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"Latar Belakang dan Tujuan: Rigid Cystoscopy merupakan pemeriksaan menggunakan cystoscope yang rigid untuk mengetahui kelainan pada kandung kemih. Kelainan yang dapat dinilai dari pemeriksaan ini adalah tumor, batu, hematuria dan inflamasi kandung kemih. Dapat juga digunakan untuk pemasangan kateter ureter dan pengangkatan double J. Dengan hanya menggunakan anestetik lokal xylocaine jelly 2% saja pada prosedur ini sebagian penderita masih belum dapat mentoleransi nyeri. Sementara elektroakupunktur (EA) telah terbukti dapat mengurangi nyeri pada beberapa tindakan/operasi. Penelitian ini bertujuan untuk mengetahui efek EA dikombinasi dengan xylocaine jelly 2% terhadap nyeri pada prosedur rigid cystoscopy pasien laki-laki. Metode: Uji klinis dilakukan sebelum dan setelah intervensi. Tujuh belas pasien laki-laki yang akan menjalani prosedur rigid cystoscopy dan memenuhi kriteria insklusi dilibatkan dalam studi ini. Perlakuan menggunakan EA tubuh dan telinga selama 20 menit, kemudian ditambahkan xylocaine jelly 2% 10 ml selama 10 menit sebelum prosedur dimulai. Penilaian dilakukan dengan NAS terutama pada sebelum, selama dan setelah prosedur selesai. Hasil: Rerata NAS sebelum prosedur 1,06±1,09; selama prosedur 2,0±1,17; dan setelah prosedur 0,76±1,20. Terdapat perbedaan bermakna antara NAS sebelum vs selama prosedur dan NAS selama vs setelah prosedur, p<0,01; tidak ada perbedaan bermakna antara NAS sebelum vs setelah prosedur, p>0,05. Tidak didapatkan kriteria buruk (gagal) atau nilai NAS >4, serta efek samping pada sebelum, selama dan setelah prosedur. Kesimpulan: EA tubuh dan telinga kombinasi dengan xylocaine jelly 2% mempunyai efek mengurangi nyeri yang dapat ditoleransi penderita pada prosedur rigid cystoscopy laki-laki.

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Background and Objective: Rigid cystoscopy is an examination using a rigid cystoscope to determine bladder abnormalities. Abnormalities which can be it from this examination were tumor, stones, hematuria and bladder inflamation. It can also be used for the installation and removal of the ureteral double J catheter. Some patients still can not tolerate the pain if this procedure only used local anesthetic xylocaine jelly 2%. While electroacupuncture (EA) has been proven to reduce pain in some action/operations. This study aim to determine effect of EA combination with xylocaine jelly 2% on pain in rigid cystoscopy procedure in men patients.

Methods: Clinical trial performed before and after intervention. Seventeen male patients that will undergo rigid cystoscopy procedure and fulfill inclusion criteria were included in this study. The treatment using body and ears EA for 20 minutes, then added xylocaine jelly 2% 10 ml for 10 minutes before procedure begin. Assesment carried with NAS espesially before, during and after procedure.

Results: The means NAS before procedure was 1,06±1,09; during procedure 2,0±1,17; and after procedure 0,76±1,20. There are significant differences between NAS before vs during procedure and during vs after procedure, p<0,01; there is no significant difference between NAS before vs after procedure, p>0,05. Not bad criterion (fail) or the value of NAS >4 and side effect before, during and after the procedure.

Conclusions: Body and ears EA combination with xylocaine jelly 2% have effect reducing pain that can be tolerated by the patients on the rigid cystoscopy procedur in men."

