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Rumah Sakit Kusta Sungai Kundur yang berdiri sejak tahun 1914 merupakan rumah sakit pembina dan pusat rujukan penderita kusta se Sumatera dan Kalimantan Barat dengan kapasitas 450 tempat tidur, terletak di kecamatan Banyuasin I desa Mariana, Kabupaten Musi Banyuasin, dengan jarak ± 20 km dari kota Palembang. Mulai tahun 1995 terjadi penurunan kunjungan penderita kusta untuk rawat jalan dan rawat inap sehingga dalam upaya memanfaatkan sarana dan prasarana dan sumber daya manusia, berdasarkan surat dari Dirjen. Yan. Med. No. BM.01.03.3.2.04929.A tanggal 31 Oktober 1995, RS Kusta Sungai Kundur telah mendapat izin untuk memberikan pelayanan umum. Akan tetapi pemanfaatan pelayanan pada poliklinik umum oleh masyarakat di kecamatan Banyuasin I masih rendah, dimana angka kunjungan sampai dengan tahun 2001 hanya berkisar ± 15 - 16 orang/hari. Oleh karena itu penelitian ini dilakukan untuk memperoleh informasi faktor-faktor yang berhubungan dengan rendahnya pemanfaatan pelayanan di poliklinik umum tersebut. Jenis penelitian dilakukan menurut analisis kuantitatif dengan pendekatan cross sectional dengan menggunakan metode wawancara dan kuesioner. Pengisian kuesioner telah dilakukan uji validitas dan reliabilitas dimana hasilnya adalah valid dan reliabel. Metode analisis yang digunakan adalah analisis univariat, bivariat dengan Chi Square dan multivariat dengan regresi logistik. Hasil penelitian menyimpulkan masih rendahnya rata-rata pemanfaatan yaitu 54,3 %, faktor internal yang bermakna yang berhubungan dengan pemanfaatan adalah variabel sarana prasarana dan tarif, sedangkan faktor eksternal adalah variabel pengetahuan dan pekerjaan, dan faktor dominan adalah variabel sarana prasarana. Kesimpulan dari penelitian ini bahwa sarana prasarana yang baik berhubungan signifikan untuk meningkatkan pelayanan di poliklinik RSKSK dengan peluang 4,137 kali dibandingkan dengan sarana prasarana yang kurang baik. Dari penelitian ini disarankan beberapa upaya yang dapat dilakukan untuk meningkatkan pemanfaatan pelayanan di poliklinik RSKSK antara lain : memenuhi kebutuhan alat kesehatan, alat kedokteran, alat rumah tangga sesuai dengan jenis pelayanan yang diberikan. Selain itu memenuhi kebutuhan ruangan pelayanan sehingga dapat memberikan kenyamanan kepada pasien, serta menciptakan lingkungan yang sehat. ......An Analytical Approach on the Health Services Sungai Kundur Hospital at Banyuasin in the Year 2003The Sungai Kundur Hospital for Leper which founded in 1914 is designed to become the center of leprosy treatment and research for Sumatera and West Kalimantan. Built with 450 people capacity it was located in Banyuasin C desa Mariana region, Musi Banyuasin regency, 20 km from Palembang. Since 1995 there has been a decrease in the amount of leper patient that treated at the Hospital. In order to use the exceed man power and supra-infrastructure, the Sungai Kundur Hospital for Leper has been authorized to give public service to the common people. A letter from Dirjen Yan Med No. BM 01.03.3.2.04929.A posted in 31 October 1995 has legalized it. Not with standing the man power, infrastructure and suprastructure that available, people that had been using the health service provided by Sungai Kundur Hospital are still modest, with only ± 15 - 16 people a day. Therefore this research had been done to acquire information about the factor that related to the issue. The research has been done according to quantitative analytics with cross sectional approach using interview and questioner method. The questioner had been tested to make sure there are both valid and reliable. Analytic methods that had been used are univariant, bivariant with Chi Square and multi variant with logistic regression. The research conclude that the low used of public service (that is 54, 3 %) had been caused by internal factors with supra-infrastructure and tariff variable, external factors with knowledge and occupation variable, dominant factors with supra-infrastructure variable. In conclusion of this research suffice to say that adequate supra-infrastructure had significant effects to increase public health care service in Sungai Kundur Hospital with a chance 4,137 to inadequate supra-infrastructure. The research suggested there are some paths that can be used to increase the health service in Sungai Kundur Hospital for Leper. Which are: fulfilling the necessities of adequate equipment for health care and other equipment that also needed to perform service to the community (equipment that depends on the service). Not to forget giving a comfort of a service room to the patient and creating a healthy environment.

