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Lies Dewi Nurmalia
"ABSTRAK
Latar Belakang Biomarker dapat digunakan untuk memprediksi derajat keparahan trauma kepala Tujuan Mengetahui hubungan antara kadar S100B dengan derajat keparahan trauma kepala dan kelainan CT scan kepala Metode Penelitian Penelitian potong lintang di IGD RSUPN Cipto Mangunkusumo RSUP Fatmawati dan RS Permata Cibubur selama Juli Desember 2015 Subjek adalah anak usia 1 18 tahun yang mengalami trauma kepala dengan onset

ABSTRACT
Background Biomarker has ability to predict the severity of TBI and abnormal CT scan Objectives To determine the association between S100B level with the severity of pediatric TBI and intracranial injury Methods A cross sectional study at Emergency Department of RSUPN Cipto Mangunkusumo RSUP Fatmawati and Permata Cibubur Hospital on July December 2015 Subjects were 1 18 year old children with TBI onset within 24 hours before admission We measured SKG score serum S100B level and performed cranial CT scan if indicated Results Twenty subjects had mild TBI and 18 subjects had moderate TBI were included S100B levels were higher in children with moderate TBI as compared to children with mild TBI 0 173 0 054 0 812 g L vs 0 067 0 039 0 084 g L p;Background Biomarker has ability to predict the severity of TBI and abnormal CT scan Objectives To determine the association between S100B level with the severity of pediatric TBI and intracranial injury Methods A cross sectional study at Emergency Department of RSUPN Cipto Mangunkusumo RSUP Fatmawati and Permata Cibubur Hospital on July December 2015 Subjects were 1 18 year old children with TBI onset within 24 hours before admission We measured SKG score serum S100B level and performed cranial CT scan if indicated Results Twenty subjects had mild TBI and 18 subjects had moderate TBI were included S100B levels were higher in children with moderate TBI as compared to children with mild TBI 0 173 0 054 0 812 g L vs 0 067 0 039 0 084 g L p;Background Biomarker has ability to predict the severity of TBI and abnormal CT scan Objectives To determine the association between S100B level with the severity of pediatric TBI and intracranial injury Methods A cross sectional study at Emergency Department of RSUPN Cipto Mangunkusumo RSUP Fatmawati and Permata Cibubur Hospital on July December 2015 Subjects were 1 18 year old children with TBI onset within 24 hours before admission We measured SKG score serum S100B level and performed cranial CT scan if indicated Results Twenty subjects had mild TBI and 18 subjects had moderate TBI were included S100B levels were higher in children with moderate TBI as compared to children with mild TBI 0 173 0 054 0 812 g L vs 0 067 0 039 0 084 g L p;Background Biomarker has ability to predict the severity of TBI and abnormal CT scan Objectives To determine the association between S100B level with the severity of pediatric TBI and intracranial injury Methods A cross sectional study at Emergency Department of RSUPN Cipto Mangunkusumo RSUP Fatmawati and Permata Cibubur Hospital on July December 2015 Subjects were 1 18 year old children with TBI onset within 24 hours before admission We measured SKG score serum S100B level and performed cranial CT scan if indicated Results Twenty subjects had mild TBI and 18 subjects had moderate TBI were included S100B levels were higher in children with moderate TBI as compared to children with mild TBI 0 173 0 054 0 812 g L vs 0 067 0 039 0 084 g L p"
Fakultas Kedokteran Universitas Indonesia, 2016
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Hendra Samanta
"Latar Belakang. Cedera kepala merupakan salah satu masalah kesehatan masyarakat yang serius yang dapat menyebabkan kematian, kecacatan fisik dan kecacatan mental. Cedera kepala dapat menyebabkan sel astrosit rusak sehingga mengeluarkan protein S 100B yang dapat dideteksi didalam darah perifer, sehingga dapat dipakai untuk memprediksi tingkat keparahan cedera kepala yang terjadi. Penelitian ini bertujuan untuk mencari hubungan antara kadar protein S 100B dengan tingkat keparahan cedera kepala.
