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"Latar belakang: Syringomyelia merupakan rongga kistik patologis pada medulla spinalis yang menyebabkan kelainan kronis, progresif dan degeneratif. Etiologi paling sering yaitu sebagai komplikasi dari malformasi chiari tipe 1. Saat ini belum ada tatalaksana spesifik untuk syringomyelia. Tatalaksana bertujuan untuk mengurangi tekanan di dalam rongga subarachnoid. Salah satu pilihan pembedahan pada syringomyelia antara lumboperitoneal shunt (LPS). Sebelum dilakukan LPS setiap pasien dilakukan lumbal pungsi (LP) terlebih dahulu untuk memastikan apakah pasien tersebut responsif secara klinis terhadap drainase CSF. Lumbal pungsi merupakan prosedur sederhana yang bisa dilakukan di hampir setiap tipe rumah sakit, sehingga dapat dipertimbangkan menjadi tatalaksana awal pada kasus syringomyelia akibat CM tipe 1.Metode: Penelitian observasional dengan desain studi potong lintang.terkait CM tipe 1 pascaHasil: Sebanyak tujuh pasien terdiagnosis syringomyelia e.c chiari malformation tipe I terdiagnosa di RSUPN Cupto Mangunkusumo. Seluruh pasien adalah Wanita dengan range usia 38-57 tahun. Diketahui ketujuh pasien mengalami keluhan berupa defisit sensorik, kelemahan subjektif, dan nyeri disestetik yang menetap/ kronik dengan skala nyeri bervariasi antara 5-7 (skala nyeri numerik rating scale (0-10). Setelah dilakukan tindakan LPS diketahui sebanyak 4 pasien mengalami perbaikan signifikan defisit sensorik. Seluruh pasien delaporkan mengalami perbaikan nyeri dimana 4 pasien mengalami resolusi sempurna. Dilaporkan satu pasien mengalami efek samping berupa migrasi shunt sehingga diperlukan tatalaksana tambahan berupa reposisi shunt.Simpulan: Pada ketujuh pasien serial kasus mengalami perbaikan pasca dilakukan LP sehingga dilanjutkan dengan LPS satu minggu sesudahnya. Hasilnya menunjukkan perbaikan klinis yang cukup signifikan pada seluruh pasien.......Background: Syringomyelia is a pathological cystic cavity in the spinal cord that causes chronic, progressive and degenerative disorders. The most common etiology is as a complication of type 1 chiari malformation. Currently, there is no specific treatment for syringomyelia. Treatment aims to reduce pressure in the subarachnoid space. One of the surgical options for syringomyelia is a lumboperitoneal shunt (LPS). Prior to LPS, each patient was subjected to a lumbar puncture (LP) to determine whether the patient was clinically responsive to CSF drainage. Lumbar puncture is a simple procedure that can be performed in almost every type of hospital, so it can be considered as the initial treatment in cases of syringomyelia due to type 1 CM.Methods: Observational study with a cross-sectional design. The sample in this study were all patients with syringomyelia related to CM type 1 after lumboperitoneal shunt surgery at Cipto Mangunkusumo General Hospital from January 2017 to December 2021, a total of 7 people.Results: A total of seven patients diagnosed with syringomyelia e.c chiari malformation type I were diagnosed at the Cupto Mangunkusumo General Hospital. All patients were women with an age range of 38-57 years. It is known that the seven patients experienced complaints in the form of sensory deficits, subjective weakness, and persistent/chronic dysesthetic pain with pain scales varying between 5-7 (numerical pain rating scale (0-10). After the LPS procedure, it was found that 4 patients experienced significant improvement. sensory deficit. All patients reported experiencing pain improvement where 4 patients experienced complete resolution.One patient reported side effects in the form of shunt migration so that additional management was needed in the form of shunt repositioning.Conclusion: The seven case series patients experienced improvement after LP was carried out so that they were continued with LPS one week afterward. The results showed significant clinical improvement in all patients."

"Praktek Kerja Profesi Apoteker di Suku Dinas Kesehatan Kota Administrasi Jakarta Barat bertujuan untuk memahami tugas dan fungsi Suku Dinas Kesehatan Kota Jakarta Utara dan juga memahami tugas pokok dan fungsi dari bagian tenaga kesehatan, bagian standarisasi mutu kesehatan dan bagian farmasi, makanan dan minuman yang termasuk di dalam seksi sumber daya kesehatan (SDK). Sedangkan tujuan dari tugas khusus adalah untuk membuat Standar Operasional Prosedur sebagai pedoman kerja petugas di apotek puskesmas Kecamatan Palmerah dalam pemberian pelayanan kefarmasian kepada pasien. ......Pharmacists Professional Practice in Health Agency of West Jakarta Administration aims to understand the duties and functions of parts of North Jakarta Health Office and also to understand the duties and functions of the part of health personnel, parts standardization and quality health pharmacy, food and beverage included in the resources in the health section (SDK). While the purpose of the special task is to make a Standard Operational Procedure for pharmaceutical care."

