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"Insomnia dikarakterisasikan dengan keluhan subjektif mengenai ketidakpuasan terhadap kualitas dan durasi tidur, kesulitan untuk menginisiasi tidur pada jam tidur, atau terbangun di tengah malam. Pengobatan herbal efektif dalam mengatasi gangguan tidur karena mengandung senyawa aktif yang memiliki efek sedatif hipnotik. Tujuan dari penelitian ini yaitu untuk merancang produk herbal yang membantu meringankan gangguan sulit tidur, menganalisis market dalam negeri maupun luar negeri produk serupa, menganalisis kompetitor produk sejenis, membuat rencana branding produk dan membuat rencana marketing produk. Hasil yang didapat adalah bahan aktif dalam rancangan produk obat herbal ini terdiri dari Valerianae radix extract (Akar Valerian), Myristica frograns semen extract (Biji Pala), Curcumae domestica extract (Kunyit), Alyxia reinwardtii extract (Kulit Pulasari), Foeniculum vulgare extract (Adas), Anacardium occidentale (Daun jambu mete). Masing-masing bahan aktif herbal ini mempunyai zat aktif yang memiliki aktivitas hipnotik sedatif, sehingga bermanfaat untuk mengatasi insomnia. Berdasarkan analisa pasar, total penjualan produk serupa menurut data IQVIA 2021 adalah sebesar Rp25,786,851,721 dan juga kompetitor pada produk herbal serupa masih minim sehingga membuat peluang bisnis untuk produk herbal ini sangat besar. Berdasarkan tinjauan produksi, PT. Indofarma memiliki kapasitas untuk memproduksi obat herbal. Rencana branding dan marketing akan menggunakan marketing ATL serta BTL untuk meningkatkan penjualan produk.

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Insomnia is characterized by subjective complaints of dissatisfaction with sleep quality and duration, difficulty initiating sleep at bedtime, or waking up in the middle of the night. Herbal medicine is effective in overcoming sleep disorders because it contains active compounds that have a sedative-hypnotic effect. The purpose of this research is to design herbal products that help relieve insomnia, analyze domestic and foreign markets for similar products, analyze competitors for similar products, make product branding plans and make product marketing plans. The results obtained are that the active ingredients in the design of this herbal medicinal product consist of Valerianae radix extract (Valerian root), Myristica frograns semen extract (Nutmeg Seed), Curcumae domestica extract (Turmeric), Alyxia reinwardtii extract (Pulasari peel), Foeniculum vulgare extract ( Fennel), Anacardium occidentale (Cashew leaves). Each of these herbal active ingredients has an active substance that has sedative-hypnotic activity, making it useful for treating insomnia. Based on market analysis, total sales of similar products according to IQVIA 2021 data amounted to IDR 25,786,851,721 and also competitors for similar herbal products are still minimal, making the business opportunities for these herbal products very large. Based on the production review, PT. Indofarma has the capacity to manufacture herbal medicines. The branding and marketing plan will use ATL and BTL marketing to increase product sales."

"[ABSTRAKPeningkatan jumlah lansia di perkotaan setiap tahunnya menimbulkan masalah kesehatan pada lansia, sehingga diperlukannya pelayanan keperawatan masyarakat akan kebutuhan lansia. Masalah yang ditemukan pada lansia yang tinggal di Sasana salah satunya adalah insomnia. Karya ilmiah ini akan membahas terkait Nenek A dengan insomnia. Praktik klinik selama 7 minggu dimana peneliti melakukan terapi non farmakologis dalam mengatasi insomnia di Sasana Tresna Werdha Budi Mulia 1 DKI Jakarta yang bertujuan menganalisis insomnia dengan intervensi back massage dan terapi musik. Pitssburgh Sleep Quality Index bernilai 11 interpretasi kualitas tidur buruk. Intervensi yang diberikan dalam waktu 4 minggu dengan back massage dan musik terapi selama ± 45 menit seminggu 2 kali pertemuan saat memberikan massage dan musik terapi didukung menciptakan suasana yang kondusif dan menjaga privasi, penggunaan baby oil untuk massage, dan tehnik massage yang tidak terlalu kuat serta memperhatikan kondisi kulit lansia, serta handscoons sebagai pelindung diri merupakan hal yang mendukung dalam pelaksanaan. Hasil dari intervensi back massage dan musik terapi yang mampu menginisiasi tidur pada klien dan PSQI menurun bernilai 7. Perawat STW diharapkan kedepannya dapat memberikan intervensi pada lansia yang insomnia sehingga dapat meningkatkan kemampuan perawat dalam memberikan terapi secara non farmakologi.