"ABSTRAKLatar belakang: Migren adalah serangan nyeri kepala primer, bersifat spesifik, paroksismal, dengan atau tanpa aura, dengan manifestasi subjektif baik sebelum maupun sesudah serangan, merupakan nyeri kepala tipe kronik dengan gejala rekurensi, menyerang usia produktif dan dapat menyebabkan penurunan produktivitas kerja hingga 80%, sehingga akan mempengaruhi kualitas hidup dan kehidupan perekonomian dan pendidikan secara global yang mengarah kepada kerugian bagi penderita migren dan institusi tempat penderita migren bersekolah ,bekerja serta dalam kehidupan keluarga penderita. Dengan tingginya angka prevalensi dan disabilitas pada penderita migren, dilain pihak sampai saat ini pengobatan yang tepat terhadap migren belum didapatkan secara maksimal maka diperlukan pendalaman dalam pengobatan maupun pencegahan migren sangat dibutuhkan., dan sampai saat ini belum didapatkan obat yang pasti, baik terhadap pencegahan dan pengobatan, sehingga perlu dikembangkan terapi yang dapat memberikan pertolongan yang lebih akurat pada penderita migrenTujuan penelitian ini adalah menilai keberhasilan dalam penatalaksanaan migren dalam mengurangi frekuensi serangan, mengurangi intensitas serangan dan mengurangi durasi serangan dari minggu ke-0,ke-4 hingga ke-8. Metode: Uji klinis acak tersamar tunggal dengan kontrol dilakukan terhadap 34 subjek dengan migren yang dialokasikan secara acak kedalam kelompok manual akupunktur (n=17), serta kelompok medikamentosa (n=17). Penilaian menilai frekuensi, durasi dan intensitas serangan migren yang dinilai pada saat sebelum perlakuan, minggu ke-4 dan minggu ke-8 dari baseline. Hasil: Hasil penelitian menunjukkan terdapat perbedaan bermakna antara kedua kelompok pada rerata jumlah frekuensi (p=0,040), durasi (p=0,012) dan intensitas (p=0,003) serangan migren pada minggu ke-4 dibandingkan dengan medikamentosa. Serata terdapat perbedaan yang bermakna antara kedua kelompok pada rerata jumlah jumlah frekuensi (p=0,029), durasi (p=0,001) dan intensitas (p<0,001) serangan migren pada minggu ke-8. Kesimpulan: Intervensi akupunktur manual dapat menurunkan frekuensi, durasi dan intensitas serangan migren lebih baik dibandingkan dengan preventif farmakologi asam valproat pada minggu ke-4 dan minggu ke-8.

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ABSTRACTBackground: Migraine is a primary headache attack, specific, paroxysmal, with or without aura, with subjective manifestations both before and after the attack, a chronic type of headache with symptoms of recurrence, attacks at productive age and can cause a decrease in work productivity up to 80%, so that it will affect the quality of life, economic life and education globally which leads to losses for migraine sufferers and institutions where migraine sufferers attend school, work and in the lives of sufferers families. With the high prevalence and disability rates for migraine sufferers, on the other hand, the right treatment for migraine has not yet been obtained to the maximum, it is necessary to deepen the treatment and prevention of migraine is needed, and until now there has been no definitive cure, both for prevention and treatment, so it is necessary to develop therapies that can provide more accurate relief for migraine sufferers. The purpose of this study is to assess the success in managing migraine in reducing the frequency of attacks, reducing the intensity of attacks and reducing the duration of attacks from weeks 0, 4 to 8. Methods: A randomized controlled trial with control was conducted on 34 subjects with migraine who were randomly allocated into the manual group of acupuncture (n = 17), as well as the medicine group (n = 17). The assessment of frequency, duration and intensity of migraine attacks assessed at the time before treatment, at the fourth and eight week from baseline. Results: The results showed there were significant differences between the two groups in the mean number of frequencies (p = 0.040), duration (p = 0.012) and intensity (p = 0.003) of migraine attacks at the fourth week. There were significant differences between the two groups in the average number of frequencies (p= 0.029), duration (p=0.001) and intensity (p<0.001) of migraine attacks at the eight week. Conclusion: Manual acupuncture interventions can reduce the frequency, duration and intensity of migraine attacks better than the use of valproic acid in the fourth and eight week."