"Latar Belakang: Berdasarkan alat yang digunakan, pendekatan operasi kraniofaringioma terbagi menjadi endoskopik dan mikroskopik. Masing-masing pendekatan memiliki kelebihan dan kekurangan masing-masing sehingga akan memberikan luaran klinis, resektabilitas dan efektifitas pembiayan yang berbeda-beda. Belum diketahui luaran pasca operasi baik pendekatan mikroskopik maupun endoskopik di RSUPN dr. Cipto Mangunkusumo.Tujuan: Mengetahui luaran operasi pasien kraniofaringioma di RSUPN dr. Cipto Mangunkusumo..Metode: Kohort retroprospektif pasien kraniofaringioma yang menjalani pembedahan sejak tahun 2012 hingga tahun 2021 di RSUPN dr. Cipto Mangunkusumo, Jakarta, Indonesia. Pasien dengan masalah ekstrakranial, pasien endoskopi dengan kraniotomi luas dikeluarkan dari penelitian. Dilakukan pengambilan data demografis, luaran klinis dan resektabilitas tumor dan efektifitas pembiayaan. Data dikelompokkan menjadi variabel kategorik dan numerik. Analisa variabel kategorik dan kategorik diolah menggunakan uji Chi-square. Sedangkan variabel kategorik dan numerik diolah menggunakan T-Test. Pengolahan data menggunakan SPSS 25.0. Hasil: Pada 30 subjek penelitian, 22 subjek (73%) menjalani tindakan operasi mikroskopik dan 8 subjek (27%) menjalani tindakan operasi endoskopik. Perdarahan intraoperasi rata-rata pendekatan mikroskopik 445ml (50-1600), sedangkan endoskopik 57ml (20-200). Secara signifikan perdarahan intraoperasi pendekatan endoskopik lebih rendah dibandingkan pendekatan mikroskopik, p < 0,01. Durasi operasi rata-rata pendekatan mikroskopik 3 jam (2-4jam), sedangkan endoskopik 6,6jam (2,5-14jam). Secara signifikan waktu operasi pendekatan endoskopik lebih singkat dibandingkan mikroskopik, p=0,001. Kesimpulan: Pendekatan endoskopik memiliki potensi yang baik untuk dikembangkan sebagai pilihan tatalaksana bedah pasien kraniofaringioma.......Based on the equipment used, the surgical approach to craniopharyngioma is divided into endoscopic and microscopic. Each approach has its own advantages and disadvantages so that it will provide different clinical outcomes, resectability, and cost effectiveness. The postoperative outcome for both microscopic and endoscopic approaches in RSUPN dr. Cipto Mangunkusumo is unknown.Objective: Knowing the operative approach outcome of craniopharyngioma patients at RSUPN dr. Cipto Mangunkusumo. Methods: A retrospective cohort of craniopharyngioma patients undergoing surgery from 2012 to 2021 at RSUPN dr. Cipto Mangunkusumo, Jakarta, Indonesia. Patients with extracranial problems, assisted endoscopic approach were excluded from the study. Demographic data, clinical outcome, and tumor resectability and cost effectiveness were collected. The data are grouped into categorical and numeric variables. The analysis of categorical and categorical variables was processed using the Chi-square test. Meanwhile, categorical and numerical data were processed using T-Test. Data processing using SPSS 25.0. Results: In 30 study subjects, 22 subjects (73%) underwent microscopic surgery and 8 subjects (27%) underwent endoscopic surgery. Intraoperative bleeding using microscopic approach average 445ml (50-1600), while endoscopic 55ml (20-200). Intraoperative bleeding was significantly lower in the endoscopic approach than the microscopic approach, p<0.01. The average duration of surgery for the microscopic approach is 3 hours (2-4 hours), while the endoscopic approach is 6.6 hours (2.5-14 hours). The operating time for the endoscopic approach was significantly shorter than the microscopic one, p=0.001. Conclusion: The endoscopic approach has good potential to be developed as a surgical treatment option for craniopharyngioma patients."