Metode. Desain penelitian adalah potong lintang untuk mengetahui kadar protein S 100B pada pasien cedera kepala akut onset kurang dari 24 jam. Subyek penelitian sejumlah 85 pasien yang datang berobat ke Instalasi Gawat Darurat RSCM sejak bulan maret ? juni 2015. Dilakukan penilaian GCS, lamanya tidak sadarkan diri, lamanya amnesia pasca trauma dengan bantuan alat TOAG, pemeriksaan CT Scan dan pemeriksaan serum protein S 100B.
Hasil. Didapatkan kadar rerata protein S 100B serum 0,77 μg/L, rerata durasi amnesia 21,22 jam, rerata nilai GCS 13. Terdapat perbedaan kadar protein S 100B pada CKR (rerata 0,4175) dibandingkan dengan pada CKS dan CKB (1,0722) (p=0,020), nilai titik potong kadar protein S 100B pasien yang meninggal 0,765 μg/L (p= 0,002).
Simpulan. Kadar rerata protein S 100B pada cedera kepala ringan lebih rendah dibandingkan dengan kadar protein S 100B pada cedera kepala sedang dan berat, semakin tinggi kadar protein S 100B akan semakin tidak baik keluaran pasien cedera kepala.

Background. Traumatic brain injury is still a serious community health problem can cause death, physical and mental disability. Protein S 100B release from destructive astrocyte from brain injury and detected in the peripheral blood, so that protein S 100B can serve as predictor of severity traumatic brain injury. This research aimed to find association between protein S 100B with traumatic brain injury severity.
Method. This was a cross sectional study focusing to protein S 100B value from acute traumatic brain injury patients with onset < 24 hours. Eighty five patients were recruited from emergency room RSCM. GCS value, duration of post traumatic amnesia with TOAG tools, duration loss of consciousness, brain CT scan and concentration serum protein S 100B were record.
Results. The mean concentration serum Protein S 100B were 0.77, mean PTA duration were 21,22 hours, and the mean GCS were 13. There is a significant differentiation value of concentration protein S 100B from mild trumatic brain injury compare moderate and severe traumatic brain injury (p=0,020), cut off point for death patients was 0,765 μg/L.
Conclusion. The mean serum Protein S 100 B from mild trumatic brain injury lower than moderate and severe traumatic brain injury higher consentration of protein S 100B have bad outcome.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Lies Dewi Nurmalia
"ABSTRAK
Latar Belakang. Biomarker dapat digunakan untuk memprediksi derajat keparahan trauma kepala.
Tujuan. Mengetahui hubungan antara kadar S100B dengan derajat keparahan trauma kepala dan kelainan CT scan kepala.
Metode Penelitian. Penelitian potong lintang di IGD RSUPN Cipto Mangunkusumo, RSUP Fatmawati, dan RS Permata Cibubur selama Juli-Desember 2015. Subjek adalah anak usia 1-18 tahun yang mengalami trauma kepala dengan onset <24 jam. Setiap subjek dilakukan pemeriksaan skor Skala Koma Glasgow Pediatrik, pemeriksaan CT scan kepala bila terdapat indikasi, serta pemeriksaan kadar S100B dari serum.
Hasil Penelitian. Subjek penelitian terdiri atas 20 subjek trauma kepala ringan dan 18 subjek trauma kepala sedang. Hasil penelitian menunjukkan terdapat perbedaan bermakna kadar S100B kelompok trauma trauma kepala sedang dan kepala ringan; median (rentang) 0,173 (0,054-0,812) μg/L dibandingkan 0,067 (0,039-0,084) μg/L, p<0,001. Selain itu juga terdapat perbedaan bermakna antara kelompok yang terdapat kelainan CT scan kepala dibandingkan dengan yang tidak ada kelainan; 0,124 (0,051-0,812) μg/L dan 0,067 (0,039-0,084) μg/L, p=0,001. Berdasarkan analisis ROC, kadar S100B serum sangat kuat untuk memprediksi trauma kepala sedang (AUC 0,818, p=0,001 dan IK95% 0,668-0,969) dengan nilai cut-off 0,083 μg/L.