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ABSTRACTAn increase of geriatric in urban areas will be cause health problems in the geriatric, so the urband areas need public health nursing. Problems were founded in the geriatric who live in Sasana one of which is insomnia . Related scientific papers will discuss about Nenek A with insomnia. Clinical practice for 7 weeks in which researchers performed non pharmacological therapies in treating insomnia in Sasana Tresna Werdha 1 Budi Mulia Jakarta that aims to analyze the intervention of insomnia with a back massage and music therapy. Pitssburgh Sleep Quality Index (PSQI) score 11 interpretation poor sleep quality. Intervention is given within 4 weeks with a back massage and music therapy for ± 45 minutes a week 2 meetings while giving massage and music therapy supported creating a conducive atmosphere and maintain privacy, the use of baby oil to massage, and massage techniques that are not too strong and attention elderly skin conditions, as well as personal protective handscoons is supporting the implementation. Results of the intervention back massage and music therapy capable can initiating sleep to client and PSQI after intervention score 7. Nurses STW decline is expected in the future be able to provide intervention in elderly insomnia that can improve the ability of nurses in providing non-pharmacological therapy.;An increase of geriatric in urban areas will be cause health problems in the geriatric so the urband areas need public health nursing Problems were founded in the geriatric who live in Sasana one of which is insomnia Related scientific papers will discuss about Nenek A with insomnia Clinical practice for 7 weeks in which researchers performed non pharmacological therapies in treating insomnia in Sasana Tresna Werdha 1 Budi Mulia Jakarta that aims to analyze the intervention of insomnia with a back massage and music therapy Pitssburgh Sleep Quality Index PSQI score 11 interpretation poor sleep quality Intervention is given within 4 weeks with a back massage and music therapy for 45 minutes a week 2 meetings while giving massage and music therapy supported creating a conducive atmosphere and maintain privacy the use of baby oil to massage and massage techniques that are not too strong and attention elderly skin conditions as well as personal protective handscoons is supporting the implementation Results of the intervention back massage and music therapy capable can initiating sleep to client and PSQI after intervention score 7 Nurses STW decline is expected in the future be able to provide intervention in elderly insomnia that can improve the ability of nurses in providing non pharmacological therapy , An increase of geriatric in urban areas will be cause health problems in the geriatric so the urband areas need public health nursing Problems were founded in the geriatric who live in Sasana one of which is insomnia Related scientific papers will discuss about Nenek A with insomnia Clinical practice for 7 weeks in which researchers performed non pharmacological therapies in treating insomnia in Sasana Tresna Werdha 1 Budi Mulia Jakarta that aims to analyze the intervention of insomnia with a back massage and music therapy Pitssburgh Sleep Quality Index PSQI score 11 interpretation poor sleep quality Intervention is given within 4 weeks with a back massage and music therapy for 45 minutes a week 2 meetings while giving massage and music therapy supported creating a conducive atmosphere and maintain privacy the use of baby oil to massage and massage techniques that are not too strong and attention elderly skin conditions as well as personal protective handscoons is supporting the implementation Results of the intervention back massage and music therapy capable can initiating sleep to client and PSQI after intervention score 7 Nurses STW decline is expected in the future be able to provide intervention in elderly insomnia that can improve the ability of nurses in providing non pharmacological therapy ]"

"Buku yang berjudul "New guide to medicines & drugs" ini dipersembahkan oleh The British Medical Association. Buku ini berisikan panduan mengenai obat-obatan."

