Hasil Pencarian  ::  Simpan CSV :: Kembali

Hasil Pencarian

Ditemukan 19 dokumen yang sesuai dengan query
cover
Findra Mellya Normasiwi
Abstrak :
Telah dilakukan penelitian untuk mengetahui bahwa ekstrak etanol rimpang temu mangga Curcuma mangga Val. berpengaruh terhadap kadar bilirubin total dan bilirubin direct akibat kerusakan hati yang diinduksi oleh karbon tetraklorida CCl4 . Hewan uji yang digunakan dalam penelitian yaitu 24 ekor tikus Rattus norvegicus L. jantan galur Sprague-Dawley yang dibagi menjadi enam perlakuan KK1, KK2, KP1, KP2, KP3, dan KP4 dengan empat kali ulangan. Kelompok KK1 merupakan kelompok kontrol normal yang tidak diinjeksikan CCl4 dan dicekok CMC 0.5 , KK2 merupakan kelompok kontrol perlakuan yang diinjeksikan CCl4 sebanyak 1 ml/kgBB secara intraperitoneal dan dicekok CMC 0,5 . Kelompok KP1, KP2, KP3, dan KP4 merupakan kelompok perlakuan yang diinjeksikan CCl4 1 ml/kgBB dan diberikan ekstrak temu mangga dengan dosis berturut-turut 10 mg/kgBB, 20 mg/kgBB, 40 mg/kgBB, dan 80 mg/kgBB. Hasil uji non parametrik Kruskal-Wallis ? = 0,05 menunjukkan bahwa dosis 10 mg/kgBB, 20 mg/kgBB, 40 mg/kgBB, dan 80 mg/kgBB berpengaruh terhadap kadar bilirubin total dan bilirubin direct. Hasil uji perbandingan berganda Dunnett T3 ? = 0,05 menunjukkan bahwa dosis-dosis tersebut tidak berbeda bermakna dengan KK1. Dengan demikian dosis-dosis tersebut memiliki efek kuratif karena dapat menurunkan kadar bilirubin total dan direct sampai mendekati kadar normal. ...... This study was conducted in order to observe that the ethanol extract of mango ginger rhizome Curcuma mangga Val. affect the level of total bilirubin and direct bilirubin due to liver damage induced by tetrachloride carbon CCl4 . The test animals in the study were 24 male rats Rattus norvegicus L. of Sprague Dawley strain that was divided into six treatment KK1, KK2, KP1, KP2, KP3 and KP4 and repeated four times. The KK1 group is a normal control group that was not injected with CCl4 and 0.5 CMC fed, KK2 group is a treatment group that was intraperitoneally injected with CCl4 treatment in the amount of 1 ml kgBW and 0.5 CMC fed. KP1, KP2, KP3 and KP4 are treatment groups that got injected with CCl4 1 ml kgBB and were given mango ginger rhizome ethanol extract each with a dose of 10 mg kgBW, 20 mg kgBW, 40 mg kgBW, and 80 mg kgBW respectively by oral. The results of Kruskal Wallis non parametric test 0,05 shows that the dose of 10 mg kgBW, 20 mg kgBW, 40 mg kgBW, and 80 mg kgBW impacted on total bilirubin and direct bilirubin levels. Dunnet rsquo s T3 0,05 multiple comparison test result shows that the dosages had no significant differences with KK1 group. In conclusions, the dosages could be deemed as have curative effects since they successfully reduce the level of total bilirubin and direct bilirubin until it approached normal level.