Simpulan. Kadar S100B serum pada trauma kepala sedang secara bermakna lebih tinggi dari trauma kepala ringan serta memiliki kemampuan diskriminasi sangat baik untuk memprediksi derajat keparahannya.

ABSTRACT
Background. Biomarker has ability to predict the severity of TBI and abnormal CT scan.
Objectives. To determine the association between S100B level with the severity of pediatric TBI and intracranial injury.
Methods. A cross-sectional study at Emergency Department of RSUPN Cipto Mangunkusumo, RSUP Fatmawati, and Permata Cibubur Hospital on July- December 2015. Subjects were 1-18 year-old children with TBI, onset within 24 hours before admission. We measured Pediatric GCS score, serum S100B level, and performed cranial CT scan if indicated.
Results. Twenty subjects had mild TBI and 18 subjects had moderate TBI were included. S100B levels were higher in children with moderate TBI as compared to children with mild TBI; 0,173 (0,054-0,812) μg/L vs 0,067 (0,039-0,084) μg/L, p<0,001. S100B levels were significantly elevated in children following TBI with abnormal cranial CT scan as compared to children with a normal CT scan (0,124 (0,051-0,812) μg/L vs 0,067 (0,039-0,084) μg/L, p=0,001). AUC for S100B was also significant (0,818, p=0,001, CI95% 0,668-0,969) as prediction of moderate TBI with cut-off point 0,083 μg/L.
Conclusions. Children with moderate TBI had significantly higher S100B levels as compared to children with mild TBI. Cut-off point S100B level at 0,083 μg/L has good ability to predict the severity of TBI.
"
Depok: Fakultas Kedokteran Universitas Indonesia, 2016
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Farid Yudoyono
"[ABSTRAK
Latar Belakang: Cedera otak traumatika akibat kecelakaan lalu lintas masih merupakan salah satu penyebab kematian dan kecacatan utama pada kelompok usia produktif. Cedera otak sekunder dideskripsikan sebagai konsekuensi gangguan fisiologis, seperti iskemia, reperfusi, dan hipoksia pada area otak yang beresiko, beberapa saat setelah terjadinya cedera awal (cedera otak primer). Cedera otak sekunder sensitif terhadap terapi dan proses terjadinya dapat dicegah dan dimodifikasi. Metode: Penelitian kohort retrospektif dengan data primer rekam medis. Data yang terdiri dari beberapa variabel yang dikumpulkan secara retrospektif dari catatan medis pasien. RS. Hasan Sadikin, Bandung Jawa Barat, Indonesia. Pengambilan data dilakukan pada 2011-2014. Jumlah sampel yang diambil sebanyak 647 pasien. Analisis yang dilakukan meliputi analisis univariat, bivariat, dan analisis multivariate cox proportional hazard dengan model matematis yang
selanjutnya akan dibuat model skoring. Analisis roctab digunakan untuk menentukan nilai cut-off setiap variabel numerik. Hasil: Variabel perdarahan otak, tingkat kesadaran, dan edema serebri merupakan
faktor resiko outcome, sedangkan variabel peningkatan tekanan intrakranial, kadar elektrolit natrium dan klorida, serta terapi diuretik merupakan faktor resiko untuk terjadinya outcome kematian pada pasien ensefalitis anak. Berdasarkan hasil analisis multivariat skoring didapatkan urutan faktor prognostik yang dominan menyebabkan kematian, yaitu Variabel usia memilik HR sebesar 1,00, natrium
mempunyai HR 0,8, Perdarahan otak pada CT Scan kepala mempunyai HR sebesar 1,73, edema serebri mempunyai HR 2,53, hipoksia mempunyai HR sebesar 2,13, farktur maksillofascial mempunyai HR sebesar 0,6, hipotensi memiliki HR 0,7 dan pembedahan/trepanasi mempunyai HR 0,388 Berdasarkan analisis tersebut maka natrium, GCS, hipotensi, pembedahan dan MFS fraktur merupakan faktor proteksi outcome sedangkan usia, perdarahan otak pada CT Scan, edema serebri, hipoksia merupakan faktor resiko terjadinya outcome
kematian pada pasien cedera kepala berat. Dari hasil mulitvariat yang telah dilakukan sebelumnya apabila skor -69 s/d -47 mengalami resiko rendah untuk mengalami kematian, skor -46 s/d -20 mengalami resiko sedang untuk terjadinya kematian dan skor >-19 akan mengalami resiko tinggi terjadinya kematian. Kesimpulan: Model skoring prognosis yang telah terbentuk ini mampu memprediksi sebesar 84,75 % faktor faktor yang berhubungan dengan prognosis cedera otak traumatika berat. Apabila ada 100 pasien cedera kepala berat dengan adanya semua variabel maka 76 pasien akan meninggal dan bila 100 pasien
cedera kepala berat tanpa adanya semua variabel maka 25 pasien akan meninggal.

