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"Penyakit Paru Obstruktif Kronik (PPOK) kini telah menjadi penyebab kematian terbanyak keempat di dunia. Masih tingginya angka mortalitas pada tatalaksana PPOK mengharuskan pengembangan modalitas terapi yang terus-menerus. Penelitian ini bertujuan untuk mengetahui pengaruh terapi kombinasi akupunktur tanam benang dan medikamentosa terhadap indeks BODE pasien PPOK. Uji klinis acak tersamar ganda dengan pembanding dilakukan terhadap 48 pasien yang dialokasikan ke dalam kelompok kasus (kombinasi akupunktur tanam benang dan medikamentosa) atau kelompok kontrol (kelompok akupunktur sham dan medikamentosa). Akupunktur tanam benang dilakukan pada titik BL13 Feishu, BL43 Gaohuangshu, BL20 Pishu, BL23 Shenshu dan ST40 Fenglong sebanyak 2 kali dengan interval 15 hari. Indeks BODE sebagai keluaran primer dinilai pada hari ke-1 dan hari ke-30. Hasil penelitian menunjukkan perbedaan yang bermakna secara statistik maupun klinis antar kedua kelompok. Rerata penurunan indeks BODE 1,83 lebih rendah pada kelompok kasus dibandingkan dengan kelompok kontrol (p =0,000). Disimpulkan bahwa terapi kombinasi akupunktur tanam benang dan medikamentosa lebih efektif menurunkan Indeks BODE dibandingkan dengan medikamentosa saja.

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Chronic Obstructive Pulmonary Disease (COPD) is now becoming the fourth leading cause of death in the world. Since high level of mortality following COPD medication, continous research to improve treatment modalities keeps on progressing. This study aimed to establish the effect of acupoint-catgut embedment combined with medical treatment on BODE index of COPD patient. A double blind randomized controlled trial has been conducted on 48 patient allocated into acupoint-catgut embedment with medication group (case group) or sham acupuncture with medication group (control group). Acupoint-catgut embedment was done on BL13 Feishu, BL43 Gaohuangshu, BL20 Pishu, BL23 Shenshu and ST40 Fenglong, 2 times with interval 15 days. BODE index as primary outcome was assessed on day-1 and day-30. The result shown statistically and clinically important difference between groups. BODE index was reduced 1,83 point lower in case group (p = 0,000). By that result, acupoint-catgut embedment combined with medical treatment is concluded more effective than medical treatment solely in reducing BODE index."

"ABSTRAK Gastroesophageal reflux disease (GERD) merupakan suatu kondisi patologis yang disebabkan oleh refluks kandungan lambung ke dalam esofagus. GERD memiliki dampak yang besar terhadap penderitanya baik secara fisik, psikologik, sosial maupun ekonomi. Penurunan kualitas hidup dan produktifitas kerja sering ditemukan pada penderita GERD. Berbagai terapi farmakologis telah dikembangkan, namun belum memberikan hasil yang optimal. Hal tersebut mendorong pengembangan modalitas terapi lain, salah satunya akupunktur tanam benang. Penelitian ini bertujuan untuk mengetahui efektifitas terapi kombinasi akupunktur tanam benang dan medikamentosa terhadap gejala dan kualitas hidup penderita GERD. Uji klinis acak tersamar ganda dengan pembanding dilakukan terhadap 52 penderita GERD yang dialokasikan secara acak ke dalam kelompok kombinasi akupunktur tanam benang dan medikamentosa (kelompok perlakuan) atau kelompok akupunktur sham dan medikamentosa (kelompok kontrol). Akupunktur tanam benang dilakukan pada titik CV12 Zhongwan, ST36 Zusanli dan BL21 Weishu sebanyak 2 kali dengan interval 15 hari. Skor GERDQ, RQS dan SF-36 digunakan untuk mengukur keluaran terapi. Hasil penelitian menunjukkan bahwa penurunan skor GERDQ pada kelompok perlakan lebih besar dari kelompok kontrol (p<0,001) dan peningkatan skor RQS serta peningkatan skor seluruh komponen SF-36 pada kelompok perlakuan lebih besar dibanding kelompok kontrol (p<0,001). Kesimpulan penelitian adalah terapi kombinasi akupunktur tanam benang dan medikamentosa lebih efektif dalam mengurangi gejala dan meningkatkan kualitas hidup penderita GERD dibandingkan dengan terapi medikamentosa saja ABSTRACT Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients.;Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients.;Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients.;Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients.;Gastroesophageal reflux disease (GERD) is a pathological condition caused by reflux of gastric contents into the esophagus. It has been shown that GERD has significant impact on patients either physically, psychologically, socially or economically. Impaired of quality of life and working productivity are common in GERD patients. Various pharmacological therapies have been developed, but not yet provide optimal results. It encourages the development of other therapeutic modalities, such as acupoint catgut embedment. The aim of this study was to establish the effect of acupoint catgut embedment combine with medical treatment on symptom and quality of life of GERD patients. A double-blind randomized controlled trial involved 52 GERD patients randomly allocated into catgut embedding therapy with medication group (treatment group) or medication only group (control group). Catgut embedding therapy was given 2 times at CV12 Zhongwan, ST36 Zusanli and BL21 Weishu every 15 days. GERDQ, RQS and SF-36 were used to measure the primary outcomes. The result shown, the decreased of GERDQ scores at treatments group significant higher than control groups (p<0,001), the increased of RQS score and all of SF-36 components scores at treatment group significant higher than control group (p<0,001). The result suggested that acupoint-catgut embedment combined with medical treatment is more effective than medical treatment in alleviating symptoms and enhancing the quality of life of GERD patients."