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2017
S68302
UI - Skripsi Membership  Universitas Indonesia Library
cover
Niken Ekatiwi
Abstrak :
[ ABSTRAK
Telah dilakukan penelitian untuk mengetahui pengaruh infusa daun keluwih (Artocarpus camansi Blanco) terhadap pematangan spermatozoa mencit (Mus musculus L.) jantan di epididimis. Sebanyak 24 ekor mencit jantan dibagi menjadi 4 kelompok, yaitu kelompok kontrol (KK) yang diberikan perlakuan berupa akuades, kelompok perlakuan 1 (KP1), kelompok perlakuan 2 (KP2), dan kelompok perlakuan 3 (KP3) yang diberikan infusa daun keluwih dengan dosis berturt-turut yaitu 2,5; 5; dan 10 g/kg bb selama 8 hari. Hasil penelitian menunjukkan adanya penurunan persentase motilitas spermatozoa pada kelompok perlakuan dosis 2,5 g/kg bb dan peningkatan persentase motilitas serta abnormalitas pada dosis 5 g/kg bb dan 10 g/kg bb. Hasil penelitian menunjukkan adanya penurunan persentase viabilitas spermatozoa pada kelompok perlakuan dosis 2,5 g/kg bb; 5 g/kg bb; dan 10 g/kg bb. Hasil tersebut menunjukkan bahwa pemberian infusa daun keluwih (Artocarpus camansi Blanco) memiliki pengaruh terhadap kualitas dan kuantitas spermatozoa mencit jantan
ABSTRACT The research has been done to determine the effect of Keluwih Leaf?s infusion intake on maturation of spermatozoa of male mice in epididymis. Twenty-four male mice were divided into 4 groups; consisting of control group which were given akuades intake and treatment group which were given infusion with doses 2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw; and 10 g/kg bw. The result indicated that keluwih leaf?s infusion intake gave an impact on quality and quantity of male mice spermatozoa.;The research has been done to determine the effect of Keluwih Leaf?s infusion intake on maturation of spermatozoa of male mice in epididymis. Twenty-four male mice were divided into 4 groups; consisting of control group which were given akuades intake and treatment group which were given infusion with doses 2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw; and 10 g/kg bw. The result indicated that keluwih leaf?s infusion intake gave an impact on quality and quantity of male mice spermatozoa.;The research has been done to determine the effect of Keluwih Leaf?s infusion intake on maturation of spermatozoa of male mice in epididymis. Twenty-four male mice were divided into 4 groups; consisting of control group which were given akuades intake and treatment group which were given infusion with doses 2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw; and 10 g/kg bw. The result indicated that keluwih leaf?s infusion intake gave an impact on quality and quantity of male mice spermatozoa.;The research has been done to determine the effect of Keluwih Leaf?s infusion intake on maturation of spermatozoa of male mice in epididymis. Twenty-four male mice were divided into 4 groups; consisting of control group which were given akuades intake and treatment group which were given infusion with doses 2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw; and 10 g/kg bw. The result indicated that keluwih leaf?s infusion intake gave an impact on quality and quantity of male mice spermatozoa., The research has been done to determine the effect of Keluwih Leaf’s infusion intake on maturation of spermatozoa of male mice in epididymis. Twenty-four male mice were divided into 4 groups; consisting of control group which were given akuades intake and treatment group which were given infusion with doses 2,5; 5; and 10 g/kg bw for 8 consecutive days. The results showed that an decrease in percentage of sperm motility at doses 2,5 g/kg bw and also an increase of motility and abnormality at doses 5 g/kg bw and 10 g/kg bw. The percentage of spermatozoa viability showed a decrease result at doses 2,5 g/kg bw; 5 g/kg bw; and 10 g/kg bw. The result indicated that keluwih leaf’s infusion intake gave an impact on quality and quantity of male mice spermatozoa.]