ABSTRACT
Background: Severe traumatic brain injury caused by traffic accidents is still one of the major causes of death and disability in the productive age group. Secondary brain injury is described as a physiological disorders, such as ischemia, reperfusion, and hypoxia in brain areas at risk, some time after the initial injury (primary brain injury). Secondary brain injury is sensitive to therapy it can be preventable and modifiable.
Methods: This cohort study with primary data medical records. The data consists of multiple variables collected retrospectively from patient medical records at Hasan Sadikin Hospital Bandung West Java, Indonesia. Data were collected in 2011-2014. The number of samples was 647 patients. Analysis was conducted on univariate, bivariate, and multivariate Cox proportional hazards analysis with a mathematical model which would then be created scoring models. Roctab analysis
is used to determine the cut-off value of any numeric variable.
Results: Variable brain hemorrhage, level of consciousness and cerebral edema is a risk factor outcomes, while variable increased intracranial pressure, electrolyte levels of sodium and chloride, as well as diuretic therapy is a risk factor for the occurrence of mortality outcomes in patients with severe traumatic brain injury. Based on the results of the multivariate analysis of prognostic factors scoring sequence obtained the dominant cause of death, the age variable having an HR of 1.00, sodium has HR 0.8, brain hemorrhage on CT scan head has a HR of 1.73, had a cerebral edema HR 2,53, hypoxia has a HR of 2.13, fracture maxillofascial have HR of 0.6 and hypotension have HR 0.7, surgery / trepanation HR 0.388, based on the analysis of the sodium, GCS, hypotension, MFS fracture, surgery and outcome protection factor whereas age, brain hemorrhage on a CT scan, cerebral edema, hypoxia is a risk factor for mortality outcomes in patients with severe head injury. From the results multivariate analysis has score of -69 s/d -47
experiencing low risk to experience death, a score of -46 s / d -20 experiencing moderate risk for the occurrence of death and a score of > -19 will experience a high risk of death. Conclusions: This Prognostic model scoring has capable to predict 84.75% factors related to the prognosis of severe traumatic brain injury. If there were 100 patients with severe traumatic brain injury in the presence of all variables and 76 patients will die and when 100 patients with severe traumatic brain injury in the absence of all variables that 25 patients will die., Background: Severe traumatic brain injury caused by traffic accidents is still one
of the major causes of death and disability in the productive age group. Secondary
brain injury is described as a physiological disorders, such as ischemia,
reperfusion, and hypoxia in brain areas at risk, some time after the initial injury
(primary brain injury). Secondary brain injury is sensitive to therapy it can be
preventable and modifiable.
Methods: This cohort study with primary data medical records. The data consists
of multiple variables collected retrospectively from patient medical records at
Hasan Sadikin Hospital Bandung West Java, Indonesia. Data were collected in
2011-2014. The number of samples was 647 patients. Analysis was conducted on
univariate, bivariate, and multivariate Cox proportional hazards analysis with a
mathematical model which would then be created scoring models. Roctab analysis
is used to determine the cut-off value of any numeric variable.
