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Hasil Pencarian

Ditemukan 2 dokumen yang sesuai dengan query
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Andri Sanityoso Sulaiman, author
Hubungan SNP IL-28B Pejamu dengan Respons Virologis Menetap serta Kaitannya dengan Ekspresi Interferon-3 dan Reseptor Interferon-λ3 di Jaringan Hati pada Pasien Hepatitis C Kronik dengan Pengobatan Pegylated Interferon Α2 dan Ribavirin = Association between SNP IL-28B and Sustained Virological Response and Its Relation with Expression of Interferon Lambda-3 and Interferon Lambda-3 Receptor in Liver Tissues of Chronic Hepatitis C Patients Treated with Pegylated Interferon α2 and Ribavirin
[ABSTRAK
Latar Belakang. SNP IL-28B mempunyai peran penting dalam pencapaian SVR pada pengobatan Hepatitis C kronik antarras manusia dan berpotensi untuk memprediksi keberhasilan terapi Peg-IFN/RBV maupun penyembuhan spontan Hepatitis C akut. Hingga saat ini, mekanisme molekular yang mendasari kaitan SNP IL-28B dengan respons terapi masih belum jelas meskipun diperkirakan terkait dengan...
2015
D-Pdf
UI - Disertasi Membership  Universitas Indonesia Library
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The role of hepatitis C virus NS5A region mutation and SNP IL-28B of host to support successful pegylated interferon and ribavirin treatment in patients with HCV-HIV coinfection: a prospective cohort study
Background: HIV infection in HCV-infected patients accelerates disease progression and reduces the success rate of Peg-IFN/RBV treatment. HCV mutation in NS5A-ISDR/PKR-BD region improved the outcome in HCV monoinfection treated with Peg-IFN/RBV. SNP-IL28B polymorphism is predicted to have an effect on HCV quasispecies evolution. However, the role of NS5A mutation and...
Depok: Universitas Indonesia, 2019
610 UI-IJIM 51:2 (2019)
Artikel Jurnal  Universitas Indonesia Library