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"Infeksi HIV menghasilkan radikal bebas yang merusak sel dan berbagai organ tubuh. Antioksidan berperan penting untuk mengatasi kerusakan akibat radikal bebas. Penelitian dengan desain potong lintang ini merupakan bagian dari penelitian bersama untuk mengetahui korelasi kadar antioksidan (beta karoten, vitamin C, E dan seng) dengan kadar SOD pada penderita HIV/AIDS di Pokdisus AIDS FKUI/RSUPNCM, Jakarta. Pengumpulan data dilakukan sejak akhir bulan Februari 2013 sampai Maret 2013 dengan metode consecutive sampling, didapatkan 52 orang subyek memenuhi kriteria penelitian. Hasil penelitian menunjukkan median usia subyek 33 (24-40) tahun dengan 51,9% laki-laki. Sebanyak 94,2% subyek mendapatkan terapi anti retrovirus. Nilai median jumlah limfosit T CD4+ adalah 245 (50-861) sel/µL dan 63,5% subyek berada pada kelompok CDC II. Status gizi 84,6% subyek normal dan lebih dengan nilai median 21,4 (14,4-32,4) kg/m2. Nilai rerata asupan energi subyek 1850,8±454,6 kkal/hari, 76,9% subyek memiliki asupan energi kurang dari kebutuhan total harian. Nilai Median asupan lemak subyek 51,4 (22-129,4) gram/hari dan 63,5% subyek memiliki asupan lemak kurang dari energi total. Semua subyek memiliki asupan serat yang kurang dari angka kecukupan serat, nilai rerata asupan serat subyek adalah 8,6±3,6 gram. Nilai rerata asupan beta karoten subyek 10,92±4,37 mg/hari, 88,5% memiliki asupan beta karoten cukup. Nilai median kadar beta karoten subyek 0,21 (0,01-0,72) µmol/L dan 76,9% subyek memiliki kadar beta karoten rendah. Rerata kadar SOD subyek sebesar 1542,1±281 U/gHb dan 53,8% subyek memiliki kadar SOD normal. Tidak didapatkan korelasi bermakna antara kadar beta karoten dengan SOD pada penderita HIV/AIDS (r=-0,174, p=0,217).

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Free radicals formed on the course of HIV infection can cause cellular and multiple organ damage. Antioxidants play an important role to minimize damage caused by these free radicals. This research is done using cross sectional design and is part of a joint study to assess the correlation between antioxidants (beta-carotene, vitamin C, E, and zinc) and SOD levels in HIV/AIDS patients at Pokdisus AIDS FKUI/RSUPNCM, Jakarta. The study is done from late February 2013 to March 2013 using consecutive sampling method, 52 subjects matched the study’s criteria. Study shows the age median value is 33 (24-40) years old, with 51.9% male. As much as 94.2% subjects were receiving anti retroviral therapy. Median value of CD4+ T lymphocyte count is 245 (50-861) cell/µL, 63.5% subjects belong in the CDC II category. Nutritional status for 84.6% subjects was normal and overweight with median value of 21.4 (14.4-32.4) kg/m2. Mean score for energy intake is 1850.8±454.6 kcal/day and as much as 76.9% subjects have energy intake less than total daily requirement. Median value of fat intake is 51.4 (22-129.4) grams/day and 63.5% subjects have fat intake less than total energy. All subjects were found to have fiber intake less than individual fiber requirement with mean score of 8.6±3.6 grams. Subjects’ mean score for beta-carotene is 10.92±4.37 mg/day and 88.5% of the subjects have adequate beta-carotene intake. Median value of beta-carotene level is 0.21 (0.01-0.72) µmol/L and 76.9% subjects have low beta-carotene level. SOD level mean score is 1542.1±281 U/gHb, 53.8% subjects had normal SOD level. This study found no significant correlation between beta-carotene and SOD levels in HIV/AIDS patients (r=-0.174, p=0.217)."