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Persamaan gender antar perawat dengan pasein kanker ginekologi, menyebabkan perawat merefleksikan kejadian yang dialami pasien terhadap dirinya. Sehingga ada makna tersendiri yang perawat rasakan selama merawat pasien kanker ginekologi. Tujuan penelitian ini mengetahui makna merawat pasien kanker ginekologi bagi perawat perempuan. Penelitian ini menggunakan studi fenomenologi deskriptif dengan wawancara mendalam terhadap lima orang partisipan yang dipilih secara purposive sampling. Data dianalisis menggunakan analisis Colaizzi dan di dapatkan delapan tema. Secara umum perawat merasa bersyukur diberikan kesehatan sebagai bentuk makna yang didapat selama merawat pasien kanker ginekologi. Hasil penelitian ini menyarankan agar perawat lebih bersikap caring terhadap pasien dan himbawan kepada perempuan untuk melakukan papsmear sebagai upaya deteksi dini kanker ginekologi.

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Gender equality among nurses and their patients with gynecologic cancer made nurses reflect on the events experienced by the patients toward her, so that nurses felt a special meaning when treating patient with gynecologic cancer. The purpose of this study is to determine the meaning of caring patients with gynecologic cancer. This study used a descriptive phenomenological study of in-depth interviews with five participants who selected by purposive sampling. Data were analyzed using analysis Colaizzi and get eight themes. In general, nurses feel grateful for given health as a form of meaning which they obtained while caring patients with gynecologic cancer. The results of these study are to suggest nurses to give more caring towards their patients and suggest women to do pap smear as an early detection of gynecologic cancer.

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Tujuan Penelitian ini bertujuan menilai adanya perubahan kadar mikronutrien besi folat zinc dan selenium pada wanita hamil setelah pemberian multivitamin dan multimineral Metode Wanita hamil trimester 1 yang melakukan antenatal care di poliklinik Fetomaternal Rumah Sakit Cipto Mangunkusumo periode Juli hingga Oktober 2011 masuk sebagai subjek penelitian Intervensi dilakukan dengan memberikan multivitamin dan mineral yang dikonsumsi 1 tablet perhari selama 3 bulan Pengukuran kadar besi folat zinc dan selenium serum sebelum dan sesudah pemberian multivitamin dan multimineral menjadi keluaran penelitian Analisis statistik menggunakan uji T berpasangan dan uji Wilcoxon Hasil Sebanyak 28 wanita hamil trimester 1 yang bersedia ikut dalam penelitian dan menjalani pemeriksaan kadar mikronutrien sebelum dan sesudah pemberian multivitamin dalam periode penelitian Sebelum pemberian multivitamin kadar besi dan zinc di bawah normal kadar selenium dalam batas normal dan kadar folat di atas normal Pasca suplementasi multivitamin dan multimineral kadar zinc di bawah normal kadar besi dan selenium dalam batas normal dan kadar folat di atas normal Didapat penurunan kadar zinc dan peningkatan kadar folat pasca suplementasi yang bermakna secara statistik p 0 009 p 0 003 Didapat penurunan kadar besi dan peningkatan kadar selenium yang tidak bermakna secara statistik p 0 295 p 0 333 Kesimpulan Terdapat penurunan kadar zinc dan peningkatan kadar folat pasca suplementasi multivitamin dan multimineral Kata Kunci Mikronutrien suplementasi multivitamin dan multimineral

