampir
setengahnya proporsi SSK yang tampak didapatkan pada kelompok perempuan
yang sudah menopause 45,78% (103/225). Hasil pemeriksaan IVA positif
didapatkan 4(7,1%) pada kelompok perempuan menopause dan 52(92,9%) pada
kelompok perempuan yang belum menopause. Pada pemeriksaan Papsmear
dengan SSK yang tidak tampak, persentase kelainan lesi prakanker yaitu sebesar
0(0,0%) ASCUS, 0(0,0%) LSIL, 0(0,0%) HSIL, dan 197(100%) normal.
Kesimpulan : Hampir setengahnya Sambungan Skuamo-Kolumnar (SSK) yang
tampak ditemukan pada kelompok perempuan menopause. Sebagian besar IVA
positif ditemukan pada kelompok perempuan yang belum menopause. Seluruh perempuan dengan SSK yang tidak tampak memiliki hasil pemeriksaan Papsmear normal. ABSTRACT Objective: To know is there any concealed precancer lesion in women with
unvisible Squamo-Columnar Junction (SCJ) by Papsmear examination.
Methods : This study was a descriptive cross-sectional design starting from
August 2014 to March 2015 at several Public Health Care in Jakarta. A total of
1682 subjects were screening by Acetoacetate Visual Inspection (AVI)
examination. After the data was collected, and continued by verification, editing
and coding. The analysis from the data by variable categoric descriptive like
percentage of SCJ in age distribution, percentage the result of AVI examination
based on SCJ and percentage the result of Papsmear examination in unvisible
SCJ from negative AVI result. All the result would be present in n%.
Results : Women with the visible SCJ were 1484(88,2%) and women with
unvisible SCJ were 198(11,8). The percentage of unvisible SCJ in the menopausal
women group were 122(61,6%), However, in the non-menopausal women group
were 76(38,4%). Almost a half of the percentage of visible SCJ found in
menopausal women group 45,78%(103/225). The positive AVI result was 4(7,1%)
in the menopausal women group and 52(92,9%) in non-menopausal women grup.
The result of papsmear examination with unvisible SCJ were 0(0,0%) ASCUS,
0(0,0%) LSIL, 0(0,0%) HSIL, and 197(100%) normal..
Conclusion : Almost a half of visible SCJ found in menopausal women group.
Most of positive AVI result was found in the non-menopausal women group. All
woman with the unvisible SCJ have a normal papsmear result.
;Objective: To know is there any concealed precancer lesion in women with
unvisible Squamo-Columnar Junction (SCJ) by Papsmear examination.
Methods : This study was a descriptive cross-sectional design starting from
August 2014 to March 2015 at several Public Health Care in Jakarta. A total of
1682 subjects were screening by Acetoacetate Visual Inspection (AVI)
examination. After the data was collected, and continued by verification, editing
and coding. The analysis from the data by variable categoric descriptive like
percentage of SCJ in age distribution, percentage the result of AVI examination
based on SCJ and percentage the result of Papsmear examination in unvisible
SCJ from negative AVI result. All the result would be present in n%.
Results : Women with the visible SCJ were 1484(88,2%) and women with
unvisible SCJ were 198(11,8). The percentage of unvisible SCJ in the menopausal
women group were 122(61,6%), However, in the non-menopausal women group
were 76(38,4%). Almost a half of the percentage of visible SCJ found in
menopausal women group 45,78%(103/225). The positive AVI result was 4(7,1%)
in the menopausal women group and 52(92,9%) in non-menopausal women grup.
The result of papsmear examination with unvisible SCJ were 0(0,0%) ASCUS,
0(0,0%) LSIL, 0(0,0%) HSIL, and 197(100%) normal..
Conclusion : Almost a half of visible SCJ found in menopausal women group.
Most of positive AVI result was found in the non-menopausal women group. All
woman with the unvisible SCJ have a normal papsmear result.
"
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
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Hasra Depiesa Dianika
Nilai diagnostik servikografi modifikasi dan inspeksi visual asam asetat (IVA) sebagai penapisan lesi pra kanker = Modified cervicography and visual acetoacid inspection as an alternative screening for cervical pre-cancer lesion
"ABSTRAK
Tujuan : Mengetahui nilai Akurasi Diagnostik berupa sensitivitas, spesifisitas,
nilai duga positif dan nilai duga negatif Servikografi Modifikasi dan IVA.