"ABSTRAKTujuanTindakan bedah saraf, diduga dapat mengentikan atau memperlambat cedera otak sekunder, yang berhubungan dengan proses neuroinflamasi. Peneliti bertujuan untuk mengetahui peranan neuroinflamasi (Il-6) terhadap prognosis pasien cedera otak dan untuk mengetahui hubungan tindakan operasi dengan kondisi neuroinflamasi.MetodePenelitian ini bersifat prospektif observasional dengan desain cross sectional. Dari 40 pasien cedera otak yang dilakukan tindakan operasi, dilakukan pemeriksaan kadar Il-6 sebelum operasi dan 1 hari pasca tindakan operasi. GCS dinilai saat di UGD (GCS awal) dan sesudah tindakan operasi (GCS hari ke-7). GOS dinilai setelah bulan ke-1 dan bulan ke-3 pasca trauma. Kadar IL-6 sebelum operasi dan 1 hari pasca tindakan operasi dihubungkan dengan nilai GCS awal, GCS hari ke-7, GOS bulan ke-1 dan GOS bulan ke-3 untuk mengetahui hubungan tindakan operasi dengan proses neuroinflamasi dan nilai prognostiknya terhadap pasien cedera otak.GCS awal. GCS hari ke-7 dikelompokkan menjadi GCS <=8 dan GCS >8. GOS bulan ke-1 dan bulan ke-3 dikelompokkan menjadi GOS favorable (>3) dan unfavorable <=3.HasilKadar Il-6 awal berhubungan bermakna dengan GCS awal (p: 0.001) dengan OR 11.4 --> pasien dengan kadar Il-6 >100 pg/ml memiliki peluang 11.4 kali mendapatkan nilai GCS <=8. Terdapat perbedaan nilai median kadar Il-6 pasca operasi dibandingkan dengan pre operasi, dengan kecenderungan kadar Il-6 pasca operasi (median=35.55 pg/ml) lebih rendah daripada kadar Il-6 awal (median=76.74 pg/ml)Kadar Il-6 pasca operasi berhubungan bermakna dengan GCS hari ke-7 (p=0.006), dengan OR 24 --> pasien dengan Il-6 pre op <= 100 pg/ml memiliki peluang 24 kali memperoleh nilai GCS hari ke-7 >8. Kadar Il-6 pasca operasi berhubungan bermakna dengan GOS bulan ke-3 (nilai p= 0.016) dengan OR 11.6 --> pasien dengan kadar Il-6 <=100 pg/ml memiliki peluang sebesar 11.6 kali mencapai GOS bulan ke-3 favorable.SimpulanProses neuroinflamasi memiliki nilai prognostik pada pasien cedera otak, di mana maikin tinggi kadar Il-6 serum awal, makin buruk GCS awal pasien.Tindakan bedah saraf dapat menurunkan proses neuroinflamasi dan berhubungan dengan outcome GCS hari ke-7 (status kesadaran) pasca operasi dan GOS bulan ke-3 (kualitas hidup) yang lebih baik.

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ABSTRACTObjectivesNeurosurgical procedures are performed to stop or slow down the secondary brain injury. This study is aimed to determine the association of neuroinflammation with the prosnosis of brain injury patients and the association of neurosurgical procedure with the neuroinflammation.MethodThe study design is a prospective observation of 40 brain injuty patients who were operated. Examination were carried out top measured Il-6 serum level of pre and one day post operation on brain injury patients, and to analize therir association with GCS,GOS and neurosurgical procedures.ResultsThe Il-6 serum level pre surgery was significantly associated with initial GCS (p value=0.001 and OR 11.4). There was significant median difference of Il-6 post surgery compared with pre surgery, with a downward trend of Il-6 post surgery.The post operative Il-6 level was significantly associated with GCS 7 days post surgery (p=0.006), with OR 24, meaning that patients with post surgery level of Il-6 <= 100 pg/ml had 24 times chance of getting GCS 7 days post trauma >8. The post operative Il-6 serum was significantly associated with GCA 3 months post trauma (p value= 0.016) with OR 11.6, meaning that the patients with post operative Il-6 level <= 100 pg/ml has 11.6 times as much chance of reaching the 3 months post trauma GOS favorable.ConclusionNeuroinflammation may have prognostic values in brain injured patients. Neurosurgical procedures can decrease the neuroinflammation process and was associated with better conciousness state (GCS) and neurological outcome (GOS)."

