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"Penyakit Tuberkulosis paru (TB Paru) masih menjadi penyebab tingginya angka kesakitan dan kematian di dunia, termasuk Indonesia. Angka penemuan kasus TB paru di Kota Sukabumi berada di urutan ke-3 tertinggi yang ada di Provinsi Jawa Barat, yaitu mencapai 75,83%. Tujuan penelitian ini adalah untuk menganalisis faktor risiko yang mempengaruhi kejadian TB paru di Kota Sukabumi. Desain penelitian yang digunakan adalah kasus kontrol. Kriteria kasus yang digunakan dalam penelitian ini adalah penderita baru TB Paru yang berusia minimal 15 tahun dan dinyatakan positif berdasarkan konfirmasi laboratorium Puskesmas, sudah diobati dengan OAT selama sekitar 4 minggu serta bertempat tinggal di Kota Sukabumi, sedangkan kriteria kontrolnya adalah tetangga terdekat dari rumah kasus yang tidak menderita TB paru, tidak memiliki gejala klinis mirip TB paru berdasarkan konfirmasi dari petugas puskesmas, berusia minimal 15 tahun dan bertempat tinggal di Kota Sukabumi. Jumlah sampel kasus adalah 58 responden, dan kontrol 58 responden. Hasil dalam penelitian ini menunjukkan bahwa faktor risiko yang berpengaruh terhadap kejadian TB paru di Kota Sukabumi adalah jenis kelamin (OR 7,28; 95% CI 3,161-16,782), kepadatan hunian (OR 3,24; 95% CI 1,401-7,477), pencahayaan (OR 4,06; 95% CI 1,850-8,916), keberadaan sinar matahari di dalam ruangan (OR 3,05; 95% CI 1,206-7,687), dan kebiasaan merokok (OR 7,53; 95% CI 3,227-17,564). Hasil analisis multivariat dengan menggunakaan pemodelan regresi logistik menunjukkan bahwa jenis kelamin laki-laki, dan pencahayaan rumah kurang dari 60 lux berhubungan dengan terjadinya TB paru. Faktor risiko yang paling dominan mempengaruhi kejadian TB paru di Kota Sukabumi berdasarkan analisis multivariat adalah jenis kelamin laki-laki (OR 5,85; 95% CI 2,384-13,821).

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Pulmonary Tuberculosis remains a major cause of morbidity and mortality in the world, including Indonesia. Case Detection Rate (CDR) of pulmonary tuberculosis in Sukabumi is the 3rd highest among the cities in West Java Province, as the value reaches 75.83%. The aim of this study is to analyze the risk factor that affected pulmonary tuberculosis incident in Sukabumi in 2014.

This study used a case control design, as the criteria of the case used were new pulmonary TB patients with at least 15 years old age, are sputum smear positive confirmed by the health care laboratory, has been treated with Anti-Tuberculosis Medications for about 4 weeks, and live in Sukabumi City, whereas the control criteria were nearest neighbors of the cases that neither did suffer from pulmonary tuberculosis nor have clinical symptoms similar to pulmonary tuberculosis based on the confirmation of the clinic staff, with at least 15 years old age, and live in Sukabumi City. The number of case samples and control samples were 58 respondents, respectively.

The results of this study showed that the risk factors affecting the incidence of pulmonary tuberculosis in Sukabumi were gender (OR 7.28; 95% CI 3.161-16.782), housing density (OR 3.24; 95% CI 1.401-7.477), lighting (OR 4.06; 95% CI 1.850-8.916), sunlight existence inside the house (OR 3.05; 95% CI 1.206-7.687), and smoking habit (OR 7.53; 95% CI 3.227-17.564). Multivariate analysis using multiple logistic regression model indicated that the male gender and the house lighting less than 60 lux were associated with the occurrence of pulmonary tuberculosis. The most dominant risk factor affecting the incidence of pulmonary tuberculosis in Sukabumi was male gender (OR 5.85; 95% CI 2.384-13.821)."

