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"Latar Belakang: Perawatan di ruang rawat inap dapat menimbulkan dampak negatif terhadap pasien geriatri dan pelaku rawatnya berupa peningkatan gejala ansietas dan depresi. Ansietas dan depresi yang dialami oleh pelaku rawat dapat mengganggu kualitas perawatan pasien geriatri yang dirawatnya. Tujuan: Mengetahui proporsi pelaku rawat pasien geriatri yang dirawat inap di rumah sakit yang mengalami peningkatan gejala ansietas dan depresi serta mengetahui faktor-faktor apa saja yang mempengaruhi peningkatan gejala ansietas dan depresi tersebut. Metode: Studi dengan desain kohort prospektif untuk meneliti faktor-faktor yang berhubungan dengan peningkatan gejala ansietas dan depresi pada pelaku rawat pasien geriatri yang dirawat inap di Rumah Sakit Cipto Mangunkusumo pada bulan Februari hingga Mei 2018 dengan membandingkan derajat gejala ansietas dan depresi pada hari pertama perawatan dengan hari ketujuh perawatan pasien menggunakan kuesioner Hospital Anxiety and Depression Scale (HADS). Analisis bivariat menggunakan uji Chi Square atau uji Fisher apabila persyaratan uji Chi Square tidak terpenuhi dan analisis multivariat menggunakan regresi logistik.Hasil: Sebanyak 58,1% pelaku rawat pasien geriatri mengalami peningkatan gejala ansietas dan 60,7% pelaku rawat mengalami peningkatan gejala depresi pada saat hari ketujuh perawatan pasien di ruang rawat inap. Berdasarkan analisis multivariat faktor-faktor yang mempengaruhi peningkatan gejala ansietas pelaku rawat pasien geriatri yang dirawat inap di rumah sakit adalah usia pelaku rawat ≥60 tahun (p=0,05; OR 4,167; IK 95% 1,554-11,171), durasi merawat pasien ≥8 jam dalam sehari (p=0,041; OR 4,228; IK 95% 1,060-16,860), lama merawat pasien di ruang rawat inap ≥6 hari (p=0,019; OR 2,500; IK 95% 1,163-5,375) serta merawat pasien geriatri dengan ketergantungan berat-total (p<0,001; OR 5,568; IK 95% 2,323-13,345). Faktor-faktor yang mempengaruhi peningkatan gejala depresi pelaku rawat pasien geriatri yang dirawat inap di rumah sakit di antaranya usia pelaku rawat ≥60 tahun (p=0,01; OR 9,333; IK 95% 2,638-33,018), durasi merawat pasien ≥8 jam dalam sehari (p=0,008; OR 8,392; IK 95% 1,723-40,880), lama merawat pasien di ruang rawat inap ≥6 hari (p<0,001; OR 4,184; IK 95% 1,982-9,256) serta merawat pasien geriatri dengan ketergantungan berat-total (p=0,007; OR 3,132; IK 95% 1,372-7,151). Kesimpulan: Usia pelaku rawat ≥60 tahun, durasi merawat pasien ≥8 jam dalam sehari, lama merawat pasien di ruang rawat inap ≥6 hari serta merawat pasien geriatri dengan ketergantungan berat-total mempengaruhi peningkatan gejala ansietas dan depresi pelaku rawat pasien geriatri yang dirawat inap di rumah sakit.

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Background: Hospitalization can cause negative impact on geriatric patients and also their caregivers such as increased symptoms of anxiety and depression. Anxiety and depression experienced by the caregivers can interfere the quality of care for the geriatric patients. Objectives: To determine the proportion of geriatric patients caregivers with increased anxiety and depression symptoms during hospitalization using Hospital and Anxiety Depression Scale (HADS) questionnaires and its associated factors. Methods: A prospective cohort study was conducted to determine the associated factors of increased anxiety and depression symptoms in caregivers of hospitalized geriatric patients at Cipto Mangunkusumo Hospital from February to May 2018 by comparing anxiety and depression symptoms level on the first day of hospitalization with the seventh day using HADS questionnaires. Bivariate analysis was done using Chi Square test or Fisher test when the requirement for Chi Square test was not fullfilled. Multivariate analysis was also done using logistic regression.Result: As many as 58.1% caregivers of hospitalized geriatric patients had an increased anxiety symptoms and 60.7% caregivers experienced increased depression symptoms on seventh day of hospitalization. Multivariate analysis showed that caregivers aged 60 years old or above (p=0.005; OR 4.167; 95% CI 1.554-11.171), duration of caregiving equal to or more than 8 hours in a day (p=0.041; OR 4.228; 95% CI 1.060-16.860), duration of caregiving equal to or more than 6 days in a week (p=0.019; OR 2.500; 95% CI 1.163-5.375) and caregiving for patient with severe to total dependency (p<0.001; OR 5.568; 95% CI 2.323-13.345) are significantly increased the anxiety symptoms. Factors that are significantly increased the depression symptoms including caregivers aged 60 years old or above (p=0.01; OR 9.333; 95% CI 2.638-33.018), duration of caregiving equal to or more than 8 hours in a day (p=0.008; OR 8.392; 95% CI 1.723-40.880), duration of caregiving equal to or more than 6 days in a week (p<0.001; OR 4.184; 95% CI 1.982-9.256) and caregiving for patient with severe to total dependency (p=0.007; OR 3.132; 95% CI 1.372-7.151). Conclusion: Caregiver aged 60 years old or above, duration of caregiving equal to or more than 8 hours in a day, duration of caregiving equal to or more than 6 days in a week, and caregiving for patient with severe to total dependency are significantly increased anxiety and depression symptoms in caregivers of hospitalized geriatric patients."

