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Tarnimatul Ummah
Asuhan Keperawatan Psikososial: Ketidakberdayaan pada Klien dengan Gagal Jantung di Ruang Antasena RS dr H Marzoeki Mahdi Bogor = Psychosocial Nursing Care Plan: Powerlessness in Heart Failure Patient hospitalized in Antasena Room RS dr H Marzoeki Mahdi Bogor
"ABSTRAK
Ketidakberdayaan dapat terjadi pada individu yang menderita gagal jantung akibat tanda gejala yang dirasakan, dan menjadi permasalahan psikososial yang berpengaruh pada fungsi fisik individu dengan gagal jantung. Karya ilmiah akhir ners ini memaparkan asuhan keperawatan psikososial ketidakberdayaan selama empat hari pada pasien dengan gagal jantung di Ruang Antasena RS dr H Marzoeki Mahdi Bogor. Implementasi keperawatan yang dilakukan berupa menggali perasaan, melatih berpikir positif, mengidentifikasi aspek positif diri yang masih dapat dilakukan sesuai kemampuan, dan memilih target realistis yang dapat dicapai. Karya ilmiah ini menunjukkan bahwa intervensi keperawatan ketidakberdayaan yang optimal melibatkan keluarga menunjukkan penerimaan terhadap penyakit pada pasien dan menumbuhkan rasa berdaya, sehingga klien mampu menumbuhkan harapan diri dan tujuan realistis dalam hidupnya. Oleh karena itu, hubungan timbal balik antara fungsi fisik dan psikososial pasien gagal jantung perlu menjadi perhatian yang menjadi dasar pemberian asuhan keperawatan yang holistik
ABSTRACT
Powerlessness may occur in heart failure patient due to its symptoms, and may become psychosocial problem affect the physical function. This work describes psychosocial nursing care plan of powerlessness given to heart failure patient in Antasena Room Dr H Marzoeki Mahdi Hospital Bogor for four days. The nursing implementation are include letting the patient to express her feelings, building positive thinking, identifying positive aspects of herself according to her physical ability, and choosing the realistic goals. This scientific work demonstrates that optimal nursing intervention of powerlessness involving the family show acceptance of the disease in the patient and foster a sense of empowerment, so that the client is able to foster self expectations and realistic goals in his life. Therefore, the interrelationships between physical and psychosocial aspect of the heart failure patient should be noted as the basis of holistic care nursing"
Depok: Fakultas Farmasi Universitas Indonesia, 2017
PR-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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The Heart, arteries, and veins/editors, Robert C. Schlant, R. Wayne Alexander; associate editors, Robert A. O'Rourke, Roberts, Edmond H. Sonnenblick
New York: McGraw-Hill, 1994
616.1 HEA
Buku Teks  Universitas Indonesia Library
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Stevanus Agus Rahardjo
Analisis praktik residensi keperawatan medikal bedah pada pasien dengan gangguan sistem kardiovaskuler dengan pendekatan teori Imogene King Di Rumah Sakit Jantung Dan Pembuluh Darah Harapan Kita Jakarta = Analysis of Medical Practice Nursing Residency Specialist Residency Reports with the Application of the Imogene King Theory in National Cardiovascular Center Harapan Kita Jakarta
"Analisis laporan praktek residensi merupakan analisis yang dilakukan selama penulis menjalankan praktek residensi 1, 2 dan 3 di Rumah Sakit Jantung Pusat Nasional Harapan Kita Jakarta. Laporan berisi asuhan keperawatan kasus kardiovaskuler yang terdiri dari 1 kasus kelolaan utama, dan 30 kasus resume, dengan penerapan teori keperawatan model Imogene King, pembuatan Evidence Best Nursing serta pembuatan inovasi keperawatan. Tujuan analisis ini adalah untuk memberikan gambaran peran perawat dalam penatalaksanaan keperawatan selama praktik residensi spesialis keperawatan medikal bedah dengan penerapan teori Imogene King pada kasus kardiovaskuler di RS Jantung Harapan Kita Jakarta dan merupakan salah satu bentuk pertanggung jawaban terhadap pengelolaan kasus pasien Acut Decompensated Heart Failure /ADHF pada pasien Coronary Artery Disease
/CAD. Teori Imogene King adalah teori pencapaian tujuan yang dapat digunakan pada pasien dengan kasus kardiovaskuler mulai tahap pengkajian, perencanaan, implementasi sampai dengan evaluasi dalam usaha mencapai kesembuhan dan mencegah kekambuhan yang melibatkan peran pasien dan keluarga. Pelaksanaan EBN (Evidence Base Nursing) dilakukan di unit
intermediate bedah yaitu melatih pasien dengan Inspiratory Muscle Training / IMT dengan penggunaan spirometri untuk melatih otot-otot diafragma dan nafas dalam untuk memperbaiki ekspansi paru dan menaikkan kapasitas paru.