"Pendahuluan: Perdarahan Intraventrikel Intraventricular Hemorrhage / IVH merupakan perdarahan spontan yang terjadi di dalam sistem ventrikel, 30-45 sering berhubungan dengan Intracerebral Hemorrhage ICH . Evaluasi aktifitas sehari-hari yang akurat dan tepat pada pasien pasca stroke sangat penting untuk kualitas perawatan dan pengukuran luaran pasca perawatan stroke. Modified Rankin Scale mRS merupakan skala pengukuran disabilitas yang dipakai secara global untuk evaluasi pemulihan dari stroke. Tujuan: Menelaah data luaran penderita perdarahan intraventrikel yang dilakukan operasi di Departemen Bedah Saraf Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo berdasarkan mRS. Metode: Penelitian ini merupakan penelitian retrospektif dengan desain potong lintang cross sectional . Adapun variabel independent yaitu lokasi lesi perdarahan intraserebral, IVH-skor, GCS awal, dan variabel dependent yaitu luaran berdasarkan skoring mRS. Subjek penelitian adalah semua pasien penderita perdarahan intraventrikel yang dikelola Departemen Bedah Saraf RSUPN Cipto Mangunkusumo selama periode Januari 2010 sampai dengan Agustus 2016. Jumlah sampel pada penelitian ini didapatkan 23 sampel. Data penelitian diperoleh melalui catatan rekam medis, subjek dihubungi via telepon, kemudian subjek atau keluarga diwawancara untuk menilai status fungsionalnya dengan mRS. Data diolah dengan menggunakan program SPSS 21. Hasil: Luaran 6 bulan IVH dengan menggunakan mRS secara keseluruhan didapatkan independent 11 pasien 47,8 dependent 4 pasien 17,3 dan 8 pasien meninggal 34,9 . IVH sebagian besar berusia di bawah 60 tahun 60,8 dan 39,2 yang berusia diatas 60 tahun, dari penelitian didapatkan IVH skor terbanyak adalah >15 sebanyak 15 pasien 65,2 . GCS rata-rata 7,6 2,14 . MAP terbanyak adalah >100 dengan jumlah 20 pasien 87 , dan faktor resiko yang mengalami hipertensi sebanyak 19 pasien 82,6. Diskusi: mRS dapat digunakan sebagai standar penilaian luaran IVH. ......Introduction: Intraventricular hemorrhage IVH is a spontaneous hemorrhage occurring within the ventricular system, 30 40 often associated with Intracerebral hemorrhage ICH, Accurate and precise daily evaluating activity in post stroke patients is critical for the quality of care and measurement of post stroke outcomes. Modified Rankin Scale mRS is a global disability measurement scale used for the evaluation of stroke recovery. Aims: Configuring outcome data of patient with intraventricle hemorrhage operated at neurosurgery departmen of cm hospital based on mRS. Methods This was an observational study with cross sectional design. The independent variables are location of intracerebral hemorrhage lesion, IVH score, initial GCS, and dependent variable is outcome based on mRS scores. Subjects of research were all patients with intraventricular hemorrhage administered by Department of Neurosurgery Cipto Mangunkusumo Hospital during January 2010 until August 2016 period. The number of samples in this study were obtained 23 samples. Research data was obtained through medical record and transferred into data entry format, patients was contacted by telephone, then patients or family were interviewed to assess their functional status with Modified Rankin Scale. Data is processed by using SPSS 21 program. Results: 6 months IVH overall outcomes are 11 independent patients 47.8 4 dependent patients 17.3 and 8 patients died 34.9. IVH were mostly under 60 years old 60,8 and 39,2 were aged over 60 years, from the study obtained IVH most scores were 15 as many as 15 patients 65.2. GCS averages 7.6 2.14 . Most MAPs were 100 with 20 patients 87, and hypertension risk factors were 19 patients 82.6. Discussion: mRS can be used as standard outcome assessment of IVH."

"Latar Belakang: Di era ini, terapi dengan sel punea untuk mengobati berbagaipenyakit semakin dirninati. Sejauh ini, banyak pendapat mengenai keamanan selpunea, yang dikatakan aman untuk manusia. NaIllun" belum ada penelitian lebihjauh mengenai keamanan sel punea yang disuntikan lewat vena, untuk kesehatanpembuluh darah. Tujuan dari peneiitian ini adalah untuk menganalisis efek selpunea yang disuntikkan secara IV, pada pembuluh darah arteri yang nannal.Metode: Data didapatkan dari eksperimen klinik tikus Wistar yang dilaksanakandi Instilut Pertanian Bogor, merupakan studt awal pada tikus dengan tekanan darahnormal. Tikus dengan tekanan darah nonnal (140/100 mmHg, diukur denganCODA) tersebut dibagi menjadi 3 kelompok. Kelompok pertama ada kelompokkontrol, kelompok kedua disumikan secara IV sel punca 1 x 106 , dan kelompokkeliga 3xl 06 sel, dalam sekali penyuntikan. Kelompok kedua dan ketiga diamatiselama 1 bulan setelah penyuntikan sel punca. Setelah 1 bulan, tikus dinekropsidalam keadaan anastesi. Selanjutnya, dengan bantuan J Image Software, dilakukanpcngamatan terhadap diameter dan ketebalan dinding dari meri karotis, karotisinterna, karotis eksterna, aorta abdominal, iliaka kiri, dan iliaka kanan. Analisisstatistik dilakukan dengan metode ANOV A terhadap 3 kelompok tikus untuk.mengukur perbedaan diameter pembuluh darah dan ketebalan dinding pembuludarah. Jika persebaran data tidak rata, maka digunakan metode T Independent Test.Hasil: Hasil analisis menunjukkan bahwa tidak ada perbedaan signifikan dalamdiameter dan ketebalan dinding untuk kelompok I, kelompok 2, dan kelompok 3untuk semua pembuluh darah kecuali arteri iliaka kiri. Arteri iliaka kirimenunjukkan perbedaan yang bennakna dalam diameter dan ketebalan pembuluhdarah.Diskusi: Hasil riset ini, memmjukkan keamanan sel punca pada arteri biladisuntikan ke dalam vena. Ini ditunjukkan dengan hasil yang tidak. terdapatperbedaan bermakna dalam 5 pembuluh darah yang dipenksa. kecuali arteri iliakakiri menunjukkan hasil yang bermaknadan perlu diteliti lebih lanjutdenganjumlahsam pel yang memadai (30 tikus). Setiap kelompok mempunyai sampel minimum9 ekor, namun dan hasil penelitian masing-masing kelompok mempunya 5 ekortikus yang dapat dianalisis. Sehingga hasil analisis yang didapatkan tidak bisamencerminkan hubungan yang kuat secara statistik, namun merupakan suatukecenderungan."