"Latar Belakang: Penyakit refluks gastroesofageal GERD adalah suatu kondisi patologis akibat refluks isi lambung ke dalam esofagus. GERD merupakan penyakit yang ditimbulkan oleh berbagai faktor dengan prevalensi yang semakin meningkat di seluruh dunia. Interleukin 6 IL-6 adalah sitokin pro inflamasi ditemukan pada mukosa esofagus pasien GERD dan berkaitan dengan gangguan motorik otot esofagus. Akupunktur tanam benang telah lama dikenal sebagai salah satu terapi tambahan dalam menangani GERD. Penelitian ini bertujuan untuk mengetahui pengaruh terapi kombinasi akupunktur tanam benang dan medikamentosa terhadap kadar IL-6 serum pasien penyakit refluks gastroesofageal.Metode: Uji klinis acak tersamar tunggal dilakukan pada 40 pasien GERD yang dialokasikan ke dalam kelompok akupunktur tanam benang dan medikamentosa atau kelompok akupunktur sham dan medikamentosa. Akupunktur tanam benang dilakukan pada titik CV12 Zhongwan, ST36 Zusanli, BL21 Weishu sebanyak 2 kali dengan interval 15 hari. Kadar IL-6 dalam plasma darah secara ELISA digunakan untuk mengukur keluaran penelitian.Hasil penelitian: Tidak ada perbedaan signifikan pada kadar IL-6 sebelum terapi di kedua grup. Pada akhir terapi didapatkan penurunan kadar IL-6 pada kelompok akupunktur tanam benang dan penurunan kadar IL-6 pada kelompok sham, namun secara statistik tidak ada perbedaan bermakna antara kedua kelompok p = 0.14.Kesimpulan: Akupunktur tanam benang belum terbukti secara statistik mempengaruhi kadar IL-6 pada pasien GERD. Kata kunci : GERD, akupunktur tanam benang, IL-6.

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Backgrounds: Gastroesophageal reflux disease GERD is a pathological condition due to reflux of stomach contents into the esophagus. GERD is multifactorial disorder with increase in prevalence worldwide. Interleukin 6 IL 6 is a pro inflammatory cytokine that is commonly found in esophageal mucosa of GERD patients and associated with esophageal motor disorders. Acupoint catgut embedment has long been known as an adjunctive therapy for GERD. This study aimed to establish the effect of acupoint catgut embedment combined with medication on IL 6 serum levels of patients with GERD.

Methods: A single blind, randomized controlled trial involved 40 GERD patients randomly allocated to catgut embedding therapy plus medication or sham acupuncture with medication. Catgut embedding therapy was given two times at CV12 Zhongwan, ST36 Zusanli, BL21 Weishu every 15 days. Serum levels of IL 6 were measured by ELISA as research output.

Results: There were no significant differences in the baseline levels of pro inflammatory IL 6 mediators between groups. After one month treatment, the median levels of IL 6 were statistically insignificant decreased in catgut embedding therapy plus medication vs sham acupuncture and medication p 0.14.

Conclusion: The results suggest that catgut embedding therapy has not been proven statistically influencing the levels of IL 6 in patients with GERD. Keywords GERD, catgut embedding therapy, IL 6."