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Abstract Objective To measure changes of serum iron folate zinc and selenium level on pregnant woman after multi micronutrient supplementationMethod First trimester pregnant woman whom attended Maternal Fetal Policlinic at Cipto Mangunkusumo Hospital from July 2011 till October 2011 was considered into the study The intervention was consumption of multi micronutrient tablet once a day for three months period Measurements of serum level of iron folate zinc and selenium before and after supplementation were our outcomes We used paired T Test and Wilcoxon test for statistical analysis Results We had a total of 28 pregnant women of first trimester whom participated in the study and had measurement of micronutrient serum level before and after supplementation during the time period Before supplementation Serum iron and zinc level were below normal Serum selenium level was normal with higher than normal serum folate level After supplementation serum zinc level was found to be below normal Both level of serum iron and selenium increased to normal Serum folate level was higher than normal We found a decrease of serum zinc level with an increase in serum folate level that was statistically significant p 0 009 p 0 003 respectively We found slight decrease of serum iron level and an increase of serum selenium level that were not statistically significant p 0 295 p 0 333 Conclusion There is a decreased level of serum zinc with an increase in serum folate level after multi micronutrient supplementationKeywords Multi micronutrient supplementation

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Latar belakang: Prematuritas merupakan salah satu kelainan yang masih menjadi masalah global. Kejadian prematuritas tidak hanya terjadi di negara berkembang tetapi juga di negara maju. Beberapa kondisi ibu hamil dapat memicu keadaan hipoksia dalam rahim sehingga menyebabkan kelahiran prematur. Keadaan plasenta menggambarkan kesejahteraan janin intra uteri. Kondisi hipoksia seluler memicu ekspresi HIF-1α yang menjadi faktor transkripsi bagi CA9 sebagai penanda hipoksia. Penelitian ini bertujuan menganalisis pengaruh hipoksia terhadap plasenta prematur. Metode: Sampel menggunakan plasenta prematur yang hipoksia (H) dan nonhipoksia (N) sebagai kontrol. Parameter yang dinilai adalah struktur histologis plasenta (Hematoksilin-Eosin), regulator hipoksia HIF-1α (imunohistokimia), dan penanda hipoksia CA9 (ELISA). Hasil: Penilaian struktur histologis menunjukkan adanya perbedaan jumlah pembuluh darah fetus antara kedua kelompok secara bermakna, dimana pada kelompok hipoksia jumlah pembuluh darah fetus lebih banyak dibandingkan kelompok non-hipoksia. Distribusi intensitas ekspresi HIF-1α kedua kelompok juga berbeda bermakna. Rerata kadar CA9 kedua kelompok tidak berbeda bermakna, namun terdapat kecenderungan rerata kadar CA9 kelompok hipoksia lebih tinggi 28% dibandingkan yang non-hipoksia. Kesimpulan: Pengaruh hipoksia terhadap plasenta prematur pada tingkat molekuler berupa stabilitas protein HIF-1α yang menyebabkan peningkatan jumlah pembuluh darah fetus dan terjadi kecenderungan peningkatan sintesis protein CA9.