"ABSTRAKLatar belakang:Migren adalah serangan nyeri kepala primer, bersifat spesifik,paroksismal, dengan atau tanpa aura, dengan manifestasi subjektif baik sebelummaupun sesudah serangan, merupakan nyeri kepala tipe kronik dengan gejala rekurensi,menyerang usia produktif dan dapat menyebabkan penurunan produktivitas kerja hingga80%, sehingga akan mempengaruhi kualitas hidup dan kehidupan perekonomian danpendidikan secara global yang mengarah kepada kerugian bagi penderita migren daninstitusi tempat penderita migren bersekolah ,bekerja serta dalam kehidupan keluargapenderita. Dengan tingginya angka prevalensi dan disabilitas pada penderita migren,dilain pihak sampai saat ini pengobatan yang tepat terhadap migren belum didapatkansecara maksimal maka diperlukan pendalaman dalam pengobatan maupun pencegahanmigren sangat dibutuhkan., dan sampai saat ini belum didapatkan obat yang pasti, baikterhadap pencegahan dan pengobatan, sehingga perlu dikembangkan terapi yang dapatmemberikan pertolongan yang lebih akurat pada penderita migrenTujuan penelitian ini adalah menilai keberhasilan dalam penatalaksanaan migren dalammengurangi frekuensi serangan, mengurangi intensitas serangan dan mengurangi durasiserangan dari minggu ke-0,ke-4 hingga ke-8. Metode: Uji klinis acak tersamar tunggaldengan kontrol dilakukan terhadap 34 subjek dengan migren yang dialokasikan secaraacak kedalam kelompok manual akupunktur (n=17), serta kelompok medikamentosa(n=17). Penilaian menilai frekuensi, durasi dan intensitas serangan migren yang dinilaipada saat sebelum perlakuan, minggu ke-4 dan minggu ke-8 dari baseline. Hasil: Hasilpenelitian menunjukkan terdapat perbedaan bermakna antara kedua kelompok padarerata jumlah frekuensi (p=0,040), durasi (p=0,012) dan intensitas (p=0,003) seranganmigren pada minggu ke-4 dibandingkan dengan medikamentosa. Serata terdapatperbedaan yang bermakna antara kedua kelompok pada rerata jumlah jumlah frekuensi(p=0,029), durasi (p=0,001) dan intensitas (p<0,001) serangan migren pada minggu ke-8. Kesimpulan: Intervensi akupunktur manual dapat menurunkan frekuensi, durasi danintensitas serangan migren lebih baik dibandingkan dengan preventif farmakologi asamvalproat pada minggu ke-4 dan minggu ke-8.

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ABSTARCTMigraine is a primary headache attack, specific, paroxysmal, with or without aura, with subjective manifestations both before and after the attack, a chronictype of headache with symptoms of recurrence, attacks at productive age and can cause a decrease in work productivity up to 80%, so that it will affect the quality of life, economic life and education globally which leads to losses for migraine sufferers andinstitutions where migraine sufferers attend school, work and in the lives of sufferersfamilies. With the high prevalence and disability rates for migraine sufferers, on theother hand, the right treatment for migraine has not yet been obtained to the maximum,it is necessary to deepen the treatment and prevention of migraine is needed, and untilnow there has been no definitive cure, both for prevention and treatment, so it isnecessary to develop therapies that can provide more accurate relief for migrainesufferers. The purpose of this study is to assess the success in managing migraine inreducing the frequency of attacks, reducing the intensity of attacks and reducing theduration of attacks from weeks 0, 4 to 8. Methods: A randomized controlled trial withcontrol was conducted on 34 subjects with migraine who were randomly allocated intothe manual group of acupuncture (n = 17), as well as the medicine group (n = 17). Theassessment of frequency, duration and intensity of migraine attacks assessed at the timebefore treatment, at the fourth and eight week from baseline. Results: The resultsshowed there were significant differences between the two groups in the mean numberof frequencies (p = 0.040), duration (p = 0.012) and intensity (p = 0.003) of migraineattacks at the fourth week. There were significant differences between the two groups inthe average number of frequencies (p= 0.029), duration (p=0.001) and intensity(p<0.001) of migraine attacks at the eight week. Conclusion: Manual acupunctureinterventions can reduce the frequency, duration and intensity of migraine attacksbetter than the use of valproic acid in the fourth and eight week."