Hasil analisa menunjukan terdapat peningkatan kapasitas paru dan penurunan angka kejadian ateletaksis pada pasien intervensi. Kegiatan inovasi dilakukan di unit kamar bedah yaitu membuat prosedur handover antar personal dalam
intra-operatif dalam rangka patient safety. Hasil menunjukan perawat dapat menerima perubahan atau prosedur baru yang bertujuan mencegah kesalahan dalam melakukan hand over intra operatif antar personal.
Analysis of residency practice reports is an analysis conducted during the authors activity residency practices 1, 2 and 3 at National Cardiovascular Center Harapan Kita Jakarta. The report contains nursing care of cardiovascular cases consisting of one main management case, and 30 cases
of resumes, with the application of Imogene King's model nursing theory, make Evidence Best and Inovation of Nursing. The purpose of this analysis is to provide an overview of the role of nurses in nursing management during the residency practice of surgical medical nursing specialists with the application of the Imogene King theory in cardiovascular cases at National Cardiovascular Center Harapan Kita Jakarta. This is the one of responsibility for managing cases of Acut Decompensated Heart Failure /
ADHF in Coronary Artery Disease / CAD. Imogene King's Theory is a theory of goal attainment that for patients with cardiovascular cases from assessment, planning, implementation to evaluation in an effort to achieve
recovery and prevent recurrence admitted which involving the role of the patient and families. EBN (Evidence Base Nursing) is carried out in the intermediate surgical unit, which is to train patients with Inspiratory Muscle
Training / IMT by using spirometry to train diaphragm muscles and deep breathing to improve lung expansion and increase lung capacity. The analysis showed that increase the lung capacity and decrease in the incidence of ateletaxis. Innovation activities made inter-personal handover intra-operative procedures in in the operating room. The result showed nurses accept new procedures to prevent of intraoperative handover personal errors."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2020
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Tania Khaerunnisa
Analisis asuhan keperawatan kesehatan masyarakat perkotaan pada pasien gagal jantung kongestif Tn. W dengan anesietas di Ruang Gayatri Rs. Dr. Marzoeki Mahdi Bogor = Analysis of Clinical Pratice of Urban Health Nursing in Congestive Heart Failure Patient Mr. W with Anxiety in Gayatri Room Dr. H. Marzoeki Mahdi Hospital Bogor
"[ABSTRAK
Penyakit kardiovaskular seperti gagal jantung kongestif memiliki prevalensi yang tinggi yang dapat disebabkan oleh perubahan pola hidup pada masyarakat urban. Kenaikan prevalensi penyakit kardiovaskular berhubungan dengan proses urbanisasi yang progresif dan globalisasi dari pola hidup tidak sehat yang ada pada masyarakat urban atau perkotaan. Tanda klinis yang muncul serta proses hospitalisasi dapat menjadi salah satu faktor munculnya masalah psikososial pada pasien gagal jantung kongestif. Masalah psikososial yang sering ditemukan adalah ansietas. Penulisan karya ilmiah ini bertujuan memberikan analisis mengenai asuhan keperawatan ansietas pada pasien gagal jantung kongestif. Intervensi yang dianalisis meliputi relaksasi napas dalam, hipnosis lima jari, distraksi sosialisasi dan pemberian informasi. Evaluasi tindakan menunjukan bahwa lebih banyak tanda gejala yang menghilang saat memberikan kombinasi tarik napas dalam dan hipnosis lima jari selama lima hari perawatan. ABSTRACT Cardiovascular disease such as congestive heart failure have high prevalence due to the transition of lifestyle in urban society. The increase of prevalence relates to the progressive and global urbanization which has unhealthy sedentary lifestyle in urban society. The presence of sign and symptom or hospitalization may cause the psychosocial problem in patient with CHF such as anxiety. The objective