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Ditemukan 25 dokumen yang sesuai dengan query
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Findra Mellya Normasiwi
Pemanfaatan ekstrak etanol rimpang temu mangga (curcuma mangga val.) terhadap kadar bilirubin total dan bilirubin direct serum darah tikus (rattus norvegicus l.) jantan galur sprague-dawley = The utilization of ethanol extract mango ginger (curcuma mangga val.) rhizomes to total bilirubin and direct bilirubin of the sprague-dawley pure strain male rats (rattus norvegicus l.) blood serum
"Telah dilakukan penelitian untuk mengetahui bahwa ekstrak etanol rimpang temu mangga Curcuma mangga Val. berpengaruh terhadap kadar bilirubin total dan bilirubin direct akibat kerusakan hati yang diinduksi oleh karbon tetraklorida CCl4 . Hewan uji yang digunakan dalam penelitian yaitu 24 ekor tikus Rattus norvegicus L. jantan galur Sprague-Dawley yang dibagi menjadi enam perlakuan KK1, KK2, KP1, KP2, KP3, dan KP4 dengan empat kali ulangan. Kelompok KK1 merupakan kelompok kontrol normal yang tidak diinjeksikan CCl4 dan dicekok CMC 0.5 , KK2 merupakan kelompok kontrol perlakuan yang diinjeksikan CCl4 sebanyak 1 ml/kgBB secara intraperitoneal dan dicekok CMC 0,5 . Kelompok KP1, KP2, KP3, dan KP4 merupakan kelompok perlakuan yang diinjeksikan CCl4 1 ml/kgBB dan diberikan ekstrak temu mangga dengan dosis berturut-turut 10 mg/kgBB, 20 mg/kgBB, 40 mg/kgBB, dan 80 mg/kgBB. Hasil uji non parametrik Kruskal-Wallis ? = 0,05 menunjukkan bahwa dosis 10 mg/kgBB, 20 mg/kgBB, 40 mg/kgBB, dan 80 mg/kgBB berpengaruh terhadap kadar bilirubin total dan bilirubin direct. Hasil uji perbandingan berganda Dunnett T3 ? = 0,05 menunjukkan bahwa dosis-dosis tersebut tidak berbeda bermakna dengan KK1. Dengan demikian dosis-dosis tersebut memiliki efek kuratif karena dapat menurunkan kadar bilirubin total dan direct sampai mendekati kadar normal.
This study was conducted in order to observe that the ethanol extract of mango ginger rhizome Curcuma mangga Val. affect the level of total bilirubin and direct bilirubin due to liver damage induced by tetrachloride carbon CCl4 . The test animals in the study were 24 male rats Rattus norvegicus L. of Sprague Dawley strain that was divided into six treatment KK1, KK2, KP1, KP2, KP3 and KP4 and repeated four times. The KK1 group is a normal control group that was not injected with CCl4 and 0.5 CMC fed, KK2 group is a treatment group that was intraperitoneally injected with CCl4 treatment in the amount of 1 ml kgBW and 0.5 CMC fed. KP1, KP2, KP3 and KP4 are treatment groups that got injected with CCl4 1 ml kgBB and were given mango ginger rhizome ethanol extract each with a dose of 10 mg kgBW, 20 mg kgBW, 40 mg kgBW, and 80 mg kgBW respectively by oral. The results of Kruskal Wallis non parametric test 0,05 shows that the dose of 10 mg kgBW, 20 mg kgBW, 40 mg kgBW, and 80 mg kgBW impacted on total bilirubin and direct bilirubin levels. Dunnet rsquo s T3 0,05 multiple comparison test result shows that the dosages had no significant differences with KK1 group. In conclusions, the dosages could be deemed as have curative effects since they successfully reduce the level of total bilirubin and direct bilirubin until it approached normal level."