Results: Variable brain hemorrhage, level of consciousness and cerebral edema is
a risk factor outcomes, while variable increased intracranial pressure, electrolyte
levels of sodium and chloride, as well as diuretic therapy is a risk factor for the
occurrence of mortality outcomes in patients with severe traumatic brain injury.
Based on the results of the multivariate analysis of prognostic factors scoring
sequence obtained the dominant cause of death, the age variable having an HR of
1.00, sodium has HR 0.8, brain hemorrhage on CT scan head has a HR of 1.73,
had a cerebral edema HR 2,53, hypoxia has a HR of 2.13, fracture maxillofascial have HR of 0.6 and hypotension have HR 0.7, surgery / trepanation HR 0.388,
based on the analysis of the sodium, GCS, hypotension, MFS fracture, surgery
and outcome protection factor whereas age, brain hemorrhage on a CT scan,
cerebral edema, hypoxia is a risk factor for mortality outcomes in patients with
severe head injury. From the results multivariate analysis has score of -69 s/d -47
experiencing low risk to experience death, a score of -46 s / d -20 experiencing
moderate risk for the occurrence of death and a score of > -19 will experience a
high risk of death.
Conclusions: This Prognostic model scoring has capable to predict 84.75%
factors related to the prognosis of severe traumatic brain injury. If there were 100
patients with severe traumatic brain injury in the presence of all variables and 76
patients will die and when 100 patients with severe traumatic brain injury in the
absence of all variables that 25 patients will die]"
Depok: Universitas Indonesia, 2015
T43808
UI - Tesis Membership  Universitas Indonesia Library
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Achmanto Mendatu
Yogyakarta: Panduan, 2010
616.852 1 ACH p
Buku Teks SO  Universitas Indonesia Library
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Mischa Indah Mariska
"[ABSTRAK
Penelitian ini dilakukan untuk mengetahui efektivitas terapi Resource Development and Installation (RDI) dengan Pendulation Exercise pada anak perempuan usia 12 tahun yang mengalami Developmental Trauma. RDI dilakukan dengan menggunakan protokol dasar RDI untuk anak yang dibuat oleh Korn dan Leeds (2002) untuk membangkitkan resource positif. Setelah itu dilakukan Pendulation Exercise untuk memroses pengalaman traumatik berupa perceraian orangtua yang menjadi sumber munculnya perilaku agresif pada anak. Tujuan dari terapi RDI adalah untuk membangkitkan resource guna membentuk positive cognition yang akan bermanfaat untuk mengubah negative cognition. Hasil dari intervensi menunjukkan penurunan perilaku agresif. Penurunan perilaku agresif ini menjadi bukti bahwa telah terjadi pemrosesan informasi yang adaptif. Hal tersebut nampak dari penurunan skor Child Behavioral Checklist (CBCL) pada area permasalahan perilaku agresif. Selain itu orangtua dan partisipan juga melaporkan bahwa partisipan sudah lebih mampu mengontrol perilaku saat marah.

ABSTRACT
This study is done to explain the effectiveness of Resource Development and Installation (RDI) with Pendulation Exercise in a 12 year old girl with Developmental Trauma. RDI is done using RDI basic protocol for children made by Korn and Leeds (2002) to activate positive resources. The other technique is using Pendulation exercise to process the traumatic experience: parental divorce as a source of aggressive behavior. The goal of RDI therapy is to activate the resources and install them for the adaptive information processing, and change the negative cognition into positive cognition. The result of this therapy is the reduction of aggressive behavior. The reduction of aggressive behavior reflects that there has been an adaptive information processing. Participant indicates behavioral changes that were reflected in the Child Behavioral Checklist (CBCL) scores. Parent and participant also report that participant was able to successfully control the anger., This study is done to explain the effectiveness of Resource Development and
Installation (RDI) with Pendulation Exercise in a 12 year old girl with
Developmental Trauma. RDI is done using RDI basic protocol for children made
by Korn and Leeds (2002) to activate positive resources. The other technique is
using Pendulation exercise to process the traumatic experience: parental divorce
as a source of aggressive behavior. The goal of RDI therapy is to activate the
resources and install them for the adaptive information processing, and change the
negative cognition into positive cognition. The result of this therapy is the
reduction of aggressive behavior. The reduction of aggressive behavior reflects
that there has been an adaptive information processing. Participant indicates
behavioral changes that were reflected in the Child Behavioral Checklist (CBCL)
scores. Parent and participant also report that participant was able to successfully
control the anger.]"