"Penyakit Paru Obstruktif Kronik (PPOK) kini telah menjadi penyebab kematian terbanyak keempat di dunia. Masih tingginya angka mortalitas pada tatalaksana PPOK mengharuskan pengembangan modalitas terapi yang terus-menerus. Penelitian ini bertujuan untuk mengetahui pengaruh terapi kombinasi akupunktur tanam benang dan medikamentosa terhadap indeks BODE pasien PPOK. Uji klinis acak tersamar ganda dengan pembanding dilakukan terhadap 48 pasien yang dialokasikan ke dalam kelompok kasus (kombinasi akupunktur tanam benang dan medikamentosa) atau kelompok kontrol (kelompok akupunktur sham dan medikamentosa). Akupunktur tanam benang dilakukan pada titik BL13 Feishu, BL43 Gaohuangshu, BL20 Pishu, BL23 Shenshu dan ST40 Fenglong sebanyak 2 kali dengan interval 15 hari. Indeks BODE sebagai keluaran primer dinilai pada hari ke-1 dan hari ke-30. Hasil penelitian menunjukkan perbedaan yang bermakna secara statistik maupun klinis antar kedua kelompok. Rerata penurunan indeks BODE 1,83 lebih rendah pada kelompok kasus dibandingkan dengan kelompok kontrol (p =0,000). Disimpulkan bahwa terapi kombinasi akupunktur tanam benang dan medikamentosa lebih efektif menurunkan Indeks BODE dibandingkan dengan medikamentosa saja.

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Chronic Obstructive Pulmonary Disease (COPD) is now becoming the fourth leading cause of death in the world. Since high level of mortality following COPD medication, continous research to improve treatment modalities keeps on progressing. This study aimed to establish the effect of acupoint-catgut embedment combined with medical treatment on BODE index of COPD patient. A double blind randomized controlled trial has been conducted on 48 patient allocated into acupoint-catgut embedment with medication group (case group) or sham acupuncture with medication group (control group). Acupoint-catgut embedment was done on BL13 Feishu, BL43 Gaohuangshu, BL20 Pishu, BL23 Shenshu and ST40 Fenglong, 2 times with interval 15 days. BODE index as primary outcome was assessed on day-1 and day-30. The result shown statistically and clinically important difference between groups. BODE index was reduced 1,83 point lower in case group (p = 0,000). By that result, acupoint-catgut embedment combined with medical treatment is concluded more effective than medical treatment solely in reducing BODE index."

"ABSTRAK Gastroesophageal reflux disease (GERD) merupakan suatu kondisi patologis yang disebabkan oleh refluks kandungan lambung ke dalam esofagus. GERD memiliki dampak yang besar terhadap penderitanya baik secara fisik, psikologik, sosial maupun ekonomi. Penurunan kualitas hidup dan produktifitas kerja sering ditemukan pada penderita GERD. Berbagai terapi farmakologis telah dikembangkan, namun belum memberikan hasil yang optimal. Hal tersebut mendorong pengembangan modalitas terapi lain, salah satunya akupunktur tanam benang. Penelitian ini bertujuan untuk mengetahui efektifitas terapi kombinasi akupunktur tanam benang dan medikamentosa terhadap gejala dan kualitas hidup penderita GERD. Uji klinis acak tersamar ganda dengan pembanding dilakukan terhadap 52 penderita GERD yang dialokasikan secara acak ke dalam kelompok kombinasi akupunktur tanam benang dan medikamentosa (kelompok perlakuan) atau kelompok akupunktur sham dan medikamentosa (kelompok kontrol). Akupunktur tanam benang dilakukan pada titik CV12 Zhongwan, ST36 Zusanli dan BL21 Weishu sebanyak 2 kali dengan interval 15 hari. Skor GERDQ, RQS dan SF-36 digunakan untuk mengukur keluaran terapi. Hasil penelitian menunjukkan bahwa penurunan skor GERDQ pada kelompok perlakan lebih besar dari kelompok kontrol (p<0,001) dan peningkatan skor RQS serta peningkatan skor seluruh komponen SF-36 pada kelompok perlakuan lebih besar dibanding kelompok kontrol (p<0,001). Kesimpulan penelitian adalah terapi kombinasi akupunktur tanam benang dan medikamentosa lebih efektif dalam mengurangi gejala dan meningkatkan kualitas hidup penderita GERD dibandingkan dengan terapi medikamentosa saja ABSTRACT Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients.;Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients.;Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients.;Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients.;Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients."