"ABSTRAKLatar belakang: Menurut data tahun 2015 dari WHO dan UNAIDS, ada sekitar 36,7 juta orang di dunia hidup dengan HIV/AIDS. Di Indonesia, berdasarkan data dari Kementerian Kesehatan Republik Indonesia, prevalensi HIV mencapai 0,4 dimana terdapat 232.323 penderita HIV dan 86.780 penderita AIDS yang dilaporkan pada tahun 2016. Kualitas hidup terkait kesehatan pada pasien HIV dapat digunakan sebagai salah satu indikator keberhasilan terapi. Penelitian ini bertujuan untuk mengetahui kesahihan dan keandalan kuesioner WHOQOL-HIV BREF dalam bahasa Indonesia sebagai alat untuk mengukur kualitas hidup pada pasien HIV/AIDS.Metode: Penelitian potong lintang ini dilakukan di Poliklinik khusus HIV RSCM pada bulan November 2016 dengan cara consecutive sampling. Penelitian dilakukan dalam 2 tahap yaitu tahap awal yang merupakan proses adaptasi bahasa dan budaya dan tahap akhir yaitu uji kesahihan dan keandalan dari kuesioner.Hasil : Dari 56 responden yang mengisi kuesioner diketahui bahwa 69,6% laki-laki. Melalui pendekatan multi-trait scaling analysis didapatkan nilai koefisien korelasi yang tinggi terhadap skor total domainnya sehingga dapat dapat dikatakan memiliki validasi yang baik. Korelasi antar domain kuesioner WHOQOL-HIV BREF dan domain kuesioner SF-36 didapatkan 6 domain yang signifikan bermakna (p <0,005) dengan nilai koefisien korelasi kuat (r=0,60-0,79). Keandalan kuesioner dinilai dengan intra class correlation coefficient masing-masing domain 0,401-0,484 dan nilai Alpha Cronbach 0,513-0,798.Kesimpulan: Kuesioner WHOQOL-HIV BREF dalam bahasa Indonesia sahih dan andal. Diharapkan kualitas hidup dapat dipertimbangkan sebagai salah satu acuan respon pengobatan.

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ABSTRACTBackground According to data from WHO and UNAIDS in 2015, approximately 36.7 million people worldwide living with HIV AIDS. In Indonesia, according to the data from the Ministry of Health Republik Indonesia, the HIV prevalence reached 0.4 where 232.323 people living with HIV and 86.780 people already in AIDS stage at 2016. Health status, which contributes to the quality of life in HIV patients, can be used as one indicators of the success of therapy. This study aims to determine the validity and reliability of the questionnaire WHOQOL HIV BREF in Indonesian as a tool for measuring the quality of life of HIV patients.Methods: A cross sectional study was conducted in HIV Integrated Service Unit Cipto Mangunkusumo General Hospital RSCM in November 2016 with consecutive sampling method. The study was conducted in two phases first, the language and cultural adaptation process and second phase was to test the validity and reliability of the questionnaire.Result: Total 56 respondents who filled the questionnaire, 69.6 % of them were men. Through a multi-trait scaling analysis, correlation coefficient value has a high correlation to the total score domain, and thus can be concluded that it has a good validation. Correlation between questionnaire domain WHOQOL-HIV BREF and SF-36 questionnaire domain obtained 6 significant domain (p <0.005) with a strong correlation coefficient (r=0.60 to 0.79). Reliability of the questionnaire was assessed by intra class correlation coefficient, each domain from 0.401 to 0.484 and 0.513 to 0.798 for Cronbach Alpha.Conclusion: The questionnaire WHOQOL-HIV BREF in the Indonesian language is valid and reliable. As such the quality of life can be considered as one criteria of a successful response of HIV treatment."

"ABSTRAKSaat ini proporsi kejadian terinfeksi HIV pada perempuan semakin meningkat. Kualitas hidup pada ibu rumah tangga dengan HIV rendah, hal ini dapat disebabkan oleh banyak faktor seperti HIV disclosure, stigma dan stres. Tujuan : Mengidentifikasi hubungan HIV disclosure, stigma dan stres terhadap kualitas hidup ibu rumah tangga dengan HIV di Kupang, menggunakan desain penelitian cross sectional. Sampel terdiri dari 120 ibu rumah tangga dengan HIV di poli VCT Sobat yang dipilih dengan teknik consecutive sampling. Hasil : Ada hubungan antara stres (p=0,011;α=0,005) dan stigma (p=0,001;α=0,005) dengan kualitas hidup ibu rumah tangga dengan HIV. Faktor paling dominan yang mempengaruhi kualitas hidup ibu rumah tangga dengan HIV adalah tingkat stres sedang (p=0,009;α=0,005; OR=7,667; 95% CI= 1,678-35,032). Kesimpulan : Stres dan stigma berhubungan dengan kualitas hidup ibu rumah tangga denfan HIV di Kupang. Direkomendasikan untuk dilakukan deteksi dini tingkat stres pada ibu rumah tangga dengan HIV agar dapat dilakukan intervensi awal untuk mengurangi stigma dan meningkatkan kualitas hidup.

