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Ditemukan 14 dokumen yang sesuai dengan query
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Miller, Carol A.
Philadelphia: Lippincott Williams & Wilkins, 2004
618.970 231 MIL n
Buku Teks  Universitas Indonesia Library
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Stefanus Mendes Kiik
Abstrak :
ABSTRAK
Gangguan keseimbangan tubuh merupakan salah masalah kesehatan yang sering dialami oleh lansia. Masalah ini dapat mengakibatkan jatuh dan cedera bila tidak dicegah. Model intervensi cegah gangguan keseimbangan tubuh (Cegat lansia) merupakan bentuk intervensi keperawatan komunitas yang dapat mempertahankan keseimbangan tubuh lansia. Penulisan bertujuan memberikan gambaraan pelaksanaan model intervensi keperawatan komunitas “cegat lansia” untuk mempertahankan keseimbangan tubuh dalam pelayanan keperawatan komunitas melalui integrasi teori dan model community as partner, family center nursing, konsekuensi fungsional dan fungsi manajemen pada kelompok lansia dengan gangguan keseimbangan di Kelurahan Srengseng Sawah, Jakarta Selatan. Hasil intervensi menunjukkan model intervensi cegat lansia berpengaruh signifikan dalam meningkatkan keseimbangan tubuh (p=0,000), pengetahuan (p=0,000), sikap (p=0,000) dan keterampilan (p=0,000). Model intervensi ini dapat meningkatkan keseimbangan tubuh pada lansia di komunitas. Hal ini memberi peluang bagi perawat kesehatan komunitas dalam pengembangan intervensi promotif dan preventif. Model intervensi ini aman, mudah, efektif dan murah bagi lansia di komunitas.
ABSTRACT
Balance impairment is one of health problem among older adults. This problem can lead to falls and injuries if not prevented. The intervention model to prevent balance impairment (as known as cegat lansia) is a community nursing intervention to maintain the postural balance among older adults. This report aimed to provide an overview of the implementation of nursing intervention and services project through the integration of the community as partner, family center nursing, functional concequences, and management function among older adults with balance impairment in Srengseng Sawah South Jakarta. The results of intervention showed cegat lansia intervention have a significant effect in improving the postural balance (p = 0.000), knowledge (p = 0.000), attitude (p = 0.000) and skills (p = 0.000). It concludes that the intervention model can improve postural balance among older adults in the community. That gives an opportunity for community health nurses to develop promotive and preventive interventions. It concludes that this intervention model for older adults is safe, easy, effective and inexpensive to older adults in the community.
2016
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Abd. Rahman Hamid, 1982-
Abstrak :
ABSTRAK
Masalah yang cukup kompleks dan kerap terjadi pada lansia adalah gangguan fungsi psikososial dimana hal ini terjadi karena fungsi psikososial mendapatkan stressor yang cukup besar dan tidak mampu menemukan penyelesaian dari sumber stressor tersebut. Tujuan penelitian ini adalah menggambarkan pelaksanaan intervensi Latihan Jalan AkTif terhadap peningkatan fungsi psikososial di Kota Depok. Penerapan implementasi ini merupakan menggunakan evidence based practice. Pengambilan sampel dilakukan dengan cara consecutive sampling. Analisis data menggambarkan karakteristik responden, peningkatan rerata pengetahuan, sikap dan keterampilan. Analisis Statistik menggunakan uji paired t test didapatkan p value 0,000 untuk dampak negatif psikososial DASS dan 0,004 pada fungsi intelektual SPMSQ pada lansia. Latihan Jalan AkTif dapat meningkatkan fungsi psikososial pada lansia secara signifikan. Disarankan agar latihan ini dapat diterapkan dalam rangka pemberian asuhan keperawatan pada lansia secara rutin dan terjadwal.