"Tuberkulosis paru (TB paru) adalah penyakit menular yang disebabkan oleh bakteri Mycobacterium tuberculosis. Penyakit ini menular dari satu orang ke orang lain melalui droplet yang ditransmisikan melalui udara. Tingginya angka kasus penyakit TB dapat disebabkan oleh berbagai faktor, salah satunya adalah faktor lingkungan. Penelitian ini bertujuan untuk mengetahui hubungan antara faktor kepadatan penduduk, cakupan rumah sehat, serta iklim (suhu udara, kelembaban udara, dan curah hujan) terhadap angka proporsi kasus TB paru BTA Positif di Kota Surabaya pada tahun 2015-2019. Penelitian ini menggunakan data sekunder dari Badan Pusat Statistika dan Dinas Kesehatan Kota Surabaya dengan metode studi ekologi time trend dan analisis spasial. Hasil penelitian menunjukkan bahwa terdapat hubungan signifikan antara variabel kepadatan penduduk (p = 0,000; r = 0,308), cakupan rumah sehat (p = 0,000; r = -0,363), serta kelembaban udara pada lag time 1 tahun (p = 0,014; r = 0,949) dengan proporsi TB paru BTA positif. Sementara untuk faktor suhu udara serta curah hujan menunjukkan hubungan yang tidak signfikan dengan proporsi TB paru BTA Positif. Berdasarkan peta analisis spasial, didapatkan pola yang jelas bahwa angka proporsi yang tinggi terdapat pada wilayah kecamatan yang memiliki cakupan rumah sehat yang rendah, namun pada faktor kepadatan penduduk tidak terlihat pola yang jelas. Oleh karena itu, disarankan untuk dilakukan upaya pencegahan dan pengendalian penyakit TB paru terutama pada wilayah kecamatan yang memiliki kepadatan penduduk yang tinggi dan juga melalui upaya pengembangan rumah sehat yang optimal.

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Pulmonary tuberculosis or pulmonary TB is an infectious disease caused by Mycobacterium tuberculosis. This disease is transmitted from one person to another through droplets that are transmitted through the air. The high number of TB cases can be caused by various factors, one of which is environmental factors. This study aims to determine the relationship between population density, healthy housing coverage, and climate factors (air temperature, relative humidity, and rainfall) to the proportion smear-positive pulmonary TB cases in Surabaya city in 2015-2019. This study uses secondary data from the Central Bureau of Statistics and the Surabaya City Health Office with time trend ecological study methods and spatial analysis. The results showed that there was a significant relationship between population density (p = 0.000; r = 0.308), healthy house coverage (p = 0.000; r = -0.363), and humidity at a 1 year lag time (p = 0.014; r = 0.949) with the proportion of smear-positive pulmonary TB. Meanwhile, the air temperature and rainfall factors showed a non-significant relationship with the proportion of smear-positive pulmonary TB. Based on the spatial analysis map, a clear pattern is found that the high proportion is found in sub-districts that have low coverage of healthy homes, but on the population density factor there is no clear pattern. Therefore, it is recommended to prevent and control pulmonary TB disease, especially in sub-districts that have a high population density and also through efforts to develop optimal healthy homes."

"Skripsi ini membahas terjadinya peningkatan kejadian kasus Tuberkulosis paru BTA (+) di Kota Sukabumi dan belum diketahuinya pola penyebaran penyakit Tuberkulosis paru BTA (+) dengan analisis spasial berdasarkan faktor kependudukan dan pelayanan kesehatan, bertujuan untuk mengetahui analisis spasial kejadian Tuberkulosis paru BTA (+) di Kota Sukabumi tahun 2010-2012. Penelitian menggunakan desain studi ekologi jenis multiple group dengan time trend menggunakan pendekatan analisis spasial. Hasil penelitian bahwa kasus baru dan insiden Tuberkulosis paru BTA (+) di Kota Sukabumi tahun 2010-2012 meningkat dan cenderung mengikuti pola persebaran kepadatan penduduk, jumlah fasilitas pelayanan kesehatan dan jumlah tenaga kesehatan. Dari hasil penelitian ini menyarankan agar program pemberantasan dan pengendalian penyakit Tuberkulosis paru BTA (+) sebaiknya diprioritaskan pada wilayah dengan kepadatan penduduk tinggi.

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This essay discusses the increased incidence of pulmonary Tuberculosis cases of Acid-Resistant Bacteria (+) in Sukabumi and not knowing the pattern of spread of disease pulmonary Tuberculosis Acid-Resistant Bacteria (+) with a spatial analysis based on demographic factors and health services, spatial analysis aimed to determine the incidence of pulmonary Tuberculosis Acid–Resistant Bacteria (+) Sukabumi in 2010-2012. Research design using multiple types of ecological study group with a time trend using spatial analysis approach.