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ABSTRACTThe proportion of HIV-infected women currently increases. Quality of life in housewives with HIV is low, this can be caused by many factors such as HIV disclosure, stigma and stress. Objective: To identify the relationship between HIV disclosure, stigma and stress on the quality of life of housewives with HIV in Kupang, using a cross sectional study design. The sample consisted of 120 housewives with HIV in poly VCT friends who were selected by consecutive sampling technique. Results: There was a relationship between stress (p = 0.011; α = 0.005) and stigma (p = 0.001; α = 0.005) with the quality of life of housewives with HIV. The most dominant factor affecting the quality of life of housewives with HIV is the moderate stress level (p = 0.009; α = 0.005; OR = 7.667; 95% CI = 1.678-35.032). Conclusion: Stress and stigma are associated with quality of life of housewives with HIV in Kupang. Early detection of stress levels in housewives with HIV is recommended so that early intervention can be carried out to reduce stigma and improve quality of life.

 

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"Tujuan: Penelitian ini adalah studi potong lintang untuk mengetahui hubungan antara kadar vitamin E serum dan aktivitas superoxide dismutase (SOD) eritrosit pada penderita HIV/AIDS. Bahan dan cara: Pengumpulan data dilakukan pada pasien rawat jalan di klinik Pokdisus, RSUPNCM Jakarta selama akhir Februari 2013 sampai bulan Maret 2013. Subyek diperoleh dengan metode consecutive sampling. Sebanyak 52 subjek memenuhi kriteria penelitian. Data dikumpulkan melalui wawancara, rekam medis, dan pengukuran antropometri untuk menilai status gizi, dan pemeriksaan laboratorium yaitu kadar vitamin E serum dan aktivitas SOD eritrosit. Hasil: Sebagian besar subjek adalah laki-laki (51,9%), usia rata-rata adalah 34 ± 4,84 tahun. Malnutrisi terjadi pada 55,8% dari subyek dan semua subyek (100%) memiliki asupan vitamin E yang kurang dari Angka Kecukupan Gizi (AKG) Indonesia. Dalam penelitian ini, sebagian besar subjek telah mendapatkan terapi ARV (94,2%). Jumlah CD4 <200sel/uL ditemukan pada 17 subyek (32,7%). Kadar vitamin E serum yang rendah didapat pada semua subyek (100%) dengan nilai rata-rata kadar vitamin E serum 3,84 (1,77-7,32) umol / L, sementara aktivitas SOD eritrosit yang cukup ditemukan pada 53,8% dari subyek dengan nilai rata-rata 1542,1 ± 281,04 U / g Hb. Kesimpulan: Tidak ada hubungan yang signifikan antara kadar serum vitamin E dan aktivitas SOD ditemukan dalam penelitian ini. (R = 0,047, p = 0,742).

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Objective: The aim of this cross sectional study was to find a correlation between serum level of vitamin E and erythrocyte superoxide dismutase (SOD) activity in HIV/AIDS patients.

Material and method: Data collection was conducted at Pokdisus outpatient clinic, RSUPNCM Jakarta, from late February 2013 to March 2013. Subjects were obtained with the consecutive sampling method. A total of 52 subjects had met the study criteria. Data were collected through interviews, medical records, and anthropometry measurements to assess the nutritional status, and through laboratory examination (i.e. serum level of vitamin E and erythrocyte SOD activity).

Results: The majority of the subjects were male (51,9%) with a mean age of 34 ± 4.84 years. Malnutrition occured in 55.8% of the subjects and all subjects (100%) had vitamin E intake that is less than the Indonesian recommended dietary allowance (RDA). In this study, most subjects had already been on ARV therapy (94.2%). Low CD4 cell count was found in 17 subjects (32.7%). Vitamin E deficiency was found in all subjects (100%) with a median value of serum level of vitamin E of 3.84 (1.77 to 7.32) μmol / L, while normal SOD activity was found in 53.8% of the subjects with a mean value of 1,542.1 ± 281.04 U / g Hb.

Conclusion: No significant correlation between serum level of vitamin E and SOD activity was found in this study (r = 0.047, p = 0.742)."