"Obesitas merupakan penurun kualitas hidup, menggangu emosi dan keuangan individu, keluarga dan sosial mereka. Subjek juga akan mengalami peninhgkatan resiko yang berkaitan dengan kondisi seperti penyakit jantung koroner, dibetes tipe II, stroke, osteoartritis dan kanker. Indeks massa tubuh, gambaran lemak dan skor nafsu makan merupakan indeks yang sering digunakan dalam mengontrol obesitas. Modifikasi diet, intervensi gaya hidup, intervensi farmakologi dan pembedahan merupakan pilihan terapi obesitas, namun pilihan terapi yang aman dan efektif sangat diperlukan. Terapi akupunktur secara signifikan dapat menurunkan indeks massa tubuh dengan mereduksi jaringan lemak viseral abdomen, yang mengarah ke regulasi metabolisme lemak. Laserpunktur merupakan intervensi yang menstimulasi titik akupunktur tradisional mengguankan terapi laser. Dibandingkan dengan akupunktur manual, laserpunktur memiliki berbagai kelebihan seperti aplikasi yang mudah, dosis yang dapat tepat diukur , tidak nyeri dan tidak invasif. Penelitian ini menilai efek kombinasi laserpunktur dan intervensi diet terhadap kadar high density lipoprotein, trigliserida, indeks massa tubuh dan skor nafsu makan pasien obesitas. Tiga puluh delapan pasien dibagi secara acak menjadi dua kelompok, kelompok laserpunktur dan intervensi diet (n = 19) dan kelompok laserpunktur sham dan intervensi diet (n = 19). Kedua kelompok menerima intervensi diet dan sesi laserpunktur yang sama, 3 kali/minggu selama 4 minggu. Pengukuran kadar high density lipoprotein, trigliserida, indeks massa tubuh dan skor nafsu makan dilakukan sebelum dan sesudah sesi terapi. Hasil menunjukkan terdapat perbedaan bermakna pada indeks massa tubuh (p=0,000, CI 95%) dan skor nafsu makan (p=0,000, CI 95%) antara kelompok laserpunktur dan intervensi diet dengan kelompok laserpunktur sham dan intervensi diet. Kelompok laserpunktur dan intervensi diet juga menunjukkan adanya perbedaan bermakna pada kadar high density lipoprotein (p=0,000, CI 95%) dan trigliserida (p=0,000, CI 95%) sebelum dan sesudah sesi terapi. Penemuan ini menunjukkan bahwa kombinasi laserpunktur dan intervensi diet memberikan efek yang baik terhadap kadar high density lipoprotein, trigliserida, indeks massa tubuh dan skor nafsu makan pada pasien obesitas.

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Obesity is a detriment to quality of life, places emotion and financial burden on the individual, their families, and society. Subjects also have an increased risk of associated conditions, such as coronary heart disease, type II diabetes, stroke, osteoarthritis, and cancers. Body mass index, lipid profile, and appetite score are the indices commonly used for controlling obesity. Dietary modification, lifestyle interventions, pharmacological interventions, and surgery are treatment choices for obesity, but more safe and effective treatment options are needed.

Acupuncture therapy significantly reduces body mass index by reducing the abdominal visceral adipose tissue content, which lead to regulating lipid metabolism. Laserpuncture is an intervention that stimulates traditional acupoints using laser therapy. Compared to manual acupuncture, laserpuncture has multiple advantages, including ease of application, dose measurement precision, painlessness, and noninvasiveness.