"[Prevalensi asma di Indonesia cukup tinggi (4,5%) dan beban yang diakibatkannya menyebabkan konsekuensi sosial ekonomi. Peningkatan risiko terjadinya efek samping yang mengiringi pengobatan jangka lama pada asma mendorong pengembangan modalitas terapi lain salah satunya adalah akupunktur tetapi belum ada penelitian akupunktur pada asma yang menilai efeknya pada derajat keterkontrolan asma menggunakan alat ukur yang valid. Penelitian ini bertujuan mengetahui efektivitas terapi kombinasi akupunktur tanam benang dan medikamentosa terhadap derajat keterkontrolan asma menggunakan skor ACT, pengaruhnya terhadap perubahan faal paru dan efek samping yang dapat timbul pada tindakan akupunktur tanam benang pada pasien asma bronkial derajat persisten sedang yang terkontrol sebagian dan tidak terkontrol. Uji klinis acak dan tersamar ganda dengan pembanding dilakukan pada 52 penderita asma bronkial derajat persisten sedang yang terkontrol sebagian dan tidak terkontrol yang dialokasikan secara acak menjadi kelompok terapi kombinasi akupunktur tanam benang dan medikamentosa (kelompok kasus) atau kelompok terapi medikamentosa (kelompok kontrol). Hasil penelitian menunjukkan perbedaan bermakna perubahan skor ACT dan persentasi perubahan nilai APE sebelum dan sesudah perlakuan lebih tinggi pada kelompok kasus dibanding kelompok kontrol (p < 0,05). Persentasi perubahan nilai VEP1, KVP dan VEP1/KVP sebelum dan sesudah perlakuan lebih tinggi pada kelompok kasus dibanding kelompok kontrol namun perbedaan tersebut tidak bermakna secara statistik (p > 0,05). Kesimpulan penelitian adalah terapi kombinasi akupunktur tanam benang dan medikamentosa lebih efektif dibanding terapi medikamentosa saja dalam meningkatkan derajat keterkontrolan asma pada pasien asma bronkial derajat persisten sedang yang terkontrol sebagian dan tidak terkontrol.;Asthma prevalence in Indonesia is quite high (4,5%) and the resulting burden caused socio-economic consequences. An increased risk of side effects that accompany long term treatment of asthma encourage the development of other therapeutic modalities one of which is acupoint catgut embedment but there is no studies of acupuncture in asthma that assess its effect on the degree of asthma control using a valid measurement tools. The aim of this study was to establish the effectiveness of acupoint catgut embedment combined with medical treatment on asthma control using Asthma Control Test (ACT), to establish its effect on measurement result of lung function and to monitor the side effects that may occur. This study is a randomized, double-blind and controlled clinical trial involving 52 patients with partially controlled and uncontrolled moderate persistent bronchial asthma that are allocated into groups of catgut embedding method combined with medication (case group) and group of medication (control group). The results showed a statistically significant difference in the change of ACT scores and PEF before and after treatment higher in case group compared to control group (p < 0,05). The change of FEV1, FVC and FEV1/FVC before and after treatment were higher in case group compared to control group but the differences were not statistically significant (p > 0,05). The conclucion of this study is acupoint catgut embedment combined with medical treatment is more effective than medication treatment alone in improving asthma control in patients with partially controlled and uncontrolled moderate persistent bronchial asthma., Asthma prevalence in Indonesia is quite high (4,5%) and the resulting burden caused socio-economic consequences. An increased risk of side effects that accompany long term treatment of asthma encourage the development of other therapeutic modalities one of which is acupoint catgut embedment but there is no studies of acupuncture in asthma that assess its effect on the degree of asthma control using a valid measurement tools. The aim of this study was to establish the effectiveness of acupoint catgut embedment combined with medical treatment on asthma control using Asthma Control Test (ACT), to establish its effect on measurement result of lung function and to monitor the side effects that may occur. This study is a randomized, double-blind and controlled clinical trial involving 52 patients with partially controlled and uncontrolled moderate persistent bronchial asthma that are allocated into groups of catgut embedding method combined with medication (case group) and group of medication (control group). The results showed a statistically significant difference in the change of ACT scores and PEF before and after treatment higher in case group compared to control group (p < 0,05). The change of FEV1, FVC and FEV1/FVC before and after treatment were higher in case group compared to control group but the differences were not statistically significant (p > 0,05). The conclucion of this study is acupoint catgut embedment combined with medical treatment is more effective than medication treatment alone in improving asthma control in patients with partially controlled and uncontrolled moderate persistent bronchial asthma.]"