"ABSTRAKLatar belakang : Insomnia merupakan gangguan tidur yang sering dialami pascatraumakepala, tetapi faktor yang berhubungan dengan insomnia belum banyak diketahui.Penelitian ini bertujuan mengetahui prevalensi insomnia pascatrauma kepala dan faktoryang berhubungan.Metode penelitian: Desain penelitian potong lintang deskriptif menggunakan PittsburghSleep Quality Index (PSQI) versi Bahasa Indonesia pada pasien pascatrauma kepala diPoliklinik Neurologi RSUPN Ciptomangunkusumo, RSUD Pasar Rebo dan RSPADGatot Soebroto selama bulan Maret-Mei 2016 dengan onset minimal tiga bulan. Faktoryang dianalisis adalah derajat keparahan trauma kepala, gambaran CT-Scan kepala,derajat nyeri kepala, gangguan depresi dan ansietas. Derajat keparahan trauma kepaladinilai berdasarkan skala koma Glasgow, lamanya pingsan, lamanya amnesiapascatrauma dan CT-Scan kepala. Insomnia ditetapkan jika skor PSQI >8. Nyeri kepaladinilai dengan numeric rating scale, gangguan depresi dan ansietas dinilai dengan MiniInternasional Neuropsychiatric Interview Version ICD-10 (MINI ICD-10).Hasil : Diantara 70 orang subjek pascatrauma kepala, didapatkan prevalensi insomniasebesar 33%. Subjek cedera kepala berat (31%) memiliki risiko 3,4 kali mengalamiinsomnia dibandingkan cedera kepala ringan (42%) (IK 95% 1,072-10,806). Subjekdengan nyeri kepala sedang sampai berat (26%) memiliki risiko 5,78 kali mengalamiinsomnia dibandingkan subjek tanpa nyeri sampai nyeri kepala ringan (74%) (IK 95%1,730-19,315). Tidak didapatkan hubungan antara gangguan depresi (9%), ansietas (3%)dengan insomnia.Kesimpulan : Insomnia banyak dijumpai pascatrauma kepala. Keluhan nyeri kepalasedang sampai berat, dan cedera kepala berat merupakan faktor yang berhubungandengan insomnia

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ABSTRACTBackground : Insomnia is very common following traumatic brain injury (TBI), but therelated factors with insomnia is less known. This study was aimed to determine theprevalence of insomnia after TBI and related factors.Methods : Cross-sectional descriptive study using Pittsburgh Sleep Quality Index (PSQI)Indonesian version on patients with history of TBI, with a minimum of three months sinceonset, in Neurology clinic of Cipto Mangunkusumo general hospital, Pasar Rebo generalhospital and Gatot Soebroto Army hospital during March-May 2016. The analyzedfactors consisted of: severity of TBI, head CT-Scan findings, severity of headache,depression, and anxiety disorders. Severity of TBI was assessed on Glasgow coma scale,duration of loss of consciousness, duration of post traumatic amnesia and head CT-Scanfindings. Insomnia was determined if PSQI score > 8. Severity of headache was measuredby numeric rating scale, depression and anxiety disorders were assessed based on MiniInternasional Neuropsychiatric Interview Version ICD-10 (MINI ICD-10).Results : Prevalence of insomnia among 70 subjects after TBI was 33%. Severe TBIsubjects (31%) had 3.4 times the chance of developing insomnia compared to mild cases(42%) (CI 95% 1.072-10.806). Moderate-severe headache subjects (26%) had 5.78 timesthe risk of having insomnia compared to no headache-mild headache cases (74%) (CI95% 1.730-19.315). No significant relation could be established between depression(9%), anxiety disorders (3%) with insomnia.Conclusion : Insomnia is common after TBI. Moderate-severe headache and severe TBIare the related factors of insomnia."

"ABSTRAKPenelitian ini dilakukan untuk melihat insomnia yang terjadi pada mahasiswa melalui pendekatan pengaruh kecemasan tes. Hal ini menjadi penting bagi mahasiswa karena pada mahasiswa yang memiliki kecemasan tes yang tinggi, maka mahasiswa tersebut dapat mengalami insomnia. Penelitian ini berdasarkan teori yang telah dikemukakan oleh Eysenck yang mengatakan bahwa ketegangan atau kecemasan yang tinggi dapat membuat konsentrasi belajar terhambat, sehingga mahasiswa tersebut dapat menderita insomnia. Pemakaian model pada penelitian ini dikarenakan konstruk kecemasan tes memiliki indikator-indikator yang tidak dapat diukur atau diamati secara langsung, maka dilakukan dengan uji model struktural. Subyek dalam penelitian ini berjumlah 167 orang. Dari hasil perhitungan dengan LISREL dengan analisis Goodness of Fit (GOF), didapat hasil Chi-Square yang cukup besar 1958.91 (p=0.0). Artinya model yang menggambarkan adanya pengaruh kecemasan tes terhadap insomnia pada mahasiswa yang sedang dalam masa ujian tidak sesuai dengan data.

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ABSTRACTThe research has been done to study Insomnia among college students based on effect of test anxiety model. This study becomes important to college student because there is a possibility of insomnia among college student who have test anxiety. This study based on Eysenck?s theory who mentioned that high anxiety may distract the concentration for studying, even can make insomnia for some college students. The construct of test anxiety have indicator which can?t be direct observed, therefore researcher used structural equation modeling. The participants of this research are 167 college students. The analysis with Goodness of Fit (GOF), that have Chi-Square result 1958.91 (p=0.0). This result indicates model who have describe there is influence test anxiety to insomnia at college student does not fit with the data."