Lengkap +
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2017
S68302
UI - Skripsi Membership  Universitas Indonesia Library
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Anjar Prianto
Uji toksisitas ekstrak teripang (Holothuroidea: Echinodermata) dari pulau pramuka, kepulauan seribu, jakarta dengan metode brine shrimp lethality test (BSLT)
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2010
S31639
UI - Skripsi Open  Universitas Indonesia Library
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Niken Ekatiwi
Pengaruh infusa daun keluwih artocarpus camansi blanco terhadap kualitas spermatozoa mencit mus musculus l jantan di epididimis = Effects of breadnut leaf s infusion artocarpus camansi blanco intake on quality of spermatozoa of male mice mus musculus l in epididymis
"[ ABSTRAK
Telah dilakukan penelitian untuk mengetahui pengaruh infusa daun keluwih
(Artocarpus camansi Blanco) terhadap pematangan spermatozoa mencit (Mus
musculus L.) jantan di epididimis. Sebanyak 24 ekor mencit jantan dibagi menjadi
4 kelompok, yaitu kelompok kontrol (KK) yang diberikan perlakuan berupa
akuades, kelompok perlakuan 1 (KP1), kelompok perlakuan 2 (KP2), dan
kelompok perlakuan 3 (KP3) yang diberikan infusa daun keluwih dengan dosis
berturt-turut yaitu 2,5; 5; dan 10 g/kg bb selama 8 hari. Hasil penelitian
menunjukkan adanya penurunan persentase motilitas spermatozoa pada kelompok
perlakuan dosis 2,5 g/kg bb dan peningkatan persentase motilitas serta
abnormalitas pada dosis 5 g/kg bb dan 10 g/kg bb. Hasil penelitian menunjukkan
adanya penurunan persentase viabilitas spermatozoa pada kelompok perlakuan
dosis 2,5 g/kg bb; 5 g/kg bb; dan 10 g/kg bb. Hasil tersebut menunjukkan bahwa
pemberian infusa daun keluwih (Artocarpus camansi Blanco) memiliki pengaruh
terhadap kualitas dan kuantitas spermatozoa mencit jantan
ABSTRACT The research has been done to determine the effect of Keluwih Leaf?s infusion
intake on maturation of spermatozoa of male mice in epididymis. Twenty-four
male mice were divided into 4 groups; consisting of control group which were
given akuades intake and treatment group which were given infusion with doses
2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an
decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase
of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of
spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw;
and 10 g/kg bw. The result indicated that keluwih leaf?s infusion intake gave an
impact on quality and quantity of male mice spermatozoa.;The research has been done to determine the effect of Keluwih Leaf?s infusion
intake on maturation of spermatozoa of male mice in epididymis. Twenty-four
male mice were divided into 4 groups; consisting of control group which were
given akuades intake and treatment group which were given infusion with doses
2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an
decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase
of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of
spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw;
and 10 g/kg bw. The result indicated that keluwih leaf?s infusion intake gave an
impact on quality and quantity of male mice spermatozoa.;The research has been done to determine the effect of Keluwih Leaf?s infusion
intake on maturation of spermatozoa of male mice in epididymis. Twenty-four
male mice were divided into 4 groups; consisting of control group which were
given akuades intake and treatment group which were given infusion with doses
2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an
decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase
of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of
spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw;
and 10 g/kg bw. The result indicated that keluwih leaf?s infusion intake gave an
impact on quality and quantity of male mice spermatozoa.;The research has been done to determine the effect of Keluwih Leaf?s infusion
intake on maturation of spermatozoa of male mice in epididymis. Twenty-four
male mice were divided into 4 groups; consisting of control group which were
given akuades intake and treatment group which were given infusion with doses
2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an
decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase
of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of
spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw;
and 10 g/kg bw. The result indicated that keluwih leaf?s infusion intake gave an
impact on quality and quantity of male mice spermatozoa., The research has been done to determine the effect of Keluwih Leaf’s infusion
intake on maturation of spermatozoa of male mice in epididymis. Twenty-four
male mice were divided into 4 groups; consisting of control group which were
given akuades intake and treatment group which were given infusion with doses
2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an
decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase
of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of
spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw;
and 10 g/kg bw. The result indicated that keluwih leaf’s infusion intake gave an
impact on quality and quantity of male mice spermatozoa.]"