"Obesitas merupakan suatu keadaan dengan akumulasi lemak yang tidak normal atau berlebihan di jaringan adiposa sehingga dapat mengganggu kesehatan. Diperkirakan lebih dari 500 juta orang dewasa di seluruh dunia mengalami obesitas dan 1,5 miliar mengalami masalah kelebihan berat badan. Pada obesitas terdapat peningkatan jaringan adiposa dimana jaringan adiposa dapat mensintesis dan mensekresi sitokin pro-inflamasi seperti interleukin-6 (IL-6). Akupunktur telah lama dikenal sebagai salah satu terapi tambahan dalam menangani obesitas. Akupunktur dapat menurunkan respon inflamasi pada jaringan adiposa dengan menurunkan infiltrasi makrofag ke dalam jaringan adiposa pada obesitas sehingga jumlah makrofag yang merupakan sumber produksi adipokin pro-inflamasi menjadi lebih sedikit. Penelitian ini bertujuan untuk mengetahui pengaruh terapi akupunktur tanam benang catgut dan intervensi diet terhadap perubahan kadar IL-6 dan indeks massa tubuh pada pasien obesitas. Uji klinis acak tersamar ganda dilakukan pada 36 pasien obesitas yang dialokasikan ke dalam kelompok akupunktur tanam benang catgut dan intervensi diet atau kelompok akupunktur tanam benang sham dan intervensi diet. Akupunktur tanam benang dilakukan 2 kali pada titik CV12 Zhongwan, ST25 Tianshu, CV6 Qihai, dan SP6 Sanyinjiao setiap 2 minggu. Kadar IL-6 dalam plasma darah dan indeks massa tubuh digunakan untuk mengukur keluaran penelitian. Hasil penelitian menunjukkan perbedaan bermakna rerata kadar IL-6 awal dengan akhir dalam kelompok akupunktur tanam benang catgut (p = 0.01; 95% IK: 0.03 sampai 0.23) dan rerata selisih IMT lebih rendah 0.33 pada kelompok akupunktur tanam benang catgut dibandingkan dengan kelompok akupunktur tanam benang sham (p = 0.02; 95% IK: 0.05 sampai 0.61). Kesimpulan penelitian adalah terapi kombinasi akupunktur tanam benang catgut dan intervensi diet lebih efektif dalam menurunkan kadar IL-6 dan indeks massa tubuh pada pasien obesitas.

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Obesity is a condition with abnormal fat accumulation or excessive adipose tissue so it can disturb our health. It is estimated that over 500 million adults worldwide are obese and 1.5 billion are having problems with overweight. In obese there is an increased adipose tissue which can synthesize and secrete pro-inflammatory cytokines such as interleukine-6 (IL-6). Acupuncture has long been known as an adjunctive therapy for obesity. Acupuncture can reduce inflammatory responses in adipose tissue by reducing macrophage infiltration into adipose tissue in obesity so that the number of macrophages, which are the source of production of pro-inflammatory adipokines become fewer. A double blind randomized controlled trial involved 36 obesity patients randomly allocated into catgut embedding acupuncture group with diet intervention or sham embedding acupuncture group with diet intervention. Catgut embedding therapy was given two times at CV12 Zhongwan, ST25 Tianshu, CV6 Qihai, and SP6 Sanyinjiao every two weeks. Interleukine-6 level in blood plasma and body mass index (BMI) is used to measure research output. There was a statistically significant difference within catgut embedding group with levels of IL-6 (p = 0.01; 95% CI: 0.03 to 0.23) and lower mean BMI difference of 12.33 in catgut embedding group compared with sham embedding group (p = 0.02; 95% CI: 0.05 to 0.61). The result suggest that acupoint-catgut embedding therapy combined with diet intervention is more effective in reducing IL-6 levels and BMI in obese patients."

