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Abstrak :
The aim of this study was to investigate the effect of ant (hypertensive agents with different degrees of renal excretion lisinopril (L) eliminated in the kidney and fosinopril (F), only 50% of which is eliminated through the kidney on renal function in hypertension patients with mild to moderate renal failure. Materials and methods: Patients were divided into two groups. The first group was given F 10 mg/day and the second group was given L 10 mg/day. Groups were divided randomly, and drugs were given for 6 weeks each night at 8.00p.m. The hypertension status of each subject was determined from systolic blood pressureJ140 mmHg or diastolic blood pressure -f 90 mg/dl. Subjects were both male and female, with an age range of 18- 65 years old. Results: The results from the creatinine examination of the 10 mgF group was (3.06 ±0.97) mg/dl after drug use, which showed no decrease in renal function. The difference was insignificant (p=0.17). The 10 mgL group the creatinine level was (3.22 ±0.17), where as in the 10 mg L group the creatinine level was (3.22 ± 0.75) mg/dl before the use of the drug and (4.11 ± 2.14) mg/dl after the use of the drug respectively. There was no worsening of the renal function, which did not differ significantly (p=0.11). There was a significant difference (p < 0.05) in the creatinine level of the 10 mg F and 10 mg L groups. The serum creatinine level before and after treatment did show any significant changes at. 6 week. However, the serum creatinine profile over 6 week was more significant in the F group than in the L groups.

Abstrak :
Angka kejadian penyakit ginjal kronik semakin meningkat dengan tingkat kematian pertahun yang cukup tinggi yang menjadi masalah kesehatan serius di dunia karena mengalami peningkatan insidensi, berdampak pada morbiditas dan mortalitas serta sosial ekonomi dunia termasuk di Indonesia dengan mayoritas penduduk usia produktif angkatan kerja pada industri manufaktur. Oleh karena itu diperlukan deteksi dini penurunan fungsi ginjal dan faktor yang mempengaruhinya. Penelitian ini merupakan penelitian potong lintang analitik dengan pendekatan kuantitatif menggunakan data sekunder MCU PJK3 tahun 2022 dengan total data penelitian sebanyak 2.304 data. kemudian dilakukan analisis terhadap data-data yang telah dikumpulkan. data-data tersebutmencakup jenis kelamin, usia, sulit BAK, ISK, penyakit ginjal, BSK, inkontinensia urin, hipertensi, diabetes, klas alkohol, klas merokok, klas olahraga, klas TD, klas IMT, klas GDP, lemak, urinalisa, sindrom metabolik, jenis manufaktur, lama kerja, suhu panas, suhu dingin, beban kerja tidak sesuai dengan waktu dan jumlah pekerjaan, duduk lama >4 jam terus menerus, posisi tubuh tidak ergonomis, eLFG. Hasil penelitian didapatkan bahwa terjadi penurunan fungsi ginjal (Laju Filtrasi Glomerolus /LFG <90 ml /menit /1,73 m2) sebesar 33,8% dari total pekerja industri manufaktur di Jawa Barat pada tahun 2022. Penurunan eLFG dipengaruhi faktor risiko individu, klinis dan pekerjaan. Kesimpulannya faktor risiko yang berpengaruh terhadap kejadian penurunan fungsi ginjal pada pekerja industri manufaktur di Jawa Barat pada tahun 2022 adalah jenis kelamin laki-laki, usia lebih dari 40 tahun, kondisi hipertensi derajat I dan II, kondisi obesitas dan lama masa kerja lebih dari 19 tahun, dengan faktor berpengaruh yang paling dominan adalah jenis kelamin laki-laki. ......The incidence of chronic kidney disease is increasing with a fairly high annual death rate which is a serious health problem in the world because it has increase incidence, has an impact on morbidity and mortality as well as a serious socio-economic world including in Indonesia with the majority of the working age population in the manufacturing industry. Therefore an early detection of decreased kidney function and factors that influence it become necessity. This research is an analytical quantitative research with a cross sectional design using secondary data of MCU in PJK3 in 2022 with total 2.304 data. The data includes gender, age, UTI, renal disease, bladder stone,, incontinentia urine, hypertention, DM, alcohol class, smoking class, exercise class, BP class, BMI class, fasting glucose class, lipid, urinalysis, metabolic syndrome, manufacture type, working periodes, heat temperature, cold temperature, workload not matched the time and ammount of work, prolong seating >4 hours continuously, un ergonomic body position, eGFR. The result of the study suggest there was a decrease in kidney function (Glomerolar Filtration Rate /GFR <90 ml /minute /1,73 m2) of 33,8% of the total manufacturing industry workers in West Java in 2022. The decreased of eGFR are influenced by individual, clinical and occupational risk factors. The conclusion, risk factor that influence the incidence of renal impairment in manufacture industry workers in West Java in 2022 are male, age over 40 years old, condition of hypertention grade I and II, obesity and periodes of work of more than 19 years, with the most dominant influence factor is male gender.