was to analyze the psychosocial nursing care plan specifically anxiety in CHF patient. Nursing intervention which has given are deep breathing relaxation, five finger hypnosis, distraction and health education. It shows that sign and symptom of anxiety decreased significantly when deep breathing and hypnosis is combined.;Cardiovascular disease such as congestive heart failure have high prevalence due to the transition of lifestyle in urban society. The increase of prevalence relates to the progressive and global urbanization which has unhealthy sedentary lifestyle in urban society. The presence of sign and symptom or hospitalization may cause the psychosocial problem in patient with CHF such as anxiety. The objective was to analyze the psychosocial nursing care plan specifically anxiety in CHF patient. Nursing intervention which has given are deep breathing relaxation, five finger hypnosis, distraction and health education. It shows that sign and symptom of anxiety decreased significantly when deep breathing and hypnosis is combined.;Cardiovascular disease such as congestive heart failure have high prevalence due to the transition of lifestyle in urban society. The increase of prevalence relates to the progressive and global urbanization which has unhealthy sedentary lifestyle in urban society. The presence of sign and symptom or hospitalization may cause the psychosocial problem in patient with CHF such as anxiety. The objective was to analyze the psychosocial nursing care plan specifically anxiety in CHF patient. Nursing intervention which has given are deep breathing relaxation, five finger hypnosis, distraction and health education. It shows that sign and symptom of anxiety decreased significantly when deep breathing and hypnosis is combined.;Cardiovascular disease such as congestive heart failure have high prevalence due to the transition of lifestyle in urban society. The increase of prevalence relates to the progressive and global urbanization which has unhealthy sedentary lifestyle in urban society. The presence of sign and symptom or hospitalization may cause the psychosocial problem in patient with CHF such as anxiety. The objective was to analyze the psychosocial nursing care plan specifically anxiety in CHF patient. Nursing intervention which has given are deep breathing relaxation, five finger hypnosis, distraction and health education. It shows that sign and symptom of anxiety decreased significantly when deep breathing and hypnosis is combined.;Cardiovascular disease such as congestive heart failure have high prevalence due to the transition of lifestyle in urban society. The increase of prevalence relates to the progressive and global urbanization which has unhealthy sedentary lifestyle in urban society. The presence of sign and symptom or hospitalization may cause the psychosocial problem in patient with CHF such as anxiety. The objective was to analyze the psychosocial nursing care plan specifically anxiety in CHF patient. Nursing intervention which has given are deep breathing relaxation, five finger hypnosis, distraction and health education. It shows that sign and symptom of anxiety decreased significantly when deep breathing and hypnosis is combined., Cardiovascular disease such as congestive heart failure have high prevalence due to the transition of lifestyle in urban society. The increase of prevalence relates to the progressive and global urbanization which has unhealthy sedentary lifestyle in urban society. The presence of sign and symptom or hospitalization may cause the psychosocial problem in patient with CHF such as anxiety. The objective was to analyze the psychosocial nursing care plan specifically anxiety in CHF patient. Nursing intervention which has given are deep breathing relaxation, five finger hypnosis, distraction and health education. It shows that sign and symptom of anxiety decreased significantly when deep breathing and hypnosis is combined.]"
