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"Pendahuluan: Rosela memiliki khasiat antiinflamasi. Ulser merupakan keadaan inflamasi dalam rongga mulut.Tujuan: Menganalisis efektivitas ekstrak etanol terstandar kelopak bunga rosela terhadap penyembuhan ulser.Metode: Penelitian in vivo pada model ulser 12 tikus, dibagi menjadi kelompok kontrol dan perlakuan. Rosela diteteskan 2 kali sehari pada ulser, kemudian hari ke 3 dan 7 dikorbankan. Parameter yang diobservasi adalah kemerahan dan bengkak di sekitar jaringan ulser, diameter ulser, serta skor radang.Hasil: Rosela 7.5% 7 hari dapat menghilangkan kemerahan, sedangkan 3.75% dan 7.5% menurunkan diameter ulser dan skor radang.Kesimpulan: Aplikasi tetes ekstrak terstandar rosela efektif dalam mempercepat penyembuhan ulser.

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Background: Roselle has antiinflammatory effect. Ulcer is an inflammatory condition in oral.Objective: Analyze effectiveness of roselle in healing an ulcer.Methods: This research in vivo on ulcer model 12 rats, divided into control and treatment group. Roselle drops were applied twice a day on ulcer, then day 3 to 7 was sacrificed. Healing process was observed by looking redness and swelling, ulcer diameter, and inflammation score.Results: Roselle 7.5% 7 days can eliminate redness, while 3.75 % and 7.5% reduced ulcer diameter and inflammation score.Conclusion: Application drops of standardized ethanol extract of roselle are effective in ulcer healing."

"Latar Belakang: Rosela dilaporkan memiliki khasiat sebagai antiinflamasi.Tujuan: mengetahui efektivitas rosela terhadap ulser mukosa mulut.Metode: 12 tikus sprague-dawley dibagi dua; kelompok kontrol dan perlakuan. Triamcinolone diaplikasikan pada kelompok kontrol positif, kelompok perlakuan diberikan aplikasi tetes rosela 7.5% dan 15%, selama 3 atau 7 hari.Hasil; Hilangnya kemerahan dan pengurangan diameter ulser pada rosela 7 hari (7.5% dan 15%), hilangnya bengkak pada rosela 7 hari (15%) dan penurunan skor radang pada rosela 3 hari (15%) dan 7 hari (7.5% dan 15%).Kesimpulan: Efektivitas rosela setara Triamcinolone 0.1% pada kemerahan dan penurunan diameter ulser 7 hari.

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Backgrounds: Roselle have effect as anti-inflammatory.Objectives: To determine the effectiveness of roselle towards oral mucosa ulcer.Methods: 12 sprague-dawley rats were divided into 2 groups; control and treatment. triamnicolone as positive control, treatment group was dropped by 7.5% and 15% roselle. Wound healing was observed in the third or seventh day.Results; Redness disappearance and ulcer diameter decrease in seventh days (7.5% and 15%). Swelling disappearance in seventh days (15%). Inflammation score decrease in both third days (15%) and seventh days (7.5% and 15%).Conclusions: roselle is effective for ulcer healing. the Effectiveness is equivalent to Triamcinolone 0.1% in redness disappearance and decreasing of ulcer diameter in seventh days."