ABSTRACT
The complicated problems and often occurs in the older adult is a disruption of psychosocial function where this happens because psychosocial function get a big enough stressor and unable to find a solution from the source of the stressor. The purpose of this study is to describe the implementation of Jalan AkTif Exercise interventions to improve psychosocial function in Depok City. This study uses the evidence based practice. Sampling is done by consecutive sampling. Data analysis describes the characteristics of respondents, improvement average by knowledge, attitude and skill. Statistical analysis using paired t test obtained p value 0,000 for negative psychosocial impact DASS and 0,004 on intellectual function SPMSQ in elderly. Jalan AkTif Exercise can significantly improve the psychosocial function of the older people. It is recommended that this exercise be applicable in order to provide nursing care to the older adult regularly. Key words walking and cognitive Exercise, older adults
2017
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Thika Marliana
Abstrak :
Depresi pada lansia Indonesia memiliki prevalensi sebesar 7,7%, lebih tinggi daripada kelompok usia yang lebih muda secara nasional yaitu 6,1%, namun tindakan untuk mengatasinya belum optimal karena asuhan yang diberikan belum holistik dan tidak terintegrasi dengan program maupun sektor layanan lainnya. Pengembangan model tindakan holistik integratif kesehatan jiwa merupakan salah satu upaya dalam menurunkan depresi pada lansia dengan meningkatkan perkembangan psikososial dan kebahagiaan lansia melalui optimalisasi sumber daya yang ada di masyarakat. Tujuan penelitian ini menguji efektifitas model tindakan holistik integratif kesehatan jiwa terhadap perkembangan psikososial dan kebahagiaan lansia depresi. Desain operational research diterapkan menjadi 3 tahap yaitu: 1) Tahap eksplorasi pada 452 sampel kuantitatif dan 27 partisipan kualitatif, 2) Tahap pengembangan model, dan 3) Tahap uji efektifitas model menggunakan studi true experiment dengan randomisasi dan matching pada 122 responden. Hasil penelitian tahap pertama didapatkan gambaran masalah kesehatan jiwa lansia yaitu GME 67,5 % dan 58,7% diantaranya mengalami depresi, serta teridentifikasi 8 tema, yaitu: Sindrom sarang kosong sebagai killer silent lansia depresi; Kegelisahan dalam interaksi sosial karena social approval addiction; Kurangnya apresiasi masa sekolah dan remaja pada lansia depresi; Cabin fever memperburuk depresi; Love language sumber kepuasan lansia deprei: Self-healing untuk mengurangi luka masa lalu; Stimulus fisik dan mental untuk kesehatan jiwa lansia depresi yang holistik; dan Kemudahan akses pelayanan kesehatan jiwa lansia yang terintegrasi. Hasil penelitian tahap kedua tersusunnya model Tindakan Holistik Integratif Kesehatan jiwa (THIKA) pada lansia depresi. Hasil tahap 3 uji efektifitas model THIKA yang diberikan secara synchronous berpengaruh secara bermakna terhadap pencapaian perkembangan psikososial (integritas diri), peningkatan kebahagiaan, penurunan tingkat depresi dan kortisol. Hasil analisis GLM menunjukkan: Faktor yang paling mempengaruhi perkembangan psikososial adalah intervensi model THIKA, perkembangan sebelumnya dan indeks kebahagiaan sebesar 89,9%; Faktor yang paling mempengaruhi indeks kebahagiaan yaitu intervensi model THIKA, status mental, status fungsional, dan status nutrisi sebesar 90,01%; Faktor yang paling mempengaruhi tingkat depresi yaitu intervensi model THIKA, dan perkembangan psikososial sebesar 57,1%; Faktor yang paling mempengaruhi tingkat kortisol yaitu intervensi model THIKA, status nutrisi dan status fungsional sebesar 43,6%. Rekomendasi menggunakan model THIKA diperlukan untuk tindakan kesehatan jiwa oleh tenaga kesehatan, kader dan keluarga pada lansia sehingga active ageing dapat dicapai optimal. ......Depression in older adults in Indonesia has a prevalence of 7.7%, higher than the younger age group nationally, which is 6.1%. Still, measures to overcome it are not optimal because the care provided is not holistic or integrated with other programs or services sectors. Developing a mental health integrative holistic intervention model is an effort to reduce depression in older adults by increasing psychosocial development and happiness by optimizing existing community resources. This study aimed to test the effectiveness of a holistic, integrative mental health intervention model on psychosocial developmental tasks and happiness in the older adults depression. The operational research design was implemented into three phases: 1) The exploratory stage used 452 quantitative samples and 27 qualitative participants, 2) The model development stage, and 3) The model effectiveness test phase used a true-experiment study with randomization and matching on 122 respondents. The results of the first stage of the study showed an overview of elderly mental health problems, namely GME 67.5% and 58.7% of them experienced depression, and eight themes were identified: Empty-nest syndrome as a silent killer; Anxiety in social interactions due to social approval addiction; Lack of appreciation of school age and adolescence phase; Cabin fever exacerbates depression; Love language is a source of satisfaction for depressed older adults: Self-healing to reduce inner-child; Physical and mental stimulus for holistic mental health intervention; and The integrated mental health services accesibility. The results of the second study's phase were the formulation of a holistic, integrative mental health intervention model (THIKA) for depressed older adults. The final results of the effectiveness test of the THIKA model given synchronously had a significant effect on achieving psychosocial development (self-integrity), increasing happiness, decreasing levels of depression and cortisol. The results of the GLM analysis showed: The factors that most influence psychosocial development are the THIKA model intervention, previous development and happiness index by 89,9%; The factors that most influence the happiness index are the THIKA model intervention mental status, functional status, and nutritional status by 90,01%; The factors that most influence the level of depression are the THIKA model intervention and psychosocial development by 57,1%; The factors that most influence cortisol levels are the THIKA model intervention, nutritional status and functional status by 43,6%. Recommendations for using the THIKA model are needed for mental health intervention by health workers, cadres and families for older adults to achieve active ageing optimally.