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ABSTRACT
Background: Prematurity is a disorder that is still a global problem. Incidence of prematurity is a problem in developing and also in developed countries. Certain condition accompanying pregnancies may trigger uterine hypoxia, causing premature birth. The placental condition is related with the intra-uterine fetal condition. Cellular hypoxic condition caused by systemic chronic hypoxia, lead to stabilization of HIF-1α protein, a transcription factor of CA9. This study aimed to analyze the effect of hypoxia on the premature placenta. Methods: Samples from hypoxic premature placenta (H) and non-hypoxic premature placenta (N) were collected. Parameters assessed were histological structure of the placenta (Hematoxylin-Eosin), expression of HIF-1α (immunohistochemistry) and the level of CA9 (ELISA). Results: Assessment of histological structure showed the number of fetal blood vessels were differed significantly between the two group, wherein the hypoxia group was more than the non-hypoxia. The distributions of HIF-1α expression between the two groups were also differed significantly. The average level of CA9 between two groups were not significant, but there is a tendency of higher level of CA9 in the hypoxia group (28% higher compared to the non-hypoxia group). Conclusion: It is concluded that the effect of the hypoxia on premature placenta in this study occured at molecular level and lead to HIF-1α protein stability that causes an increase of the number of fetal blood vessel and synthesis of CA9 protein.;Background: Prematurity is a disorder that is still a global problem. Incidence of prematurity is a problem in developing and also in developed countries. Certain condition accompanying pregnancies may trigger uterine hypoxia, causing premature birth. The placental condition is related with the intra-uterine fetal condition. Cellular hypoxic condition caused by systemic chronic hypoxia, lead to stabilization of HIF-1α protein, a transcription factor of CA9. This study aimed to analyze the effect of hypoxia on the premature placenta. Methods: Samples from hypoxic premature placenta (H) and non-hypoxic premature placenta (N) were collected. Parameters assessed were histological structure of the placenta (Hematoxylin-Eosin), expression of HIF-1α (immunohistochemistry) and the level of CA9 (ELISA). Results: Assessment of histological structure showed the number of fetal blood vessels were differed significantly between the two group, wherein the hypoxia group was more than the non-hypoxia. The distributions of HIF-1α expression between the two groups were also differed significantly. The average level of CA9 between two groups were not significant, but there is a tendency of higher level of CA9 in the hypoxia group (28% higher compared to the non-hypoxia group). Conclusion: It is concluded that the effect of the hypoxia on premature placenta in this study occured at molecular level and lead to HIF-1α protein stability that causes an increase of the number of fetal blood vessel and synthesis of CA9 protein., Background: Prematurity is a disorder that is still a global problem. Incidence of prematurity is a problem in developing and also in developed countries. Certain condition accompanying pregnancies may trigger uterine hypoxia, causing premature birth. The placental condition is related with the intra-uterine fetal condition. Cellular hypoxic condition caused by systemic chronic hypoxia, lead to stabilization of HIF-1α protein, a transcription factor of CA9. This study aimed to analyze the effect of hypoxia on the premature placenta. Methods: Samples from hypoxic premature placenta (H) and non-hypoxic premature placenta (N) were collected. Parameters assessed were histological structure of the placenta (Hematoxylin-Eosin), expression of HIF-1α (immunohistochemistry) and the level of CA9 (ELISA). Results: Assessment of histological structure showed the number of fetal blood vessels were differed significantly between the two group, wherein the hypoxia group was more than the non-hypoxia. The distributions of HIF-1α expression between the two groups were also differed significantly. The average level of CA9 between two groups were not significant, but there is a tendency of higher level of CA9 in the hypoxia group (28% higher compared to the non-hypoxia group). Conclusion: It is concluded that the effect of the hypoxia on premature placenta in this study occured at molecular level and lead to HIF-1α protein stability that causes an increase of the number of fetal blood vessel and synthesis of CA9 protein.]

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Kartini-Interogativa dalam Bahasa Arab: Sebuah Analisis Sintaktis. (Di bawah bimbingan Afdol Tharik Wastono, M.Hum., dan Wiwin Triwinarti, MA) Fakultas Sastra Universitas Indonesia 2000. Interogativa bahasa Arab dalam tataran fungsi sintaktisnya dapat diklasifikasikan berdasarkan interogativa fungsional dan interogativa tak fungsional. Dan segi tataran sintaktisnya, interogativa ini dapat dikiasifikasikan berdasarkan kelas kata partikel (huruf) dan kelas kata pronomina (isim), dan dalam kategori gramatikal, sebagian interogativa ini bersifat deklinatif dan sebagian lagi bersifat tak deklinatif (dapat menempati kasus). Berdasarkan tuntutan pertanyaan, interogativa terbagi atas tiga bagian yaitu: a. Interogativa untuk tasawwur dan tasdiq, b. Interogativa untuk tasdiq, c. Interogativa untuk tasawwur. Analisis interogativa bahasa Arab ini dilakukan dengan mengemukakan teori-teori yang telah dikemukakan oleh para linguis baik secara linguistik umum maupun secara linguistik Arab (tradisional dan modern). Setelah teori-teori itu diperoleh, maka analisis dilakukan berdasarkan kerangka teori acuan yang dijadikan acuan analisis.