The results of that study and the incidence of new cases of pulmonary Tuberculosis Acid–Resistant Bacteria (+) in Sukabumi in 2010-2012 increased and tend to follow the pattern of distribution of population density, the number of health care facilities and health workers. From the results of this study suggest that eradication programs and disease control pulmonary Tuberculosis Acid–Resistant Bacteria (+) should be prioritized in areas with high population density."

"ABSTRAKPada tahun 2010, Periode Prevalence Tuberkulosis DKI Jakarta berada diperingkat kelima se-Indonesia. Angka Penjaringan Suspek, CDR, dan AngkaKonversi Tuberkulosis di Jatinegara mengalami fluktuasi selama 2009—2012.Penelitian ini bertujuan mengetahui hubungan antara keberadaan penderitaserumah, kepadatan penghuni, ventilasi, dan fisik bangunan rumah dengankejadian tuberkulosis paru BTA Positif. Desain penelitian ini adalah kasus-kontroldengan jumlah sampel masing-masing 58 orang. Kasus adalah penderitatuberkulosis paru BTA Positif yang datang berobat ke puskesmas. Kontrol adalahpenduduk yang tidak menderita tuberkulosis dan tinggal bertetangga dengankasus. Ada hubungan bermakna antara kepadatan penghuni dalam rumah dengankejadian tuberkulosis paru BTA Positif {p=0,015; OR=2,709 (95%CI: 1,273—5,767)}.

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ABSTRACTIn 2010, Tuberculosis Period Prevalence of Jakarta ranked 5 in Indonesia. SuspectDetection Rate, CDR, and Conversion Rate of Tuberculosis in Jatinegara wasfluctuating in 2009—2012. Purpose of this research is to find the relationshipbetween relative with tuberculosis, household density, ventilation, and housebuilding condition with smear-positive pulmonary tuberculosis incidence. A casecontrolstudy is undertaken with 58 samples for each group. Case is defined as allpatients diagnosed with smear-positive pulmonary tuberculosis and treated atpublic health centre. Control is defined as persons having no history oftuberculosis and live at the same neighborhood with case group. There is asignificant relationship between household density and smear-positive pulmonarytuberculosis incidence {p=0,015; OR=02,709 (95%CI: 1,273—5,767)}."

"Tuberkulosis masih merupakan salah satu masalah kesehatan utama saat ini dan menjadi tantangan global. Ada beberapa faktor risiko yang mempermudah terjadinya tuberculosis pada anak, yaitu anak yang terpajan dengan orang dewasa dengan TB paru BTA positif terutama tinggal serumah, tinggal di daerah endemis, lingkungan yang sanitasinya tidak baik, faktor ekonomi, kondisi rumah tinggal (ukuran, kepadatan dan ventilasi rumah). Tujuan penelitian ini untuk melihat besarnya risiko kejadian sakit tuberculosis pada anak yang kontak serumah dengan penderita tuberculosis paru BTA positif. Penelitian ini menggunakan disain studi cross sectional, dilakukan pada November 2015-Maret 2016. Sampel adalah anak yang memeriksakan diri dan melakukan test tuberculin di Puskesmas kecamatan Cilandak.Untuk melihat hubungan dilakukan. Pada penelitian ini didapatkan 85 anak melakukan test tuberculin, dan dari 69 anak yang kontak serumah dengan penderita TB paru BTA positif didapatkan 8 anak (11,6%) yang positif. Sedangkan dari 16 anak yang tidak kontak serumah dengan penderita TB paru BTA positif didapatkan 1 anak (6,2%) yang hasil test tuberkulinnya positif.Ada hubungan bermakna antara kepadatan hunian dan anggota keluarga yang merokok dengan risiko kejadian tuberculosis pada anak. Kesimpulan dari penelitian ini adalah risiko kejadian tuberculosis dapat dipengaruhi karena kontak serumah dengan penderita TB paru BTA positif.

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Tuberculosis remains one of the major health problems at the moment and become a global challenge. There are several risk factors that facilitate the occurrence of tuberculosis in children, the children exposed to adults with pulmonary TB smear positive mainly stayed at home, living in endemic areas, environmental sanitation is not good, economic factors, the condition of residence (size, density and ventilation home). The purpose of this study to see the magnitude of the risk of the occurrence of illness tuberculosis in children with household contact with smear positive pulmonary tuberculosis patients. This study used cross sectional design of the study, conducted in November 2015 and March 2016. The sample is child check-ups and perform tuberculin test in Cilandak sub-district health centers. In this study, 85 children perform tuberculin test, and of the 69 children whose household contact with smear positive pulmonary tuberculosis patients found 8 children (11.6%) were positive. While the 16 children who are not household contact with smear positive pulmonary tuberculosis patients got one child (6.2%) were the result of test tuberculin is positif.There is significant relationship between population density and family members who smoke the risk of incidence of tuberculosis in children. The conclusion of this study is the risk of tuberculosis incidence may be affected due to household contact with smear positive pulmonary tuberculosis patients."