Abstrak :
[ABSTRAK
Keluarga yang merawat anak dengan gagal ginjal kronik terutama yang mendapat terapi hemodialisis memiliki masalah. Penelitian ini bertujuan untuk mengeksplorasi pengalaman keluarga dalam merawat anak gagal ginjal kronik yang mendapat terapi hemodialisis. Metode penelitian ini menggunakan pendekatan fenomenologi deskriptif dengan cara wawancara mendalam kepada 7 partisipan. Partisipan adalah keluarga yang merawat anak selama minimal 1 bulan terakhir dan sedang menjalani terapi hemodialisis di RSUPN Cipto Mangunkusumo Jakarta. Data dianalisis dengan menggunakan teknik Collaizi dan menghasilkan 5 tema, yaitu 1) respon keluarga terhadap perawatan anak, 2) strategi koping yang dibangun keluarga, 3) dampak merawat anak bagi keluarga,, 4) upaya dukungan sosial yang diberikan keluarga, 5) perubahan pada anak yang menjalani terapi hemodialisis menurut persepsi keluarga. Hasil penelitian ini menunjukkan bahwa keluarga yang merawat anak memiliki permasalahan yang kompleks. Hasil penelitian ini diharapkan menjadi informasi dasar untuk mengembangkan program dalam menerapkan asuhan yang berpusat pada keluarga.

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ABSTRACT
Families who care for children with chronic renal failure who received therapy will have vulnerable occurrence problem. This study aim to explore the experience of families in caring for children with chronic renal failure receiving hemodialysis therapy. This research method is using descriptive phenomenological approach with in-depth interviews to 7 participants. Participants are families who care for the child for at least one month past is undergoing hemodialysis therapy in Cipto Mangunkusumo hospital. Data was analyzed by Collaizi so as to obtain 5 themes, namely the family's response to child care, family coping strategy, the impact of child care for families, family support and changes of children undergoing hemodialysis therapy related to family perception. These results indicate that the families who care for children have complex problems. This study endorse to develop program based on familycentered care, Families who care for children with chronic renal failure who received therapy will have vulnerable occurrence problem. This study aim to explore the experience of families in caring for children with chronic renal failure receiving hemodialysis therapy. This research method is using descriptive phenomenological approach with in-depth interviews to 7 participants. Participants are families who care for the child for at least one month past is undergoing hemodialysis therapy in Cipto Mangunkusumo hospital. Data was analyzed by Collaizi so as to obtain 5 themes, namely the family's response to child care, family coping strategy, the impact of child care for families, family support and changes of children undergoing hemodialysis therapy related to family perception. These results indicate that the families who care for children have complex problems. This study endorse to develop program based on familycentered care]