Universitas Indonesia, 2016
S62726
UI - Skripsi Membership  Universitas Indonesia Library
cover
Arsya Ramadina Semudi
Abstrak :
Harimau sumatra merupakan salah satu spesies endemik Indonesia yang keberadaannya terancam punah (critically endangered) menurut IUCN sehingga diperlukan upaya konservasi. Konservasi harimau sumatra dilakukan Taman Margasatwa Ragunan (TMR) beserta IUCN melalui program GSMP (Global Species Management Plan) yang dilakukan secara collaborative breeding. Collaborative breeding dilakukan dengan memasangkan betina asal TMR dengan jantan hasil pertukaran dengan Medan Zoo untuk mencegah inbreeding. Pemasangan harimau harus melalui proses introduksi dan interaksi keduanya perlu diamati. Oleh karena itu, penelitian dilakukan terhadap pasangan harimau sumatra untuk menganalisis perilaku sosial yang terjadi antara harimau sumatra jantan dan betina yang mungkin mengarah ke perilaku reproduksi. Metode scan sampling dan ad libitum digunakan dalam penelitian selama tiga jam perhari dengan total pengulangan sebanyak 23 kali dari Januari hingga Maret 2024. Pengambilan data dilakukan dengan mengamati perilaku sosial dan reproduksi harimau sumatra jantan dan betina di kandang dalam Zona Harimau 1 Taman Margasatwa Ragunan. Hasil dari penelitian ini didominasi oleh perilaku sosial berupa perilaku saling mendekati (♀ 26,29%; ♂ 21,58%). Perilaku chuffing, head rubbing dan sniffing lebih sering dilakukan kedua harimau sumatra dibandingkan dengan perilaku growl dan aggression. Jantan dan betina juga melakukan perilaku reproduksi, yaitu flehmen, sedangkan mating call dan sniffing genitalia hanya dilakukan oleh jantan. Penelitian ini menunjukkan adanya perilaku sosial harimau sumatra yang mengarah pada perilaku reproduksi, yaitu perilaku chuffing, head rubbing, body rubbing, flehmen dan sniffing genitalia. ......The sumatran tiger is one of Indonesia's endemic species that is critically endangered according to the IUCN so that conservation efforts are needed. Sumatran tiger conservation is carried out by Ragunan Zoo (TMR) and IUCN through the GSMP (Global Species Management Plan) by doing collaborative breeding. Collaborative breeding is done by pairing female from TMR with male from Medan Zoo to prevent inbreeding. The pairing of tigers must go through an introduction process and their interactions need to be observed. Therefore, research was conducted on pairs of sumatran tigers to analyze the social behaviors that occurs between male and female sumatran tigers that may lead to reproductive behavior. Scan sampling and ad libitum methods were used in the study for three hours per day with a total of 23 repetitions from January to March 2024. Data were collected by observing the social and reproductive behavior of male and female sumatran tigers in sleeping cages, Tiger Zone 1 of Ragunan Zoo. The results of this study were dominated by social behavior in the form of approaching behavior (♀ 26,29%; ♂ 21,58%). Chuffing, head rubbing and sniffing behaviors were more often performed by both sumatran tigers compared to growl and aggression behaviors. Male and female sumatran tigers also perform reproductive behaviors, such as flehmen, while mating calls and genitalia sniffing are only done by male. This study shows the existence of social behavior of sumatran tigers that lead to reproductive behavior, such as chuffing, head rubbing, body rubbing, flehmen and sniffing genitalia.