"AbstrakMen who have sex with men (MSM) comprise a population at risk for HIV infection. Assessing the Quality of Life (QOL) in MSM might be different than other populations. This study showed a secondary analysis from our previous research. It was needed to understand whether peer support and family acceptance had an impact on QOL of MSM living with HIV and ART (Antiretroviral Therapy). A total of 175 respondents were involved in this cross-sectional study that was carried out with purposive sampling. The questionnaires were translated to Bahasa and tested for validity and reliability. Data questionnaires completed were analyzed. Results showed that peer support was positively correlated with QOL (p= 0.023; OR= 2.070), and also, family acceptance was significantly related to QOL (p= 0.001; OR= 2.766). Thus, peer support and family acceptance are important factors affecting the well-being and QOL of MSM living with HIV and ART. This finding can be used for the improvement of QOL in people living with HIV."

"Penelitian ini bertujuan memperoleh pemahaman mendalam tentang makna spiritualitas pada klien HIV/AIDS dalam konteks asuhan keperawatan.Rancangan penelitian ini adalah kualitatif fenomenologi dengan desain deskriptif eksploratif. Penelitian ini memperoleh lima tema yaitu (1) mendekatkan diri kepada Tuhan, (2) menghargai hidup pasca diagnosis HIV, (3) butuh dukungan dari orang terdekat, (4) mempunyai harapan untuk kehidupan yang lebih baik di hari depan,dan (5) kebutuhan spiritual yang tidak terpenuhi. Sebanyak 7 partisipan berpartisipasi menceritakan pengalamannya. Metode wawancara mendalam dan pengamatan lapangan merupakan alat bantu pengumpulan data. Data di analisis menggunakan metode Collaizi (1978). Hasil penelitian menyarankan perawat perlu melakukan pengkajian spiritual pada klien HIV/Aids selama di rawat di RS sehingga perawat dapat memberikan intervensi keperawatan yang tepat untuk membantu klien

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This study aims to explore the meaning of spirituality in HIV / AIDS patients in the nursing care at RSUPN Dr. Cipto Mangunkusumo. This research is a qualitative research phenomenology design with descriptive explorative. There were five themes in this research including more attach to God, respect for life after HIV diagnosis, need a support system, hope for a better life and patient's spiritual need?s were not fulfilled. Seven participants were recruited in this study 7 participants.In-depth interviews, field note and the observation sheet were used to collect data. The seven procedural steps proposed by Collaizi (1978) were utilized in data analysis.The result suggested nurses are supposed to make an assessment for spiritual needs as a nursing intervention and optimize nursing curriculum."

"HIV/AIDS berdampak kepada peningkatan kerentanan terkena infeksi penyakit lain yang berujung kepada kematian. Menurut UNAIDS, Indonesia termasuk ke dalam daftar negara dengan kematian akibat AIDS tidak mengalami penurunan atau laju penurunannya kurang dari 25%. Penelitian ini merupakan penelitian observasional, dengan desain cross sectional yang bertujuan untuk mengetahui gambaran kejadian dan faktor atau determinan utama yang berhubungan dengan kematian berkaitan AIDS pada pasien HIV/AIDS di unit rawat inap Rumah Sakit Cipto Mangunkusumo pada tahun 2008-2012. Sampel penelitian ini sebanyak 207 pasien. Data pasien diambil dengan memanfaatkan data rekam medis pasien untuk melihat variabel independen yang terdiri dari jenis kelamin, umur, pekerjaan, kadar CD4, faktor risiko penularan, jumlah penyakit yang diderita, status gizi, riwayat gangguan syaraf pusat, riwayat konsumsi obat ARV, dan kondisi psikologis untuk nantinya dihubungkan dengan status kematian pasien HIV/AIDS. Analisis data dilakukan hingga analisis multivariat dengan model prediksi.Hasil penelitian menunjukkan bahwa kematian AIDS sebesar 28,5%. Dari hasil analisis multivariat didapatkan 4 variabel yang berhubungan dengan kematian AIDS, yaitu status gizi kurang dari normal (OR=4,75) dengan 95% CI (2,278-9,917), riwayat gangguan syaraf pusat (OR=1,82) dengan 95%CI (1,025-3,251), jumlah penyakit yang diderita lebih dari 5 penyakit (OR=4,09) dengan 95%CI (1,854-9,043), dan kadar CD4. Kadar CD4 menjadi faktor paling berpengaruh terhadap kematian AIDS dengan nilai OR sebesar 5,9 dengan 95%CI 2,096-17,106. Dari hasil penelitian ini dapat direkomendasikan upaya peningkatan awarenessakan pentingnya kontrol kadar CD4 darah untuk pasien HIV/AIDS dan upaya pendukung lainnya untuk mencegah kematian AIDS seperti peningkatan kualitas gizi pasien AIDS, skrining dan deteksi dini gangguan syaraf pusat, dan pencegahan komplikasi penyakit

