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Abstrak :
ABSTRACT
BACKGROUND: hypertension remains a global burden. Complications of unrecognized hypertension might increase mortality as shown by a WHO 2013 report that hypertension caused 9.4 million deaths worldwide. There is no prior data in Indonesia on blood pressure status in young adults with similar education levels. Medical students are at high risk of developing early hypertension due to modern lifestyle habits. This study aimed to determine the blood pressure profile of medical students as representative of the young adult population. METHODS: we measured the prevalence of hypertension in medical students. All medical students who agreed to participate completed a questionnaire. Afterwards, we conducted a physical examination and obtained blood and urine samples to screen for blood pressure, estimated glomerular filtration rate, and the lipid profile. RESULTS: the prevalence of students with prehypertension or hypertension was 29.6%. The mean eGFR was 105.45 ml/min/m2. The mean total cholesterol was within normal limits. CONCLUSION: the prevalence of hypertension in medical students was high. This study shows that early detection of hypertension is key to treating it early and therefore to reducing morbidity and mortality.

Abstrak :
ABSTRAK
Lupus nephritis (LN) is involvement of the kidney in patient with systemic lupus erythematosus (SLE) and one of the most common target organ in SLE. The diagnosis of LN will significantly impact the clinical outcome and therapy of the patient. Therapy regiment of LN is divided into two stages, induction and maintenance treatment. The main objective of the induction therapy is to achieve complete or partial remission as soon as possible since it is correlated with better prognosis and fewer relapse incidence. In the maintenance stage, the main aim of the therapy is to maintain the remission status and avoid future relapse. It is also important to evaluate the effectiveness of the therapy as it will affect the duration and the regiment therapy being used. Corticosteroid, cyclophosphamide, mycophenolate mofetil, azathrioprine, cyclosporine and tacrolimus are example of drugs used in LN therapy. Currently, studies are being conducted to evaluate and develop targeted drug therapy to further add treatment options for LN.

Abstrak :
ABSTRACT
BACKGROUND: in Indonesia, majority of hemodialysis centers use reusable dialyzer for cost efficiency reason. Currently, there is no available data regarding the quality of life of the end stage-renal disease patient who use reusable dialyzer measured by a standardized questionnaire, as it was stated that at molecular level, reusable dialyzer could worsen leukocyte activity and could affect patients complaints and symptoms. METHODS:this was a retrospective cohort study which involved 39 subjects. All subjects underwent hemodialysis at Cipto Mangunkusumo Hospital. The study was conducted in March - September 2017. All subjects had experienced two kinds of dialyzers, the reusable dialyzers (before 2015) and the single-use dialyzers (after 2015). Of all patients, 19 patients did not know the change of dialyzers. Subjects were interviewed with Kidney Disease Quality of Life-Short Form 36 questionnaire.RESULTS:in kidney disease component dimension, there was a significant mean difference between reusable group (68.74; SD 13.22) and single-use group (74.87; SD 13.54) (Wilcoxon test, p=0.01). The Physical Component Summary dimension, in reusable group was 63.65; SD 27.07 and in single-use group was 69.38; SD 23.07 (Wilcoxon test, p=0.217). The Mental Component Summary dimension, in reusable group was 71.78; SD 21.54 and in single-use group was75.27; SD 22.30 (Wilcoxon test, p=0.127). Bivariate analysis and further analysis showed significant association between income less than 5 million rupiah and low quality of life (p=0.048).CONCLUSION:the reusable dialyzer membrane lowers the ESRD patients quality of life influenced by another factor such as low income.