Depok: Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Indonesia, 2024
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library
cover
Anjar Prianto
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2010
S31639
UI - Skripsi Open  Universitas Indonesia Library
cover
Hasna Nurul Fitri
Abstrak :
Telah dilakukan penelitian untuk mengetahui pengaruh sari buah jeruk siam Citrus nobilis Lour. dalam pengencer tris kuning telur TKT terhadap kualitas spermatozoa domba garut Ovis aries L. 24 jam pascakriopreservasi. Semen ditampung dari lima pejantan domba garut satu kali dalam satu minggu menggunakan vagina buatan. Segera setelah dievaluasi, semen diencerkan dengan pengencer tris kuning telur yang mengandung sari buah jeruk 0 KK, 5 KP 1, 10 KP 2, 15 KP 3, dan 20 KP 4. Semen dikemas dalam straw 0,25 ml dengan konsentrasi akhir 50x106 spermatozoa/ml. Semen diekuilibrasi pada suhu 5oC selama dua jam kemudian dibekukan dan disimpan dalam tabung N2 cair. Semen dievaluasi terhadap parameter motilitas, viabilitas, integritas membran, integritas akrosom, dan abnormalitas. Hasil uji ANAVA satu arah menunjukkan terdapat perbedaan nyata antar kelompok perlakuan terhadap persentase motilitas, viabilitas, dan integritas membran p < 0,05. Hasil uji lanjut Duncan menunjukkan bahwa KP 2 memiliki perbedaan nyata terhadap semua kelompok perlakuan. Berdasarkan hasil tersebut, penambahan sari buah jeruk pada konsentrasi 10 KP 2 merupakan konsentrasi terbaik yang mampu memperkecil penurunan kualitas spermatozoa domba garut pascakriopreservasi berdasarkan persentase motilitas 58,68 0,68, viabilitas 59,73 6,47, dan integritas membran 54,87 5,58. ...... The research aimed to find out the effect of siam orange juice in extender on garut ram spermatozoa quality 24 hours postcryopreseration. Semen was collected from five rams once a week using artificial vagina. Semen sample was diluted in tris egg yolk based extender containing 0 KK, 5 KP 1, 10 KP 2, 15 KP 3 and 20 KP 4 siam orange juice. Semen was packed in 0.25 ml straw with a final concentration of 50x106 spermatozoa ml. Sperm was equilibrated at 5 C for two hours then frozen and stored in a liquid nitrogen N2 tube. Sperm parameters including motility, viability, membrane integrity, acrosome integrity, and abnormality were assessed. One way ANAVA test results showed significant differences between treatment groups on the percentage of motility, viability, and membrane integrity.
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2017
S68124
UI - Skripsi Membership  Universitas Indonesia Library
cover
cover
Ovy Aulia
Abstrak :
Telah dilakukan uji teratogenik ekstrak etanol daun salam (Syzygium polyanthum Wight.) yang bertujuan untuk mengetahui pengaruh pemberian ekstrak tersebut terhadap morfologi fetus mencit (Mus musculus L.) galur DDY. Tiga puluh ekor mencit betina bunting dibagi menjadi 5 kelompok yang terdiri dari kelompok kontrol dan kelompok dosis 0,5; 5; 50 dan 500 mg/kg bb. Bahan uji diberikan secara oral sejak hari ke-6 hingga ke-15 kebuntingan. Pembedahan dilakukan pada hari ke-18 kebuntingan. Hasil penelitian menunjukkan pengaruh pemberian ekstrak etanol daun S. polyanthum pada dosis 0,5 mg/kg bb tidak menimbulkan resorpsi dan malformasi eksternal. Pada dosis 5 mg/kg bb ditemukan resorpsi (6,15%) dan fetus kelopak mata terbuka (1,63%). Pada dosis 50 dan 500 mg/kg bb ditemukan resorpsi (7,69%; 9,34%) dan fetus hemoragi (1,63%; 1,47%). Meski demikian, secara statistik (P > 0,05) pemberian ekstrak etanol daun S. polyanthum pada dosis 0,5; 5; 50 dan 500 mg/kg bb selama periode organogenesis tidak memberikan pengaruh yang signifikan terhadap perkembangan morfologi fetus mencit. ......This research was conducted to observe the teratogenic potential of S. polyanthum ethanol extract on morphology of fetal mice strain DDY. Thirty pregnant female mice were divided into 5 groups, consisting of normal group and treatment groups with dose 0.5; 5; 50 and 500 mg/bw. The extract was given orally from 6th to 15th day of gestation. The results showed that the effect of S. polyanthum ethanol extract at a dose of 0.5 mg/bw did not cause resorption and external malformation. At a dose of 5 mg/bw extract given, there were resorption (6.15%) and fetal eyelids open (1.63%). Resorption (7.69%; 9.34%) and fetal hemorrhage (1.63%; 1.47%) were found in mice given doses of 50 and 500 mg/bw. However, statistic test (P> 0.05) showed that the treatment of S. polyanthum ethanol extract at doses of 0.5; 5; 50 and 500 mg/bw during the period of organogenesis did not have a significant influence on morphology of fetal mice strain DDY.
