Hasil Pencarian  ::  Simpan CSV :: Kembali

"Hormones and women's lives -- Monthly challenges -- When hormones hurt -- Hormones make sex possible or nearly impossible -- The most visible part of your body may be the most vulnerable: what hormones can do to skin and hair-Menopause: straight talk on the tough questions-Hormones and the soul"

"Lippincott Illustrated Reviews: Pharmacology, Sixth Edition, is the updated, enhanced version of the student-favorite resource for essentials of medical pharmacology. The first-and-best resource, the Lippincott Illustrated Reviews series features clear, effective writing and hundreds of illustrations for ideal rapid review and the assimilation of complex information. Clear, sequential images present mechanisms of action and focus on showing rather than telling students how drugs work. New edition features: All NEW chapters on Drugs of Abuse, Drugs for Obesity, Antihistamines, Drugs for Urologic Disorders, Drugs for Hematopoietic Disorders, Drugs for Dermatological Disorders, and Drugs for Bone Disorders; Over 380 study questions; Nearly 600 annotated, full-color illustrations visually explain complex processes; Outline format ideal for concise review and foundational learning."

"Latar Belakang: Prevalensi Diabetes Melitus (DM) tipe 2 cenderung meningkat di seluruh dunia dan keteraturan pengobatan masih menjadi masalah hingga saat ini. Penelitian terdahulu menemukan bahwa terdapat hubungan antara temperamen dengan kontrol glukosa namun belum banyak penelitian yang membahas hal ini. Penelitian ini bertujuan mengetahui hubungan antara temperamen dengan terkontrol atau tidak terkontrolnya DM tipe 2.Metode: Penelitian ini adalah penelitian analitik potong lintang. Pengambilan sampel dilakukan dengan consecutive sampling pada 110 penyandang DM tipe 2 di Poliklinik Metabolik Endokrin RSCM selama bulan Agustus-Desember 2015. Responden dikelompokkan menjadi penyandang DM terkontrol atau DM tidak terkontrol berdasarkan hasil laboratorium HbA1c terakhir. Responden mengisi kuesioner Modified-Temperament and Character Inventory versi bahasa Indonesia.Hasil: Hasil penelitian ini menunjukkan bahwa skor temperamen harm avoidance, novelty seeking, dan reward dependence tidak berhubungan bermakna dengan terkontrol atau tidak terkontrolnya DM tipe 2.Simpulan: Tidak ada hubungan bermakna antara temperamen dengan pengendalian kadar HbA1c pada penyandang DM tipe 2.

---

Background: Prevalence on type 2 Diabetes Mellitus (DM) tend to increase across the world and regulating treatment still being one of the matters to be discussed until recently. Previous research had found that there are correlations between temperament with glucose control but with limited study on that area. This research aim to qualify the relationship between temperament to controllable or uncontrollable type 2 DM.

Method: This research is a cross sectional sampling method. Sampling conducted with consecutive sampling on 110 respondents with type 2 DM in RSCM Metabolism Endocrine Polyclinic, sampling was done between August to December 2015. Respondents are grouped to two different groups which is controllable DM and uncontrollable DM based on last HbA1c laboratory results. Respondents were requested to fill up Modified-Temperament and Character Inventory questionnaire in Bahasa Indonesia.

Results: Result on this research indicates that temperament score in harm avoidance, novelty seeking, and reward dependence are unrelated with whether Type 2 DM being controllable or uncontrollable.

Conclusion: Absent of significant relation between temperament and HbA1c level control in type 2 DM patients."

"diwujudkan melalui proses pendidikan berkelanjutan setelah magister keperawatan. Program praktik residensi ners spesialis keperawatan medikal bedah peminatan endokrin, bertujuan agar para residen memiliki tingkat kompetensi profesional, berpikir kritis dan reflektif serta komunikasi interpersonal yang lebih tinggi ketika dihadapkan pada situasi klinis yang kompleks. Praktik dilakukan di ruang gawat darurat, ruang intensif, rawat inap, dan rawat jalan RSUPN Dr Cipto Mangunkusumo Jakarta dengan mengaplikasikan teori Model Adaptasi Roy pada 30 kasus resume dan 1 kasus utama pada pasien diabetes melitus tipe 2 dengan komplikasi peripheral arterial disease dan ulkus kaki diabetik. Penerapan evidence based nursing Short Form Berg balance Scale telah terbukti sebagai alat skrining yang mudah, murah, hemat waktu dan memiliki reliabilitas Intraclass Correlation Coefisien yang baik untuk pengkaji keseimbangan dan resiko jatuh pada pasien DM yang sudah lanjut usia. Penerapan inovasi New Simulation Tools terbukti efektif mengurangi rasa takut pasien terhadap jarum suntik dan meningkatkan keterampilan menyuntik pada pasien yang baru pertama kali menerima terapi insulin.