Depok: Fakultas Psikologi Universitas Indonesia, 2015
T44156
UI - Tesis Membership  Universitas Indonesia Library
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Hophoptua NM
"Latar Belakang : Cedera kranioserebral ada 2, yaitu cedera primer dan sekunder. PatofisioIogi cedera sekunder yang kompleks menyebabkan perlunya parameter tambahan untuk menilai perburukan klinis penderita cedera kranioserebral. Pada penelitian terdahulu didapat suatu hubungan antara kadar interleukin 6 serum dengan keluaran cedera kranioserebral. Dimana semakin tinggi kadar 11-6 akan semakin buruk keluaran cedera kranioserebral. Dengan melihat hal ini kami melakukan penelitian untuk mengeksplorasi hubungan antara kadar M-6 dengan penderita ceders kranioserebral.
Objektif : Mengetahui peranan IL-6 pada kondisi klinis penderita cedera kranioserebral 5KG 6-12
Desain dan Metode: Observasional dengan repeated measurement design sesuai dengan kriteria seleksi dan dieksplorasi apakah terdapat hubungan IL-6 dengan SKG hari 1,3,7 atau mortalitas.
Hasil : 63 penderita cedera kranioserebral SKG 6-12 dalarn 24 jam dari onset. Semua pasien dilakukan pemeriksaan IL-6 serum dan DPL rutin, Nilai rerata IL-6 tertinggi adalah pada SKG 6 508,938 ± 98,125 dan nilai rerata terendah adalah 11,725 ± 8,441. Dengan uji kai kuadarat didapati hubungan semakin tinggi nilai IL-6 semakin rendah nilai SKG (p<0,0001). Dengan uji kai kuadrat juga didapati semakin tinggi kadar M-6 semakin tinggi mortalitas (p<0,002).
Kesimpulan : IL-6 dapat dijadikan salah satu prediktor keluaran penderita cedera kranioserebral.

Background : Traumatic brain Injury (TBI) is divided in to primary and secondary injury. Complexities of the pathophysiology of secondary brain injury made additional parameters in to evaluation for observed the worsening effect of those mechanisms. In the current study there is a correlation between IL 6 serum concentration and the outcome of TBI. The higher 1L6 would be markedly worsening outcome. Based on this concept, we make the research to explore the correlation between IL 6 concentration and TBI patient.
Objective: To explore the rule of IL 6 on the worsening clinical condition of the TBI patient GCS 6-8 and GCS 9-12.
Design and methods: Observational study with repeated measurement design due to selection criteria and being explored whether any correlation between IL 6 and GCS on day 1,3,7 or mortality.
Results: 63 TBI patients with GCS 6-12 and the onset are 24 hours enrolled to this study. All the patient had IL 6 serum and routine blood test. The highest mean of IL 6 is 508,938 + on GCS 6 and the lowest mean is 11,725 + 8,441 on GCS 12. Result of the chi square test showed there was correlation the higher IL 6 and the lower GCS (p<0,0001). The other analyzed the chi square test showed there were also correlation between the higher IL 6 and mortality (p<0,002).
Conclusion : IL- 6 could be used as one of TBI outcome predictor.
"
Depok: Universitas Indonesia, 2005
T58482
UI - Tesis Membership  Universitas Indonesia Library
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Kamila Puspita
"Traumatic Brain Injury merupakan penyebab kematian utama dan morbiditas pada pasien dengan trauma kepala. Dikarenakan Traumatic Brain Injury mempunyai angka prevalensi yang sangat tinggi dan mortalitas yang tinggi, maka perlu suatu alat bantu berupa cedera bagian luar (cedera scalp) untuk ketahui kemungkinan adanya traumatic brain injury yang di sebabkan oleh sebab mati pada mayat tersebut.