Metode : Penelitian yang akan dilakukan merupakan penelitian uji diagnostik
dengan membandingkan akurasi diagnostik Servikografi Modifikasi dengan IVA.
Didapatkan 185 sampel, semua sampel akan diperiksa di poliklinik Ginekologi
berturut-turut IVA, servikografi modifikasi dan kolposkopi pada Feberuari 2015 -
April 2015.
Hasil : Dari hasil pemeriksaan IVA, servikografi modifikasi dan kolposkopi
didapatkan hasil IVA positif sebanyak 7%, servikografi modifikasi dengan hasil
positif sebanyak 7.6% dan kolposkopi abnormal sebanyak 5.4%. Sehingga
didapatkan hasil sensitifitas IVA sebesar 96% dan servikografi modifikasi
sebesar 97.7%. Spesifisitas didapatkan hasil sensitifitas IVA sebesar 90.9% dan
servikografi modifikasi sebesar 90.9%.
Kesimpulan : Nilai akurasi diagnostik servikografi modifikasi dan IVA dapat
dinyatakan sebanding dan dapat digunakan bersama dengan pemeriksaan IVA
sebagai alternatif pemeriksaan lesi pra kanker.;ABSTRACT Objective : To know the difference of diagnostic accuration between acetoacetate
visual inspection and modified cervicography as an alternative screening of
cervical cancer lesion.
Methods : This was an cross-sectional study that was performed at RSUPN Dr.
Cipto Mangunkusumo from February 2015 until April 2015.
Results : 185 patients were admitted on this study. Sensitivity and specificity of
visual acetoacid inspection were 96% and 90,9%. Sensitivity and specificity of
modified cervicography were 97,7% and 90,9% compared to colposcopy as a gold
standard.
Conclusion : Modified cervicography and VIA are reliabe tools for cervical
cancer screening. Modified cervicography could be use as an alternative tool to
improve the documentation of VIA. "
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
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Talitha Ardelia Salsabila Djajasasmita
Uji Aktivitas Antioksidan dan Sitotoksik Ekstrak Spirulina Platensis Terhadap Sel Kanker Serviks HeLa = Antioxidant and Cytotoxic Activity of Spirulina Platensis Extract Toward HeLa Cervical Cancer Cells
"Kanker serviks sebagai salah satu jenis kanker yang menempati posisi kedua paling banyak ditemukan pada wanita yang disebabkan oleh infeksi human papillomavirus (HPV). Pengobatan kanker serviks secara menyeluruh belum dapat menjangkau seluruh kalangan pasien dikarenakan biayanya yang mahal dan beberapa layanan kesehatan kurang memadai sehingga diperlukan adanya alternatif pengobatan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dan aktivitas sitotoksik ekstrak Spirulina platensis terhadap sel kanker serviks HeLa. Spirulina platensis yang berupa serbuk kering dimaserasi menggunakan pelarut etanol, etil asetat, dan n-heksana secara berurut. Setiap ekstrak dievaluasi untuk mengetahui aktivitas antioksidan dan aktivitas sitotoksiknya dengan metode uji DPPH dan MTT assay. Pada uji DPPH, didapatkan nilai IC50 pada ekstrak etil asetat dan etanol Spirulina platensis sebesar 18,863 μg/mL dan 15,169 μg/mL, yang berarti aktivitas antioksidan kedua ekstrak sangat aktif terhadap radikal bebas DPPH. Berdasarkan uji MTT assay, ketiga ekstrak Spirulina platensis (ekstrak etil asetat, ekstrak etanol, dan ekstrak n-heksana) memiliki aktivitas sitotoksik terhadap sel kanker serviks HeLa dengan nilai IC50 secara berturut-turut adalah 16,615 μg/mL, 41,510 μg/mL, dan 85,455 μg/mL, sedangkan nilai IC50 kontrol positif doksorubisin terhadap sel HeLa adalah 7,209 μg/mL. Ekstrak Spirulina platensis menunjukkan adanya aktivitas antioksidan dan aktivitas sitotoksik terhadap lini sel kanker serviks HeLa melalui uji DPPH dan MTT assay.