Depok: Fakultas Farmasi Universitas Indonesia, 2015
PR-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Assifa Swasti Anindita
Analisis Determinan Kinerja Program Rujuk Balik Kasus Chronic Heart Disease Pasien BPJS Kesehatan RSU Hasanah Graha Afiah Tahun 2020 = Analysis of The Performance Determinants of The Referral Program for BPJS Kesehatan Patients with Chronic Heart Failure Case at RSU Hasanah Graha Afiah in 2020
"Latar belakang: Program Rujuk Balik merupakan program pelayanan kesehatan yang diberikan kepada peserta dengan penyakit kronis yang sudah stabil namun masih membutuhkan pengobatan jangka panjang. Evaluasi BPJS Kesehatan tahun 2018 menunjukkan bahwa RSU Hasanah Graha Afiah (HGA) memiliki 3511 pasien potensial PRB yang harus dikembalikan ke FKTP namun sampai dengan tahun 2020 RSU Hasanah Graha Afiah masih belum berhasil memenuhi target tersebut. Berdasarkan data 10 diagnosa terbanyak kunjungan instalasi rawat jalan RSU HGA tahun 2020, Chronic Heart Failure (CHF) menduduki peringkat no 1 dengan jumlah kunjungan 9667 kunjungan dan hanya 35 pasien CHF yang mengikuti PRB. Hasil kredensial RSU HGA tahun 2020 menunjukkan bahwa skor pencapaian PRB 100 % hanya 4.6 % sehingga terancam untuk tidak dapat melanjutkan kerja sama. Metode: Penelitian ini merupakan penelitian kuantitatif kasus kontrol dan kualitatif. Instrumen yang digunakan adalah kuisioner, formulir data klinis dan pedoman wawancara. Analisis dilakukan dengan melihat karakteristik, data klinis, pengetahuan, tingkat kepatuhan minum obat masing-masing kelompok dan mengetahui faktor-faktor yang mempengaruhi kinerja PRB serta pandangan informan tentang PRB. Hasil dan Kesimpulan: Pengetahuan tinggi memiliki OR sebesar 31.0 kali lebih besar (95% interval kepercayaan 7.0 – 136.9) untuk melakukan PRB dibandingkan dengan skor pengetahuan rendah setelah dikontrol oleh variabel lain. Hasil analisis kualitatif menunjukkan bahwa masih ada peserta BPJS Kesehatan yang belum paham mengenai PRB, tidak tersedianya obat-obatan di apotik rekanan, pelayanan di FKTP yang belum optimal dan tingkat kepercayaan peserta BPJS Kesehatan yang rendah terhadap FKTP menyebabkan PRB tidak berjalan dengan baik. Saran: Sosialisasi alur dan manfaat PRB bagi peserta BPJS Kesehatan, peningkatan pengetahuan DPJP mengenai kriteria stabil, peningkatan kualitas pelayanan di FKTP dan peningkatan kualitas pelayanan farmasi di apotik rekanan terutama ketersediaan obat-obatan bagi peserta PRB diharapkan dapat mengoptimalkan PRB.