"ABSTRACTAngka penemuan kasus (Case Detection Rate) di Kota Sukabumi merupakan tertinggi ketiga di Provinsi Jawa Barat yaitu 75,83% pada tahun 2013. Penelitian ini bertujuan untuk mengetahui kualitas lingkungan rumah dengan kejadian TB Paru BTA (+) di Kota Sukabumi tahun 2014. Penelitian ini menggunakan desain studi unmatched case control. Sampel penelitian sebanyak 116 responden yang terdiri dari 58 kasus dan 58 kontrol dan tercatat dalam buku register bulan Februari-April 2014. Teknik pengambilan sampel dalam penelitian ini menggunakan purposive sampling yang sesuai dengan kriteria inklusi dan eksklusi. Data variabel independen diperoleh dengan wawancara, observasi dan mengukur.Hasil analisis bivariat menunjukkan bahwa terdapat hubungan antara pencahayaan (p-value: 0,000; OR: 4,222; 95%CI: 1,943-9,176), kepadatan rumah (p-value: 0,009; OR: 3,237; 95%CI: 1,401-7,477), jenis kelamin (p-value: 0,000; OR: 7,283; 95% CI: 3,161-16,782), status gizi (p-value: 0,000; OR: 10,667; 95% CI: 4,426-25,705) kejadian TB Paru BTA (+), sedangkan kelembaban, suhu, ventilasi, kepadatan kamar, umur dan pengetahuan tidak berhubungan dengan kejadian TB paru.

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ABSTRACTCase Detection Rate of Sukabumi City is the third highest in West Java Province 75,83% in 2013. The purpose of this study is to determine quality of home environment with the incidence of pulmonary TB BTA (+) in Sukabumi City in 2014. This study used unmatched case-control design. The sample 116 people consists of 58 cases and 58 control recorded in the register book of February-April 2014. Sampling technique in this research using purposive sampling which is appropriate with the criteria of inclusion and exclusion. All of the data and informations in this research are collected using interviews, observations and variables measurement.The result of bivariat analysis showed that there were correlation between lighting (p-value: 0,000; OR: 4,222; 95%CI: 1,943-9,176), housing density (p-value: 0,009; OR: 3,237; 95%CI: 1,401-7,477), sex (p-value: 0,000; OR: 7,283; 95% CI: 3,161-16,782), nutrition status (p-value: 0,000; OR: 10,667; 95% CI: 4,426-25,705) with the incidence of pulmonary TB. While other variables like humidity, temperature, ventilation, room density, age and knowledge have no correlation with the incidence of pulmonary TB."

"Tuberkulosis (TB) merupakan salah satu penyakit menular yang masih menjadi salah satu masalah kesehatan dan menjadi 10 besar penyebab kematian di dunia. Kota Jakarta Timur menjadi wilayah dengan jumlah kasus TB paru BTA positif terbanyak di DKI Jakarta pada tahun 2017 sebanyak 4.100 kasus. Faktor iklim, yang meliputi suhu, kelembaban dan curah hujan diketahui dapat mempengaruhi keberadaan bakteri M.tb untuk dapat hidup dengan optimum. Penelitian ini bertujuan untuk mengetahui distribusi dan korelasi faktor iklim dengan jumlah kasus TB paru BTA positif di Kota Jakarta Timur. Penelitian ini menggunakan desain studi ekologi berdasarkan waktu (time-trend study) dengan pendekatan spasial. Analisis data dilakukan dengan uji korelasi spearman dan analisis autokorelasi spasial dengan Moran’s I. Hasil penelitian menunjukkan rata-rata jumlah kasus TB paru BTA positif di Kota Jakarta Timur tahun 2009-2018 sebanyak 257,5 kasus. Ada korelasi antara rata-rata suhu udara (p=0,005, r=0,255) dan kelembaban (p=0,005, r= -0,255) dengan jumlah kasus TB paru BTA positif di Jakarta Timur tahun 2009-2018. Ada autokorelasi spasial distribusi kasus TB paru BTA positif di Kota Jakarta Timur dengan distribusi kasus yang terjadi secara random (Moran’s I= 0,014; p= 0,247). Hasil penelitian menyarankan bahwa implementasi program pencegahan dan pengendalian TB paru dapat dilakukan terutama pada bulan Februari dan Juli, sehingga dapat mengantisipasi peningkatan kasus TB paru BTA positif 3 bulan setelahnya serta diperlukan perluasan wilayah ruang terbuka hijau sehingga dapat menciptakan kenyamanan dan menurunkan suhu serta meningkatkan kelembaban relatif di sekitarnya.