---

The nursing profession always develops following the latest science. This is realized through a process of continuing education after the master of nursing. The residency practice program for medical surgical nursing specialists specializing in endocrine, aims to make residents have a higher level of professional competence, critical and reflective thinking and interpersonal communication when faced with complex clinical conditions. The practice was carried out in the emergency room, intensive care unit, inpatient and outpatient care at RSUPN Dr Cipto Mangunkusumo Jakarta by applying Roy's Adaptation Model theory to 30 resume cases and 1 main case in patients with type 2 diabetes melitus with complications of peripheral arterial disease and diabetic foot ulcers. . The application of evidence-based nursing Short Form Berg balance Scale has been proven as a screening tool that is easy, inexpensive, time-saving and has good Intraclass Correlation Coefficient reliability for assessing balance and risk of falling in elderly DM patients. The application of the innovative New Simulation Tools has been proven to be effective in reducing patients' fear of needles and improving injecting skills in patients who are receiving insulin therapy for the first time."

"Penyakit endokrin merupakan penyebab kematian dengan angka yang cukup tinggi baik secara nasional maupun global. Hal ini menjadi tantangan bagi seluruh tenaga kesehatan khususnya bagi perawat spesialis medikal bedah peminatan endokrin dalam ikut membantu menurunkan tingkat komplikasi yang terjadi. Praktik ilmu keperawatan yang berkualitas berdasarkan evidence base nursing terbaru menjadi landasan dalam melaksanakan peran sebagai pemberi asuhan, peneliti, pendidik dan inovator. Praktik residensi perawat spesialis peminatan endokrin berlangsung dalam dua semester telah memberikan pengalaman dan kesempatan untuk menerapkan teori keperawatan secara menyeluruh dalam mengelola asuhan kepada pasien. Penerapan model teori adaptasi Roy dilakukan oleh residen terhadap 30 kasus resume dan satu kasus kelolaan utama yaitu pada pasien Diabetes Melitus type 2 dengan riwayat KAD, akut on CKD, hipertensi, dyslipidemia dan pankreatitis akut. Peran peneliti dilakukan dengan menerapkan evidence base nursing yaitu melalui inlows sixty second sebagai alat screening risiko terjadinya luka kaki pada pasien Diabetes Melitus. Inovasi pelayanan yang dilakukan residen adalah membuat alat simulation tool yaitu alat edukasi untuk pasien Diabetes Melitus yang menerima terapi insulin pertama kali. Protokol ini mampu memberikan panduan secara sistematis, mudah dipahami, serta mudah dilaksanakan oleh perawat kepada pasien sehingga diharapkan pasien dengan terapi insulin tidak merasa ketakutan saat mendapatkan insulin pertama kali.

---

Endocrine disease is a cause of death with a fairly high number both nationally and globally. This is a challenge for all health workers, especially for medical surgical specialist nurses specializing in endocrine in helping to reduce the rate of complications that occur. Quality nursing science practice based on the latest nursing evidence base is the cornerstone in carrying out the role as a caregiver, researcher, educator and innovator. The endocrine specialist nurse residency practice which takes place over two semesters has provided experience and opportunity to apply nursing theory as a whole in managing care for patients. Residents applied Roy's adaptation theory model to 30 resume cases and one main managed case, namely type 2 Diabetes Melitus patients with a history of DKA, acute CKD, hypertension, dyslipidemia and acute pancreatitis. The role of the researcher is carried out by applying evidence-based nursing, namely through sixty second inlows as a screening tool for the risk of foot injuries in patients with Diabetes Melitus. The resident's service innovation is to make a simulation tool, which is an educational tool for Diabetes Melitus patients who receive insulin therapy for the first time. This protocol is able to provide guidance in a systematic, easy to understand, and easily implemented by nurses to patients so that patients on insulin therapy are expected not to feel afraid when they get insulin for the first time."

"Basic Medical Endocrinology, Third Edition provides up-to-date coverage of rapidly unfolding advances in the understanding of hormones involved in regulating most aspects of bodily functions. The discussion focuses on molecular and cellular aspects of hormone production and action firmly rooted in the context of integrative physiology. Topics are approached from the perspective of a physiologist with four decades of teaching experience. This book is richly illustrated with both descriptive schematic diagrams and laboratory findings obtained in clinical studies. Each of the thirteen in-depth chapters starts with an 'Overview' of the topic and ends with a 'Suggested Reading' list."