Cervical cancer is a type of cancer that occupies the second most common position in women is caused by infection with the human papillomavirus (HPV). Treatment of cervical cancer has not been able to reach all patients due to the high cost and some inadequate health services, so that alternative treatments are needed. This study aims to determine the antioxidant activity and cytotoxic activity of Spirulina platensis extract against HeLa cervical cancer cells. Spirulina platensis in the form of dry powder was macerated using ethanol, ethyl acetate, and n-hexane in succession. Each extract was evaluated to determine its antioxidant activity and cytotoxic activity by DPPH and MTT assay methods. In the DPPH test, the IC50 values ​​for the ethyl acetate and ethanol extract of Spirulina platensis were 18,863 g/mL and 15,169 g/mL, which means the antioxidant activity of both extracts was very active against DPPH free radicals. Based on the MTT assay, the three Spirulina platensis extracts (ethyl acetate extract, ethanol extract, and n-hexane extract) had cytotoxic activity against HeLa cervical cancer cells with IC50 values ​​of 16.615 g/mL, 41,510 g/mL, and 85,455 g/mL, while the IC50 value of doxorubicin as a positive control against HeLa cells was 7.209 g/mL. Spirulina platensis extract showed antioxidant and cytotoxic activity against the HeLa cervical cancer cell line through DPPH and MTT assay."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
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UI - Skripsi Membership  Universitas Indonesia Library
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Linggih Saputro
Penapisan inhibitor tankirase-2 untuk terapi kanker serviks = Screening of tankyrase 2 inhibitors for cervical cancer therapy
"Kanker serviks merupakan kanker kedua yang umum terjadi pada wanita yang da- pat menjadi ganas. Keganasan dapat disebabkan oleh deregulasi jalur sinyal Wnt/β- katenin. Inhibisi TNKS2 dengan ligan inhibitor dapat menjadi salah satu cara un- tuk menghentikan deregulasi ini. Ligan-ligan inhibitor yang berhasil terbentuk dari fragmen-fragmen akan ditapiskan secara in silico untuk mendapatkan ligan kandi- dat obat terbaik yang lebih baik dari ligan inhibitor standar. Ligan dengan kode 1-69 merupakan ligan inhibitor yang lebih baik jika dilihat dari energi pengikatan, kelarutan, total polar surface area.
Cervical cancer is the second most common cancer in women which can be ma- lignant. Malignancy can be caused by deregulation oleh Wnt/β-catenin signaling pathway. Inhibition of TNKS2 with ligand inhibitor can be an alternative way to stop this deregulation. All of the inhibitors which assembled from fragments were screened in silico to get the best hit which is better than standard inhibitor. Ligand with codename 1-69 is a better inhibitor than the standard in the term of binding energy, solubility and total polar surface area."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2014
S55827
UI - Skripsi Membership  Universitas Indonesia Library
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Annisa Hadisty Sukana
Telaah Pemanfaatan Telemedicine Dovia dalam Skrining Kanker Serviks oleh Praktisi Medis di Indonesia = Review of The Use of Dovia Telemedicine in Screening of Cervical Cancer by Medical Practitioners in Indonesia
"Latar Belakang: Kanker serviks merupakan ancaman bagi kesehatan reproduksi perempuan di Indonesia. Dengan metode skrining yang cost effective kanker serviks dapat dicegah, sehingga angka morbiditas dan mortalitas kanker serviks dapat diturunkan. Maka diperlukan metode alternatif yang lebih sederhana dan mampu laksana sebagai metode penapisan yang dapat mencakup lapisan masyarakat dengan sumber daya terbatas. Dengan prosedur skrining IVA atau VIA (Visual Inspection with Acetic Acid), diperkirakan mengurangi risiko kanker serviks seumur hidup sebesar 25%. Kekurangan IVA adalah bahwa metode ini bersifat subjektif dan interpretasi dapat bervariasi dari operator ke operator. Oleh karena itu, timbul pemikiran untuk melakukan dokumentasi IVA menggunakan kamera Smartphone yang disebut DoVIA (Documentation Visual Inspection with Acetic Acid). Bermodalkan dokumentasi IVA ini, dapat dilakukan konsultasi dan komunikasi dengan cara mengirimkan melalui aplikasi dan rangkaian kegiatan disebut TeleDoVIA (Telemedicine Documentation Visual Inspection with Acetic Acid).
Tujuan: Evaluasi pemanfaatan Portal TeleDoVIA oleh tenaga medis dalam kegiatan skrining kanker serviks dengan metode IVA.