This study investigates the effect of combined laserpuncture and diet intervention on high density lipoprotein level, trigliceride, body mass index, and appetite score in obese patient. Thirty eight patients were divided randomly into two groups, laserpuncture with diet intervention group (n = 19) and sham laserpuncture with diet intervention group (n =19). Both group received the same diet intervention and sessions of laserpuncture, 3 times/week for 4 weeks. Body mass index measurement, high density lipoprotein levels, trigliceride levels, and appetite score were assessed before and after the treatment course.

The result shows there is a statiscally significant difference on body mass index (p=0,000, CI 95%) and  appetite score (p=0,000, CI 95%) between the laserpuncture with diet intervention group and sham laserpuncture with diet intervention group. The laserpuncture with diet intervention group also shows a statiscally significant difference on high density lipoprotein level (p=0,000, CI 95%) and trigliceride level (p=0,000, CI 95%) before and after treatment course. These findings suggest that combined laserpuncture and diet intervention has good effect on high density lipoprotein level, trigliceride, body mass index, and appetite score in obese patient."

"Sindrom ovarium polikistik (SOPK) merupakan suatu kondisi umum endokrinopati yang ditandai dengan adanya oligoovulasi atau anovulasi, produksi androgen berlebih, dan adanya kista ovarium kecil multipel yang diidentifikasi secara sonografis (kriteria Rotterdam, 2004). SOPK ditemukan pada 10% populasi wanita usia reproduksi dan berhubungan erat dengan disfungsi ovulasi sehingga menurunkan angka fertilitas. Tujuan penelitian ini adalah untuk mengetahui pengaruh terapi kombinasi elektroakupunktur dan medikamentosa terhadap SOPK. Uji klinis acak tersamar ganda dengan kontrol dilakukan terhadap 44 subjek dengan SOPK yang dialokasikan secara acak ke dalam kelompok elektroakupunktur sejati dan medikamentosa (n=22), serta kelompok elektroakupunktur sham dan medikamentosa (n=22). Penilaian menggunakan pencitraan USG transvaginal dan perhitungan panjang siklus menstruasi sebelum dan sesudah perlakuan. Hasil penelitian menunjukkan terdapat perbedaan bermakna rerata volume ovarium antara kedua kelompok sebelum dan sesudah perlakuan (p=0,002); penurunan jumlah folikel antral (p=0,005); angka kejadian menstruasi (p=0,001); dan pemendekan siklus menstruasi (p=0,003). Kesimpulan penelitian ini elektroakupunktur dan medikamentosa memberikan perbaikan terhadap keluhan dan gambaran ovarium pada pasien SOPK.

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Polycystic Ovarian Syndrome (PCOS) is a general endocrinopathy condition that signed with oligoovulation or anovulation cycle, excess androgen production, and an image of multiple small cysts identified by transvaginal ultrasound (Rotterdam criteria, 2004). PCOS found in 10% of reproductive women and highly corresponded with ovulation dysfunction and finally decrease the fertility rate. The goal of this study is to know the effect of electroacupuncture combined with medical treatment in PCOS. A double blind randomized controlled trial is performed in 44 subjects with PCOS and divided into true electroacupuncture combined with medical treatment group (n=22) and sham electroacupuncture combined with medical treatment group (n=22). Ovarian volume and antral follicle are evaluated with transvaginal ultrasound and the length of menstrual cycle is counted before and after the treatment. The results show there are significant mean differences between ovarian volume in two groups before and after treatment (p=0,002); antral follicle count (p=0,005); menstrual incidence during the treatment (p=0,001); and shortened menstrual cycle (p=0,003). The conclusion of this study is electroacupuncture combined with medical treatment could improve PCOS patients’ compaint and ovarian image."

