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Abstrak :
Latar Belakang: Ekstrak biji anggur (GSE) mengandung 74-78% proantosianidin yang berfungsi sebagai pengikat silang kolagen. Tujuan: menganalisis kemampuan GSE sebagai larutan irigasi saluran akar dalam membersihkan smear layer pada daerah sepertiga apeks. Metode: lima puluh gigi dibagi menjadi lima kelompok. Kelompok 1 meggunakan aquades, kelompok 2 menggunakan GSE 3.25%, kelompok 3 menggunakan GSE 6.5%, kelompok 4 menggunakan GSE 13% dan kelompok 5 menggunakan EDTA 17%. Kemudian dilakukan pemeriksaan tingkat kebersihan sepertiga apeks menggunakan SEM dan diberi skor. Analisis data menggunakan uji kolmogorov-smirnov. Hasil: Skor 0 terbanyak pada GSE 13% (40%), skor 1 terbanyak pada GSE 6.5% (70%) dan skor 2 terbanyak pada aquades (80%). Kesimpulan: Larutan ekstrak biji anggur mempunyai potensi dapat membersihkan smear layer pada daerah sepertiga apeks dinding saluran akar. ......Background: Grape seed extract (GSE) consisting of 74-78% proanthocyanidin, is a cross linking agent. Purpose: investigate the ability of GSE in removing smear layer on apical third of root canal wall. Materials and Method: fifty five extracted incisors were divided into 5 groups. Grup 1 used aquadest, group 2 used 3.25% GSE, group 3 used 6.5% GSE, group 4 used 13% GSE and group 5 used 17% EDTA. The cleanliness of smear layer were evaluated by SEM and scored. The data were analyzed using kolmogorov-smirnov test. Results: Score 0 maximum in group GSE 13% (40%), score 1 maximum in group GSE 6.5% (70%) and score 2 maximum in group aquadest (80%). Conclusion: Grape seed extract solution has a potential to remove smear layer on apical third of root canal wall.

Abstrak :
The aim of this study is to evaluate the effectiveness over application time of different formulations of a novel endodontic irrigant (QMix™ 2in1) composed of a polyaminocarboxylic acid chelating agent, a bisbiguanide antimicrobial agent, a surfactant and deinoized water to remove the root canal smeal layer and expose patent dentinal tubules compared to a standard solution of 17 % EDTA. Eighty human tooth roots from extracted, single-rooted teeth were instrumented (size 40.06) using 0.2 mL of sodium hypochlorite (6.15 %) between each file size with a 3 mL water rinse after final instrumentation. Eight groups of 10 roots were irrigated with 3 mL of different formulations of QMix: QMix A, QMix B, and QMix C, or 17 % or EDTA for 60 and 90 s, respectively, then rinsed with 5 mL of sterile water. The roots were irrigated using a standard irrigation syringe and a 30 ga side-vent needle with an apical-coronal motion to within 1 mm of the working length. The coronal, middle and apical thirds of one canal surface of each root was evaluated at 1000x using scanning electron microscopy. The presence of smeal layer was scored using a 5-point scale. Data were analyzed with the Kruskal-Wallis rank sums test, the Steel-Dwass, all-pairs comparison test, and the Steel method (with control) test. Irrigant type was highly significant (p < 0.007). Combined 60 and 90 s exposure data indicated QMix A (p = 0.014) and QMix C (p = 0.028) were superior to EDTA. While at the 90 s exposure time, smear layer removal by solutions QMix A (p = 0.043), QMix B (p = 0.018), and QMix C (p = 0.011) was superior to EDTA. All irrigants removed smear layer more effectively at the coronal and middle levels compared to the apical level (p < 0.001). Analysis showed all three QMix formulations were superior to EDTA in smear layer removal and exposure of dentinal tubules in the root canal system in single-rooted teeth.