"[ABSTRAKUremik pruritus masih menjadi masalah dan mengurangi kualitas hidup pada pasien hemodialisis, meskipun telah banyak kemajuan dalam teknik dialisis, serta terapi yang ada belum memberikan hasil yang maksimal. Terapi akupunktur dapat dikembangkan sebagai terapi pendamping pada terapi hemodialisis untuk mengurangi gejala uremik pruritus. Penelitiasn ini merupakan penelitian akupunktur pertama di Indonesia dengan subyek pasien hemodialisis. Tiga puluh tujuh pasien hemodialisis dengan uremik pruritus dibagi dalam dua kelompok secara acak, kelompok akupunktur (n=18) mendapat terapi akupunktur pada titik tunggal LI11 Quchi, sementara kelompok kontrol (n=19) mengunakan jarum plasebo The Park Sham Device. Terapi akupunktur dilakukan saat hemodialisis, seminggu dua kali sebanyak 12 kali. Skor pruritus dinilai menggunakan kuesioner pruritus 5D sebelum terapi, setelah terapi ke-4, ke-8 dan setelah terapi ke-12, serta penilaian lanjutan 4 dan 8 minggu setelah terapi selesai. Perbedaan bermakna skor pruritus 5D antara kelompok akupunktur dan kelompok kontrol terjadi setelah akhir terapi akupunktur (7,89±0,832 vs 10,63±3,166; p=0,003) dan penilaian lanjutan 4 minggu setelah terapi selesai(8,06±1,830 vs 10,95±3,341; p=0,001). Terapi akupunktur efektif menurunkan skor uremik pruritus pada pasien hemodialisis yang menjalani dialisis seminggu dua kali.

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ABSTRACTUremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week.;Uremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week., Uremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week.]"

"ABSTRAK Detrusor underactivity DU adalah berkurangnya kekuatan dan/atau durasi kontraksi yang mengakibatkan pengosongan kandung kemih yang memanjang atau inkomplit. Sebanyak enam pasien dengan diagnosis DU diinklusikan dalam penelitian ini. Akupunktur tanam benang dilakukan dengan menggunakan polydioxanone PDO yang ditusukkan di titik akupunktur BL33 dan CV3 dengan teknik penetrating needling. Akupunktur tanam benang dilakukan sebanyak satu kali. Transcutaneous tibial nerve stimulation TTNS dilakukan sebanyak 3 kali seminggu selama 4 minggu. Hasilnya penelitian menunjukkan tidak terdapat perbedaan bermakna antara rerata volume berkemih sebelum 72,00 70,48 dan setelah 158,17 139,58 akupunktur tanam benang dan TTNS, p = 0,115, namun didapatkan peningkatan dengan rerata 86,17 110,80. Tidak terdapat perbedaan bermakna antara nilai PVR sebelum 164,00 173,69 dan setelah 74,83 126,28 terapi, p = 0,151, namun didapatkan penurunan sebesar 89,17 129,07. Tidak terdapat perbedaan bermakna antara rerata Qmax sebelum 4,12 3,28 dan setelah 12,35 9,20 , p = 0,085, namun didapatkan peningkatan sebesar 8,23 9,41. Terdapat perbedaan bermakna antara skor kualitas hidup sebelum dan setelah terapi dengan p = 0,017. Kesimpulan : akupunktur tanam benang dan TTNS dapat meningkatkan volume berkemih, menurunkan PVR, dan meningkatkan Qmax penderita DU, dan dapat memperbaiki kualitas hidup penderita DU secara signifikan. ABSTRACT Detrusor underactivity DU is a contraction of reduced strength and/or duration resulting in prolonged and/or incomplete bladder emptying. A total of six DU patients were included in this research. We did thread-embedding acupuncture by inserting polydioxanone PDO into BL33 and CV3 acupuncture points with penetrating needling techniques. Thread-embedding acupuncture was given once. Transcutaneous tibial nerve stimulation TTNS was given 3 times in a week during 4 weeks. The results showed no significant differences between before and after treatment on voided volume 72,00 70,48 and 158,17 139,58 , p = 0,115, but there was improvement with mean 86,17 110,80. There was no significant difference between before and after treatment on PVR 164,00 173,69 and 74,83 126,28 , p = 0,151, but there was improvement with mean 89,17 129,07. There was no significant difference between before and after treatment on Qmax 4,12 3,28 and 12,35 9,20 , p = 0,085, but there was improvement with mean 8,23 9,41. There was significant difference between before and after treatment on quality of life scoring with p = 0,017. Conclusion : thread embedding acupuncture and TTNS increase voided volume, and Qmax, decrease PVR, improve quality of life in in detrusor underactivity patients significantly "