"[ABSTRAKDynamic Capabilities Theory (DC) merupakan teori yang menjelaskan untukmendapatkan keunggulan daya saing, perusahaan tidak hanya dengan memilikisumber daya yang istimewa, melainkan harus disadari dengan kemampuanperusahaan dalam mengintegrasi dan menggunakan sumber daya tersebut. Salahsatu kemampuan dalam Dynamic Capabilities Theorya dalah kemampuanpemasaran. Penelitian ini membahas pengaruh kemampuan pemasaran yangdilakukan pada dVisi sepeda motor PT. Suzuki IndoMobil Motor yang terdiri darikemampuan market sensing, kemampuan customer relationship management(CRM), dan kemampuan brand management terhadap kinerja pengembanganproduk baru (NPD). Dengan bantuan analisis structural equation modeling (SEM)didapatkan hasil bahwa market sensing tidak memiliki hubungan langsung yangsignifikan, sedangkan kemampuan CRM dan kemampuan brand managementmemiliki hubungan langsung yang signifikan, selain itu kemampuan marketsensing juga memoderasi CRM dan brand management terhadap kinerjapengembangan produk baru dan didapatkan hasil signifikan, dan hubunganmoderasi CRM terhadap hubungan brand management terhadap kinerjapengembangan produk baru dan didapatkan hasil signifikan. Dengan demikian,Suzuki diharapkan meningkatkan kemampuan pemasarannya agar dapatmeningkatkan kinerja perusahaan dalam mengembangkan produk baru demikelangsungan bisnis kedepannya.

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ABSTRACTDynamic Capabilities Theory (DC) is a development of resource based view(RBV) theory. Although having excellent human resource may help gettingsignificant profit and competitive advantage, a company has to understand how tointegrate and empower the resource well. One of capabilities based on DynamicCapabilities Theory is marketing capabilities. This research aimed to determinemarketing capabilities on motorcycle division at PT Suzuki Indomobil Motor. Thisresearch consists of market sensing capability, customer relationshipmanagement (CRM) capability and brand management capability on performanceof new product development. Analysis using structural equation modelingrepresent that market sensing has no significant and direct relationship to theperformance of new product development, while CRM and brand managementcapability has significant and direct relationship to the performance of newproduct development, besides market sensing capability moderates relationshipbetween CRM and brand management to performance of new productdevelopment with significant value, moderation of CRM to brand managementrelationship to performance of new product development has significant value.According to the result of study, Suzuki is expected to increase the companyperformance in developing new product by increasing marketing capabilities forfuture business continuity., Dynamic Capabilities Theory (DC) is a development of resource based view(RBV) theory. Although having excellent human resource may help gettingsignificant profit and competitive advantage, a company has to understand how tointegrate and empower the resource well. One of capabilities based on DynamicCapabilities Theory is marketing capabilities. This research aimed to determinemarketing capabilities on motorcycle division at PT Suzuki Indomobil Motor. Thisresearch consists of market sensing capability, customer relationshipmanagement (CRM) capability and brand management capability on performanceof new product development. Analysis using structural equation modelingrepresent that market sensing has no significant and direct relationship to theperformance of new product development, while CRM and brand managementcapability has significant and direct relationship to the performance of newproduct development, besides market sensing capability moderates relationshipbetween CRM and brand management to performance of new productdevelopment with significant value, moderation of CRM to brand managementrelationship to performance of new product development has significant value.According to the result of study, Suzuki is expected to increase the companyperformance in developing new product by increasing marketing capabilities forfuture business continuity.]"

"Implementasi dokumentasi merupakan hal yang wajib dilakukan disetiap industri farmasi, termasuk PT. Medifarma Laboratories. PT. Medifarma Laboratories merupakan industri farmasi yang bergerak sebagai toll—manufacturer, yaitu sebagian besar produknya di ekspor ke luar negeri. Hal ini membuat dokumentasi menjadi hal penting dalam memenuhi persyaratan Cara Pembuatan Obat yang Baik (CPOB). Namun PT. Medifarma Laboratories belum memiliki dokumentasi yang baik. Hal ini berkaitan dengan belum adanya lembar kerja mengenai analisis pengembangan produk baru, seperti pada produk Sangobion Capsule Reformulation, sehingga seluruh kegiatan analisis produk tersebut tidak terdokumentasi. Laporan praktik kerja ini bertujuan untuk membuat lembar kerja (worksheet) evaluasi untuk uji analitik dan fisik agar CPOB di PT. Medifarma Laboratories dapat diaplikasikan dengan baik. Kedua lembar kerja dibuat sesuai ketentuan CPOB serta dibuat dengan kolom yang dapat diisi apabila hasil telah disetujui, ditandatangani, dan diberi tanggal oleh pihak yang berwenang. Hal ini sudah sesuai dengan peraturan yang berlaku di PT. Medifarma Laboratories. Lembar kerja yang akan digunakan secara konsisten ini dapat membantu memastikan keamanan dan kualitas produk sehingga memperkecil risiko kesalahan pelaksanaan oleh analis laboratorium.