Metode: Penelitian ini merupakan penelitian deskriptif. Dilaksanakan dalam periode Juli 2018-Januari 2019 dengan mengikut sertakan 82 orang Praktisi Medis yang mengirimkan 177 foto Dokumentasi IVA.
Hasil: Praktisi Medis yang terlibat 59 orang (72 %) adalah bidan, 23 orang (28 %) adalah Dokter Umum yang bertugas di Puskesmas (92.7 %) dan Klinik Swasta (7.3%). Praktisi Medis yang berkonsultasi pada portal TeleDoVIA telah mencakup wilayah provinsi paling barat (Aceh) hingga Provinsi di Timur Indonesia (Papua Barat). Ketajaman gambar foto serviks dikatakan tajam sebesar (89.27%), hanya sebesar (10.73%) foto yang dikatakan kurang tajam. Mayoritas praktisi medis menerima jawaban dari konsultan dalam waktu >6-24 jam sebesar (44.1%). Praktisi medis yang mengaku paham sebesar (100 %) dan mengaku puas (100 %). Alasan praktisi medis melakukan konsultasi dengan alasan Konfirmasi (47.6%), Ragu (29.3%) dan Diskusi kasus (23.2%). Ketepatan diagnosis antara praktisi medis terhadap diagnosis konsultan sebesar (88.1%).
Kesimpulan: Dengan Telemedicine Dovia dapat memudahkan praktisi medis mengirimkan dokumentasi IVA sebagai bahan diskusi dan konsultasi jarak jauh yang efektif.
Background: Cervical cancer is a threat to women's health in Indonesia. With the screening method that is cost effective cervical cancer can be prevented, so that the cervical cancer morbidity and mortality can be reduced. Then an alternative method that is simpler and more feasible as a screening method that can cover a layer of people with limited resources is needed. The screening procedure with IVA or VIA (Visual Inspection with Acetic Acid) has been estimated to reduce the risk of lifetime cervical cancer by 25%. The disadvantage of IVA is that this method is subjective and interpretation can vary from operator to operator. Therefore, the idea arises to conduct documentation VIA using a Smartphone camera. This examination is called TeleDoVIA (Telemedicine of Documentation on Visual Inspection with Acetic Acid). With this VIA documentation, consultation and communication can be done by sending through applications and these activities called TeleDoVIA (Telemedicine Documentation Visual Inspection with Acetic Acid).
Objective: Evaluation review of the use of TeleDoVIA Portal by medical personel in the Screening of cervical cancer using the IVA method.
Method: This study is a descriptive study and was conducted in the period July 2018 - January 2019 by including 82 medical practitioners who sent 177 IVA Documentation photos.
Results: Medical practitioners that involved as much 59 people (72%) were midwives, 23 people (28%) were general practitioners who served in Public Health Center (92.7%) and private clinics (7.3%). The closest home town of medical practitioners is Central Jakarta (24.4%) and the furthest from Fakfak in West Papua (1.2%). The sharpness of cervical photographic images is said to be sharp at 89.27%, only by 10.73% photos that are not sharp enough. The majority of medical practitioners receive answers from consultants within >6-24 hour is 44.1%. the accuracy of diagnosis between medical practitioners and consultant diagnosis is 88.1%. Medical practitioners who claim to understand (75.6%) and claim to be satisfied (76.8%). Medical practitioners consulted the TeleDoVIA portal for reasons of confirmation (47.6%), doubtful (29.3%) and discussion of cases (23.2%).
Conclusion: With the presence of Telemedicine Dovia, it can make it easier for medical practitioners to send IVA documentation as a more effective discussion and consultation material even from remote area."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
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UI - Tugas Akhir  Universitas Indonesia Library
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Tutik Rahayu
Studi fenomenologi pengalaman suami dengan istri yang mengalami kanker serviks = Study phenomenology living with cervical cancer : Experience of husband
"Tujuan penelitian ini untuk memperoleh gambaran secara mendalam tentang makna pengalaman suami dengan istri yang mengalami kanker serviks. Pengambilan data dilakukan dengan cara wawancara mendalam. Pada penelitian ini ditemukan 9 tema yaitu : 1). Respon awal suami terhadap diagnosa kanker servik, 2). Pemahaman suami terhadap kanker serviks 3). Memberi dukungan kepada istri. 4). Memperoleh dukungan keluarga atau kerabat. 5). Bentuk penyesuaian suami terhadap istri dengan kanker serviks. 6). Pelajaran atau hikmah yang diperoleh setelah istri sakit. 7). Koping suami. 8). Harapan suami terhadap pengobatan istri. 9). Harapan suami terhadap pelayanan keperawatan. Peran perawat sangat dibutuhkan untuk dapat memberikan konseling pada pasangan.