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HIV/AIDS impact to increased susceptibility to other diseases infections which lead to death. The death of AIDS is also a problem, especially in Indonesia. According to UNAIDS, Indonesia is included in the list of countries where deaths from AIDS do not decline or rate of less than 25% of his descent. This research is observational research, design with cross sectional. This research aims to know the description and the main factors which related to mortality of AIDS HIV/AIDS in inpatient unit RSUPN Dr Cipto Mangunkusumo in 2008-2012. The sample of this research are 207 patients. Data collected by utilizing the patient's medical record data to see the independent variables consisted of gender, age, job, CD4 levels, risk factors of transmission, the amount of illness suffered, nutritional status, history of central nervous disorders, drug consumption history ARV consumption, and psychological conditions to be linked with the status of a patient's death related with HIV/AIDS. The data analysis done to multivariate analysis with prediction model.

The results showed that the AIDS death prevalence reach up to 28.5%. The results of Multivariate analysis obtained 4 variables related to the death of AIDS, poor nutritional status (OR=4,75) with 95% CI (2,278-9,917), central nervous disorder history (OR=1,82) with 95% CI (1,025-3,251), the number of illnesses suffered more than 5 disease (OR=4,09) with 95% CI (1,854-9,043), and CD4 levels. CD4 levels became the most influential factors towards AIDS deaths with a value of 5, 9 OR and 95% CI (2,096-17,106). From the results can be recommended the efforts to increased awareness toward control CD4 blood levels for HIV/AIDS patients and other supporting efforts to prevent deaths of AIDS such as improved quality of nutrition AIDS patients, screening and early detection of central nervous disorders, and prevention of complications of the disease."

"Ketaatan minum obat dalam penanganan HIV/AIDS dengan pengobatan ARV merupakan faktor yang penting dalam menentukan keberhasilan terapi. Di Indonesia belum ada data yang menyebutkan angka pasti ketaatan minum obat ARV pada ODHA. Ketaatan minum obat ARV dipengaruhi oleh adanya faktorfaktor psikologis (stigma diri dan fungsi kognitif) dan non psikologis yang terdiri dari faktor demografi (umur, waktu tempuh tempat tinggal ke rumah sakit, akses berobat, tingkat pendidikan, pekerjaan, tinggal sendiri atau bersama orang lain, pembiayaan berobat, penggunaan NAPZA) dan faktor obat dan penyakit (kompleksitas regimen obat, adanya infeksi oportunistik, sumber transmisi HIV).Hasil penelitian ini menunjukkan bahwa prevalensi ketaatan minum obat ARV pada ODHA yang berobat di UPT HIV RSUPN Cipto Mangunkusumo adalah 67,7%, stigma diri memiliki hubungan yang bermakna dengan ketaatan minum obat ARV, sedangkan faktor non psikologis yang diteliti dan fungsi kognitif tidak memiliki hubungan yang bermakna dengan ketaatan minum obat ARV.

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Adherence to ARV is an important factor in determining the success of HIV/AIDS treatment. There has been no data about adherence to ARV in plwh in indonesia. Adherence to ARV is influenced by psychological factors (self-stigma and cognitive function) and non-psychological factors consisting of demographic (age, travel time between living place and hospital, access to treatment, level of education, occupation, living alone or with others, treatment payment, illicit drugs use), disease and treatment factor (treatment regimen complexity, opportunistic infections, source of HIV transmission).

The result of this study showed that prevalence of adherence to ARV in plwh coming to HIV integrated service unit Cipto Mangunkusumo hospital is 67,7%, that self-stigma had significant relation with adherence to ARV, while psychological factors and cognitive function had no significant relation with adherence to ARV."