Penelitian ini menggunakan desain studi cross sectional analitik. Sampel dalam penelitian ini berupa data sekunder yang diambil dari laporan pemeriksaan mayat pada Departemen Forensik RS Cipto Mangunkusumo yang memenuhi kriteria inklusi dan eksklusi bejumlah 100 sampel. Data yang diambil berupa umur, jenis kelamin, cedera scalp, fraktur tulang tengkorak, perdarahan epidural, perdarahan subdural, perdarahan serebral didata dari hasil pemeriksaan luar dan pemeriksaan dalam.
Dari penelitian ini didapatkan bahwa tidak ada hubungan yang bermakna antara cedera scalp dengan traumatic brain injury dengan nilai p sebesar 0,09. Hal ini menguatkan teorinya bahwa hanya gold standard yang bisa mendiagnosis adanya traumatic brain injury, yaitu pemeriksaan dalam pada otopsi.

Traumatic Brain Injury is the leading cause of death and morbidity in the world. Due to a very high prevelance rate of traumatic brain injury, a diagnostic tool that is able to quickly identify the presence of traumatic brain injury is needed. Injuries to the scalp can be used as a diagnostic tool to determine the presence of Traumatic Brain Injury.
This study uses an analytical cross sectional study design. The sample in this research wassecondary data taken from autopsy reports to the Department of Forensic Cipto Mangunkusumo that meet the inclusion and exclusion criteria, which was 100 samples. Data taken the form of age, gender, scalp injury, brain bone fracture, epidural hemorrhage, subdural hemorrhage, cerebral hemorrhage recorded from external examination results and examination.
From this study it was found that there was no significant correlation between scalp injury with traumatic brain injury with p value of 0.09. It supported the theory that only internal autopsy can diagnose the presence of traumatic brain injury.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
S-Pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Khusnul Khatimah
"ABSTRAK
Penelitian ini berusaha mengetahui peran faktor keluarga, melalui tingkat family functioning dan family hardiness terhadap keterkaitan antara paparan kejadian traumatik (traumatic exposure) dengan posttraumatic growth melalui analisis moderated-mediation pada penyintas bencana alam gempa bumi dan likuifaksi di PASIGALA. Partisipan yang didapatkan adalah 122 orang penyintas berusia 17-35 tahun (M = 21.541, SD = 4.936) yang merupakan penyintas likuifaksi PASIGALA secara primer atau langsung. Hasil yang didapatkan menunjukkan bahwa tingkat family hardiness sedang hingga tinggi memberikan efek positif terhadap keberfungsian keluarga sehingga menjadi fungsional meskipun mengalami beberapa paparan kejadian traumatik. Namun, keberfungsian keluarga yang diperkuat oleh family hardiness tidak menjadikan individu dapat mencapai posttraumatic growth yang lebih tinggi meskipun family hardiness berperan penting dalam menjadikan keluarga berfungsi dengan baik. Secara praktis, hasil mengarahkan agar program trauma healing yang mendukung tercapainya posttraumatic growth sebaiknya berfokus pada aspek personal penyintas, seperti perbedaan paparan kejadian yang dialami. Tetapi, program untuk membantu keluarga dapat berfungsi dengan baik kembali (healthy) setelah melalui krisis kebencanaan dapat dilakukan dengan berfokus pada membantu keluarga membentuk karakter yang hardy.

ABSTRACT
This study discusses the role of the family, through family functioning and family hardiness on the relationship between the reporting of traumatic events (traumatic exposure) with posttraumatic growth through moderated-mediation analysis in survivors of Earthquake and Liquefaction disaster in PASIGALA. Participants obtained were 122 individuals (17-35 years old, M = 21.541, SD = 4.936) who were primary survivors of PASIGALA liquefaction. The results obtained indicate that the mean and higher level of family hardiness have a positive effect on moderating the negative effect of traumatic exposure to the family functioning. However, family functioning supported by family hardiness does not make individuals able to achieve higher post-traumatic growth indirectly although it is an important factor for helping family to function well. These lead to encouraging social workers in helping survivors, to focus on their personal aspect, such as degree of traumatic exposures. However, helping family as a whole to be well-functioning after disaster also could be conducted, by focusing on building characteristics of hardy family."