Based on the study's purpose discriptive phenomenology was selected as appropriate design to discovery the essence of the experience. Results nine theme: 1). Experience during diagnosis period. 2). Husband's knowledge abaout cervical cancer. 3). Give social support for wive.4). Received social support from family and significant others. 5). Husband Adjustment with cervical cancer wive's. 6). Finding meaning in disease. 7). Husband cope. 8) Hoping wive-treatment. 9). Hoping with nursing care practice.Nurses roles needed for husbands and his partners to given counseling. And given about cervical cancer to increase husbands knowledged."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2011
T-Pdf
UI - Tesis Open  Universitas Indonesia Library
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Richard Immanuel B.
Evaluasi verifikasi lapangan radiasi pada kasus kanker serviks dan kanker nasofaring menggunakan pesawat terapi Co-60 = The evaluation of radiation field verification on the cases of cervical cancer and nasopharyngeal cancer using Co-60 teletherapy
"Penelitian ini membahas mengenai tingkat keberhasilan verifikasi kasus kanker serviks dengan kanker nasofaring. Dalam penelitian ini telah dievaluasi data film verifikasi penyinaran pasien radioterapi untuk jenis kanker serviks dan nasofaring. Jumlah pasien untuk jenis kanker serviks berjumlah 45 pasien dan untuk jenis kanker nasofaring 45 pasien. Peneliti tidak melakukan verifikasi secara langsung dan tidak berhubungan dengan pasien, Data diperoleh dari status pasien yang tersedia di Rumah Sakit Cipto Mangunkusumo . Hasil penelitian ini menunjukkan bahwa tingkat keberhasilan verifikasi kasus kanker nasofaring lebih tinggi dibandingkan dengan kasus kanker serviks.
My research study is focused on evaluating the verification success rates of cervical cancer and nasopharyngeal cancer survivors. 45 patients underwent radiotherapy procedures to identify specific types of the two mentioned cancers followed by data recording, for a total of 90 patients. The experimenter conducted no direct verification and had no direct contact with the patients since the data samples were obtained from Cipto Mangunkusumo Hospital. Research findings proved that the success rates of nasopharyngeal cancer verification were higher than the cervical cancer verification."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2010
S29432
UI - Skripsi Open  Universitas Indonesia Library
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Kiki Kurniati
Pengaruh penggunaan kontrasepsi terhadap kejadian lesi prakanker leher rahim pada wanita yang melakukan pemeriksaan inspeksi visual dengan asam asetat (IVA) di 3 Puskesmas di Jakarta Timur tahun 2011 = Effect of contraceptive use against the incindes of cervical lesions in women who conducting visual inspection with acetic acid in 3 Primary Health Care in East Jakarta District in 2011
"ABSTRAK
Skripsi ini menjelaskan mengenai pengaruh penggunaan kontrasepsi
terhadap kejadian lesi prakanker leher rahim. Penelitian dilakukan dengan menggunakan disain studi kasus-kontrol dan data sekunder yang berasal dari catatan medis deteksi dini kanker leher rahim di 3 puskesmas kecamatan di wilayah Jakarta Timur. Jumlah sampel yang diteliti adalah 86 orang untuk kelompok kasus dan 258 orang untuk kelompok kontrol. Hasil penelitian ini menemukan bahwa terdapat hubungan yang bermakna secara statistik antara penggunaan kontrasepsi non-hormonal dengan kejadian lesi prakanker (nilai-p <
α, dimana α = 0,05), dimana wanita yang menggunakan kontrasepsi non-hormonal memiliki risiko 4 kali lebih tinggi untuk mengalami kejadian lesi prakanker dibandingkan dengan wanita yang tidak pernah menggunakan metode kontrasepsi apapun, sedangkan risiko wanita yang menggunakan kontrasepsi hormonal tidak berbeda dengan wanita yang tidak pernah menggunakan metode kontrasepsi untuk mengalami kejadian lesi prakanker.