Abstrak :
[ABSTRAK
Hemodialisis merupakan terapi modalitas yang digunakan pada pasien gagal ginjal terminal untuk memperpanjang kehidupan. Tolok ukur keberhasilan dalam memperpanjang kehidupan pasien melihat survival rate. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi Survival rate pada pasien yang mendapatkan terapi hemodialisis dalam 5 tahun. Penelitian ini menggunakan desain analitik korelasi dengan pendekatan retrospektif dan melibatkan 114 orang pasien yang memulai menjalani terapi hemodialisis dari tahun 2010 sampai bulan Juni tahun 2015 saat pengambilan data serta pengumpulan data dilakukan dengan studi dokumentasi melalui laporan harian ruangan hemodialisa. Sebanyak 86,8 % pasien mengalami event. Kepatuhan program hemodialisis dan dosis hemodialisis dapat mempengaruhi survival rate. Pasien yang tidak patuh menjalani program hemodialisis memiliki risiko 4,844 kali mengalami event dan pasien yang tidak sesuai dosis dalam menjalani terapi hemodialisis memiliki risiko 25,188 kali lebih mengalami event. Penelitian ini dapat memberikan dampak positif dalam meningkatkan kuwalitas pelayanan keperawatan khususnya dalam menekan angka event pada pasien yang menjalani terapi hemodialisis sehingga pasien akan survival dengan terapi hemodialisis dan diharapkan pada peneliti selanjutnya untuk melanjutkan penelitian survival rate pada pasien hemodialisis dengan melihat variabel kepatuhan pembatasan cairan dan nutrisi pada pasien hemodialisis.

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ABSTRACT
Hemodialysis is a modality treatment used in patients with terminal renal failure to prolong their lives. Benchmark of success in prolonging lives of patients is indicated by survival rate. This study aimed to identify the factors that influence survival rate in patients receiving hemodialysis therapy within 5 years. This study used analytical correlation with retrospective approach and involving 114 patients from 2010 to June 2015. Data collection was conducted by study documentation through daily reports of hemodialysis unit. Most of patients 86.8% experienced an event. Compliance in hemodialysis program and hemodialysis dose may affect survival rate. Non-adherent patients undergoing hemodialysis had 4.844 times higher risk of experiencing an event. Patients who did not fit in the dose of hemodialysis therapy has 25.188 times higher risk of experiencing an event. This research may have a positive impact in improving the quality of nursing care services, especially in suppressing the number of events in patients undergoing hemodialysis. It is expected that further research to assess variables such as compliance of fluids restriction and nutrition in hemodialysis patients., Hemodialysis is a modality treatment used in patients with terminal renal failure to prolong their lives. Benchmark of success in prolonging lives of patients is indicated by survival rate. This study aimed to identify the factors that influence survival rate in patients receiving hemodialysis therapy within 5 years. This study used analytical correlation with retrospective approach and involving 114 patients from 2010 to June 2015. Data collection was conducted by study documentation through daily reports of hemodialysis unit. Most of patients 86.8% experienced an event. Compliance in hemodialysis program and hemodialysis dose may affect survival rate. Non-adherent patients undergoing hemodialysis had 4.844 times higher risk of experiencing an event. Patients who did not fit in the dose of hemodialysis therapy has 25.188 times higher risk of experiencing an event. This research may have a positive impact in improving the quality of nursing care services, especially in suppressing the number of events in patients undergoing hemodialysis. It is expected that further research to assess variables such as compliance of fluids restriction and nutrition in hemodialysis patients.]