Background: Referral Program (PRB) is a health service program that is provided to participants with chronic diseases who are stable but still require long-term treatment. The 2018 Health BPJS evaluation showed that RSU Hasanah Graha Afiah (HGA) had 3511 PRB potential patients who had to be returned to the FKTP but until 2020 RSU HGA had not yet succeeded in meeting this target. Based on data from the 10 diagnoses with the most outpatient visits at RSU HGA in 2020, Chronic Heart Failure (CHF) was ranked number 1 with 9667 visits and only 35 CHF patients took PRB. The results of the 2020 RSU HGA credential showed that the 100% PRB achievement score is only 4.6% so it is threatened not to be able to continue cooperation. Methods: This study is a quantitative case-control and qualitative study using a questionnaire instrument, clinical data form and interview. The analysis was conducted by looking at the characteristics, clinical data, knowledge and level of adherence to taking medication for each group and knowing the factors that affect the performance of PRB as well as informant outlook of PRB. Results and Conclusions: High knowledge has an OR of 31.0 times greater (95% confidence interval 7.0 – 136.9) for doing PRB compared to low knowledge scores after being controlled by other variables. The results of the qualitative analysis show that there are still BPJS Kesehatan participants who do not understand about PRB, the unavailability of medicines at partner pharmacies, FKTP services that are not optimal and the low level of trust of BPJS Kesehatan participants in FKTP causes PRB not to work well. Suggestion: Socialization flow and benefit of PRB for BPJS Kesehatan participants, DPJP knowledge improvement in stable criteria, improving service quality in FKTP and partner pharmacies especially in medicine availability hopefully will enhance PRB quality.
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Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2021
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
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William Sanjaya
Effect of beta blocker therapy on survival in severe heart failure
"Agen penghambat beta telah menunjukkan penurunan resiko perawatan atau kematian pasien dengan gagal jantung ringan sampai sedang, tetapi hanya sedikit diketahui mengenai manfaat atau keamanan agen ini pada gagal jantung berat. Dilaporkan satu kasus penggunaan penghambat beta pada gagal jantung berat dengan fraksi ejeksi kurang dari 25%. Laporan manfaat penghambat beta terhadap kesakitan dan kematian pasien dengan gagal jantung ringan sampai sedang juga ditemukan pada pasien dengan gagal jantung berat seperti yang dilaporkan pada kasus ini. (Med J Indones 2002; 11: 174-5)
Beta-blocking agents have been shown to reduce the risk of hospitalization and death in patients with mild to moderate heart failure, but little is known about the efficacy or safety of these agents in severe heart failure. A case of beta blocker administration in severe heart failure with ejection fraction less than 25% is reported. The reported benefits of beta blockers with regard to morbidity and mortality in patients with mild to moderate heart failure were also found in the patient with severe heart failure as reported in this case. (Med J Indones 2002; 11: 174-5)"
Medical Journal of Indonesia, 2002
MJIN-11-3-JulSep2002-174
Artikel Jurnal  Universitas Indonesia Library
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Kaawoan, Adeleida Yuliana Anita
Hubungan self care dan depresi dengan kualitas hidup pasien Heart Failure di RSUP Prof DR R.D Kandou Manado = The correlation between self care and depression with kualitas hidup heart failure patient in Prof DR. R.D Kandou Hospital Manado
"Heart Failure (HF) merupakan sindrom klinis akibat ketidakmampuan jantung memompakan darah untuk memenuhi kebutuhan oksigen dan nutrisi jaringan tubuh. Kondisi ini menyebabkan keterbatasan fungsional dan distress psikologis yang berefek pada kualitas hidup pasien.
Penelitian ini bertujuan untuk mengetahui hubungan self care dan depresi dengan kualitas hidup pasien heart failure di RSUP Prof Dr R.D Kandou Manado. Desain penelitian desain non eksperimental jenis cross sectional analitik. Responden sebanyak 79 orang, diperoleh melalui teknik consecutive sampling.
Hasil penelitian menunjukkan terdapat hubungan yang signifikan antara self care dan depresi dengan kualitas hidup pasien HF. Selain itu didapatkan variabel umur, self care dan depresi merupakan faktor dominan yang berhubungan dengan kualitas hidup. Implikasi hasil penelitian dalam keperawatan adalah peningkatan peran perawat sebagai edukator dengan memberikan pendidikan kesehatan tentang self care dan mengembangkan kemampuan dalam melakukan screening tingkat depresi pasien HF secara rutin.
