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Abstrak :
ABSTRAK
Fruktooligosakarida (FOS) dan inulin memberikan pengaruh yang bervariasi terhadap bifidobakteri antar individu. Penelitian ini bertujuan untuk mengetahui hubungan antara asupan serat, FOS, dan inulin terhadap bifidobakteri. Pemeriksaan bifidobakteri pada feses anak usia 3-8 tahun di Jakarta dilakukan dengan quantitative PCR. Asupan gizi diperoleh dari wawancara menggunakan semi-quantitative food frequency questionnaire. Total bifidobakteri adalah 5.94 log10 DNA/gram feses. Analisis regresi linier berganda tidak menunjukkan adanya hubungan (P>0.05) antara inulin (95% CI = -0.015 ? 0.045) dan FOS (95% CI = -0.097 ? 0.158) dengan bifidobakteri; begitupun dengan serat. Kesimpulan dari penelitian ini adalah konsumsi FOS, inulin, dan serat tidak menunjukkan hubungan yang bermakna dengan jumlah bifidobakteri pada anak usia pra-sekolah di Jakarta.

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ABSTRACT
Fructooligosaccharides (FOS) and inulin in promoting bifidobacteria showed variability between individuals. The aim was to assess the associations between fibre, FOS, and inulin intakes and bifidobacteria. Faecal bifidobacteria was determined using quantitative PCR among children aged 3 ? 8 years in Jakarta. Nutrient intakes were based on interview using a semi-quantitative food frequency questionnaire. Total bifidobacteria was 5.94 log10 DNA/gram faeces. Multivariate linear regression analysis indicated inulin (95% CI = -0.015 ? 0.045) and FOS (95% CI = -0.097 ? 0.158) showed no association (P>0.05) with bifidobacteria; as well as fibre. In summary, FOS, inulin, and fibre consumptions showed no significant association with bifidobacteria among preschool children in Jakarta.

Abstrak :
Kurangnya penelitian mengenai transisi pada pola asupan dan marker inflamasi usus pada anak gemuk. Studi ini bertujuan untuk melihat hubungan anatara pola asupan dan fecal calprotectin pada anak prasekolah.Studi potong lintang ini dilakukan pada 101 anak dengan BMI Z score > 1 SD dengan median 2.26 (1.61, 3.43) SD serta menggunakan semiquantitative food frequency questionnaires yang telah divalidasi dimana, pola asupan diperoleh dengan menggunakan principal component analysis. Hasil studi menunjukkan 66% anak mempunyai kadar fecal calprotectin > 50 µg/g dan berhubungan dengan BMI Z score (p=0.05, r=1.89). Pola asupan (healthy pattern p=0.132, western pattern p=0.555, staple pattern p=0.541 and milk pattern p=0.534) ditemukan tidak berhubungan dengan inflamasi saluran cerna. Penelitian lebih lanjut dibutuhkan untuk mengkonfirmasi hasil studi ini dengan menggunakan pendekatan lain dan kombinasi antar marker inflamasi usus. ......Lack of study confirmed the relationship between transition of diets and gut inflammation marker in obese children. Our study aimed to investigate the association between dietary pattern and fecal calprotectin level in preschool children. A cross sectional study was conducted in 101 children with body mass index (BMI) Z-score > 1 SD and median 2.26 (1.61, 3.43) SD using validated semi quantitative food frequency questionnaires whereas dietary patterns were revealed by principal component analysis. We found 66% children had fecal calprotectin levels > 50 µg/g. The fecal calprotectin level correlated with BMI Z score (p=0.05, r=1.89). Major dietary patterns were revealed: healthy pattern (p=0.132), western pattern (p=0.555), staple pattern (p=0.541) and milk pattern (p=0.534) and multivariate analysis showed no significant association with fecal calprotectin even after full adjustment for age, sex, sedentary physical activity, BMI Z score, fat intake and total fibre intake. Our findings acknowledged the insignificant association diet with gut inflammation marker had been observed due the baseline characteristic BMIZ score of the children more contribute to the elevated of fecal calprotectin level. Further investigations are warranted with a specific inflammatory food approach using a combination of marker gut inflammation.