Abstrak :
Diberlakukannya JKN di rumah sakit maka terjadi perubahan sistem pembayaran dari pembayaran secara retrospektif fee for service menjadi sistem pembayaran prospektif INA-CBG rsquo;s Sebagai salah satu fasilitas pelayanan kesehatan, RS RK Charitas mempunyai peranan untuk memberikan pelayanan yang berkualitas namun tetap memperhatikan cost effective pelayanan yang diberikan. Penelitian ini bertujuan untuk menganalisis biaya dan mengidentifikasi faktor-faktor penentu inefisiensi layanan hemodialisis pada pasien gagal ginjal kronik di RS RK Charitas sehingga bisa dijadikan pedoman pengendalian biaya dalam melayani pasien. Jenis penelitian ini bersifat analisis deskriptif dengan menggunakan data primer pengamatan dan wawancara dan data sekunder berupa data dari RS RK Charitas tahun 2016. Analisis biaya menggunakan pendekatan Activity Based Costing ABC dengan metode ldquo;Bottom Up rdquo;. Metode ABC untuk mengalokasikan biaya dengan mengidentifikasi pemicu biaya cost driver penyebab terjadinya biaya layanan hemodialisis. Beban biaya operasional merupakan beban yang terbesar dalam penyelenggaraan layanan hemodialisis. Gaji pegawai merupakan salah satu biaya terbesar dalam biaya operasional. Analisis faktor-faktor penyebab inefisiensi dilakukan dengan perhitungan Value Stream Mapping VSM. Komposisi value added VA dibanding non value added NVA adalah 17.73 :82.27 . Implementasi lean pada layanan hemodialisis dapat mengeliminasi pemborosan.

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Enactment of JKN in hospital changes the payment system from retrospective payment fee for service into prospective payment INA CBG 39 s . As a healthcare facility, RK Charitas Hospital has a role to provide not only quality but also consider cost effective of services. This study aimed to analyze costs and identify the determinants of the inefficiency of hemodialysis services in patients with chronic renal failure at RK Charitas Hospital so that it can be used as guidelines for cost control in serving patients. This is a descriptive analysis research using primary data observations and interviews and secondary data from RK Charitas Hospital in 2016. Approach of cost analysis is Activity Based Costing ABC with Bottom Up method. ABC method is used to allocate costs by identifying cost drivers of hemodialysis services. Operational cost is the biggest expense in the hemodialysis services. Salary of employees is one of the biggest expenses in operational costs. Analysis of the inefficiencie factors uses thecalculation of Value Stream Mapping VSM . The composition of value added VA compared to non value added NVA is 17.73 82.27 . Lean implementation on hemodialysis services could eliminate waste.

Abstrak :
Gagal Ginjal Kronis GGK adalah kondisi penurunan fungsi ginjal yang bersifat ireversibel yang artinya fungsi ginjal tidak dapat kembali seperti semula. Prevalensi penyakit gagal ginjal kronis meningkat setiap tahunnya. Ansietas banyak dialami oleh pasien GGK yang menjalani hemodialisis. Tujuan penelitian adalah mengidentifikasi pengaruh terapi self help group terhadap tingkat ansietas pasien Gagal Ginjal Kronis di Ruang Hemodialisis. Desain penelitian yang digunakan quasy-experimental pre test-post test with control group. Tujuh puluh empat responden terlibat, terbagi menjadi kelompok intervensi dan kelompok kontrol. Hasil penelitian menunjukkan tingkat ansietas pasien menurun dari ansietas berat menjadi sedang, pasien dengan ansietas sedang menjadi ringan, dengan hubungan yang bermakna p = 0,000. Variabel yang berhubungan dengan dengan tingkat ansietas antara lain pekerjaan dan lama menjalani hemodialisis, sedangkan variabel yang tidak berhubungan adalah usia, penghasilan jenis kelamin, pendidikan, status pernikahan p>0,005. Penelitian ini merekomendasikan terapi generalis dan self help group dalam menurunkan tingkat ansietas pasien Gagal Ginjal Kronis di unit hemodialisis. ......Chronic Kidney Failure CKF is a condition of irreversible kidney dysfunction, which means that the kidney function can not go back to normal. The prevalence of chronic renal failure increases every year. Anxiety is experienced by many CKF patients undergoing hemodialysis. The objective of the study was to identify the influence of self help group therapy on the anxiety level of Chronic Kidney Failure patients in Hemodialysis Room. The research design used quasy experimental pre test post test with control group. Seventy four respondents were involved, divided into intervention groups and control groups. The results showed that the patient 39 s anxiety level decreased from severe anxiety to moderate, patients with moderate anxiety to mild anxiety , with significant association p 0.000 . Variables associated with anxiety levels include occupation and duration of hemodialysis, while unrelated variables were age, income, gender, education, marital status. p 0.005. This study recommends generalist therapy and self help group in lowering the anxiety level of Chronic Kidney Failure patients in the hemodialysis unit.