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Tuberculosis (TB) is an infectious disease that still a health problem and become the top 10 cause of death in the world. East Jakarta is the region with the highest number of smear positive pulmonary TB cases in DKI Jakarta in 2017, which was 4,100 cases. Climatic factors, including temperature, humidity and rainfall can be known to influence M.tb bacteria to live optimally. This study aims to determine the distribution and correlate climatic factors with the number of smear positive pulmonary TB cases in East Jakarta. This study used a time-trend study design with a spatial approach. Data analysis was carried out by using the Spearman correlation test and spatial autocorrelation analysis with Moran's I. The results showed the average number of positive smear pulmonary TB cases in East Jakarta City 2009-2018 are 257.5 cases. There is a correlation between the average air temperature (p = 0.005, r = 0.255) and humidity (p = 0.005, r = -0.255) with the number of smear positive pulmonary TB cases in East Jakarta in 2009-2018. There was a spatial autocorrelation of the distribution of smear positive pulmonary TB cases in the City of East Jakarta with a random distribution of cases (Moran's I = 0.014; p = 0.247). The results suggest that implementation of TB prevention and control programs can be carried out, especially in the February and July to anticipate the increasing cases of smear positive pulmonary TB 3 months afterwards and an expansion of the green open space is needed so that it can create comfort and reduce temperature and increase humidity surrounding.

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"[ABSTRAKPM2,5 merupakan salah satu indikator adanya pencemaran udara dalamruang (indoor air pollution). Indonesia termasuk peringkat kelima jumlah kasus TBterbesar di dunia, dan Kota Cirebon merupakan kota dengan angka penemuan kasusTB paru tertinggi di Provinsi Jawa Barat. Tujuan penelitian ini adalah untukmenganalisis hubungan PM2,5 di udara ruang dalam rumah dengan kejadian TBparu BTA positif di Kota Cirebon.Disain penelitian ini adalah kasus kontrol. Kriteria kasus adalah penderitabaru TB Paru yang berusia minimal 15 tahun dan hasil pemeriksaan sputum positifberdasarkan konfirmasi laboratorium Puskesmas periode November 2014 s/d April2015 serta bertempat tinggal di Kota Cirebon. Kriteria kontrol adalah tetanggaterdekat kasus yang tidak menderita TB paru, tidak memiliki gejala klinis mirip TBparu berdasarkan konfirmasi dari petugas puskesmas setempat, berusia minimal 15tahun dan bertempat tinggal di Kota Cirebon. Total jumlah sampel adalah 168responden dengan jumlah kasus adalah 84 responden, dan kontrol 84 responden.Konsentrasi PM2,5 di udara ruang dalam rumah berpengaruh terhadapkejadian TB paru BTA positif di Kota Cirebon (OR 7,034; 95% CI 3,570 ? 13,860).Variabel lainnya yang signifikan adalah jenis kelamin (OR 3,947; 95% CI 2,026-7,692), lama berada di rumah (OR 2,682; 95% CI 1,430 ? 5,028), jenis bahan bakarmemasak (OR 3,260; 95% CI 1,116-9,523), status merokok (OR 3,034; 95% CI1,446 ? 6,365), jenis atap rumah (OR 3,713; 95% CI 1,945 ? 7,089), dan lajuventilasi kamar (OR 2,493; 95% CI 1,264 ? 4,918). Hasil analisis multivariatdengan regresi logistik menunjukkan bahwa konsentrasi PM2,5 dalam rumahberhubungan dengan kejadian TB paru BTA positif (OR adjusted 6,14; 95% CI2,904-12,975) dikontrol oleh variabel jenis kelamin, jenis atap rumah, dan lajuventilasi kamar. Masih banyak rumah yang belum dilengkapi jendela atauventilasinya kurang, atap rumah tidak dilengkapi oleh langit-langit, sehingga masihbanyak rumah yang tidak memenuhi kriteria rumah sehat. Diperlukan upayapeningkatan pengetahuan dan kesadaran masyarakat tentang kriteria rumah sehat,dan masyarakat agar menjaga pola perilaku hidup bersih dan sehat, termasuk tidakmerokok.