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Implementation of documentation is something that must be done in every pharmaceutical industry, including PT. Medifarma Laboratories. PT. Medifarma Laboratories is a pharmaceutical industry that operates as a toll manufacturer, meaning that most of its products are exported abroad. This makes documentation important in fulfilling the requirements for Good Medicine Manufacturing Practices (CPOB). However PT. Medifarma Laboratories does not yet have good documentation. This is related to the absence of worksheets regarding the analysis of new product development, such as the Sangobion Capsule Reformulation product, so that all product analysis activities are not documented. This work practice report aims to create an evaluation worksheet for analytical and physical tests for CPOB at PT. Medifarma Laboratories can be applied well. Both worksheets are made in accordance with CPOB regulations and are made with columns that can be filled in if the results have been approved, signed and dated by the authorized party. This is in accordance with the regulations in force at PT. Medifarma Laboratories. This worksheet, which will be used consistently, can help ensure product safety and quality, thereby minimizing the risk of implementation errors by laboratory analysts."

"Praktek Kerja Profesi Apoteker di PT. Kimia Farma (Persero) Tbk Pulo Gadung. bertujuan Mengamati penerapan Cara Pembuatan Obat yang Baik (CPOB) yang dilakukan PT. Kimia Farma, mengamati kegiatan yang dilakukan oleh PT. Kimia Farma, mengamati peranan apoteker dalam industri farmasi sehingga dapat dibandingkan dengan teori yang diperoleh selama masa perkuliahan dan menjadi bekal untuk menghadapi dunia kerja. Seorang apoteker mempunyai peranan dan tanggung jawab penting untuk menerapkan aspek?aspek yang tercantum dalam CPOB tersebut, antara lain sebagai penanggung jawab produksi, penanggung jawab pengawasan dan pemastian mutu. Tugas khusus yang diberikan berjudul kajian validasi pembersihan pada produksi sediaan kapsul di PT. Kimia Farma Plant Jakarta.Tugas khusus ini bertujuan menentukan produk marker dari sediaan kapsul yang diproduksi oleh PT. Kimia Farma Plant Jakarta, menentukan nilai MACO dari produk yang terpilih, menentukan batas nilai swab pada prosedur validasi pembersihan alat yang digunakan pada produksi sediaan kapsul, membuat validasi metode analisis residu dari produk terpilih, serta membuat protokol validasi pembersihan dari protokol terpilih. Berdasarkan hasil perhitungan diperoleh data yaitu produk marker dari sediaan kapsul adalah Nitrokaf Retard yang berisi gliseriltrinitrat 2,5 mg. Nilai MACO terkecil berdasarkan kriteria dosis terapi yaitu 0.0088 mg. Batas nilai swab sebesar 7x10-8 mg/swab.

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Apothecary Internship at PT. Kimia Farma (Persero) Tbk. Pulogadung. Observing intended application of Good Manufacturing Practice Medicine (GMP) conducted by PT. Kimia Farma, observe the activities performed by the PT. Kimia Farma, studying the role of pharmacists in the pharmaceutical industry so it can be compared with the theory acquired during the lecture and be equipped to face the world of work. A pharmacist has a role and responsibility for implementing essential aspects listed in the GMP, among others, in charge of production, responsible for oversight and quality assurance. Special assignment given titled was cleaning validation studies on the production of capsule dosage in PT. Kimia Farma Plant Jakarta.

Special assignment aimed to determine the product of the preparation capsule marker produced by PT. Kimia Farma Plant Jakarta, MACO to determine the value of the product selected, set a value on the validation procedures cleaning swab tool used in the production of capsules dosage, making residue analytical method validation of selected products, as well as making cleaning validation protocols of the selected protocol. Based on calculations from the data obtained by the product of the preparation marker is Nitrokaf Retard capsules containing 2.5 mg gliseriltrinitrat. MACO smallest values based on criteria that therapeutic doses of 0.0088 mg. Limit value of 7x10-8 swab mg / swab."