Heart Failure (HF) is a clinical syndrome of inability of the heart to provide sufficient pump action to distribute blood flow to meet the needs of the body. This situation creates functional limitations and psychological distress that give impact on patient?s kualitas hidup (QoL).
The purpose of this research was to identify correlation between self care and depression with kualitas hidup heart failure patient in Prof DR. R.D Kandou Hospital Manado. This study used nonexperimental analytic cross sectional design. Seventy nine respondents was recruited using consecutive sampling method.
The study finding showed significant correlation between self care and depression with kualitas hidup heart failure patient. In addition age, self care and depression are found as predominant factors to kualitas hidup of heart failure patient. Nursing implication from this result is that of nursing role as educator on self care and ability in screening patient?s depression level should be improved."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2012
T30728
UI - Tesis Open  Universitas Indonesia Library
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Ni Luh Gede Intan Saraswati
Pengaruh deep breathing exercise terhadap kualitas tidur pasien gagal jantung = The effect of deep breathing exercise for sleep quality in heart failure patient / Ni Luh Gede Intan Saraswati
"ABSTRAK
Pengaruh Deep Breathing Exercise terhadap Kualitas Tidur Pasien Gagal Jantung Gangguan tidur merupakan salah satu gejala pada pasien gagal jantung. Tidur yang buruk berimplikasi negatif pada kesehatan psikologis, fisiologis, kualitas hidup, pasien gagal jantung. Deep breathing exercise menjadi intervensi keperawatan yang dapat memperbaiki kualitas tidur. Penelitian bertujuan untuk mengidentifikasi pengaruh deep breathing exercise terhadap kualitas tidur pasien gagal jantung. Rancangan penelitian menggunakan quasy experiment pre-post with control group. Besar sampel sebanyak 34 subjek sebagai kelompok kontrol dan perlakuan. Terdapat perubahan yang signifikan pada kelompok perlakuan sebelum dan sesudah intervensi p=0,001 , dan tidak ada perubahan yang signifikan antara kelompok kontrol dan perlakuan setelah intervensi. Walaupun demikian terjadi perubahan nilai kualitas tidur yang lebih baik pada kelompok intervensi, sehingga teknik deep breathing exercise ini dapat diberikan pada pasien gagal jantung. Kata kunci: deep breathing exercise, gagal jantung, kualitas tidur.
ABSTRACT
The Effect of Deep Breathing Exercise for Sleep Quality in Heart Failure Patient THE EFFECT OF DEEP BREATHING EXERCISE FOR SLEEP QUALITY IN HEART FAILURE PATIENT Sleep disorder is one of the symptom among heart failure patients. The Poor sleep quality has negative impact for the psychological, physiological, quality of life in heart failure patients. Deep breathing exercise is a nursing intervention to improve sleep quality. This study aim to identify the effect of deep breathing exercise among heart failure patients. This study used quasy experiment pre post test with control group design. This study recruited 34 subjects as control and treatment group. The result of the study showed that quality of sleep was improved significantly after deep breathing exercise was implemented in treatment group p 0,001 , but there was no significant difference between control and treatment group after deep breathing exercise. However deep breathing exercise is recommended as nursing intervention to improve the quality of sleep among heart failure patient because the change of sleep quality in treatment group is better than control group Keywords deep breathing exercise, heart failure, quality of sleep"
2017
T47167
UI - Tesis Membership  Universitas Indonesia Library
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Maha Fitra Nd
Efek empagliflozin terhadap fibrosis miokard pada pasien diabetes melitus tipe 2 dengan gagal jantung = Effects of empagliflozin on myocardial fibrosis in patients with type 2 diabetes mellitus and heart failure