"ABSTRAKDepresi merupakan suatu gangguan kejiwaan pada alam perasaan, yang ditandai dengan kesedihan, hilangnya minat atau kebahagiaan, perasaan bersalah, gangguan tidur dan nafsu makan, perasaan lelah dan konsentrasi yang kurang baik. Tiga terapi utama untuk depresi yaitu psikoterapi, farmakoterapi dan electroconvulsive therapy (ECT). Selective Serotonin Re-uptake Inhibitor (SSRI) merupakan terapi antidepresan yang paling sering dipakai. Efektifitas farmakologis antidepresan hanya mencapai 60%-70%. Sebagian pasien depresi tidak merespons penuh, mengalami relaps, atau menderita efek samping yang tidak diharapkan sehingga memerlukan pengembangan terapi pilihan lain, seperti laserpunktur.Penelitian ini bertujuan untuk mengetahui efektivitas terapi kombinasi laserpunktur dengan antidepresan dan psikoterapi dibandingkan dengan terapi kombinasi laserpunktur sham dengan antidepresan dan psikoterapi terhadap perubahan skor Hamilton Rating Scale for Depression 17 (HAM-D 17) dan kadar serotonin penderita depresi. Uji klinis acak tersamar tunggal pada 33 penderita depresi dialokasikan kedalam kelompok perlakuan dan kontrol. Terdapat penurunan skor HAM-D 17 yang bermakna (p<0.001) setelah 8 kali terapi laserpunktur dan peningkatan kadar serotonin yang bermakna (p=0,004) setelah terapi.Penelitian ini menunjukkan terapi kombinasi laserpunktur dengan antidepresan dan psikoterapi efektif mengurangi gejala depresi dan meningkatkan kadar serotonin lebik baik dibandingkan terapi kombinasi laserpunktur sham dengan antidepresan dan psikoterapi saja.

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ABSTRACT

Depression is a psychiatric disorder in mood, which is characterized by sadness, loss of interest or happiness, feeling guilty or worthless, sleep or appetite disorders, feeling tired and lack of concentration. There are three main treatment for depression are psychotherapy, pharmacotherapy and electroconvulsive therapy (ECT). The effectiveness of pharmacological antidepressant only reach 60% to 70%. The majority of depressed patients do not respond fully, relapse, or suffer side effects are not expected to require the development of therapies other options, one of which laserpuncture.

This study aims to determine the effectiveness of combination therapy with antidepressants and psychotherapy laserpuncture compared with sham laserpuncture combination therapy with antidepressants and psychotherapy to change in Hamilton Rating Scale for Depression 17 (HAM-D 17) and the serotonin levels of people with depression. Single-blind randomized clinical trial was conducted on 33 patients with depression were allocated into intervention and control groups.

The results showed there is a decrease in HAM-D 17 were significantly (p <0.001). There is a significant increase serotonin levels (p = 0.004). Conclusion of the study is laserpuncture combination therapy with antidepressants and psychotherapy are effective in reducing symptoms of depression and elevating cortisol level compared to sham laserpuncture combination therapy with antidepressants and psychotherapy."

"Obesitas merupakan suatu keadaan dengan akumulasi lemak yang tidak normal atau berlebihan di jaringan adiposa sehingga dapat mengganggu kesehatan. Diperkirakan lebih dari 500 juta orang dewasa di seluruh dunia mengalami obesitas dan 1,5 miliar mengalami masalah kelebihan berat badan. Pada obesitas terdapat peningkatan jaringan adiposa dimana jaringan adiposa dapat mensintesis dan mensekresi sitokin pro-inflamasi seperti interleukin-6 (IL-6). Akupunktur telah lama dikenal sebagai salah satu terapi tambahan dalam menangani obesitas. Akupunktur dapat menurunkan respon inflamasi pada jaringan adiposa dengan menurunkan infiltrasi makrofag ke dalam jaringan adiposa pada obesitas sehingga jumlah makrofag yang merupakan sumber produksi adipokin pro-inflamasi menjadi lebih sedikit. Penelitian ini bertujuan untuk mengetahui pengaruh terapi akupunktur tanam benang catgut dan intervensi diet terhadap perubahan kadar IL-6 dan indeks massa tubuh pada pasien obesitas. Uji klinis acak tersamar ganda dilakukan pada 36 pasien obesitas yang dialokasikan ke dalam kelompok akupunktur tanam benang catgut dan intervensi diet atau kelompok akupunktur tanam benang sham dan intervensi diet. Akupunktur tanam benang dilakukan 2 kali pada titik CV12 Zhongwan, ST25 Tianshu, CV6 Qihai, dan SP6 Sanyinjiao setiap 2 minggu. Kadar IL-6 dalam plasma darah dan indeks massa tubuh digunakan untuk mengukur keluaran penelitian. Hasil penelitian menunjukkan perbedaan bermakna rerata kadar IL-6 awal dengan akhir dalam kelompok akupunktur tanam benang catgut (p = 0.01; 95% IK: 0.03 sampai 0.23) dan rerata selisih IMT lebih rendah 0.33 pada kelompok akupunktur tanam benang catgut dibandingkan dengan kelompok akupunktur tanam benang sham (p = 0.02; 95% IK: 0.05 sampai 0.61). Kesimpulan penelitian adalah terapi kombinasi akupunktur tanam benang catgut dan intervensi diet lebih efektif dalam menurunkan kadar IL-6 dan indeks massa tubuh pada pasien obesitas.