Depok: Fakultas Kedokteran Gigi Universitas Indonesia, 2020
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Farhan Hary Arafah
"Introduction: Traumatic Brain Injury (TBI) is a common non-infectious disease. It is so common that it is dubbed as the “silent pandemic”. It is also the main contributor of the overall disability and mortality rates in the overall injuries caused by trauma. Studies have found that the annual worldwide TBI occurrence is 295 occurrences for every 100,000 people. Another study found that around 10 million people suffer from TBI which requires hospitalization or with lethal consequences annually worldwide. Several factors can influence the overall outcome of TBI in patients. This study aims to elucidate the influence some of these factors may have; including age, sex, severity, amount of lesion, and brain region affected. Methods: This research is an analytical research using retrospective methods as medical records from the archives of the Department of Neurology of FKUI-RSCM is used. Statistical analysis is done using SPSS with Chisquared and Kruskal-Walis as the main method of statistical tests used; appropriate to data type. Results: Age was found to be a significant factor in the development of worse outcomes in the 14th day post-trauma (p= 0.026). Severity was found to be a significant factor also regardless of when the GOSE score was taken (14th day p= 0.004, 30th day p= <0.001, 90th day p=<0.001). Injuries in multiple brain regions was also a significant factor (14th day p= 0.003, 30th day p= 0.037, 90th day p= 0.008). The parietal region was found to be the only significant predictor (14th day p= 0.013, 30th day p= 0.011, 90th day p= 0.044). Conclusion: Age, severity, amount of brain region affected, and injury in the parietal region is a significant outcome predictor.

Introduksi: Cedera Otak Traumatik (COT) adalah penyakit non-infeksius yang umum ditemui. Sangat sering hingga dianggap sebagai “pandemi diam-diam”. COT juga merupakan kontributor Tingkat Disabilitas dan Mortalitas utama dari semua cedera traumatik lainnya. Satu studi telah menemukan bahwa kejadian COT tahunan pada seluruh dunia adalah 295 kejadian untuk setiap 100.000 orang. Study lain menemukan sekitar 10 juta orang menderita COT yang memerlukan perawatan di rumah sakit atau berakibat fatal tiap tahunnya di seluruh dunia. Ada beberapa faktor yang dapat mempengaruhi keluaran keseluruhan pasien COT. Studi ini bertujuan untuk menjelaskan pengaruh dari beberapa faktor tersebut; termasuk umur, jenis kelamin, keparahan, jumlah lesi, dan area otak yang terpengaruhi. Methode: Penelitian ini adalah penelitian analitik dengan metode retrospektif dengan menggunakan rekam medis yang tersedia pada arsip Departemen Neurologi FKUI-RSCM. Analisis statistik dilaksanakan menggunakan SPSS dengan metode Chi-Squared dan Kruskal Walis sebagai metode statistik utama yang dipakai dan sesuai dengan tipe data juga. Hasil: Umur ditemukan sebagai faktor yang signifikan dalam perkembangan hasil kurang baik pada hari ke-14 sehabis trauma (p=0.026). Keparahan juga ditemukan sebagai faktor yang signifikan pada tiap titik waktu skor GOSE diambil (hari ke-14 p= 0,004, hari ke-30 p= <0,001, hari ke-90= <0,001). Cedera pada lokasi multipel pada otak juga ditemukan sebagai faktor yang signifikan (hari ke-14 p= 0.003, hari ke-30 p= 0.037, hari ke-90 p= 0.008). Daerah parietal juga ditemukan sebagai prediktor yang signifikan (hari ke-14 p= 0,013, hari ke-30 p= 0,011, hari ke-90 p= 0,044). Konklusi: Umur, keparahan dan jumlah daerah otak yang terpengaruhi dan cedera pada daerah parietal adalah prediktor hasil yang signifikan."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
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UI - Tugas Akhir  Universitas Indonesia Library
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