Lengkap +
Universitas Indonesia, 2016
S62726
UI - Skripsi Membership  Universitas Indonesia Library
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Hasna Nurul Fitri
Pengaruh sari buah jeruk Siam (citrus nobilis lour) dalam pengencer terhadap kualitas spermatozoa domba Garut (ovis aries l.) pascakriopreservasi = The effect of siam orange juice (citrus nobilis lour) in extender on garut ram (ovis aries l.) spermatozoa quality postcryopreservation
"Telah dilakukan penelitian untuk mengetahui pengaruh sari buah jeruk siam Citrus nobilis Lour. dalam pengencer tris kuning telur TKT terhadap kualitas spermatozoa domba garut Ovis aries L. 24 jam pascakriopreservasi. Semen ditampung dari lima pejantan domba garut satu kali dalam satu minggu menggunakan vagina buatan. Segera setelah dievaluasi, semen diencerkan dengan pengencer tris kuning telur yang mengandung sari buah jeruk 0 KK, 5 KP 1, 10 KP 2, 15 KP 3, dan 20 KP 4. Semen dikemas dalam straw 0,25 ml dengan konsentrasi akhir 50x106 spermatozoa/ml. Semen diekuilibrasi pada suhu 5oC selama dua jam kemudian dibekukan dan disimpan dalam tabung N2 cair. Semen dievaluasi terhadap parameter motilitas, viabilitas, integritas membran, integritas akrosom, dan abnormalitas. Hasil uji ANAVA satu arah menunjukkan terdapat perbedaan nyata antar kelompok perlakuan terhadap persentase motilitas, viabilitas, dan integritas membran p < 0,05. Hasil uji lanjut Duncan menunjukkan bahwa KP 2 memiliki perbedaan nyata terhadap semua kelompok perlakuan. Berdasarkan hasil tersebut, penambahan sari buah jeruk pada konsentrasi 10 KP 2 merupakan konsentrasi terbaik yang mampu memperkecil penurunan kualitas spermatozoa domba garut pascakriopreservasi berdasarkan persentase motilitas 58,68 0,68, viabilitas 59,73 6,47, dan integritas membran 54,87 5,58.
The research aimed to find out the effect of siam orange juice in extender on garut ram spermatozoa quality 24 hours postcryopreseration. Semen was collected from five rams once a week using artificial vagina. Semen sample was diluted in tris egg yolk based extender containing 0 KK, 5 KP 1, 10 KP 2, 15 KP 3 and 20 KP 4 siam orange juice. Semen was packed in 0.25 ml straw with a final concentration of 50x106 spermatozoa ml. Sperm was equilibrated at 5 C for two hours then frozen and stored in a liquid nitrogen N2 tube. Sperm parameters including motility, viability, membrane integrity, acrosome integrity, and abnormality were assessed. One way ANAVA test results showed significant differences between treatment groups on the percentage of motility, viability, and membrane integrity."
Lengkap +
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2017
S68124
UI - Skripsi Membership  Universitas Indonesia Library
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Arsya Ramadina Semudi
Perilaku Sosial dan Reproduksi Harimau Sumatra (Panthera tigris sumatrae) di Taman Margasatwa Ragunan, Jakarta Selatan = Social and Reproductive Behaviors of Male and Female Sumatran Tiger (Panthera tigris sumatrae) in Ragunan Zoo, South Jakarta
"Harimau sumatra merupakan salah satu spesies endemik Indonesia yang keberadaannya terancam punah (critically endangered) menurut IUCN sehingga diperlukan upaya konservasi. Konservasi harimau sumatra dilakukan Taman Margasatwa Ragunan (TMR) beserta IUCN melalui program GSMP (Global Species Management Plan) yang dilakukan secara collaborative breeding. Collaborative breeding dilakukan dengan memasangkan betina asal TMR dengan jantan hasil pertukaran dengan Medan Zoo untuk mencegah inbreeding. Pemasangan harimau harus melalui proses introduksi dan interaksi keduanya perlu diamati. Oleh karena itu, penelitian dilakukan terhadap pasangan harimau sumatra untuk menganalisis perilaku sosial yang terjadi antara harimau sumatra jantan dan betina yang mungkin mengarah ke perilaku reproduksi. Metode scan sampling dan ad libitum digunakan dalam penelitian selama tiga jam perhari dengan total pengulangan sebanyak 23 kali dari Januari hingga Maret 2024. Pengambilan data dilakukan dengan mengamati perilaku sosial dan reproduksi harimau sumatra jantan dan betina di kandang dalam Zona Harimau 1 Taman Margasatwa Ragunan. Hasil dari penelitian ini didominasi oleh perilaku sosial berupa perilaku saling mendekati (♀ 26,29%; ♂ 21,58%). Perilaku chuffing, head rubbing dan sniffing lebih sering dilakukan kedua harimau sumatra dibandingkan dengan perilaku growl dan aggression. Jantan dan betina juga melakukan perilaku reproduksi, yaitu flehmen, sedangkan mating call dan sniffing genitalia hanya dilakukan oleh jantan. Penelitian ini menunjukkan adanya perilaku sosial harimau sumatra yang mengarah pada perilaku reproduksi, yaitu perilaku chuffing, head rubbing, body rubbing, flehmen dan sniffing genitalia.