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Obesity is a condition with abnormal fat accumulation or excessive adipose tissue so it can disturb our health. It is estimated that over 500 million adults worldwide are obese and 1.5 billion are having problems with overweight. In obese there is an increased adipose tissue which can synthesize and secrete pro-inflammatory cytokines such as interleukine-6 (IL-6). Acupuncture has long been known as an adjunctive therapy for obesity. Acupuncture can reduce inflammatory responses in adipose tissue by reducing macrophage infiltration into adipose tissue in obesity so that the number of macrophages, which are the source of production of proinflammatory adipokines become fewer. A double blind randomized controlled trial involved 36 obesity patients randomly allocated into catgut embedding acupuncture group with diet intervention or sham embedding acupuncture group with diet intervention. Catgut embedding therapy was given two times at CV12 Zhongwan, ST25 Tianshu, CV6 Qihai, and SP6 Sanyinjiao every two weeks. Interleukine-6 level in blood plasma and body mass index (BMI) is used to measure research output. There was a statistically significant difference within catgut embedding group with levels of IL-6 (p = 0.01; 95% CI: 0.03 to 0.23) and lower mean BMI difference of 12.33 in catgut embedding group compared with sham embedding group (p = 0.02; 95% CI: 0.05 to 0.61). The result suggest that acupoint-catgut embedding therapy combined with diet intervention is more effective in reducing IL-6 levels and BMI in obese patients."

"ABSTRAKKolonoskopi merupakan standar penapisan neoplasia kolorektal. Salah satu komplikasi yang sering dirasakan adalah nyeri abdomen. Pemberian analgesi untuk mengurangi nyeri belum optimal sehingga berbagai modalitas terapi dikembangkan, salah satunya akupunktur telinga. Uji klinis acak tersamar dengan pembanding dilakukan pada 56 pasien yang menjalani kolonoskopi untuk mengetahui efek akupuntur terhadap nyeri. Hasil penelitian menunjukkan bahwa skor CPOT lebih rendah pada kelompok akupunktur namun tidak terdapat perbedaan bermakna terhadap skor VAS, perubahan frekuensi nadi dan rerata waktu menuju sekum. Kesimpulan penelitian ini, akupunktur telinga efektif untuk mengurangi nyeri pada kolonoskopi walaupun tidak terdapat perbedaan bermakna dengan plasebopunktur.

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ABSTRACT

Colonoscopy is the standard screening colorectal neoplasia.One of the common complication is abdominal pain. Randomized controlled trials carried out on 56 patients who underwent colonoscopy to determine acupuncture effect on pain during ciolonoscopy. The results showed CPOT was lower in the acupuncture group while there were no significant differences regarding VAS , changes in heart rate and the mean time to the cecum. Resulst suggested ear acupuncture combined with midazolam and pethidine was effective to reduce pain during colonoscopy while there were no significant differences compared to plasebopuncture."