Abstrak :
ABSTRAK
Xerostomia sering dialami pasien Gagal Ginjal Kronis. Masalah ini akan berdampak pada meningkatnya sensasi haus sehingga mempengaruhi pasien untuk meningkatkan asupan cairan yang menyebabkan peningkatan Interdialytic Weight Gain dan berujung pada penurunan Quality of Life pasien. Penelitian ini bertujuan mengetahui perbedaan pengaruh permen karet xylitol dan mouthwash terhadap xerostomia pada pasien gagal ginjal kronis. Desain yang digunakan adalah quasi eksperimen dengan melibatkan 30 orang responden yang dipilih dengan teknik consecutive sampling dan dibagi dalam dua kelompok. Hasil uji General Linear Model menunjukkan tidak ada perbedaan dalam empat pengukuran xerostomia pada kedua kelompok intervensi dengan p-value > 0,05. Disimpulkan bahwa penggunaan permen karet xylitol dan mouthwash memiliki efek yang sama dalam menurunkan keluhan xerostomia pasien gagal ginjal kronis. Hasil penelitan ini dapat direkomendasikan untuk diterapkan sebagai upaya mengatasi xerostomia pada pasien gagal ginjal kronis.

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ABSTRACT
Xerostomia is often experienced by patients with Chronic Renal Failure. This problem will have an impact on increasing thirst sensations that affect the patient to increase fluid intake that leads to an increase Interdialytic Weight Gain and lead to decreased Quality of Life patients. The aim of this research was to know the effect of chewing gum xylitol and mouthwash on xerostomia in chronic renal failure patients. The design was quasi experiment involving 30 respondents selected by consecutive sampling technique and divided into two groups. The results of General Linear Model test showed there was no differences in the four xerostomia measurements in both intervention groups with p-value> 0.05. The conclusion of this research was xylitol chewing gum and mouthwash had same effect to reduce xerostomia in patients with chronic renal failure. The results of this study can be recommended to be applied as an intervention to resolve xerostomia in chronic renal failure patients.

Abstrak :
Latar belakang: Penyakit ginjal kronik PGK masih merupakan masalah kesehatan yang serius pada anak dengan morbiditas yang semakin meningkat dan memiliki dampak terutama pada kualitas hidup anak. Data Riskesdas 2013 menunjukkan prevalens PGK pada penderita ge; 15 tahun di Indonesia sebesar 0,2 . Penelitian di Kuwait melaporkan peningkatan prevalens PGK pada anak dari 188 1996 menjadi 329 per satu juta populasi anak pada tahun 2003. Tujuan: Mengetahui kualitas hidup anak PGK serta hubungannya dengan derajat keparahan, lama diagnosis, dan faktor-faktor yang berhubungan demografi. Metode: Penelitian potong lintang antara Juli 2016-Mei 2017. Subyek penelitian adalah anak berusia 2-18 tahun yang didapatkan secara consecutive sampling dan menggunakan kuesioner baku PedsQL trade; modul generik versi 4.0 yang diisi orangtua dan anak. Hasil: Total subjek adalah 112 anak. Kualitas hidup terganggu didapatkan dari laporan orangtua 54,5 dan laporan anak 56,3 . Fungsi sekolah dilaporkan paling sering terganggu pada laporan anak dan fungsi fisis pada laporan orangtua. Faktor yang berhubungan dengan kualitas hidup adalah lama diagnosis >60 bulan p=0,004 , jenis kelamin perempuan p=0,019 , dan jenjang pendidikan menengah p=0,003. Simpulan: Lebih dari separuh anak PGK menurut orangtua 54,5 dan anak 56,3 memiliki gangguan kualitas hidup terutama pada fungsi sekolah dan fungsi emosi. Lama diagnosis >60 bulan, jenis kelamin perempuan, dan jenjang pendidikan menengah merupakan faktor yang berhubungan dengan kualitas hidup anak PGK. ...... Background: Chronic kidney disease CKD is still serious health problem in children with increasing morbidity affect children's quality of life. From Riskesdas 2013, prevalence of patients CKD ge 15 years old in Indonesia is 0,2 . Research in Kuwait shows increasing prevalence children with CKD from 188 1996 to 329 per millions of the age related population in 2003. Aim: To assess the quality of life children with CKD as well as relationship with duration of diagnosis, severity, and related factors demographic. Methods: A cross sectional analytic study. Subjects were recruited from July 2016 May 2017 through consecutive sampling. CKD children aged 2 18 years were involved, patients and their parents were asked to fill out the PedsQL trade generic score scale version 4.0 questionnaire. Result: A total of 112 children were recruited, quality of life was affected from parents's reports 54,5 and children's reports 56,3. The school and emotional have lowest score affected parameter studied. Factor related to quality of life children with CKD were duration of diagnosis 60 months p 0,004 , female p 0,019 , and middle school p 0,003. Conclusion: More than half children with CKD have disturbance quality of life in general from parents's reports 54,5 and children's reports 56,3 . Duration of diagnosis 60 months, female, and middle school were related with quality of life children with CKD.