"Luka bakar didefinisikan sebagai kerusakan jaringan yang terjadi akibat aksi panas baik secara langsung maupun tidak langsung. Meskipun telah banyak kemajuan yang dibuat dalam terapi luka bakar, namun penyembuhan luka yang lambat masih menjadi tantangan dalam perawatan luka bakar. Akupunktur manual dapat mempercepat penyembuhan luka bakar melalui efek anti-inflamasi, meningkatkan re-epitelisasi dan angiogenesis. Sedangkan laser akupunktur merupakan terapi yang menggunakan laser enersi rendah untuk merangsang titik akupunktur. Penelitian ini menilai pengaruh akupunktur manual dan laser akupunktur terhadap kecepatan penyembuhan luka bakar yang diamati secara makroskopik dan mikroskopik. Tiga puluh enam tikus Wistar jantan dibagi secara acak kedalam kelompok kontrol (n=12), kelompok akupunktur manual (n=12), dan kelompok laser akupunktur (n=12). Setelah dilakukan induksi luka bakar, pengukuran luka dan perlakuan diberikan setiap dua hari sekali selama 14 hari. Separuh jumlah dari setiap kelompok diterminasi pada hari ke-7 dan separuh sisanya diterminasi pada hari ke-14 untuk dilakukan pengamatan mikroskopik. Pada pengukuran penutupan luas luka hari ke-14, didapatkan perbedaan bermakna (p=0,009) antara kelompok akupunktur manual (66,96 ± 9,17) dibandingkan kelompok kontrol (49,93 ± 9,15), dan perbedaan yang bermakna (p=0,009) antara kelompok laser akupunktur (72,48 ± 14,62) dibandingkan kelompok kontrol. Namun tidak didapatkan perbedaan bermakna (p=0,451) antara kelompok akupunktur manual dan laser akupunktur. Pada penilaian skoring mikroskopik hari ke-14 didapatkan perbedaan yang bermakna (p<0,001) antara kelompok akupunktur manual (16,17 ± 1,17) dibandingkan kelompok kontrol (10,33 ± 1,21), dan perbedaan yang bermakna (p=0,004) antara kelompok laser akupunktur (17,83 ± 1,47) dibandingkan kelompok kontrol. Namun tidak didapatkan perbedaan bermakna (p=0,058) antara kelompok akupunktur manual dan laser akupunktur. Hasil penelitian menunjukkan bahwa baik terapi akupunktur manual ataupun laser akupunktur dapat digunakan sebagai terapi tambahan untuk mempercepat penyembuhan luka bakar.

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Burns are defined as tissue damage that occurs as a result of the direct or indirect action of heat. Although many advanced treatments have been made in burn therapy, slow wound healing remains a challenge in burn treatment. Acupuncture can accelerate burn healing through its anti-inflammatory effect, increasing re-epithelialization and angiogenesis. While laser acupuncture is a therapy that uses low energy lasers to stimulate acupuncture points. This study assessed the effect of manual acupuncture and laser acupuncture on the speed of wound healing which were observed macroscopically and microscopically. Thirty-six male Wistar rats were randomly divided into control group (n=12), acupuncture group (n=12), and laser acupuncture group (n=12). After burn induction, wound measurements and treatments were given every two days for 14 days. Half of the numbers from each group were terminated on the 7th day and the remaining half were terminated on the 14th day for microscopic observation. On the 14th day of measurement of wound closure, there was a significant difference (p=0.009) between the acupuncture group (66.96 ± 9.17) compared to the control group (49.93 ± 9.15), and a significant difference (p =0.009) between laser acupuncture group (72.48 ± 14.62) compared to control group. However, there was no significant difference (p=0.451) between acupuncture and laser acupuncture groups. On the 14th day of microscopic scoring, there was a significant difference (p<0.001) between the acupuncture group (16.17 ± 1.17) compared to the control group (10.33 ± 1.21), and a significant difference (p = 0.004) between the laser acupuncture group (17.83 ± 1.47) versus the control group. However, there was no significant difference (p=0.058) between acupuncture and laser acupuncture groups. The results showed that either acupuncture therapy or laser acupuncture could be used as an adjunct therapy to accelerate burn healing."