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ABSTRACTPM2,5 is one indicator of indoor air pollution. Indonesia is the fifth largestnumber of TB cases in the world, and the city of Cirebon is a city with the highestrate of pulmonary TB case detection in West Java province. The purpose of thisstudy was to analyze the relationship between PM2,5 in the indoor air and theincidence of smear-positive pulmonary TB in the city of Cirebon.The design of this study was a case-control. Cases criteria were patientswith TB minimum age 15 years old and had positive sputum test confirmed withpublic health care laboratory test from November 2014 to April 2015 and lived inCirebon City. Controls criteria were the nearest neighbor not suffering TB and hadno clinical symptomps similar to TB confirmed by the local public health centreofficials, at least 15 years old and resides in Cirebon city. The total number ofsamples is 168 respondents by the number of cases is 84 respondents, and 84control respondents.PM2,5 concentration in the indoor air affected the incidence of smearpositivepulmonary TB in Cirebon city (OR 7.034; 95% CI 3.570 to 13.860).Significant other variables are gender (OR 3.947; 95% CI 2.026 to 7.692), indoorstayperiod (OR 2.682; 95% CI 1.430 to 5.028), the type of cooking fuel (OR 3.260;95% CI 1.116 to 9.523), smoking status (OR 3.034; 95% CI 1.446 to 6.365), typesof roofs (OR 3.713; 95% CI 1.945 to 7.089), and the ventilation rate of the room(OR 2.493; 95% CI 1.264 to 4.918). Results of multivariate analysis using logisticregression modeling showed that concentrations of PM2,5 in the indoor airassociated with the incidence of pulmonary TB smear positive (OR adjusted 6,14;95% CI 2.904 - 12.975) after being controlled by the variable gender, roof type ofthe house, and the ventilation rate of the room. There are still many homes are notequipped with a window or a lack of ventilation, the roof of the house is notcompleted by the ceiling, so there is still a lot of homes that do not meet the criteriafor a healthy home. Necessary efforts to increase knowledge and awareness aboutthe criteria of a healthy home, and the community to maintain a clean and healthylifestyle, including not smoking.;PM2,5 is one indicator of indoor air pollution. Indonesia is the fifth largestnumber of TB cases in the world, and the city of Cirebon is a city with the highestrate of pulmonary TB case detection in West Java province. The purpose of thisstudy was to analyze the relationship between PM2,5 in the indoor air and theincidence of smear-positive pulmonary TB in the city of Cirebon.The design of this study was a case-control. Cases criteria were patientswith TB minimum age 15 years old and had positive sputum test confirmed withpublic health care laboratory test from November 2014 to April 2015 and lived inCirebon City. Controls criteria were the nearest neighbor not suffering TB and hadno clinical symptomps similar to TB confirmed by the local public health centreofficials, at least 15 years old and resides in Cirebon city. The total number ofsamples is 168 respondents by the number of cases is 84 respondents, and 84control respondents.PM2,5 concentration in the indoor air affected the incidence of smearpositivepulmonary TB in Cirebon city (OR 7.034; 95% CI 3.570 to 13.860).Significant other variables are gender (OR 3.947; 95% CI 2.026 to 7.692), indoorstayperiod (OR 2.682; 95% CI 1.430 to 5.028), the type of cooking fuel (OR 3.260;95% CI 1.116 to 9.523), smoking status (OR 3.034; 95% CI 1.446 to 6.365), typesof roofs (OR 3.713; 95% CI 1.945 to 7.089), and the ventilation rate of the room(OR 2.493; 95% CI 1.264 to 4.918). Results of multivariate analysis using logisticregression modeling showed that concentrations of PM2,5 in the indoor airassociated with the incidence of pulmonary TB smear positive (OR adjusted 6,14;95% CI 2.904 - 12.975) after being controlled by the variable gender, roof type ofthe house, and the ventilation rate of the room. There are still many homes are notequipped with a window or a lack of ventilation, the roof of the house is notcompleted by the ceiling, so there is still a lot of homes that do not meet the criteriafor a healthy home. Necessary efforts to increase knowledge and awareness aboutthe criteria of a healthy home, and the community to maintain a clean and healthylifestyle, including not smoking., PM2,5 is one indicator of indoor air pollution. Indonesia is the fifth largestnumber of TB cases in the world, and the city of Cirebon is a city with the highestrate of pulmonary TB case detection in West Java province. The purpose of thisstudy was to analyze the relationship between PM2,5 in the indoor air and theincidence of smear-positive pulmonary TB in the city of Cirebon.The design of this study was a case-control. Cases criteria were patientswith TB minimum age 15 years old and had positive sputum test confirmed withpublic health care laboratory test from November 2014 to April 2015 and lived inCirebon City. Controls criteria were the nearest neighbor not suffering TB and hadno clinical symptomps similar to TB confirmed by the local public health centreofficials, at least 15 years old and resides in Cirebon city. The total number ofsamples is 168 respondents by the number of cases is 84 respondents, and 84control respondents.PM2,5 concentration in the indoor air affected the incidence of smearpositivepulmonary TB in Cirebon city (OR 7.034; 95% CI 3.570 to 13.860).Significant other variables are gender (OR 3.947; 95% CI 2.026 to 7.692), indoorstayperiod (OR 2.682; 95% CI 1.430 to 5.028), the type of cooking fuel (OR 3.260;95% CI 1.116 to 9.523), smoking status (OR 3.034; 95% CI 1.446 to 6.365), typesof roofs (OR 3.713; 95% CI 1.945 to 7.089), and the ventilation rate of the room(OR 2.493; 95% CI 1.264 to 4.918). Results of multivariate analysis using logisticregression modeling showed that concentrations of PM2,5 in the indoor airassociated with the incidence of pulmonary TB smear positive (OR adjusted 6,14;95% CI 2.904 - 12.975) after being controlled by the variable gender, roof type ofthe house, and the ventilation rate of the room. There are still many homes are notequipped with a window or a lack of ventilation, the roof of the house is notcompleted by the ceiling, so there is still a lot of homes that do not meet the criteriafor a healthy home. Necessary efforts to increase knowledge and awareness aboutthe criteria of a healthy home, and the community to maintain a clean and healthylifestyle, including not smoking.]"