"Latar Belakang: Perdarahan intraserebral spontan (PISS) berkaitan dengan luaran yang buruk dibandingkan dengan infark serebral, dapat menyebabkan disabilitas berat, yaitu menyebabkan kecacatan fisik, psikologis, dan fungsi sosial. Pada pasien yang secara CT scan terbukti terdapat hematom intraserebral supratentorial, pembedahan dan perawatan neurointensif mengurangi angka kematian atau kecacatan dibandingkan hanya dengan terapi medis saja. Pembedahan yang dilakukan dapat meningkatkan luaran pasien dengan PISS yang selektif. Tujuan: Menilai luaran 6 bulan pasca operasi penderita perdarahan intraserebral spontan supratentorial yang di kelola Departemen Bedah Saraf RSUPN Dr. Cipto Mangunkusumo periode Januari 2013-Agustus 2014 serta faktor-faktor yang mempengaruhi luaran tersebut. Metode: Penelitian ini merupakan penelitian potong lintang terhadap pasien perdarahan intra serebral spontan supratentorial yang dilakukan operasi evakuasi hematom di Departemen Bedah Saraf RSUPN Dr. Cipto Mangunkusumo periode Januari 2013-Agustus 2014 menggunakan modified Rankin Scale (mRS). Data penelitian ini diperoleh melalui catatan rekam medis. Hasil: Luaran 6 bulan setelah dilakukan operasi didapatkan luaran independent 7 pasien (38,9%) dan dependent 11 pasien (61,1%). Tidak didapatkan pasien meninggal selama follow up 6 bulan setelah operasi dari data ini. Berdasarkan lokasi perdarahan supratentorial, perdarahan lobar dengan luaran lebih baik dimana luaran independent 50% dibandingkan perdarahan deep seated dengan luaran independent 16,7%. Faktor faktor yang mempengaruhi seperti jenis kelamin, GCS, volume hematom, komorbiditas hipertensi serta diabetes melitus dan jenis tindakan tidak dapat dilakukan uji kemaknaan karena jumlah sampel yang sedikit. Kesimpulan: Luaran 6 bulan PISS supratentorial pasca operasi evakuasi hematom secara keseluruhan didapatkan lebih banyak dependent dibandingkan independent, dimana pasien perdarahan intraserebral spontan supratentorial lobar lebih baik dibandingkan dengan deep seated. ......Background: Spontaneous intracerebral hemorrhage associated with poor outcomes compared with cerebral infarction, can cause severe disability, that causes physical disability, psychological, and social functioning. In patients who are the CT scan proved there supratentorial intracerebral hematoma, surgery and neurointensive care reduce mortality or disability compared only with medical therapy alone. Surgery can improve the outcome of patients with selective spontaneous intracerebral hemorrhage. Purpose: Assessing outcomes 6 months postoperatively supratentorial spontaneous intracerebral hemorrhage patients who managed the Department of Neurosurgery Dr. Cipto Mangunkusumo Hospital, the period January 2013-August 2014 and the factors that affect these outcomes. Method: A cross sectional study on patients with supratentorial spontaneous intracerebral hemorrhage and evacuation operation conducted in the Department of Neurosurgery Dr. Cipto Mangunkusumo Hospital the period January 2013-August 2014. Evaluate outcomes using the modified Rankin Scale (mRS). The research data was obtained through medical record. Result: Outcome 6 months after surgery obtained independent outcomes 7 patients (38.9%) and dependent 11 patients (61.1%). There were no patients died during the follow-up 6 months after surgery of this data. Based on the location supratentorial hemorrhage, lobar hemorrhage with better outcomes in which the outcome of the independent 50% compared to the deep-seated bleeding with independent outputs of 16.7%. Factors influencing such as sex, GCS, hematoma volume, comorbid hypertension and diabetes mellitus and type of action can not be performed because of the significance of test sample size slightly. Conclusion: Outputs 6 months postoperatively PISS supratentorial hematoma evacuation as a whole gained more dependent than independent, which supratentorial spontaneous intracerebral hemorrhage patients with lobar better than the deep-seated."