Abstrak :
Pasien gagal ginjal terminal dengan hemodialisis seringkali melaporkan mengalami pemanjangan waktu pemulihan pascahemodialisis yang berdampak pada rendahnya kualitas hidup pasien. Tujuan penelitian adalah mengidentifikasi faktor-faktor yang berhubungan dengan waktu pemulihan pascahemodialisis. Rancangan yang digunakan adalah deskriptif korelasi dengan pendekatan cross-sectional. Sampel penelitian yaitu 185 pasien hemodialisis di RSUP Sanglah Denpasar yang dipilih dengan teknik consecutive sampling. Hasil penelitian menunjukkan bahwa rata-rata lama waktu pemulihan pascahemodialisis adalah 578,41 402,27 menit. Jadwal hemodialisis p=0,029 , penyakit penyerta p = 0,046 , jumlah komplikasi akut p = 0,0001 dan depresi p = 0,004 ditemukan berhubungan signifikan dengan waktu pemulihan pascahemodialisis. Hasil analisis multivariat menunjukkan bahwa jumlah komplikasi akut selama hemodialisis merupakan faktor yang paling dominan berhubungan dengan waktu pemulihan pascahemodialisis =0,747. Kesimpulannya adalah jenis kelamin, lingkar lengan atas, jadwal hemodialisis, kadar sodium dialisat, intradialytic weight loss, penyakit penyerta dan jumlah komplikasi akut secara bersama-sama memiliki hubungan bermakna dengan waktu pemulihan pascahemodialisis. ...... End stage renal disease undergoing hemodialysis patient often reported a prolonged post hemodialysis recovery time which related to the patient rsquo s low quality of life. This study aimed to identify the factors related to post hemodialysis recovery time. This study used descriptive correlation design with cross sectional method. The samples of the study were 185 hemodialysis patients at Sanglah Central Hospital, Denpasar, recruited by consecutive sampling technique. The result of the study showed that the mean of recovery time was 578.41 402.27 minute. Hemodialysis schedule p 0.029 , comorbid diseases p 0.046, the number of acute complication p 0.0001 and depression p 0.004 were significantly related to post hemodialysis recovery time. The result of multivariate analysis showed that the number of acute complication during hemodialysis was the most dominant factor related to recovery time 0.747. As the conclusion, gender, upper arm circumference, hemodialysis schedule, sodium dialysate concentration, intradialytic weight loss, comorbid diseases, and the number of acute complication altogether shared significant correlation with post hemodialysis recovery time.