"Latar Belakang: Ansietas dan depresi merupakan gangguan psikosomatis yang paling banyak ditemukan. Pada pasien Lupus Eritematosus, ansietas merupakan gangguan mood paling banyak ditemukan dibandingkan depresi. Selain bagian dari manifestasi NPSLE, ansietas dan depresi dapat memicu terjadinya inflamasi yang akan memengaruhi aktivitas lupus. Hospital Anxiety dan Depresi Scale (HADS) merupakan salah satu skala pengukuran ansietas dan depresi yang berbentuk kuesioner yang mudah digunakan dansudah tervalidasi. Mexican Systemic Lupus Erythemathosus Sistemic Disease Activity (Mex SLEDAI) merupakan sistem skoring untuk pasien LES yang mudah dan lebih murah serta memiliki reliabilitas dan validitas yang baik. Saat ini belum ada yang meneliti perihal hubungan ansietas dan depresi yang menggunakan HADS dengan kadar C3 danC4 pada pasien LES.Tujuan: Mengetahui korelasi antara ansietas dan depresi dengan kedua kadar C3 dan C4 pada pasien LES di RSCM.Metode: Penelitian ini menggunakan desain potong lintang, dilakukan analisis data primer pasien LES usia 18-60 tahun. Dilakukan wawancara dan pemeriksaan fisik serta pengisian kuesioner HADS diikuti dengan pengambilan sampel darah untuk menilai kadar C3 dan C4. Korelasi antara skor HADS ansietas dan depresi dengan kadar C3 dan C4, dan serta Mex-SLEDAI didapat dengan uji korelasi Spearman menggunakan SPSS.Hasil: Dari 120 sampel dengan median usia 31 tahun (24-37), penggunaan steroid dengan median 16 mg/minggu (0-28), dan aktivitas lupus dengan median 6 (0-11). Didapatkan korelasi antara ansietas dengan kadar C3 dan C4 yang signifikan dengan nilai r = -0,189 dan r = -0,206. Tidak didapatkan korelasi depresi dengan kadar C3 dan C4 ataupun korelasi ansietas dan depresi dengan aktivitas lupus.Kesimpulan: Terdapat korelasi negatif antara HADS ansietas dengan kadar C3 ataupun C4.......Background: Anxiety and depression are the most common psychosomatic disorders. Both of them have the highest prevalence of chronic diseases. In Lupus Erythematosus patients, anxiety is more common compared to depression. They have been widely penelitianed and found to have a clinical relationship. Not only they are one of the manifestations of NPSLE, they can also trigger inflammation that will affect lupus activity. On the other hand, many patients with anxiety and depression are undiagnosed and treated inappropriately. There is a screening tool that can measure both disorders quantitatively, namely the Hospital Anxiety and Depression Scale (HADS). Mexican Systemic Lupus Erythematosus Systemic Disease Activity (Mex-SLEDAI) can also be used to measure lupus activity. The advantage of this scoring is that it can be tested without measuring complement or anti-dsDNA levels, which is not necessarily available in every hospital. One of the factors that affects the activity of lupus is complement activity. Currently, no one has investigated the relationship between anxiety anddepression using HADS with levels of C3 and C4 in SLE patients.Objective: To determine the correlation between anxiety and depression with levels of C3 and C4 in SLE patients in RSCM.Methods: This study used a cross-sectional design, analyzed the primary data of SLE patients aged 18-60 years. Interviews and physical examinations were carried out as well as filling out the HADS questionnaire followed by taking blood samples to assess C3 and C4 levels. The correlation between HADS scores of anxiety and depression with levelsof C3 and C4, and Mex-SLEDAI was obtained using the Spearman correlation test using SPSS.Results: 120 samples with a median age of 31 years (24-37), with the use of steroid doses with a median of 16 mg/week (0-28) and lupus activity with a median of 6 (0-11), there was a correlation between anxiety HADS and C3 levels and C4 which is significant with a value of r = -0.189 and r = -0.206. However, for HADS Depression with levels of C3 or C4 no correlation was found. In addition, in this study, there was no correlation between HADS Anxiety and Depression with Lupus Mex Sledai activityConclusion: There was a negative correlation between HADS Anxiety and levels of C3 or C4."