"Praktik residensi keperawatan medikal bedah peminatan keperawatan endokrin merupakan kelanjutan dari pendidikan magister keperawatan yang dilaksanakan dalam rangka memberikan kesempatan dan pengalaman kepada residen perawat untuk menerapkan ilmu dan teknologi keperawatan khususnya memberi asuhan keperawatan lanjut dan kompleks dalam menyelesaikan permasalahan keperawatan endokrin pada fasilitas pelayanan kesehatan. Praktik klinik dilaksanakan di setting gawat darurat, perawatan intensif, rawat inap, dan rawat jalan di RSUPN Dr Cipto Mangunkusumo Jakarta. Penerapan teori Model Adaptasi Roy dilakukan oleh residen pada 30 kasus resume dan 1 kasus utama yaitu pada pasien SIDA on ARV, Diabetes mellitus tipe 2, Selulitis regio colli, Hepatitis C, Sirosis hepatis. Asuhan keperawatan berbasis bukti diterapkan berupa latihan Passive Stretching untuk menurunkan gula darah pada pasien yang tidak mampu melakukan latihan fisik mandiri. Inovasi pelayanan keperawatan dilakukan dengan menyusun media edukasi simulasi suntik insulin yang terdiri dari alat New Simulation Tools (alat peraga suntik insulin) video dan buku panduan edukasi suntik insulin (buklet) yang digunakan sebagai panduan dan media edukasi bagi perawat dalam memberikan edukasi suntik insulin, mengurangi rasa takut pasien terhadap penyuntikan, memberikan lebih banyak latihan, dan meningkatkan keterampilan penyuntikan insulin pasien.

---

The medical surgical nursing residency program specializing in endocrine nursing is a continuation of nursing master education which is carried out in order to provide opportunities and experience to nurse residents to apply nursing science and technology, especially providing advanced and complex nursing care in solving endocrine nursing problems in health care facilities. Clinical practice is carried out in emergency, intensive care, inpatient, and outpatient settings at Dr. Cipto Mangunkusumo Hospital Jakarta. The application of the Roy Adaptation Model theory was carried out by residents in 30 resume cases and 1 main case, namely in patients with SIDA on ARV, Diabetes mellitus type 2, Cellulitis regio colli, Hepatitis C, Cirrhosis hepatis. Evidence-based nursing care is applied in the form of Passive Stretching exercises to reduce blood sugar in patients who are unable to do independent physical exercise. Nursing service innovation is carried out by compiling educational media consisting of insulin injection simulation tools consisting of New Simulation Tools (insulin injection tool) videos and insulin injection education guidebooks (booklets) which are used as guidelines and educational media for nurses in providing insulin injection education, reducing patient fear of injections, providing more practice, and improving patient insulin injection skills."

"Menikah dan memiliki keturunan merupakan sebuah fase penting dalam siklus kehidupan. Apabila kehamilan tak kunjung terjadi setelah dua belas bulan berhubungan teratur tanpa pengaman, maka disebut sebagai infertilitas. Fertilisasi in vitro (FIV) dilakukan saat metode lain telah mengalami kegagalan, namun tahapan yang dilalui memberikan stres bagi yang menjalaninya. Melihat kompleksitas permasalahan, perlu untuk dikembangkan model pendampingan, berupa Terapi Kognitif Perilaku (TKP). Penelitian ini bertujuan untuk mengetahui efektivitas TKP dalam memperbaiki faktor psiko-neuro-endokrin.Penelitian terdiri dari dua tahap yaitu uji face validity dan studi eksperimental berupa uji klinis tersamar ganda. Penelitian dilakukan di Klinik Infertilitas Yasmin RSCM dan Klinik Dr Sander B Daya Medika. Waktu penelitian adalah bulan Mei 2016 – Maret 2023. Pengumpulan data menggunakan kuesioner dan penilaian selama prosedur FIV, meliputi kecemasan, depresi, serta kadar hormonal berupa kortisol, norepinefrin, triiodotironin bebas (fT3), estradiol, dan progesteron. Interaksi antara kelompok intervensi dan waktu pengukuran terhadap variabel dianalisis dengan menggunakan mixed-model repeated measure ANOVA dan analisis post-hoc menggunakan uji t tidak berpasangan pada setiap pengukuran.Analisis akhir melibatkan 75 subjek, terdiri dari 38 subjek kelompok kontrol dan 37 subjek kelompok TKP. Distorsi kognitif yang paling sering dialami subjek penelitian adalah fortune telling (34,2%), personalization (22,8%), dan should statement (14,3%). Terdapat penurunan skor kecemasan di sesi 8 TKP (p < 0,001) dan penurunan skor depresi di sesi 6 dan 8 TKP (p = 0,027 dan p = 0,007). Penurunan skor kecemasan sejalan dengan penurunan kadar norepinefrin (p = 0,002), sementara penurunan skor depresi bersesuaian dengan penurunan kadar kortisol (p < 0,001) dan perbaikan kadar estradiol (p = 0,024). Kadar fT3 dan progesteron tidak mengalami perbaikan hingga akhir sesi TKP. Mixed-model repeated measure ANOVA menguatkan hasil dengan adanya tren penurunan kecemasan, depresi, norepinefrin, dan kortisol pada kelompok TKP, dengan ukuran efek kecil hingga sedang.Dari hasil penelitian disimpulkan bahwa TKP terbukti efektif dalam memperbaiki faktor psiko-neuro-endokrin pada perempuan yang mengikuti FIV. Penting untuk dilakukan advokasi hasil penelitian kepada rumah sakit dengan layanan FIV dan mengintegrasikan panduan TKP pada FIV ke dalam prosedur standar dan panduan pelayanan klinis rumah sakit. Penting untuk melakukan penelitian lanjutan pada populasi dengan karakteristik lebih beragam dan mengembangkan bentuk pendampingan bagi pasangan agar dapat memberikan dukungan yang adekuat dan mengoptimalkan luaran FIV.