"Fisik yang tidak aktif menempati peringkat keempat dalam daftar faktor risiko kematian. Bukti ilmiah semakin banyak mendukung bahwa dengan menjadikan latihan fisik sebagai bagian dari gaya hidup, dapat menurunkan risiko terjadinya berbagai penyakit. Namun, kelelahan otot dan nyeri otot juga banyak dirasakan oleh orang tidak terlatih yang baru memulai latihan. Penumpukan asam laktat di dalam otot sering dihubungkan dengan terjadinya kelelahan otot dan nyeri otot ini, yang akan memengaruhi kenyamanan melakukan latihan fisik. Saat ini, belum ada obat – obatan ataupun intervensi yang direkomendasikan secara resmi untuk menunda munculnya kelelahan otot atau nyeri otot. Penelitian ini menilai pengaruh akupunktur manual terhadap kenyamanan melakukan latihan fisik yang dievaluasi dengan menilai rerata kadar asam laktat, denyut nadi, tekanan darah sistolik dan diastolik, skala Borg untuk menilai tingkat kelelahan, serta Visual Analogue Scale (VAS) untuk menilai nyeri otot. Dua puluh enam pasien dibagi secara acak menjadi dua, kelompok akupunktur manual (n=13) dan akupunktur sham (n=13). Kedua kelompok menerima seri akupunktur yang sama, sebanyak 12 sesi dengan jarak 1 – 3 hari. Kedua kelompok juga melakukan latihan fisik yang sama, yaitu treadmill dengan intensitas sedang selama sepuluh menit, sebelum dan setelah seri terapi akupunktur. Penilaian rerata kadar asam laktat, denyut nadi, tekanan darah, skala Borg, dan VAS dilakukan dua kali, yaitu setelah latihan fisik sebelum memulai terapi pertama dan setelah latihan fisik setelah terapi terakhir. Hasil menunjukkan terdapat perbedaan bermakna pada rerata kadar asam laktat, denyut nadi, tekanan darah sistolik, tekanan darah diastolik, skala Borg, dan VAS pada kelompok akupunktur manual dibandingkan akupunktur sham. Rerata kadar asam laktat setelah terapi akupunktur 12 kali (p = 0,041). Rerata denyut nadi setelah terapi akupunktur 12 kali (p = 0,042). Rerata tekanan darah sistolik setelah terapi akupunktur 12 kali  (p = 0,024). Rerata tekanan darah diastolik setelah terapi akupunktur 12 kali (p = 0,035). Skala Borg setelah terapi akupunktur 12 kali (p = 0,043). VAS setelah terapi akupunktur 12 kali (p = 0,049). Penemuan ini menunjukkan bahwa terapi akupunktur manual memberikan pengaruh yang lebih baik terhadap kenyamanan melakukan latihan fisik.

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Physical inactivity ranks fourth in the list of risk factors for death. Scientific evidence increasingly supports that by making physical exercise a part of lifestyle, it can reduce the risk of various diseases. However, muscle fatigue and muscle aches are also felt by many untrained people who are just starting training. The buildup of lactic acid in the muscles is often associated with the occurrence of muscle fatigue and muscle pain, which will affect the comfort of doing physical exercise. At present, there are no drugs or officially recommended interventions to delay the appearance of muscle fatigue or muscle aches. This study assessed the effect of manual acupuncture on the comfort of physical exercise which was evaluated by assessing the mean levels of lactic acid, pulse, systolic and diastolic blood pressure, the Borg scale to assess the level of fatigue, and the Visual Analogue Scale (VAS) to assess muscle pain. Twenty-six patients were randomly divided into two groups, manual acupuncture (n = 13) and sham acupuncture (n = 13). Both groups received the same series of acupuncture, with 12 sessions spaced 1-3 days. Both groups also did the same physical exercise, which was a treadmill with moderate intensity for ten minutes, before and after the acupuncture therapy series. The average assessment of lactic acid levels, pulse rate, blood pressure, the Borg scale, and VAS was carried out twice, namely after physical exercise before starting the first therapy and after physical exercise after the last therapy. The results showed that there were significant differences in the average levels of lactic acid, pulse, systolic blood pressure, diastolic blood pressure, Borg scale, and VAS in the manual acupuncture group compared to sham acupuncture. Average lactic acid levels after acupuncture therapy 12 times (p = 0.041). Mean pulse rate after acupuncture therapy 12 times (p = 0.042). The mean systolic blood pressure after acupuncture therapy was 12 times (p = 0.024). Average diastolic blood pressure after acupuncture therapy 12 times (p = 0.035). Borg scale after acupuncture therapy 12 times (p = 0.043). VAS after acupuncture therapy 12 times (p = 0.049). These findings indicate that manual acupuncture therapy has a better effect on the comfort of physical exercise."