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2023
D-pdf
UI - Disertasi Membership  Universitas Indonesia Library
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Metha Bhalkis Irianti
Abstrak :
Penelitian ini dilakukan untuk mengetahui hubungan antara persepsi diri terhadap proses penuaan dan persepsi terhadap kepuasan hidup pada individu lanjut usia di Depok. Pengukuran dilakukan dengan menggunakan alat ukur Attitudes Toward Own Aging (ATOA) yang dikembangkan oleh Liang dan Bollen (1983) berdasarkan lima item dari Philadephia Geriatric Center Morale Scale (Lawton, 1975) untuk mengukur persepsi diri terhadap proses penuaan dan Life Satisfaction Index A dari Indriani (2012) digunakan untuk mengukur persepsi terhadap kepuasan hidup. Penelitian ini melibatkan 100 partisipan lanjut usia terdiri dari 51 orang laki-laki (51%) dan 49 orang perempuan (49%). Berdasarkan pengolahan data menggunakan teknik statistik Pearson Product Moment, ditemukan bahwa persepsi diri terhadap penuaan berkorelasi positif dan signifikan dengan kepuasan hidup (r = 0.594; n=100; p < 0.01, one-tailed). Hasil penelitian ini menunjukkan bahwa persepsi diri terhadap penuaan berhubungan secara positif dan signifikan dengan kepuasan hidup. Artinya, semakin positif persepsi diri terhadap penuaan maka semakin tinggi pula kepuasan hidup pada individu lanjut usia. ......The objective of the present study is to investigate the correlation between self-perception of aging process and perception of life satisfaction on Elders in Depok. Self-perception of aging process is measured with the Attitude Toward Own Aging (ATOA) (Liang & Bollen, 1983) based on 5-item of Philadelphia Geriatric Center Morale Scale (Lawton, 1975) and Perception of Life Satisfaction is measured with Life Satisfaction Index A (Indriani, 2012). 100 older adults which consists of 51 (51%) male older adults and 49 (49%) female older adults are participated in this study. The result of this study shows that self-perception of aging is significantly correlated with life satisfaction of the older adults. This result means that the older adults who have positive self-perception of aging will have higher life satisfaction.
Depok: Fakultas Psikologi Universitas Indonesia, 2016
S62943
UI - Skripsi Membership  Universitas Indonesia Library
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Lazuardhi Dwipa
Abstrak :
ABSTRAK
Latar Belakang : Aphanizomenon Flos Aquae merupakan suatu spesies ganggang biru-hijau yang dimanfaatkan sebagai suplemen nutrisi di seluruh dunia termasuk di Indonesia dan diketahui memiliki banyak aktivitas biologis bermanfaat seperti efek anti-inflamasi, anti-oksidan dan analgetik. Osteoartritis (OA) lutut merupakan permasalahan yang cukup sering didapatkan pada lanjut usia (lansia) namun sampai saat ini belum tersedia modalitas farmakologik sebagai terapi ajuvan yang sesuai dan aman pada kelompok lansia. Aphanizomenon Flos Aquae dapat menjadi alternatif yang baik sebagai terapi ajuvan dalam tatalaksana pasien lansia dengan OA lutut. Tujuan Penelitian : Mengkaji pengaruh AFA terhadap perbaikan klinis OA lutut pada lansia berdasarkan indeks WOMAC. Metode : Dilakukan uji klinis acak tersamar ganda mulai November 2014 hingga Mei 2015 terhadap pasien lanjut usia dengan OA lutut di poliklinik Geriatri dan Reumatologi di RSUP Hasan Sadikin Bandung. Subjek dibagi menjadi 2 kelompok yaitu satu kelompok mendapat kapsul berisi AFA 2 kali 2 kapsul (1,28 g/hari) dan kelompok lainnya mendapat plasebo selama 60 hari. Skor Indeks WOMAC dinilai pada hari ke-1 dan hari ke-60 untuk menilai luaran klinis pasien OA. Perbedaan skor indeks WOMAC pada akhir penelitian dianalisis dengan uji Mann-Whitney. Hasil : Dari total 254 subjek didapatkan 98 subjek yang memenuhi kriteria awal penelitian dan kemudian dilakukan randomisasi menjadi kelompok perlakuan dan plasebo, masing-masing terdiri dari 49 subjek. Kedua kelompok sebanding pada seluruh faktor prognostik penting. Setelah analisis, skor indeks WOMAC komposit kelompok AFA berbeda secara bermakna (p<0,001) dibanding plasebo pada akhir penelitian dengan masing-masing skor 8 (median,RIK 3-18) vs. 18 (median,RIK 8-32). Tidak ditemukan adanya efek samping yang serius selama penelitian. Simpulan : Aphanizomenon Flos Aquae dapat memperbaiki klinis berdasarkan skor indeks WOMAC serta aman diberikan pada pasien lansia dengan OA lutut.