"ABSTRAK Operasi dekomprasi vaskular mikro telah diterima sebagai tatalaksana definitif pada berbagai keluhan akibat kompresi mekanik pada kompleks neurovaskular. Tindakan eksplorasi fossa posterior diketahui berhubungan dengan komplikasi gangguan fungsi serebellar dan saraf kranial. Diperlukan adanya evaluasi pasca operasi yang mengintegrasikan aspek pemulihan atas keluhan, dan komplikasi terkait tindakan, dalam menilai luaran pasien secara menyeluruh.TujuanMenilai luaran pasca operasi dekompresi vaskular mikro pada penderita sindrom kompresi kompleks neurovaskular yang dikelola Departemen Bedah Saraf RSUPN Dr. Cipto Mangunkusumo periode Januari 2011-Oktober 2015 menggunakan efficacy, complication, total score (ECT score) serta faktor-faktor yang mempengaruhi luaran.MetodePenelitian ini merupakan penelitian historikal prospektif terhadap pasien pasca operasi dekompresi vaskular mikro dengan sindrom kompresi kompleks neurovaskular yang dikelola Departemen Bedah Saraf RSUPN Dr. Cipto Mangunkusumo periode Januari 2011-Oktober 2015. Sebagai pembanding digunakan data luaran menurut publikasi ECT score orisinil. Data penelitian ini diperoleh melalui catatan rekam medis.HasilSejak Januari 2011 sampai dengan Oktober 2015, didapatkan 21 pasien trigeminal neuralgia primer dan 11 pasien hemifasial spasme primer yang dilakukan tindakan microvascular decompression. Sebanyak 15 pasien trigeminal neuralgia telah melalui periode lebih dari satu tahun pasca operasi dengan hasil luaran excellent (T-0) 13 pasien (87%), good (T-1) 1 pasien (6%), fair (T-2) 0 pasien, poor (T3-5) 1 pasien (6%). Sebanyak 11 pasien hemifasial spasme primer telah melalui periode lebih dari satu tahun pasca operasi dengan hasil luaran excellent (T-0) 5 pasien (62,5%), good (T-1) 2 pasien (25%), fair (T-2) 0, poor (T3-5) 1 pasien (12,5%). Penelitian ini memiliki jumlah sampel yang terbatas dan tidak didapatkan faktor yang mempengaruhi luaran KesimpulanSkor ECT terbukti bermanfaat dalam menilai luaran pasien paska MVD di RSCM. Jumlah pasien trigeminal neuralgia primer yang sembuh sempurna tanpa komplikasi (T0) di RSCM didapatkan 13 pasien dari 15 pasien. Jumlah luaran pasien hemifasial spasme primer yang sembuh sempurna tanpa komplikasi (T0) di RSCM didapatkan 5 pasien dari 8 pasien. ABSTRACTOutcome of Neurovascular Compression Syndrome Based on Efficacy Complication Total Score in FKUI-RSUPNCM, 2011-2015BackgroundMicrovascular decompression has been administered as neurosurgical armamentary as definitive treatment of mechanical compression of neurovascular. Posterior fossa approach also related to post operative cerebellar and cranial nerve dysfunction. An integrated evaluation combining efficacy and complication of surgical exploration is crucial to determine a comprehensive outcome of post surgical patients.PurposeTo evaluate outcome of microvascular decompression surgery in patient diagnosed with neurovascular compression syndrome managed by Department of Neurosurgery RSUPN Dr. Cipto Mangunkusumo, January 2011-October 2015 based on efficacy, complication, total score (ECT score) and related factors.MethodA historical prospective study on patients diagnosed with neurovascular compression syndrome managed by Department of Neurosurgery RSUPN Dr. Cipto Mangunkusumo, January 2011-October 2015 based on efficacy, complication, total score (ECT score). The result is compared with the original publication of ECT score outcome. Research data was obtained through medical records.ResultsTwenty one patients diagnosed with trigeminal neuralgia and 11 patients diagnosed with hemifacial spasm were treated by microvascular decompression surgery since January 2011 - October 2015. In trigeminal neuralgia group shown fifteen patients with more than one year post operative period with categorized outcome : 13 patients (87%) excellent (T-0), 1 patient (6%) good (T-1), 0 patient fair (T-2), 1 patient (6%) poor (T3-5). In hemifacial spasm group shown 11 patient with more than one year post operative period with categorized outcome : 5 patient (62,5%) excellent (T-0), 2 patient (25%) good (T-1), 0 patient fair (T-2), 1 patient (12,5%) poor (T3-5). Sample size of research were limited and related to insignificant findings of related factors. ConclusionEfficacy complication total score is efficient in evaluating post microvascular decompression surgery outcome. Trigeminal neuralgia group shown 13 of 15 patients with excellent outcome (T0). Hemifacial spasm group shown 5 of 8 patients with excellent