"ABSTRAKLatar belakang:Migren adalah serangan nyeri kepala primer, bersifat spesifik,paroksismal, dengan atau tanpa aura, dengan manifestasi subjektif baik sebelummaupun sesudah serangan, merupakan nyeri kepala tipe kronik dengan gejala rekurensi,menyerang usia produktif dan dapat menyebabkan penurunan produktivitas kerja hingga80%, sehingga akan mempengaruhi kualitas hidup dan kehidupan perekonomian danpendidikan secara global yang mengarah kepada kerugian bagi penderita migren daninstitusi tempat penderita migren bersekolah ,bekerja serta dalam kehidupan keluargapenderita. Dengan tingginya angka prevalensi dan disabilitas pada penderita migren,dilain pihak sampai saat ini pengobatan yang tepat terhadap migren belum didapatkansecara maksimal maka diperlukan pendalaman dalam pengobatan maupun pencegahanmigren sangat dibutuhkan., dan sampai saat ini belum didapatkan obat yang pasti, baikterhadap pencegahan dan pengobatan, sehingga perlu dikembangkan terapi yang dapatmemberikan pertolongan yang lebih akurat pada penderita migrenTujuan penelitian ini adalah menilai keberhasilan dalam penatalaksanaan migren dalammengurangi frekuensi serangan, mengurangi intensitas serangan dan mengurangi durasiserangan dari minggu ke-0,ke-4 hingga ke-8. Metode: Uji klinis acak tersamar tunggaldengan kontrol dilakukan terhadap 34 subjek dengan migren yang dialokasikan secaraacak kedalam kelompok manual akupunktur (n=17), serta kelompok medikamentosa(n=17). Penilaian menilai frekuensi, durasi dan intensitas serangan migren yang dinilaipada saat sebelum perlakuan, minggu ke-4 dan minggu ke-8 dari baseline. Hasil: Hasilpenelitian menunjukkan terdapat perbedaan bermakna antara kedua kelompok padarerata jumlah frekuensi (p=0,040), durasi (p=0,012) dan intensitas (p=0,003) seranganmigren pada minggu ke-4 dibandingkan dengan medikamentosa. Serata terdapatperbedaan yang bermakna antara kedua kelompok pada rerata jumlah jumlah frekuensi(p=0,029), durasi (p=0,001) dan intensitas (p<0,001) serangan migren pada minggu ke-8. Kesimpulan: Intervensi akupunktur manual dapat menurunkan frekuensi, durasi danintensitas serangan migren lebih baik dibandingkan dengan preventif farmakologi asamvalproat pada minggu ke-4 dan minggu ke-8.

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ABSTARCTMigraine is a primary headache attack, specific, paroxysmal, with or without aura, with subjective manifestations both before and after the attack, a chronictype of headache with symptoms of recurrence, attacks at productive age and can cause a decrease in work productivity up to 80%, so that it will affect the quality of life, economic life and education globally which leads to losses for migraine sufferers andinstitutions where migraine sufferers attend school, work and in the lives of sufferersfamilies. With the high prevalence and disability rates for migraine sufferers, on theother hand, the right treatment for migraine has not yet been obtained to the maximum,it is necessary to deepen the treatment and prevention of migraine is needed, and untilnow there has been no definitive cure, both for prevention and treatment, so it isnecessary to develop therapies that can provide more accurate relief for migrainesufferers. The purpose of this study is to assess the success in managing migraine inreducing the frequency of attacks, reducing the intensity of attacks and reducing theduration of attacks from weeks 0, 4 to 8. Methods: A randomized controlled trial withcontrol was conducted on 34 subjects with migraine who were randomly allocated intothe manual group of acupuncture (n = 17), as well as the medicine group (n = 17). Theassessment of frequency, duration and intensity of migraine attacks assessed at the timebefore treatment, at the fourth and eight week from baseline. Results: The resultsshowed there were significant differences between the two groups in the mean numberof frequencies (p = 0.040), duration (p = 0.012) and intensity (p = 0.003) of migraineattacks at the fourth week. There were significant differences between the two groups inthe average number of frequencies (p= 0.029), duration (p=0.001) and intensity(p<0.001) of migraine attacks at the eight week. Conclusion: Manual acupunctureinterventions can reduce the frequency, duration and intensity of migraine attacksbetter than the use of valproic acid in the fourth and eight week."