ABSTRACT
Background: Aphanizomenon Flos Aquae is a species of blue-green algae which is commonly used as nutritional supplement in the world, including in Indonesia and is known to have many beneficial biological activities such as antiinflammatory, anti-oxidant and analgesics. Osteoarthritis (OA) knee is a problem that is quite common in the older people but until now there has not been pharmacologic modalities as a adjunctive therapy available which are suitable and safe. Aphanizomenon Flos Aquae may become a good alternative as an adjunctive therapy in older patients with knee OA. Objective : To determine the effect of AFA on the improvement of clinical outcome of Knee OA in older patients based on WOMAC index scores. Methods : A double-blind randomized clinical trial was conducted from November 2014 until May 2015 to older adult patients with Knee OA at the Geriatric and Rheumatology clinic in Hasan Sadikin General Hospital. The subjects were divided into groups, each group received capsules containing AFA 2 times 2 capsules (1.28 gr/day) and the other received placebo for 60 days. WOMAC Index scores were assessed at day 1 and day 60. The difference in assessment of WOMAC index scores of each group at the end of the study were analyzed by Mann-Whitney. Results : Out of total 254 subjects, there were 98 patients who met the initial criteria and were randomized into two groups, AFA and placebo group with each consisting of 49 subjects. Both groups were comparable in all important prognostic factors. The composite WOMAC Index scores in AFA group was significantly different than the placebo group at the end of the study (p <0.001), with each score of 8 (IQR,median 3-18) vs. 18 (IQR,median 8-32) respectively. There was no serious adverse events found throughout the study. Conclusion : Aphanizomenon Flos Aquae was able to show clinical improvement based on WOMAC scoring index and safe to use in the older adults with Knee OA.;Background: Aphanizomenon Flos Aquae is a species of blue-green algae which is commonly used as nutritional supplement in the world, including in Indonesia and is known to have many beneficial biological activities such as antiinflammatory, anti-oxidant and analgesics. Osteoarthritis (OA) knee is a problem that is quite common in the older people but until now there has not been pharmacologic modalities as a adjunctive therapy available which are suitable and safe. Aphanizomenon Flos Aquae may become a good alternative as an adjunctive therapy in older patients with knee OA. Objective : To determine the effect of AFA on the improvement of clinical outcome of Knee OA in older patients based on WOMAC index scores. Methods : A double-blind randomized clinical trial was conducted from November 2014 until May 2015 to older adult patients with Knee OA at the Geriatric and Rheumatology clinic in Hasan Sadikin General Hospital. The subjects were divided into groups, each group received capsules containing AFA 2 times 2 capsules (1.28 gr/day) and the other received placebo for 60 days. WOMAC Index scores were assessed at day 1 and day 60. The difference in assessment of WOMAC index scores of each group at the end of the study were analyzed by Mann-Whitney. Results : Out of total 254 subjects, there were 98 patients who met the initial criteria and were randomized into two groups, AFA and placebo group with each consisting of 49 subjects. Both groups were comparable in all important prognostic factors. The composite WOMAC Index scores in AFA group was significantly different than the placebo group at the end of the study (p <0.001), with each score of 8 (IQR,median 3-18) vs. 18 (IQR,median 8-32) respectively. There was no serious adverse events found throughout the study. Conclusion : Aphanizomenon Flos Aquae was able to show clinical improvement based on WOMAC scoring index and safe to use in the older adults with Knee OA.