The sumatran tiger is one of Indonesia's endemic species that is critically endangered according to the IUCN so that conservation efforts are needed. Sumatran tiger conservation is carried out by Ragunan Zoo (TMR) and IUCN through the GSMP (Global Species Management Plan) by doing collaborative breeding. Collaborative breeding is done by pairing female from TMR with male from Medan Zoo to prevent inbreeding. The pairing of tigers must go through an introduction process and their interactions need to be observed. Therefore, research was conducted on pairs of sumatran tigers to analyze the social behaviors that occurs between male and female sumatran tigers that may lead to reproductive behavior. Scan sampling and ad libitum methods were used in the study for three hours per day with a total of 23 repetitions from January to March 2024. Data were collected by observing the social and reproductive behavior of male and female sumatran tigers in sleeping cages, Tiger Zone 1 of Ragunan Zoo. The results of this study were dominated by social behavior in the form of approaching behavior (♀ 26,29%; ♂ 21,58%). Chuffing, head rubbing and sniffing behaviors were more often performed by both sumatran tigers compared to growl and aggression behaviors. Male and female sumatran tigers also perform reproductive behaviors, such as flehmen, while mating calls and genitalia sniffing are only done by male. This study shows the existence of social behavior of sumatran tigers that lead to reproductive behavior, such as chuffing, head rubbing, body rubbing, flehmen and sniffing genitalia."
Lengkap +
Depok: Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Indonesia, 2024
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Elfa Thufeil Rahmi
Pola aktivitas harian sepasang simpanse (Pan troglodytes Blumenbach,1799) di pusat primata schmutzer
2010
S31591
UI - Skripsi Open  Universitas Indonesia Library
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Rahayu Purwasih
Pengaruh pemberian Biomassa Rhodotorulla minuta UICC Y-227 terhadap konsentrasi kolesterol total, LDL, dan HDL plasma darah tikus putih (Rattus norvegicus L.) Galur Sprague Dawles
2010
S31636
UI - Skripsi Open  Universitas Indonesia Library
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Berta Putri
Potensi teripang pasir (holothuria scabra jaeger 1833) dan kerang dara (anadara granosa linn. 1758) sebagai biofilter limbah budidaya intensif udang putih (litopenaeus vannamel boone 1931)
2007
T39502
UI - Tesis Membership  Universitas Indonesia Library
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Tarore, Jennifer Jeromiah
Penentuan standar data morfometri dan berat badan macaca fascicularis berdasarkan kelompok umur dan jenis kelamin di penangkaran PT Indo Biomedical, Jonggol = Determenination of morphometric and weight's standard data of Macaca fascularis based on age group and sez in PT Indo Biomedical's captive, Jonggol
"Macaca fascicularis merupakan primata yang sering digunakan sebagai hewan uji dalam penelitian, sehingga kondisi fisiologisnya harus diperhatikan karena berpengaruh terhadap hasil penelitian, terutama penelitian tentang pertumbuhan. Standarisasi berat badan dan morfometri membantu penelitian tentang pertumbuhan, namun standarisasi tersebut memerlukan sampel yang banyak agar hasil tidak bias. Penangkaran milik PT Indo Biomedical, Jonggol memiliki banyak M. fascicularis dan belum memiliki standar data morfometri dan berat badan, sehingga dapat dilakukan penelitian penentuan standar data berat badan dan morfometri di penangkaran tersebut.
Tujuan penelitian ini untuk mendapatkan standar data karakter morfometri dan berat badan M. fascicularis. Jumlah hewan yang digunakan sebanyak 698 ekor dengan rincian 175 ekor bayi, 248 ekor infan, 209 ekor juvenil, dan 66 ekor pra-dewasa. Parameter yang diukur yakni berat badan, tinggi duduk, panjang ekor, panjang lengan atas, panjang lengan bawah, panjang paha, dan panjang betis.