"Salah satu indikator program pengendalian TB secara Nasional strategi DOTS adalah angka keberhasilan pengobatan TB. Fokus utama pengendalian TB strategi DOTS adalah memutus mata rantai penularan TB oleh penderita TB paru sputum BTA positif. Berdasarkan penelitian penderita TB paru sputum BTA negatif dapat menularkan 13-20% (Tostmann A, et al, 2008). BBKPM Bandung sebagai salah satu UPK strategi DOTS pencapaian angka keberhasilan pengobatan masih dibawah target Nasional. Tujuan: mempelajari faktor yang mempengaruhi keberhasilan pengobatan pasien TB paru sputum BTA negatif dan pasien TB paru sputum BTA positif. Faktor yang mempengaruhi keberhasilan pengobatan TB antara lain faktor individu (umur, jenis kelamin, pekerjaan, kepatuhan berobat) dan obat dan penyakit (rejimen, dosis, lama pengobatan, komorbid HIV dan DM). Indikator keberhasilan pengobatan: pemeriksaan ulang sputum BTA menjadi/tetap negatif dan kenaikan berat badan. Desain penelitian: kohort retrospektif. Sampel: data pasien TB Paru yang tercatat di TB 01 tahun 2009-2011dijadikan 2 sub populasi, Pasien TB paru dengan sputum BTA negatif 292 kasus dan pasien TB paru dengan sputum BTA positif 461 kasus. Analisis: multivariabel regresi logistik. Hasil: OR keberhasilan pengobatan pasien TB paru sputum BTA negatif patuh berobat 1,4 dibandingkan tidak patuh (CI : 0,7-3,0) dan pasien TB paru sputum BTA positif patuh berobat 1,1 di bandingkan tidak patuh (CI : 0,6-2,2) setelah dikontrol umur, jenis kelamin dan pekerjaan. Saran: Meningkatkan peran PMO, dan memperhatikan faktor komorbid dalam tatalaksana pengobatan pasien TB paru.

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Succes rate of TB treatment is an important indicator of the Natinal TB control program.The main focus of TB control program DOTS strategy is to break the chain of TB transmission. Tostmann A, et al (2008) showed that through 13-20% sputum smear negative pulmonary tuberculosis patients can spread TB the bacteria. BBKPM Bandung as one of CGU DOTS strategy has lower treatment succes rate of the national targets.

Purpose: To study factors that influence the treatment succes rate of compare with both smear positve and negative pulmonary tuberculosis patients. Those are age, gender, occupation, treatment compliance (factor individu) and regimen, dose, duration of treatment, comorbid HIV and DM (drug and disease). Indicator of treatment succes are the conversion of sputum result examination and the gain weight.

