Fitriani Annisa A.M.
Abstrak :
[ABSTRAK
Menstruasi yang menimbulkan nyeri merupakan salah satu masalah ginekologi
yang paling umum dialami wanita dari berbagai tingkat usia. Manajemen untuk
mengatasi nyeri saat haid diantaranya adalah dengan mengonsumsi obat pereda
nyeri haid. Saat ini masyarakat mulai beralih untuk menggunakan tanaman obat
sebagai obat alternatif analgesik, diantaranya tanaman jahe merah merah
(Zingiber officinale var. Rubrum) dan cengkeh (Syzigium aromaticum). Penelitian
ini bertujuan untuk mengetahui pengaruh sediaan krim campuran minyak jahe
merah (Zingiber officinale var. Rubrum) dan minyak cengkeh (Syzigium
aromaticum) terhadap penurunan intensitas nyeri haid primer. Minyak jahe merah
dan minyak cengkeh dibuat menjadi sediaan krim dengan konsentrasi berturutturut
5% dan 3%. Uji stabilitas fisik sediaan krim dilakukan selama 12 minggu
dan uji keamanan kepada relawan menggunakan metode uji tempel. Uji manfaat
dilakukan selama 3 jam pada area abdomen bagian bawah. Sediaan krim
menunjukkan kestabilan selama 12 minggu dan hasil uji keamanan tidak
menimbulkan iritasi sehingga aman digunakan secara topikal. Hasil uji manfaat
diukur dengan parameter Visual Analogue Scale, Wong-Baker Faces Pain Rating
Scale, frekuensi denyut nadi radialis, frekuensi pernapasan, menunjukkan sediaan
krim uji mampu menurunkan intensitas nyeri haid primer. Krim uji memberikan
pengaruh penurunan intensitas nyeri yang berbeda nyata dibandingkan krim
plasebo, yaitu pada pemakaian krim setelah 3 jam.
ABSTRACT
Painful menstruation is one of the most common gynecological problems
experienced by women of all ages. To overcome the pain during menstruation is
by taking pain medication during menstruation. Nowadays , people are start to use
herb as an alternative analgesic medicine, including red ginger plant (Zingiber
officinale var.Rubrum) and cloves (Syzigium aromaticum). This research aims to
determine the effect of mixture cream between red ginger oil (Zingiber officinale
var . Rubrum) and clove oil ( Syzigium aromaticum) to reduce the intensity of
primary Dysmenorrhea. Oil of red ginger and clove oils are made into cream with
a concentration respectively 5% and 3%. Physical stability test for creams
conducted over 12 weeks and safety testing to volunteers using the patch test.
Benefit test carried out for 3 hours at the lower abdominal area. Formulations
cream showed stability during 12 weeks and the results of safety test does not
cause irritation which make safe to use topically. Benefit test results measured by
Visual Analogue Scale parameter, Wong- Baker Faces Pain Rating Scale, the
frequency of the radial pulse and respiratory rate, it shows the test cream capable
of lowering the intensity of the primary dysmenorrhea. Test creams is able to
decrease pain intensity and was significantly different compared to placebo cream
where each effect of the cream is observed after 3 hours;Painful menstruation is one of the most common gynecological problems
experienced by women of all ages. To overcome the pain during menstruation is
by taking pain medication during menstruation. Nowadays , people are start to use
herb as an alternative analgesic medicine, including red ginger plant (Zingiber
officinale var.Rubrum) and cloves (Syzigium aromaticum). This research aims to
determine the effect of mixture cream between red ginger oil (Zingiber officinale
var . Rubrum) and clove oil ( Syzigium aromaticum) to reduce the intensity of
primary Dysmenorrhea. Oil of red ginger and clove oils are made into cream with
a concentration respectively 5% and 3%. Physical stability test for creams
conducted over 12 weeks and safety testing to volunteers using the patch test.
Benefit test carried out for 3 hours at the lower abdominal area. Formulations
cream showed stability during 12 weeks and the results of safety test does not
cause irritation which make safe to use topically. Benefit test results measured by
Visual Analogue Scale parameter, Wong- Baker Faces Pain Rating Scale, the
frequency of the radial pulse and respiratory rate, it shows the test cream capable
of lowering the intensity of the primary dysmenorrhea. Test creams is able to
decrease pain intensity and was significantly different compared to placebo cream
where each effect of the cream is observed after 3 hours, Painful menstruation is one of the most common gynecological problems
experienced by women of all ages. To overcome the pain during menstruation is
by taking pain medication during menstruation. Nowadays , people are start to use
herb as an alternative analgesic medicine, including red ginger plant (Zingiber
officinale var.Rubrum) and cloves (Syzigium aromaticum). This research aims to
determine the effect of mixture cream between red ginger oil (Zingiber officinale
var . Rubrum) and clove oil ( Syzigium aromaticum) to reduce the intensity of
primary Dysmenorrhea. Oil of red ginger and clove oils are made into cream with
a concentration respectively 5% and 3%. Physical stability test for creams
conducted over 12 weeks and safety testing to volunteers using the patch test.
Benefit test carried out for 3 hours at the lower abdominal area. Formulations
cream showed stability during 12 weeks and the results of safety test does not
cause irritation which make safe to use topically. Benefit test results measured by
Visual Analogue Scale parameter, Wong- Baker Faces Pain Rating Scale, the
frequency of the radial pulse and respiratory rate, it shows the test cream capable
of lowering the intensity of the primary dysmenorrhea. Test creams is able to
decrease pain intensity and was significantly different compared to placebo cream
where each effect of the cream is observed after 3 hours]
2015
T43642
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