---

Marriage and parenthood are significant life stages. When a couple has regular, unprotected intercourse for 12 months without pregnancy, they are considered infertile. In vitro fertilization (IVF) is pursued when other methods fail, though it can cause significant stress for women. This study aims to assess the effectiveness of Cognitive Behavioral Therapy (CBT) in improving psycho-neuro-endocrine factors in women undergoing IVF.

The research comprises two phases: the assessment of face validity and an experimental study designed as a double-blind clinical trial, conducted at the Yasmin Infertility Clinic RSCM and Dr. Sander B Daya Medika Clinic. The research spanned from May 2016 – March 2023. Data were collected through questionnaires and evaluations during the IVF process, focusing on anxiety, depression, and hormonal levels, including cortisol, norepinephrine, free triiodothyronine (fT3), estradiol, and progesterone. The interaction between the intervention group and the timing of measurements for each variable was analyzed using a mixed-model repeated measures ANOVA and post hoc analysis with an unpaired t-test at each measurement interval.

The final analysis comprised 75 participants, 38 assigned to the control and 37 to the cognitive behavioral therapy (CBT) group. The predominant cognitive distortions identified included fortune telling (34.2%), personalization (22.8%), and should statements (14.3%). Notably, there was a significant reduction in anxiety scores observed during session 8 of CBT (p < 0.001), alongside a marked decrease in depression scores during sessions 6 and 8 (p = 0.027 and p = 0.007, respectively). The decline in anxiety scores was significantly correlated with a reduction in norepinephrine levels (p = 0.002), while the decrease in depression scores was linked to a significant drop in cortisol levels (p < 0.001) and an enhancement in estradiol levels (p = 0.024). However, no improvements were noted in the levels of fT3 and progesterone. The mixed-model repeated measures ANOVA corroborated these findings, indicating a significant trend in the reduction of anxiety, depression, norepinephrine, and cortisol within the CBT group, with effect sizes ranging from small to medium.

It can be inferred that CBT is effective in enhancing psycho-neuro-endocrine factors among women undergoing IVF. Consequently, it is crucial to promote these research outcomes within IVF service hospitals and incorporate CBT protocols into standard practices and clinical guidelines. Additional research should be pursued involving more diverse populations and the formulation of support models for couples, aimed at delivering adequate assistance to women undergoing IVF and optimizing the outcomes of the procedure."