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2016
S64835
UI - Skripsi Membership  Universitas Indonesia Library
cover
Nur Aini
Abstrak :
ABSTRAK
Telah dilakukan penelitian uji teratogenik ekstrak etanol rumput israel (Asystasia gangetica) yang bertujuan untuk mengetahui pengaruh pemberian ekstrak tersebut terhadap morfologi fetus mencit (Mus musculus L.) galur DDY. Sebanyak 30 ekor mencit betina bunting diberikan ekstrak etanol A. gangetica dengan dosis 0,5; 5; 50; dan 500 mg/kg bb selama periode organogenesis, yaitu hari ke-6 hingga ke-15 kebuntingan. Pada hari ke-18 kebuntingan, mencit bunting dikorbankan dengan cara anestesi dan kemudian dibedah. Hasil uji Anava (P > 0,05) menunjukkan bahwa tidak ada pengaruh signifikan dari pemberian ekstrak etanol A. gangetica yang diberikan selama periode organogenesis terhadap jumlah corpus luteum, fetus hidup, berat badan, dan panjang crown-rump dari fetus mencit. Hasil uji Kruskal-Wallis (P > 0,05) menunjukkan bahwa tidak ada pengaruh signifikan dari pemberian ekstrak tersebut terhadap resorpsi, hemoragi, dan perbandingan jenis kelamin dari fetus mencit di seluruh kelompok. Senyawa ekstrak etanol A. gangetica yang diberikan selama periode organogenesis tidak berpotensi teratogenik terhadap morfologi fetus mencit.
ABSTRACT
Teratogenic test of ethanol extract of rumput israel (Asystasia gangetica), which aim of this study was to determine the effects of the extract on morphology of fetal mice has been done. A total of 30 female mice (Mus musculus L.) given ethanol extract of A. gangetica with a doses of 0.5; 5; 50; and 500 mg/kg bw during the organogenesis period which is from day 6 to 15 of gestation. On the 18th day of gestation, the pregnant mice were sacrificed under deep anesthesia and a caesarean section was performed. The Anova test (P > 0.05) indicates no significant effect of treatment administered during the period of organogenesis on the number of corpus luteum, fetal life, body weight, and crown-rump length of fetal mice. The Kruskal-Wallis test (P > 0.05) indicates no significant effect of treatment on resorption, hemorrhage, and sex ratio of fetal mice in all groups. The ethanol extract of A. gangetica that given during organogenesis period has no teratogenic effects on morphology of fetal mice.
2016
S64836
UI - Skripsi Membership  Universitas Indonesia Library
cover
Dyah Ari Nugrahaningrum
Abstrak :
ABSTRAK
Telah dilakukan penelitian untuk mengetahui pengaruh pemberian fortifikan NaFeEDTA dalam tepung tempe dan susu kedelai terhadap kadar natrium plasma darah tikus (Rattus norvegicus L.) jantan galur Sprague Dawley. Sebanyak 25 ekor tikus dibagi ke dalam 5 kelompok: kelompok kontrol 1 (KK1) yang diberi CMC 0,5%, kelompok kontrol 2 (KK2) yang diberi tepung tempe atau susu kedelai, dan tiga kelompok perlakuan (KP1, KP2, KP3) yang diberi tepung tempe atau susu kedelai dengan fortifikan NaFeEDTA dosis 1,35 mg Fe/ kgBB; 2,7 mg Fe/ kgBB; 5,4 mg Fe/ kgBB selama 21 hari berturut-turut. Penentuan kadar natrium plasma dengan alat AES (Atomic Emission Spectroscopy). Hasil uji Anava satu arah (P > 0,05) menunjukkan tidak ada pengaruh nyata pemberian fortifikan NaFeEDTA dalam tepung tempe dan susu kedelai terhadap kadar natrium antar kelompok perlakuan. Kadar natrium plasma pada T21 dengan bahan uji tepung tempe dan susu kedelai tetap berada pada rentang normal antara 0,456 mg/ml -- 0,586 mg/ml.
