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Abstrak :
ABSTRAK
Odontocem® dan Biodentine®, berbahan dasar kalsium silikat. Tetapi terdapat kandungan lain yang mungkin memiliki efek pada viabiltas sel. Contohnya penambahan steroid dalam Odontocem®. Belum diketahui apakah penambahan steroid tersebut memiliki efek atau tidak terhadap viabilitas sel. Sel fibroblas yang diambil dari Telur Embrio Tertunas (TET), dipajan dengan Odontocem® dan Biodentine® dengan jumlah masing-masing kelompok sebesar 15 well. Kemudian viabilitas sel diukur selama 24 jam dan 72 jam. Hasil penelitian diuji dengan uji statistik Kruskal Wallis dengan uji post hoc Mann-Whitney. Berdasarkan hasil penelitian, didapatkan bahwa Odontocem® dan Biodentine® memiliki efek menurunkan viabiltas sel fibroblas pada pengukuran 24 jam dan 72 jam. Juga viabilitas sel fibroblas pada kelompok perlakuan Odontocem ® lebih tinggi daripada Biodentine® baik pada pengukuran 24 jam maupun 72 jam. ABSTRACT
Odontocem® and Biodentine®, both consist of calcium silicate. But there are other substances which may have an effect on cell viability. For example, addition of steroids in Odontocem®. It is not yet known whether these steroids have an effect or not on the cell viability. Fibroblasts taken from Chicken Embryo, added with Odontocem® and Biodentine® by each group of 15 wells. Then the cell viability was measured for 24 hours and 72 hours. The result were tested by Kruskal Wallis statistical test with post hoc test of Mann-Whitney. Based on this research, it was found that Odontocem® and Biodentine® have a lowering effect on the fibroblast cell viability for 24 hours and 72 hours. Thus, fibroblast cell viability the treatment group Odontocem ® is higher than both the measurement Biodentine® 24 hours or 72 hours.;Odontocem® and Biodentine®, both consist of calcium silicate. But there are other substances which may have an effect on cell viability. For example, addition of steroids in Odontocem®. It is not yet known whether these steroids have an effect or not on the cell viability. Fibroblasts taken from Chicken Embryo, added with Odontocem® and Biodentine® by each group of 15 wells. Then the cell viability was measured for 24 hours and 72 hours. The result were tested by Kruskal Wallis statistical test with post hoc test of Mann-Whitney. Based on this research, it was found that Odontocem® and Biodentine® have a lowering effect on the fibroblast cell viability for 24 hours and 72 hours. Thus, fibroblast cell viability the treatment group Odontocem ® is higher than both the measurement Biodentine® 24 hours or 72 hours.

Abstrak :
ABSTRAK
Latar Belakang: MTA bersifat biokompatibel dan dapat digunakan untuk perawatan kaping pulpa. Saat ini dikembangkan semen berbasis kalsium silikat sama seperti MTA dengan penambahan steroid, yaitu Odontocem. Tujuan:Membandingkan efek toksisitas odontocem dan MTA-Angelus terhadap viabilitas sel fibroblas. Metode:Sel fibroblast embrio ayam direndam dalam larutan odontocemdan dan MTA-Angeluspada 24 dan 72 jam. Viabilitas sel dihitung menggunakanMTT Assay. Hasil:Pada kelompok odontcemdan MTA-Angelus, terdapat perbedaan bermakna (p≤0,05 ) dibandingkan dengan kontrol. Pada paparan 24 jam, tidak terdapat perbedaan bermakna antara odontocem dengan MTA-Angelus. Kesimpulan:Odontocem dan dan MTA-Angelus menurunkan viabilitas sel pada 24 jam dan meningkatkan pada 72 jam.ABSTRACT
Background:MTA is proved tobe biocompatible and can be used for pulp capping treatment.Currently, calcium silicate based cement similar to MTA with steroid,called Odontocem has been developed.Objective:To compare effects of odontocem and MTA-Angelus toxicity towards fibroblast cells viability.Method:Fibroblast cells of chicken embryonic were immersed separately in odontocem and MTA-Angelus solution for 24 and 72 hours.Cells viability was analyzed with MTT Assay.Result:There was a significant difference (p>0.05) in Odontocem and MTA-Angelus group compared to control.At the24-hour immersion, there was nosignificant difference between odontocem and MTA-Angelus.Conclusion:Odontocem and MTA-Angelus decreased the viability of fibroblast at 24 hours and increased them at 72 hours.;Background:MTA is proved tobe biocompatible and can be used for pulp capping treatment.Currently, calcium silicate based cement similar to MTA with steroid,called Odontocem has been developed.Objective:To compare effects of odontocem and MTA-Angelus toxicity towards fibroblast cells viability.Method:Fibroblast cells of chicken embryonic were immersed separately in odontocem and MTA-Angelus solution for 24 and 72 hours.Cells viability was analyzed with MTT Assay.Result:There was a significant difference (p>0.05) in Odontocem and MTA-Angelus group compared to control.At the24-hour immersion, there was nosignificant difference between odontocem and MTA-Angelus.Conclusion:Odontocem and MTA-Angelus decreased the viability of fibroblast at 24 hours and increased them at 72 hours.;Background:MTA is proved tobe biocompatible and can be used for pulp capping treatment.Currently, calcium silicate based cement similar to MTA with steroid,called Odontocem has been developed.Objective:To compare effects of odontocem and MTA-Angelus toxicity towards fibroblast cells viability.Method:Fibroblast cells of chicken embryonic were immersed separately in odontocem and MTA-Angelus solution for 24 and 72 hours.Cells viability was analyzed with MTT Assay.Result:There was a significant difference (p>0.05) in Odontocem and MTA-Angelus group compared to control.At the24-hour immersion, there was nosignificant difference between odontocem and MTA-Angelus.Conclusion:Odontocem and MTA-Angelus decreased the viability of fibroblast at 24 hours and increased them at 72 hours.;Background:MTA is proved tobe biocompatible and can be used for pulp capping treatment.Currently, calcium silicate based cement similar to MTA with steroid,called Odontocem has been developed.Objective:To compare effects of odontocem and MTA-Angelus toxicity towards fibroblast cells viability.Method:Fibroblast cells of chicken embryonic were immersed separately in odontocem and MTA-Angelus solution for 24 and 72 hours.Cells viability was analyzed with MTT Assay.Result:There was a significant difference (p>0.05) in Odontocem and MTA-Angelus group compared to control.At the24-hour immersion, there was nosignificant difference between odontocem and MTA-Angelus.Conclusion:Odontocem and MTA-Angelus decreased the viability of fibroblast at 24 hours and increased them at 72 hours.