"Menikah dan memiliki keturunan merupakan sebuah fase penting dalam siklus kehidupan. Apabila kehamilan tak kunjung terjadi setelah dua belas bulan berhubungan teratur tanpa pengaman, maka disebut sebagai infertilitas. Fertilisasi in vitro (FIV) dilakukan saat metode lain telah mengalami kegagalan, namun tahapan yang dilalui memberikan stres bagi yang menjalaninya. Melihat kompleksitas permasalahan, perlu untuk dikembangkan model pendampingan, berupa Terapi Kognitif Perilaku (TKP). Penelitian ini bertujuan untuk mengetahui efektivitas TKP dalam memperbaiki faktor psiko-neuro-endokrin.Penelitian terdiri dari dua tahap yaitu uji face validity dan studi eksperimental berupa uji klinis tersamar ganda. Penelitian dilakukan di Klinik Infertilitas Yasmin RSCM dan Klinik Dr Sander B Daya Medika. Waktu penelitian adalah bulan Mei 2016 – Maret 2023. Pengumpulan data menggunakan kuesioner dan penilaian selama prosedur FIV, meliputi kecemasan, depresi, serta kadar hormonal berupa kortisol, norepinefrin, triiodotironin bebas (fT3), estradiol, dan progesteron. Interaksi antara kelompok intervensi dan waktu pengukuran terhadap variabel dianalisis dengan menggunakan mixed-model repeated measure ANOVA dan analisis post-hoc menggunakan uji t tidak berpasangan pada setiap pengukuran.Analisis akhir melibatkan 75 subjek, terdiri dari 38 subjek kelompok kontrol dan 37 subjek kelompok TKP. Distorsi kognitif yang paling sering dialami subjek penelitian adalah fortune telling (34,2%), personalization (22,8%), dan should statement (14,3%). Terdapat penurunan skor kecemasan di sesi 8 TKP (p < 0,001) dan penurunan skor depresi di sesi 6 dan 8 TKP (p = 0,027 dan p = 0,007). Penurunan skor kecemasan sejalan dengan penurunan kadar norepinefrin (p = 0,002), sementara penurunan skor depresi bersesuaian dengan penurunan kadar kortisol (p < 0,001) dan perbaikan kadar estradiol (p = 0,024). Kadar fT3 dan progesteron tidak mengalami perbaikan hingga akhir sesi TKP. Mixed-model repeated measure ANOVA menguatkan hasil dengan adanya tren penurunan kecemasan, depresi, norepinefrin, dan kortisol pada kelompok TKP, dengan ukuran efek kecil hingga sedang.Dari hasil penelitian disimpulkan bahwa TKP terbukti efektif dalam memperbaiki faktor psiko-neuro-endokrin pada perempuan yang mengikuti FIV. Penting untuk dilakukan advokasi hasil penelitian kepada rumah sakit dengan layanan FIV dan mengintegrasikan panduan TKP pada FIV ke dalam prosedur standar dan panduan pelayanan klinis rumah sakit. Penting untuk melakukan penelitian lanjutan pada populasi dengan karakteristik lebih beragam dan mengembangkan bentuk pendampingan bagi pasangan agar dapat memberikan dukungan yang adekuat dan mengoptimalkan luaran FIV.

---

Marriage and parenthood are significant life stages. When a couple has regular, unprotected intercourse for 12 months without pregnancy, they are considered infertile. In vitro fertilization (IVF) is pursued when other methods fail, though it can cause significant stress for women. This study aims to assess the effectiveness of Cognitive Behavioral Therapy (CBT) in improving psycho-neuro-endocrine factors in women undergoing IVF.

The research comprises two phases: the assessment of face validity and an experimental study designed as a double-blind clinical trial, conducted at the Yasmin Infertility Clinic RSCM and Dr. Sander B Daya Medika Clinic. The research spanned from May 2016 – March 2023. Data were collected through questionnaires and evaluations during the IVF process, focusing on anxiety, depression, and hormonal levels, including cortisol, norepinephrine, free triiodothyronine (fT3), estradiol, and progesterone. The interaction between the intervention group and the timing of measurements for each variable was analyzed using a mixed-model repeated measures ANOVA and post hoc analysis with an unpaired t-test at each measurement interval.

The final analysis comprised 75 participants, 38 assigned to the control and 37 to the cognitive behavioral therapy (CBT) group. The predominant cognitive distortions identified included fortune telling (34.2%), personalization (22.8%), and should statements (14.3%). Notably, there was a significant reduction in anxiety scores observed during session 8 of CBT (p < 0.001), alongside a marked decrease in depression scores during sessions 6 and 8 (p = 0.027 and p = 0.007, respectively). The decline in anxiety scores was significantly correlated with a reduction in norepinephrine levels (p = 0.002), while the decrease in depression scores was linked to a significant drop in cortisol levels (p < 0.001) and an enhancement in estradiol levels (p = 0.024). However, no improvements were noted in the levels of fT3 and progesterone. The mixed-model repeated measures ANOVA corroborated these findings, indicating a significant trend in the reduction of anxiety, depression, norepinephrine, and cortisol within the CBT group, with effect sizes ranging from small to medium.

It can be inferred that CBT is effective in enhancing psycho-neuro-endocrine factors among women undergoing IVF. Consequently, it is crucial to promote these research outcomes within IVF service hospitals and incorporate CBT protocols into standard practices and clinical guidelines. Additional research should be pursued involving more diverse populations and the formulation of support models for couples, aimed at delivering adequate assistance to women undergoing IVF and optimizing the outcomes of the procedure."