ABSTRACT
This thesis describes the effect of contraceptive use against the incidence of cervical lesions. This study uses a case-control study design with secondary data derived from medical records of early detection of cervical cancer in three health centers in East Jakarta district. The number of samples studied was 86 cases and 258 control. The results of this study found that there was a statistically significant association between contraceptive use and the incidence of cervical lesions (p-value <α, where α = 0.05), women who use non-hormonal contraception has 4 times higher risk to have cervical lesions compared with women who never used any contraceptive method, while the risk of women using
hormonal contraception are no different from women who never used a
contraceptive method to have cervical lesions."
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2012
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Maritza Samira
Determinan perilaku wanita usia subur (WUS) dalam deteksi dini kanker serviks di Wilayah Kerja Puskesmas Kelurahan Duri Kepa = Determinants of behavior of women of childbearing age in early detection of cervical cancer in the Work Area Puskesmas Duri Kepa Village in 2024
"Deteksi dini menjadi salah satu upaya penting untuk mencegah terjadinya kanker serviks. Namun, capaian deteksi dini kanker serviks di kota besar seperti Jakarta masih terbilang rendah dan jauh dari target. Capaian deteksi dini kanker serviks di wilayah Puskesmas Kelurahan Duri Kepa pada pertengahan tahun 2024 yaitu 38,75%. Penelitian ini bertujuan untuk mengetahui determinan perilaku wanita usia subur dalam deteksi dini kanker serviks di wilayah kerja Puskesmas Kelurahan Duri Kepa tahun 2024 berdasarkan teori Health Belief Model. Penelitian ini menggunakan pendekatan kuantitatif dengan desain studi cross-sectional. Sumber data penelitian yaitu data primer, menggunakan metode wawancara dengan alat bantu kuesioner. Penelitian dilakukan pada bulan Juli-Agustus 2024 di wilayah kerja Puskesmas Kelurahan Duri Kepa. Sampel dalam penelitian merupakan wanita usia subur 15-49 tahun yang sudah menikah, berjumlah 160 orang yang diambil dengan teknik quota sampling. Hasil penelitian menunjukkan wanita usia subur yang melakukan deteksi dini kanker serviks hanya 20,6%. Secara statistik didapatkan ada hubungan yang signifikan antara usia (p value = 0,029), pendidikan (p value = 0,000), persepsi kerentanan (p value = 0,000), persepsi keseriusan (p value = 0,000), persepsi manfaat (p value = 0,000), persepsi hambatan (p value = 0,000), isyarat bertindak (p value = 0,000), dan efikasi diri (p value = 0,000) dengan perilaku wanita usia subur dalam deteksi dini kanker serviks. Disarankan agar puskesmas mendukung peran fungsi kader, memperkuat KIE kanker serviks, memperluas jangkauan penyebaran informasi dengan pemanfaatan media sosial dan media interaktif yang mudah diakses, dan menjalin kerja sama dengan tokoh yang dianggap berpengaruh oleh masyarakat.
Early detection is one of the important efforts to prevent cervical cancer. However, the achievement of early detection of cervical cancer in big cities like Jakarta is still low and far from the target. The achievement of early detection of cervical cancer in the Duri Kepa Village Health Center area in mid-2024 was 38.75%. This study aims to determine the determinants of behavior of women of childbearing age in early detection of cervical cancer in the working area of Puskesmas Duri Kepa Village in 2024 based on the Health Belief Model theory. This research uses a quantitative approach with a cross-sectional study design. The research data source is primary data, using the interview method with questionnaire tools. The research was conducted in July-August 2024 in the work area of the Puskesmas Duri Kepa Village. The sample in the study was married women of childbearing age 15-49 years, totaling 160 people with quota sampling technique. The results showed that women of childbearing age who performed early detection of cervical cancer were only 20.6%. Statistically there was a significant relationship between age (p value = 0.029), education (p value = 0.000), perceived vulnerability (p value = 0.000), perceived seriousness (p value = 0.000), perceived benefits (p value = 0.000), perceived barriers (p value = 0.000), cues to action (p value = 0.000), and self-efficacy (p value = 0.000) with the behavior of women of childbearing age in early detection of cervical cancer. The results suggest that the puskesmas should support the role of cadres, strengthen cervical cancer IEC, expand the reach of information dissemination by utilizing social media and interactive media that are easily accessible, and collaborate with figures who are considered influential by the community."
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2024
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UI - Skripsi Membership  Universitas Indonesia Library
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