outcome (T0).;TitleOutcome of Neurovascular Compression Syndrome Based on Efficacy Complication Total Score in FKUI-RSUPNCM, 2011-2015BackgroundMicrovascular decompression has been administered as neurosurgical armamentary as definitive treatment of mechanical compression of neurovascular. Posterior fossa approach also related to post operative cerebellar and cranial nerve dysfunction. An integrated evaluation combining efficacy and complication of surgical exploration is crucial to determine a comprehensive outcome of post surgical patients.PurposeTo evaluate outcome of microvascular decompression surgery in patient diagnosed with neurovascular compression syndrome managed by Department of Neurosurgery RSUPN Dr. Cipto Mangunkusumo, January 2011-October 2015 based on efficacy, complication, total score (ECT score) and related factors.MethodA historical prospective study on patients diagnosed with neurovascular compression syndrome managed by Department of Neurosurgery RSUPN Dr. Cipto Mangunkusumo, January 2011-October 2015 based on efficacy, complication, total score (ECT score). The result is compared with the original publication of ECT score outcome. Research data was obtained through medical records.ResultsTwenty one patients diagnosed with trigeminal neuralgia and 11 patients diagnosed with hemifacial spasm were treated by microvascular decompression surgery since January 2011 - October 2015. In trigeminal neuralgia group shown fifteen patients with more than one year post operative period with categorized outcome : 13 patients (87%) excellent (T-0), 1 patient (6%) good (T-1), 0 patient fair (T-2), 1 patient (6%) poor (T3-5). In hemifacial spasm group shown 11 patient with more than one year post operative period with categorized outcome : 5 patient (62,5%) excellent (T-0), 2 patient (25%) good (T-1), 0 patient fair (T-2), 1 patient (12,5%) poor (T3-5). Sample size of research were limited and related to insignificant findings of related factors. ConclusionEfficacy complication total score is efficient in evaluating post microvascular decompression surgery outcome. Trigeminal neuralgia group shown 13 of 15 patients with excellent outcome (T0). Hemifacial spasm group shown 5 of 8 patients with excellent outcome (T0).;TitleOutcome of Neurovascular Compression Syndrome Based on Efficacy Complication Total Score in FKUI-RSUPNCM, 2011-2015BackgroundMicrovascular decompression has been administered as neurosurgical armamentary as definitive treatment of mechanical compression of neurovascular. Posterior fossa approach also related to post operative cerebellar and cranial nerve dysfunction. An integrated evaluation combining efficacy and complication of surgical exploration is crucial to determine a comprehensive outcome of post surgical patients.PurposeTo evaluate outcome of microvascular decompression surgery in patient diagnosed with neurovascular compression syndrome managed by Department of Neurosurgery RSUPN Dr. Cipto Mangunkusumo, January 2011-October 2015 based on efficacy, complication, total score (ECT score) and related factors.MethodA historical prospective study on patients diagnosed with neurovascular compression syndrome managed by Department of Neurosurgery RSUPN Dr. Cipto Mangunkusumo, January 2011-October 2015 based on efficacy, complication, total score (ECT score). The result is compared with the original publication of ECT score outcome. Research data was obtained through medical records.ResultsTwenty one patients diagnosed with trigeminal neuralgia and 11 patients diagnosed with hemifacial spasm were treated by microvascular decompression surgery since January 2011 - October 2015. In trigeminal neuralgia group shown fifteen patients with more than one year post operative period with categorized outcome : 13 patients (87%) excellent (T-0), 1 patient (6%) good (T-1), 0 patient fair (T-2), 1 patient (6%) poor (T3-5). In hemifacial spasm group shown 11 patient with more than one year post operative period with categorized outcome : 5 patient (62,5%) excellent (T-0), 2 patient (25%) good (T-1), 0 patient fair (T-2), 1 patient (12,5%) poor (T3-5). Sample size of research were limited and related to insignificant findings of related factors. ConclusionEfficacy complication total score is efficient in evaluating post microvascular decompression surgery outcome. Trigeminal neuralgia group shown 13 of 15 patients with excellent outcome (T0). Hemifacial spasm group shown 5 of 8 patients with excellent outcome (T0)."