Hasil pengolahan data dengan metode Analisis Komponen Utama (AKU) menunjukkan bahwa individu bayi dan infan M. fascicularis memiliki parameter standar terbaik lengan bawah, sedangkan individu juvenil dan pra-dewasa memiliki parameter standar terbaik lengan atas. Hasil uji-T terhadap rerata data morfometri dan berat badan M. fascicularis menunjukkan bahwa terdapat perbedaan morfologi yang nyata antara individu jantan dan betina M. fascicularis pada kelompok umur pra-dewasa.
Macaca fascicularis is a kind of primate that often used as animal model in research, therefore, physiological condition must be considered because the influence of the result of research. Standardization of weight and morphometry assist research on growth, but these standards require that many samples that the results are not biased. Captive owned by PT Indo Biomedical, Jonggol has a lot of M. fascicularis and did not yet had data standard morphometry and weight, therefore it can be done research determination standardization of weight and morphometry in there.
The purpose of this study was to get a M. fascicularis basic standard characteristics of morphometrics and body weight. The number of animals observed were 698 consisting of 175 babies, 248 infants, 209 juveniles, and 66 sub-adults. The parameters were included body weight, body length, tail length, upper arm length, forearm length, thigh length, and calf length.
The Principal Component Analysis (PCA) showed that the individu of M. fascicularis of the babies and the infants age-group had the best forearm length parameter measurement standard, while the juveniles and the sub-adults age-group of M. fascicularis had the best upper arm length as their best parameter measurement standard. The result of processing data used T-test of mean of morphometrics and body weight indicated there was real significance of morphological differences between male and female individuals of M. fascicularis sub-adult age groups."
Lengkap +
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2011
S1605
UI - Skripsi Open  Universitas Indonesia Library
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Ovy Aulia
Uji teratogenik ekstrak etanol daun salam (syzygium polyanthum wight.) terhadap morfologi fetus mencit mus musculus l. galur ddy = Teratogenic test of bay leaf (syzygium polyanthum wight) ethanol extract on morphology of fetal mice mus musculus l strain ddy
"Telah dilakukan uji teratogenik ekstrak etanol daun salam (Syzygium polyanthum Wight.) yang bertujuan untuk mengetahui pengaruh pemberian ekstrak tersebut terhadap morfologi fetus mencit (Mus musculus L.) galur DDY. Tiga puluh ekor mencit betina bunting dibagi menjadi 5 kelompok yang terdiri dari kelompok kontrol dan kelompok dosis 0,5; 5; 50 dan 500 mg/kg bb. Bahan uji diberikan secara oral sejak hari ke-6 hingga ke-15 kebuntingan. Pembedahan dilakukan pada hari ke-18 kebuntingan.
Hasil penelitian menunjukkan pengaruh pemberian ekstrak etanol daun S. polyanthum pada dosis 0,5 mg/kg bb tidak menimbulkan resorpsi dan malformasi eksternal. Pada dosis 5 mg/kg bb ditemukan resorpsi (6,15%) dan fetus kelopak mata terbuka (1,63%). Pada dosis 50 dan 500 mg/kg bb ditemukan resorpsi (7,69%; 9,34%) dan fetus hemoragi (1,63%; 1,47%).
Meski demikian, secara statistik (P > 0,05) pemberian ekstrak etanol daun S. polyanthum pada dosis 0,5; 5; 50 dan 500 mg/kg bb selama periode organogenesis tidak memberikan pengaruh yang signifikan terhadap perkembangan morfologi fetus mencit.
This research was conducted to observe the teratogenic potential of S. polyanthum ethanol extract on morphology of fetal mice strain DDY. Thirty pregnant female mice were divided into 5 groups, consisting of normal group and treatment groups with dose 0.5; 5; 50 and 500 mg/bw. The extract was given orally from 6th to 15th day of gestation.
The results showed that the effect of S. polyanthum ethanol extract at a dose of 0.5 mg/bw did not cause resorption and external malformation. At a dose of 5 mg/bw extract given, there were resorption (6.15%) and fetal eyelids open (1.63%). Resorption (7.69%; 9.34%) and fetal hemorrhage (1.63%; 1.47%) were found in mice given doses of 50 and 500 mg/bw.
However, statistic test (P> 0.05) showed that the treatment of S. polyanthum ethanol extract at doses of 0.5; 5; 50 and 500 mg/bw during the period of organogenesis did not have a significant influence on morphology of fetal mice strain DDY."
Lengkap +
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2016
S64835
UI - Skripsi Membership  Universitas Indonesia Library
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