2016
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Stefanus Mendes Kiik
Abstrak :
Falls are a serious consequence of declining physical function. Otago exercise is a strength and balance training program designed to prevent falls and enhance health status among the elderly. This study aimed to investigate the effect of a 12- week Otago exercise intended to reduce the risk of falls and health status among the elderly with chronic illness in the social elderly institution. This quasi-experimental study employed a pre- and post-test design using a control group. The study involved an intervention group (21 respondents) and a control group (21 respondents). The sample used in this study were elderly living in a social elderly institution. The sample was selected using simple random sampling. The data were analyzed using Mann–Whitney test, independent t-test, and Chi-square test. Otago exercise significantly reduced the respondents’ risk of falling and enhanced their health status. Significant differences were observed between the two groups in terms of the risk of fall (p= 0.041) and health status (p= 0.011). Otago exercise significantly improves the health status and reduces the risk of falling among elderly with chronic illness. The exercise can be recommended for older adults with chronic illness in social elderly institutions and communities.
Jakarta: Fakultas Ilmu Keperawatan Universitas Indonesia, 2020
610 UI-JKI 23:1 (2020)
Artikel Jurnal  Universitas Indonesia Library
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Yoga Kertapati
Abstrak :
ABSTRAK
Status fungsional adalah kemampuan individu untuk melakukan pemenuhan kebutuhan dan perawatan diri secara mandiri dalam aktivitas rutin sehari-hari. Status fungsional yang menurun berdampak pada penurunan kemandirian, sehingga lansia menjadi ketergantungan. Penelitian ini bertujuan untuk mengetahui pengaruh intervensi keperawatan spiritual dan latihan chair yoga selama 12 sesi latihan terhadap status fungsional dan kepuasan hidup lansia. Penelitian kuasi eksperimen dengan kelompok kontrol dengan sampel 42 lansia kelompok perlakuan dan 42 lansia kelompok kontrol. Teknik pengambilan sampel yang digunakan adalah simple random sampling. Hasil penelitian menunjukkan intervensi keperawatan spiritual dan latihan chair yoga berpengaruh signifikan meningkatkan status fungsional (p=0,000) dan kepuasan hidup (p=0,000). Hasil uji MANCOVA menunjukkan pengaruh intervensi keperawatan spiritual dan latihan chair yoga diperkuat oleh usia dan aktivitas fisik (p=0,000). Spiritual dan latihan chair yoga dapat meningkatkan status fungsional dan kepuasan hidup pada lansia secara signifikan. Intervensi keperawatan spiritual dan latihan chair yoga merupakan salah satu terapi komplementer sebagai upaya peningkatan status fungsional dan kepuasan hidup lansia yang dapat digunakan oleh perawat di masyarakat
ABSTRACT
Functional status is an individual's ability to perform self intervention and activities of daily routine. The impact of functional status decreased on independence, so that the older people to dependency. The aim of this study to determine the effect of spiritual nursing intervention and chair yoga exercises on functional status and life satisfaction of older adults. The research design was quasi experimental with 42 subjects as intervention groups and 42 subjects as control groups. The simple random sampling was used. The results showed that spiritual nursing intervention and chair yoga exercises significantly effect to improve functional status (p = 0.000) and life satisfaction (p = 0.000). MANCOVA analyze that spiritual nursing intervention and chair yoga exercise were significantly increased with controled by age and physical activity (p = 0.000). Spiritual and chair yoga exercise can improve functional status and life satisfaction among older adults significantly. Spiritual nursing intervention and chair yoga exercise is an one of the complementary therapy as preventive effort to improve the functional status and life satisfaction among older adults can used by nurse in the community.