Study design: a retrospective cohort study.

Samples: the pulmonary TB patient data recorded at TB 01 yeras 2009-2011. The number of TB patients with sputum smear positive are 461 and negative are 292.

Analysis: Multivariable logistic regression.

Result: OR treatment succes among sputum smear-negative pulmonary TB patients 1,4 (CI: 0,7-3,0) and among sputum smear positive pulmonary Tb patients who adhere to treatment is 1,1 (CI:0,6-2,2) after controlling for age, sex, and occupation.

Suggestion: Enhancing the role of the PMO to increase the treatment adherence rate, treat the TB patients with HIV and DM co-infection."

"Tuberkulosis paru adalah penyakit menular penyebab utama dari gangguan kesehatan yang disebabkan oleh bakteri Mycobacterium tuberculosis dan dapat disebarkan dari satu orang ke orang lain terutama melalui transmisi udara. Mycobacterium tuberculosis dapat tetap melayang di udara selama beberapa jam bergantung pada kondisi lingkungan. Berbagai faktor dapat mempengaruhi tingginya kasus tuberkulosis paru salah satunya adalah faktor lingkungan. Penelitian ini menggunakan studi ekologi yang bertujuan untuk mencari korelasi spasial antara ketinggian wilayah, kepadatan penduduk, dan cakupan rumah sehat dengan proporsi TB paru basil tahan asam (BTA) positif di Kota Semarang, Kota Ungaran dan Kota Magelang 2016-2018. Penelitian ini dilakukan di Kota Semarang, Kota Ungaran dan Kota Magelang dengan menggunakan data sekunder dari Dinas Kesehatan, Badan Pusat Statistik dan Badan Informasi Geospasial dari tahun 2016-2018. Penelitian ini dilakukan pada bulan Mei-Juni 2021. Selanjutnya untuk analsis statistik data dilakukan uji korelasi Spearman untuk uji bivariat dan analisis spasial menggunakan teknik overlay. Hasil penelitian ini menunjukkan bahwa terdapat korelasi antara variabel ketinggian wilayah dengan proporsi kasus TB paru BTA positif di Kota Semarang, Kota Ungaran dan Kota Magelang. Semakin rendah ketinggian wilayah semakin tinggi proporsi TB paru BTA positif. Hasil penelitian menunjukan terdapat korelasi kepadatan penduduk dengan proporsi TB paru BTA positif di Kota Semarang. Semakin tinggi kepadatan penduduk maka semakin tinggi proporsi TB paru BTA positif. Disarankan dengan dataran yang lebih rendah dapat lebih fokus dalam melakukan upaya preventif dan promotif TB paru kepada masyarakat melalui kegiatan penyuluhan atau media promosi kesehatan lainnya dan bagi pemerintah perlu berkomitmen serta kerja sama dengan pihak-pihak terkait dalam penanganan masalah kemiskinan dan kepadatan penduduk dalam rangka penanggulangan TB paru.

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Pulmonary tuberculosis is a major infectious disease caused by the bacterium Mycobacterium tuberculosis and can be spread from one person to another mainly through air transmission. Mycobacterium tuberculosis can remain floating in the air for several hours depending on environmental conditions. Various factors can affect the high cases of pulmonary tuberculosis, one of which is environmental factors. This study uses an ecological study that aims to find spatial correlation between area height, population density, and healthy home coverage with a positive acid-fast bacillus pulmonary tuberculosis in Semarang, Ungaran and Magelang cities 2016-2018. This study was conducted in Semarang City, Ungaran City and Magelang City using secondary data from the Health Office, Central Statistics Agency and Geospatial Information Agency from 2016-2018. The results of this study showed that there is a correlation between the variable altitude and the positive acid-fast bacillus pulmonary tuberculosis cases in Semarang, Ungaran and Magelang. The lower the altitude the higher the positive acid-fast bacillus pulmonary tuberculosis. The results showed that there is a correlation of population density with the positive acid-fast bacillus pulmonary tuberculosis in Semarang City. The higher the population density, the higher the proportion of sputum smear positive pulmonary tuberculosis. It is recommended that the lower ground can focus more on preventing and promoting pulmonary tuberculosis to the community through counseling activities or other health promotion media and for the government needs to commit and cooperate with relevant parties in handling poverty and population density issues in order to combat pulmonary TB."