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Ditemukan 18 dokumen yang sesuai dengan query
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Ari Wibisono, author
Molecular dynamic simulation is one field of science that uses computer as a resource for computational methods to calculate the number of forces acting within a molecular system and analyzing its movement. This simulation is useful for the discovery of drug compounds from an illness. This study uses Gromacs as...
ICACSIS, 2010
MK-Pdf
UI - Makalah dan Kertas Kerja  Universitas Indonesia Library
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Heru Suhartanto, author
ABSTRACT
One of the processes requiring HPC environments is Molecular Dynamics ( MD ) . In tropical countries, the MD process is very important in the preparation of virtual screening experiments for anti-malaria search. Previous works on the virtual screening project for anti-malaria search conducted by WISDOM project uses...
2014
MK-Pdf
Artikel Jurnal  Universitas Indonesia Library
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Indri Indrawan, author
As a prolactin antagonist, dopamine binds to its receptor D2 and suppresses the secretion of prolactin from the pituitary gland. Required ligand that can interact with receptor so that dopamine can no longer bound to its receptor. Ligands empirically derived from plants and have been proven to increase human lactation. In silico study...
2013
MK-Pdf
UI - Makalah dan Kertas Kerja  Universitas Indonesia Library
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Aries Fitriawan, author
ABSTRACT
Virtual screening (VS) is a computational technique used in drug discovery. Virtual Screening process usually works by identifying structures that are most likely to bind the target of drug. Virtual screening is usually based on compound similarity or database docking. Thus, the identification for drug compounds based on structure classification still...
2016
MK-Pdf
UI - Makalah dan Kertas Kerja  Universitas Indonesia Library
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Marvi Nurjanah, author
ABSTRACT
Xylitol is a five-carbon polyol sugar. It has many healthy benefits and is widely used in food, pharmaceutical, and healthcare. Natural sources with abundant carbon such as lignocellulose can be used for xylitol production. One of the potencial sources with high prevalency in Indonesia is water hyacinth. It is known...
2013
MK-Pdf
UI - Makalah dan Kertas Kerja  Universitas Indonesia Library
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Luthfiyyah Mutsnaini, author
ABSTRACT
Xylitol is five-carbon polyol sugar which widely used as a sweetener in food and pharmaceutical. Xylitol production by chemical procedures using high pressure and temperature also needed extensive purification are less cost-effective in production. Fermentation which has more advantages with lower cost due tocheaper substrate and the non-necessity of xylose purification. The purposes...
2013
MK-Pdf
UI - Makalah dan Kertas Kerja  Universitas Indonesia Library
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Sealtial Mau, author
ABSTRAK
Penggunaan energi yang effisien menjadi tantangan dunia saat ini untuk terus ditingkatkan. Berbagai metode terus dikembangkan oleh para peneliti dan ilmuan untuk mencapai apa yang diharapkan. Dalam sistem perpipaan, energi dibutuhkan untuk dapat menggerakkan fluida yang akan dialirkan. Ilmu mekanika fluida berperan penting untuk dapat mengkarakteristik  fluida saat mengalir. Secara...
2019
D2697
UI - Disertasi (Membership)  Universitas Indonesia Library
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Azminah, author

Sirtuin 1 (SIRT1) adalah famili  kelas III dari protein histon deasetilasi (HDAC) dan reaksinya bergantung  dengan  NAD+. Aktivator SIRT1 menyerupai pembatasan kalori merupakan pendekatan terapi untuk diabetes mellitus tipe 2. Pencarian obat dapat dilakukan dengan metode  in silico untuk mempercepat dan memfasilitasi identifikasi kandidat senyawa terbaik dan karakteristik fisikokimia dan...

Depok: Fakultas Farmasi Universitas Indonesia, 2020
D2810
UI - Disertasi (Membership)  Universitas Indonesia Library
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