2016
T45883
UI - Tesis Membership  Universitas Indonesia Library
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Noto Dwimartutie
Abstrak :
Prevalensi pre-frail tinggi pada usia lanjut dan kondisi tersebut dapat berubah menjadi frail. Kolekalsiferol diduga memiliki potensi untuk memperbaiki sindrom frailty pada usia lanjut. Penelitian ini bertujuan mengkaji pengaruh kolekalsiferol terhadap kekuatan genggam tangan, kecepatan berjalan serta reseptor vitamin D (vitamin D receptor/VDR), interleukin-6 (IL-6), dan insulin-like growth factor-1 (IGF-1) monosit pada usia lanjut dengan pre-frail. Uji klinis acak tersamar ganda dilakukan di Poliklinik Geriatri RSCM pada bulan April–Desember 2021. Sebanyak 120 subjek dirandomisasi menjadi kelompok yang mendapat kolekalsiferol 4.000 IU/hari (60 subjek) serta kelompok yang mendapat plasebo/hari (60 subjek). Seluruh subjek mendapat suplementasi kalsium laktat 500 mg /hari. Pengamatan dilakukan selama 12 minggu. Terdapat 57 subjek pada kelompok kolekalsiferol dan 56 subjek pada kelompok plasebo yang menjalani penelitian hingga selesai. Analisis intention to treat dilakukan untuk mengevaluasi luaran kekuatan genggam tangan dan kecepatan berjalan, sedangkan analisis per protokol untuk mengevaluasi VDR, IL-6 dan IGF-1 monosit. Pada akhir pengamatan, tidak terdapat perbedaan bermakna pada kekuatan genggam tangan (p = 0,228), kecepatan berjalan (p = 0,734), VDR monosit (p = 0,45), IL-6 monosit (p = 0,57) dan IGF-1 monosit (p = 0,72) antara kedua kelompok perlakuan. Tidak ada korelasi antara perubahan VDR, IL-6 dan IGF-1 monosit dengan kekuatan genggam tangan dan kecepatan berjalan. Terdapat peningkatan kadar 25(OH)D yang bermakna pada masing-masing kelompok perlakuan dan peningkatan bermakna pada kelompok kolekalsiferol dibandingkan plasebo. Pemberian kolekalsiferol 4.000 IU pada usia lanjut pre-frail 12 minggu meningkatkan kadar 25(OH)D secara bermakna, namun belum terbukti dapat memperbaiki kekuatan genggam tangan, kecepatan berjalan, meningkatkan VDR dan IGF-1 monosit serta menurunkan IL-6 monosit. Fungsi ginjal memiliki pengaruh terhadap efek kolekalsiferol pada IGF-1 monosit. Kolekalsiferol meningkatkan jumlah monosit dengan IGF-1+ pada eGFR > 90, namun tidak pada eGFR 30–59. ......Pre-frail prevalence is higher in the elderly. Frailty status is a dynamic condition. Pre-frail can fall into a frail condition. Cholecalciferol is regarded to have potential effect to improve frailty syndrome in the elderly. This study aimed to determine the effect of cholecalciferol on hand grip strength, walking speed, vitamin D receptors, IL-6, and IGF-1 monocyte in pre-frail elderly. A randomized double-blind clinical trial study at the RSCM Geriatric Polyclinic was conducted from April to December 2021. A total of 120 subjects were randomized into groups receiving 4000 IU cholecalciferol/day (60 subjects) and groups receiving placebo/day (60 subjects). All subjects received calcium lactate supplementation 500 mg/day. Observations were made for 12 weeks. There were 57 subjects in the cholecalciferol group and 56 subjects in the placebo group who completed the study. An intention to treat analysis was performed to evaluate the output of hand grip strength and walking speed, while a per protocol analysis was performed to evaluate monocyte VDR, IL-6 and IGF-1.There were no significant differences in hand grip strength (p = 0,228), walking speed (p = 0,734), VDR monocyte (p = 0,45), IL-6 monocyte (p = 0,57) and IGF-1 monocyte (p = 0,72) between treatment groups. There were no correlation between changes in the VDR, IL-6 and IGF-1 monocytes with changes in hand grip strength and walking speed. There was a significant increase in 25(OH)D levels in each group and a significant difference between groups. Supplementation of cholecalciferol 4.000 IU daily for 12 weeks increased serum 25(OH)D level significantly, however it did not improve hand grip strength and walking speed, and did not affect VDR, IL-6 and IGF-1 monocytes in pre-frail elderly. Kidney function had an influence on the effect of cholecalciferol on monocyte IGF-1. Cholecalciferol increased the number of monocytes with IGF-1+ at eGFR > 90, but not at eGFR 30–59.
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
D-pdf
UI - Disertasi Membership  Universitas Indonesia Library
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Miller, Carol A.
Abstrak :
"This book provides comprehensive, easy-to-understand coverage of the theory and practice of gerontological nursing, addressing both physiologic and psychosocial aspects of aging, as well as broader issues such as cultural competence and legal and ethical concerns." -- Publisher.
Philadelphia: Wolters Kluwer, 2015
618.97 MIL n
Buku Teks  Universitas Indonesia Library
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