"Tujuan: Mengetahui korelasi antara kadar sang (Zn) plasma dengan jumlah Iimfosit CD4 penderita HIV/AIDS.Tempat: Poliklinik Kelompok Studi Khusus (Pokdisus) AIDS Fakultas Kedokteran Universitas Indonesia/RSUPN Dr. Cipto Mangunkusumo, Jakarta.Metodologi: Penelitian potong lintang dilakukan pada 52 orang penderita HIV/AIDS. Wawancara dilakukan pada subyek penelitian untuk mendapatkan data demografi, infeksi oportunistik, asupan energi dan asupan Zn. Data asupan energi didapatkan dengan metode food recall 1x24 jam, sedangkan data asupan Zn didapatkan dengan menggunakan metode FFQ semikuantitatif selama satu bulan terakhir. Status gizi ditentukan berdasarkan IMT. Pemeriksaan laboratorium yang dilakukan meliputi pemeriksaan kadar Zn plasma dan jumlah limfosit CD4. Untuk mengetahui korelasi dipergunakan uji korelasi Pearson dan Spearman-Rank.Hasil: Subyek penelitian terdiri dari 44 orang laki-laki dan delapan orang perempuan, terbanyak berada pada rentang usia 20-29 tahun (80,8%), dengan rerata usia 26,4613,60 tahun, 75% berpendidikan sedang, 63,5% berada di bawab upah minimum propinsi (UMP), Rerata IMT 19,5512,83 kg/m2, 53,8% subyek termasuk kriteria berat badan normal. Nilai rerata asupan energi subyek adalah 1574,11 ± 198,48 kkal/hari, 82,7% subyek mempunyai asupan energi kurang. Rerata asupan Zn 6,9810,92 mglhari, dan 94,2% subyek mempunyai asupan Zn kurang. Median kadar Zn plasma 13,63 (11,26-44,98) µmol/L, 17,3% subyek mengalami defisiensi Zn. Median jumlah limfosit CD4 81 (2-747)/µL., 75% subyek mernpunyai jumlah Iirfosit CD4 < 200/µL. Sebagian besar (80,8%) subyek mengalami infeksi oportunistik, berdasarkan pola infeksi oportunistik, terbanyak adalah kandidiasis orofaring (55,8%). Didapatkan korelasi bermakna antara kadar Zn plasma dengan jumlah limfosit CD4 (r=0,29;p=0,04), dan korelasi tidak bermakna antara asupan Zn dengan kadar Zn plasma (r=0,07; p=0,65) serta antara status gizi (IMT) dengan jumlah limfosit CD4 (r=0,2 I ; p=1,13).Kesimpulan: Didapatkan korelasi bermakna antara kadar Zn plasma dengan jumlah Iimfosit CD4 (r=0,29; p=0,04)

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Objective: To investigate the correlation between plasma zinc (Zn) concentration and the number of CD4 lymphocytes count in HIV/AIDS patients

Methods: This was a cross sectional study of 521-I1V/AIDS patients. Interviews were done to get data about demographic characteristics, opportunistic infections, energi intake and Zn intake. The daily energy intake was assessed using 24h food recall method, while dietary Zn intake was assessed by using semiquantitative FFQ method. Nutritional status was determined BM1. Laboratory examination was done to assess plasma Zn concentration and CD4 lymphocytes count. Pearson's and Spearman's-Rank correlation tests were used to determine the correlation.

Subjects: consisted of forty four (84,6%) males and eight (19,2%) females, most of the subjects were in the 20-29 years old range (80,8%), with mean age of 26,46+3,60 years. Most subjects (75%) had medium education level and 33 subjects (63,5%) were earning under LIMP. Mean value of BMI was 19,55+2,83 kglm2 and based on the BMI levels, most of the subjects were normal (53,8%). Mean daily energy intake were 1574,11 ± 198,48 kcal, 82,7% had Iow energy intake. Mean Zn intake was 6,98 ± 0,92 mg/day, and 94,2% had low Zn intake_ Median plasma Zn concentration was 13,63 (11,26 - 44,98) /µL and 17,3% of subjects had low plasma Zn concentration. Median of CD4 lymphocytes count was 81 (2-747)//µL, 75% subjects had CD4 lymphocytes count < 200//µL, 80,8% subjects had opportunistic infections, and the most prevalent was oesophageal-orofaryng candidiasis (55,8%). There was a significant correlation between Zn plasma level and CD4 lymphocytes count r=0,29; p = 0,04). No significant correlation were found between Zn intake and plasma Zn concentration (r=0,07; p=0,65) and between BMI and CD4 lymphocytes count (r=0,21; p=0,13).

Conclusion: There was significant correlation between Zn plasma level and CD4 lymphocytes count (r = 0,29; p = 0,04)."