ABSTRACT
The effect of NaFeEDTA fortificant inserted in tempeh flour and soy milk intake on plasma sodium concentration in male Sprague-Dawley rats (Rattus norvegicus L.) had been studied. Twenty five rats were divided into five groups: control group 1 (KK1) was administered with CMC 0.5%, control group 2 (KK2) was administered with tempeh flour or soy milk; three treatment groups (KP1, KP2, KP3) were administered with tempeh flour or soy milk added with fortificant NaFeEDTA 1.35 mg Fe/kgBw; 2.7 mg Fe/kgBw; 5.4 mg Fe/kgBw consecutive for 21 days. Plasma sodium concentration was measured by AES (Atomic Emission Spectroscopy). One way Anova test (P > 0.05) showed there is no significant effect of fortificant NaFeEDTA inserted in tempeh flour and soy milk intake on plasma sodium concentration in all treatment groups. Plasma sodium concentration on T21 which was administered with tempeh flour and soy milk remains in normal range between 0.456 mg/ml ? 0.586 mg/ml.
2016
S65139
UI - Skripsi Membership  Universitas Indonesia Library
cover
Ihya Chair
Abstrak :
Telah dilakukan penelitian untuk mengetahui pengaruh pemberian infusa daun kluwih terhadap spermatogenesis mencit jantan galur DDY. Sebanyak 24 ekor mencit terbagi kedalam 4 kelompok, yakni kelompok kontrol KK yang diberikan akuades, kelompok perlakuan KP1, KP2, dan KP3 yang diberikan infusa daun kluwih dengan dosis berturut-turut, yaitu 2,5; 5; dan 10 g/kg BB. Infusa daun kluwih diberikan selama 36 hari. Kemudian dilakukan pengukuran terhadap berat basah testis, pengamatan dengan angka penilaian Johnsen, dan pengukuran diameter tubulus seminiferus. Data rerata berat testis pada KK, KP1, KP2, dan KP3 berturut-turut ialah 0,307 0,030 g, 0,268 0,014 g, 0,223 0,016 g, dan 0,239 0,020 g. Data rerata diameter tubulus seminiferus KK 205,17 3,79 ?m, KP1 200,97 4,82 ?m, KP2 203,78 3,96 ?m, dan KP3 189,79 3,82 ?m. Data rerata angka penilaian metode Johnsen pada KK, KP1, KP2, dan KP3 berturut-turut adalah 9,71 0,12 , 9,63 0,08 , 9,38 0,10 , dan 9,34 0,11 . Hasil penelitian menunjukkan bahwa pemberian infusa daun kluwih Artocarpus camansi Blanco berpengaruh terhadap spermatogenesis mencit jantan pada dosis 2,5; 5; dan 10 g/kg BB. ......The research has been done to determine the effect of Kluwih leaf rsquo s infusion intake on spermatogenesis of male mice DDY strain. 24 males mice have divided into 4 experimental group control group which only given aquades and treament group which given infusion with doses 2,5 5 10 g kg bw. Test material administated for 36 consecutive days. Then measured the weight of testis, observations with numerical of Johnsen scores, and the diameter of the tubules seminiferous. Mean of testes weigth KK 0,307 0,030 g, KP1 0,268 0,014 g, KP2 0,223 0,016 g, and KP3 0,239 0,020 g. Mean of diameter of tubules seminferous KK 205,17 3,79 m, KP1 200,97 4,82 m, KP2 203,78 3,96 m, and KP3 189,79 3,82 m. Mean of numerical of Johnsen score KK 9,71 0,12 , KP1 9,63 0,08 , KP2 9,38 0,10 , and KP3 9,34 0,11 . Based on LSD test.
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2016
S66631
UI - Skripsi Membership  Universitas Indonesia Library
<<   1 2   >>