"Latar belakang: Diabetes mellitus tipe 2 (DMT2) dan gagal jantung memiliki keterkaitan yang kuat dan luaran klinis yang satu mempengaruhi lainnya. Studi terakhir berhasil membuktikan manfaat empagliflozin, obat lini kedua pada DMT2, terhadap kardiovaskular. Mekanisme seluler yang diketahui berperan pada hewan adalah efek antifibrosis miokard, namunbelum ada studi pada manusia.Tujuan: Mengetahui efek pemberian empagliflozin terhadap fibrosis miokard pada pasien DMT2 dengan gagal jantung. Metode: Uji klinis acak tidak tersamar yang dilakukan di RS Jantung dan Pembuluh Darah Harapan Kita dari Februari 2019 sampai Mei 2019. Pasien DMT2 dan gagal jantung diberikan empagliflozin 10 mg selama tiga bulan. Perbedaan kadar suppression of tumorigenicity-2 (ST2) serum pada kelompok kontrol dan intervensi di awal dan akhir penelitian akan dianalisis. Hasil: Terdapat 58 pasien yang menjadi subjek penelitian dan 40 (69%) pasien menyelesaikan penelitian. Terdapat perbedaan kadar ST2 yang bermakna setelah pemberian empagliflozin selama tiga bulan (median ST2 kelompok empagliflozin sebelum dan sesudah empagliflozin masing-masing 23,5(12,5 - 130,7)ng/mL dan 18,9(12,5 - 29,4) ng/mL, p=0,02). Penurunan ST2 dan persentase penurunan ST2 kelompok empagliflozin kedua kelompok tidak berbeda secara statistik (masing-masing p=0,16 dan p=0,21). Kesimpulan: Pemberian empagliflozin selama tiga bulan dapat menurunkan fibrosis miokard yang tidak terlihat pada kelompok kontrol. Tidak terdapat perbedaan besaran penurunan fibrosis pada pemberian empagliflozin dibandingkan terapi standar.
Background: Type 2 diabetes mellitus (T2DM) and heart failure have a strong relationship; one affects each other. Recent studies have proven some cardiovascular benefits of empagliflozin. Myocardial antifibrosis is proposed to be the mechanism in many animal studies, but in humans the data is lack. Objectives: To investigate the effect of empagliflozin on myocardial fibrosis in T2DM patients and heart failure. Methods: This was an open-labeled clinical trial in National Cardiovascular Center Harapan Kita, from February 2019 to May 2019. Patients with T2DM and heart failure received empagliflozin 10 mg for three months. Differences of serum suppression of tumorigenicity-2 (ST2) levels in both control and intervention groups at the beginning and end of the study were analyzed. Results: There were 58 patients enrolled in the study and total of 40 (69%) patients completed it. There were significant differences in ST2 levels after administration of empagliflozin (median for ST2 empagliflozin group before and after empagliflozin was 23.5 (12.5 - 130.7) ng / mL and 18.9 (12, 5 - 29.4) ng / mL respectively, p = 0.02). The ST2 value difference and percent different were not different (p=0,16 and p=0,21, respectively). Conclusion: Three months Empagliflozin might reduce myocard fibrosis which was not seen in control group. The total fibrosis reduction was not significantly different compared to standard therapy"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2019
T59208
UI - Tesis Membership  Universitas Indonesia Library
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Rizki
Challenges on management of heart failure in indonesia: a general practitioner perspective
"Abstrak
Heart failure has become a public health problem with increasing incidence and prevalence. Many patients first came to the primary care and managed by general practitioner. Accurate diagnosis is essential to provide good management of heart failure. However, symptoms and signs alone are often neither sufficient nor specific to confirm the diagnosis. Some studies show that heart failure patients are still incorrectly diagnosed and inadequately treated, despite the availability of current guidelines. Inadequacy of facilities is the main obstacle in diagnosing and managing heart failure, especially in developing countries like Indonesia. The medications recommended for treating heart failure are still under-prescribed. This review discuss about the challenges of diagnosis and management of heart failure in primary care."
Jakarta: Faculty of Medicine Universitas Indonesia, 2014
610 UI- MJI 23:1 (2014) (2)
Artikel Jurnal  Universitas Indonesia Library
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