"ABSTRAKLatar belakang dan tujuan : Trigeminal neuralgia (TGN) atau tic douloureux adalah rasa nyeri seperti ditusuk-tusuk pada satu sisi wajah. Prevalensi TGN 0,01% sampai 0,3%, angka kejadian 3,4 sampai 5,9 per 100.000 orang pertahun. 3D CISS MRI waktu akuisisi singkat, Signal to Noise Ratio tinggi, dan Contrast to Noise Ratio yang baik. Instrumen Pain Assessment Scale (PAS) yang digunakan adalah Pain Rating Scale (PRS) karena mudah digunakan, tersedia luas dan murah. PRS dapat dipertimbangkan sebagai instrumen penilaian perkiraan jarak Neurovascular compression terhadap Root Exit Zone (REZ).Metode : Penelitian retrospektif pada 32 subjek Trigeminal Neuralgia yang melakukan pemeriksaan 3D CISS MRI dalam rentang Januari 2013 sampai Januari 2016. Evaluasi 3D CISS MRI 32 subjek ditemukan 35 origin vaskular penyebab kompresi. Metode penelitian menggunakan uji korelatif dengan pendekatan potong lintang antara nilai PRS dengan jarak NC terhadap REZ yang dievaluasi menggunakan 3D CISS MRI.Hasil : Menggunakan tes Spearman terhadap 35 subjek kompresi diperoleh hasil terdapat korelasi antara nilai PRS dengan jarak NC terhadap REZ dengan rerata jarak kompresi 2,10 mm ± 2,10 (r = -0,39 dan p= 0,021). Dihasilkan formulasi regresi jarak kompresi 3,15 ? 0,47 x Skala nyeri.Kesimpulan : Terdapat korelasi antara nilai PRS dengan jarak NCterhadap REZ pada pasien Trigeminal neuralgia.

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ABSTRACTBackground and Objective: Trigeminal neuralgia or tic douloureuxis unilateral facial pain. TGN prevalence 0,01% to 0,3%, incidence rate 3,4 to 5,9 per 100.000 people a year. High signal to noise ratio and better contrast to noise ratio is 3D CISS MR benefits. Trigeminal pain evaluated with pain assessment scale because simple, less expensive and widely available. So it can be considered as an assessment instrument to estimates neurovascular compressiondistance related to trigeminal nerve root exit zone.Methods : This is a retrospective study on 32 subjects trigeminal neuralgia who had 3D CISS MR examination within January 2013 to January 2016. Evaluation 3D CISS MR found 35 vascular origin causes compression. This methods using correlative study with cross sectional between PAS value with neurovascular compression distance related to trigeminal nerve root exit zone.Results : From 35 subject compression with Spearman test there is moderate correlation between PAS value with neurovascular compression distance related to trigeminal nerve root exit zone (Mean 2.10 mm ± 2,10, r = -0,39 and p = 0,021) and result Regretion formulation 3,15 ? 0,47 x Pain scale.Conclusion : There is moderate correlation between PRS value with neurovascular compression distance related to trigeminal nerve root exit zone."

"Latar Belakang. Meningioma memiliki jumlah kasus yang cukup banyak dan dapat mempengaruhi kualitas hidup pasien karena adanya gejala nyeri dan gangguan emosional. Karena itu, penting diketahui luaran dari hasil tindakan operasi pada pasien meningioma. Penulis menggunakan instrumen EORTC QLQ C-30 untuk menilai kualitas hidup pasien dengan meningioma sphenoorbita setelah operasi. Metode. Penelitian ini adalah studi cross sectional. Subyek adalah penderita meningioma dengan hiperostosis sphenoorbita yang dilakukan pembedahan di RSUPN Cipto Mangunkusumo periode Oktober hingga Desember 2016 sebanyak 40 orang. Data diambil dari rekam medis pasien dan kuesioner EORTC QLQ-C30 yang mencakup status kesehatan global, fungsi fisik, fungsi peran, fungsi emosional, fungsi kognitif, fungsi sosial, dan gejala-gejala klinis. Hasil. Berdasarkan perhitungan skor EORTC QLQ-C30 didapatkan adanya kenaikan yang bermakna secara statistik p-value ......Background. Meningioma has a considerable number of cases and can affect patients quality of life due to pain and emotional disturbance. Therefore, it is important to know the outcome of surgical procedures in patients with meningioma. The authors use the EORTC QLQ C 30 instrument to assess the quality of life of patients with sphenoorbital meningioma after surgery. Method. This study was a cross sectional study. The subjects were patients with meningioma with hyperostosis sphenoorbita who underwent surgery at Cipto Mangunkusumo Hospital from October to December 2016 as many as 40 people. Data were taken from the patient's medical record and the EORTC QLQ C30 questionnaire. Results. Based on the calculation of EORTC QLQ C30 score, there was a statistically significant increase p value "